Macaca nemestrina      DNA damage foci


※ DNA damage foci introduction

    DNA damage response proteins such as γH2AX, ATM, 53BP1, RAD51, and the MRE11/RAD50/NBS1 complex, that accumulate and/or are modified in the vicinity of a chromosomal DNA double-strand break to form microscopically visible, subnuclear foci called DNA damage foci, also called (ionizing) radiation‐induced foci (IRIF or RIF) or DNA repair foci. The discovery of DNA damage foci has opened a new dimension to the field of DNA damage signaling. Analysis of the spatiotemporal dynamics of DSB induction and repair in situ or even in live cells has now become a standard method in many different fields (1).

Reference
1. Rothkamm, K., Barnard, S., Moquet, J., Ellender, M., Rana, Z., & Burdak-Rothkamm, S. (2015) DNA damage foci: Meaning and significance. Environ Mol Mutagen, 56(6), 491-504. PMID: 25773265


There are 12 genes.  Reviewed (0 or Unreviewed (12

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Man-0881
ENSMNEG00000036941.1
A0A2K6CUH2
2
LLPS-Man-1370
ENSMNEG00000035431.1
A0A2K6CKB5
3
LLPS-Man-2619
ENSMNEG00000004901.1
A0A2K6APS3
ATM
4
LLPS-Man-0788
ENSMNEG00000040533.1
A0A2K6DFK6
ATMIN
5
LLPS-Man-0908
ENSMNEG00000006874.1
A0A2K6AR03
ATR
6
LLPS-Man-1652
ENSMNEG00000027646.1
A0A2K6B648
FUS
7
LLPS-Man-2464
ENSMNEG00000021267.1
A0A2K6AZQ4
H2AFX
8
LLPS-Man-1502
ENSMNEG00000044964.1
A0A2K6E9H8
MDC1
9
LLPS-Man-3752
ENSMNEG00000040666.1
A0A2K6DHN9
PRKDC
10
LLPS-Man-0009
ENSMNEG00000028901.1
A0A2K6BBX8
RAD51
11
LLPS-Man-4287
ENSMNEG00000029136.1
A0A2K6BDA3
RBM45
12
LLPS-Man-3043
ENSMNEG00000038881.1
A0A2K6D5C0
TP53BP1