Ornithorhynchus anatinus      DNA damage foci


※ DNA damage foci introduction

    DNA damage response proteins such as γH2AX, ATM, 53BP1, RAD51, and the MRE11/RAD50/NBS1 complex, that accumulate and/or are modified in the vicinity of a chromosomal DNA double-strand break to form microscopically visible, subnuclear foci called DNA damage foci, also called (ionizing) radiation‐induced foci (IRIF or RIF) or DNA repair foci. The discovery of DNA damage foci has opened a new dimension to the field of DNA damage signaling. Analysis of the spatiotemporal dynamics of DSB induction and repair in situ or even in live cells has now become a standard method in many different fields (1).

Reference
1. Rothkamm, K., Barnard, S., Moquet, J., Ellender, M., Rana, Z., & Burdak-Rothkamm, S. (2015) DNA damage foci: Meaning and significance. Environ Mol Mutagen, 56(6), 491-504. PMID: 25773265


There are 9 genes.  Reviewed (0 or Unreviewed (9

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Ora-0874
ENSOANG00000011210.3
F7FJ87
2
LLPS-Ora-0950
ENSOANG00000006244.1
F6V0M0
3
LLPS-Ora-1998
ENSOANG00000007264.2
F7CL40
4
LLPS-Ora-2505
ENSOANG00000003647.2
F7FJ30
5
LLPS-Ora-2412
ENSOANG00000011087.2
F7FCV9
ATMIN
6
LLPS-Ora-3078
ENSOANG00000005606.4
F7BAJ3
FUS
7
LLPS-Ora-0973
ENSOANG00000007257.1
F6PSG7
H2AFX
8
LLPS-Ora-3328
ENSOANG00000008019.3
F7EPF8
RAD50
9
LLPS-Ora-2009
ENSOANG00000008627.3
F6WLK8
RBM45