※ DNA damage foci introduction

    DNA damage response proteins such as γH2AX, ATM, 53BP1, RAD51, and the MRE11/RAD50/NBS1 complex, that accumulate and/or are modified in the vicinity of a chromosomal DNA double-strand break to form microscopically visible, subnuclear foci called DNA damage foci, also called (ionizing) radiation‐induced foci (IRIF or RIF) or DNA repair foci. The discovery of DNA damage foci has opened a new dimension to the field of DNA damage signaling. Analysis of the spatiotemporal dynamics of DSB induction and repair in situ or even in live cells has now become a standard method in many different fields (1).

Reference
1. Rothkamm, K., Barnard, S., Moquet, J., Ellender, M., Rana, Z., & Burdak-Rothkamm, S. (2015) DNA damage foci: Meaning and significance. Environ Mol Mutagen, 56(6), 491-504. PMID: 25773265

  Reviewed (0)  or Unreviewed (11) 

No.	Status	DrLLPS ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		LLPS-Nol-1839	ENSNLEG00000007230.3	G1R6K1	ATM
2		LLPS-Nol-2481	ENSNLEG00000029083.1	A0A2I3GXC4	ATMIN
3		LLPS-Nol-0361	ENSNLEG00000004792.3	A0A2I3FYG5	ATR
4		LLPS-Nol-3027	ENSNLEG00000016218.3	G1S2J4	FUS
5		LLPS-Nol-0801	ENSNLEG00000028254.1	A0A2I3H5M9	H2AFX
6		LLPS-Nol-0785	ENSNLEG00000002473.3	G1QQE9	HDAC1
7		LLPS-Nol-1503	ENSNLEG00000013252.3	G1RS97	PRKDC
8		LLPS-Nol-1113	ENSNLEG00000012738.2	G1RQJ8	RAD50
9		LLPS-Nol-0176	ENSNLEG00000003137.3	A0A2I3H1V5	RAD51
10		LLPS-Nol-0866	ENSNLEG00000006080.2	G1R2E4	RBM45
11		LLPS-Nol-2050	ENSNLEG00000005009.2	G1QYZ4	TP53BP1