Mustela putorius furo      DNA damage foci


※ DNA damage foci introduction

    DNA damage response proteins such as γH2AX, ATM, 53BP1, RAD51, and the MRE11/RAD50/NBS1 complex, that accumulate and/or are modified in the vicinity of a chromosomal DNA double-strand break to form microscopically visible, subnuclear foci called DNA damage foci, also called (ionizing) radiation‐induced foci (IRIF or RIF) or DNA repair foci. The discovery of DNA damage foci has opened a new dimension to the field of DNA damage signaling. Analysis of the spatiotemporal dynamics of DSB induction and repair in situ or even in live cells has now become a standard method in many different fields (1).

Reference
1. Rothkamm, K., Barnard, S., Moquet, J., Ellender, M., Rana, Z., & Burdak-Rothkamm, S. (2015) DNA damage foci: Meaning and significance. Environ Mol Mutagen, 56(6), 491-504. PMID: 25773265


There are 10 genes.  Reviewed (0 or Unreviewed (10

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Mup-0160
ENSMPUG00000008548.1
M3YAX6
2
LLPS-Mup-0461
ENSMPUG00000004035.1
M3XY50
3
LLPS-Mup-2926
ENSMPUG00000010515.1
M3YGI1
4
LLPS-Mup-0014
ENSMPUG00000005971.1
M3Y3L9
ATM
5
LLPS-Mup-3859
ENSMPUG00000009728.1
M3YE95
ATMIN
6
LLPS-Mup-3435
ENSMPUG00000012022.1
M3YKS3
ATR
7
LLPS-Mup-2619
ENSMPUG00000015231.1
G9K3X3
HDAC1
8
LLPS-Mup-1688
ENSMPUG00000001020.1
M3XPL2
PRKDC
9
LLPS-Mup-3139
ENSMPUG00000003205.1
M3XVS2
RBM45
10
LLPS-Mup-3290
ENSMPUG00000010262.1
M3YFT0
TP53BP1