Meleagris gallopavo      DNA damage foci


※ DNA damage foci introduction

    DNA damage response proteins such as γH2AX, ATM, 53BP1, RAD51, and the MRE11/RAD50/NBS1 complex, that accumulate and/or are modified in the vicinity of a chromosomal DNA double-strand break to form microscopically visible, subnuclear foci called DNA damage foci, also called (ionizing) radiation‐induced foci (IRIF or RIF) or DNA repair foci. The discovery of DNA damage foci has opened a new dimension to the field of DNA damage signaling. Analysis of the spatiotemporal dynamics of DSB induction and repair in situ or even in live cells has now become a standard method in many different fields (1).

Reference
1. Rothkamm, K., Barnard, S., Moquet, J., Ellender, M., Rana, Z., & Burdak-Rothkamm, S. (2015) DNA damage foci: Meaning and significance. Environ Mol Mutagen, 56(6), 491-504. PMID: 25773265


There are 9 genes.  Reviewed (0 or Unreviewed (9

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Meg-1646
ENSMGAG00000008972.2
G1N9X5
2
LLPS-Meg-1280
ENSMGAG00000015148.2
G1NQH3
ATM
3
LLPS-Meg-2646
ENSMGAG00000006738.1
G1N4J8
ATMIN
4
LLPS-Meg-1999
ENSMGAG00000006227.2
G1N3I9
ATR
5
LLPS-Meg-0419
ENSMGAG00000011845.2
G1NH10
H2AFX
6
LLPS-Meg-0716
ENSMGAG00000010711.2
G1NE83
PRKDC
7
LLPS-Meg-1764
ENSMGAG00000002998.2
G1MVI4
RAD51
8
LLPS-Meg-0795
ENSMGAG00000009496.1
G1NB49
RBM45
9
LLPS-Meg-0091
ENSMGAG00000010760.2
G1NE63
TP53BP1