Myotis lucifugus      DNA damage foci


※ DNA damage foci introduction

    DNA damage response proteins such as γH2AX, ATM, 53BP1, RAD51, and the MRE11/RAD50/NBS1 complex, that accumulate and/or are modified in the vicinity of a chromosomal DNA double-strand break to form microscopically visible, subnuclear foci called DNA damage foci, also called (ionizing) radiation‐induced foci (IRIF or RIF) or DNA repair foci. The discovery of DNA damage foci has opened a new dimension to the field of DNA damage signaling. Analysis of the spatiotemporal dynamics of DSB induction and repair in situ or even in live cells has now become a standard method in many different fields (1).

Reference
1. Rothkamm, K., Barnard, S., Moquet, J., Ellender, M., Rana, Z., & Burdak-Rothkamm, S. (2015) DNA damage foci: Meaning and significance. Environ Mol Mutagen, 56(6), 491-504. PMID: 25773265


There are 11 genes.  Reviewed (0 or Unreviewed (11

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Myl-0575
ENSMLUG00000004806.2
G1P397
2
LLPS-Myl-1200
ENSMLUG00000005888.2
G1P5S6
3
LLPS-Myl-2085
ENSMLUG00000008972.2
G1PCR2
4
LLPS-Myl-2757
ENSMLUG00000011166.2
G1PHV0
5
LLPS-Myl-2171
ENSMLUG00000016908.2
G1PVP1
ATR
6
LLPS-Myl-1507
ENSMLUG00000004816.2
G1P399
H2AFX
7
LLPS-Myl-3579
ENSMLUG00000013837.2
G1PNQ7
HDAC1
8
LLPS-Myl-3855
ENSMLUG00000000718.2
G1NU10
PRKDC
9
LLPS-Myl-3896
ENSMLUG00000016559.2
G1PUW7
RAD50
10
LLPS-Myl-2666
ENSMLUG00000004275.2
G1QDW3
RAD51
11
LLPS-Myl-1332
ENSMLUG00000005782.2
G1P5J4
RBM45