Lepisosteus oculatus      DNA damage foci


※ DNA damage foci introduction

    DNA damage response proteins such as γH2AX, ATM, 53BP1, RAD51, and the MRE11/RAD50/NBS1 complex, that accumulate and/or are modified in the vicinity of a chromosomal DNA double-strand break to form microscopically visible, subnuclear foci called DNA damage foci, also called (ionizing) radiation‐induced foci (IRIF or RIF) or DNA repair foci. The discovery of DNA damage foci has opened a new dimension to the field of DNA damage signaling. Analysis of the spatiotemporal dynamics of DSB induction and repair in situ or even in live cells has now become a standard method in many different fields (1).

Reference
1. Rothkamm, K., Barnard, S., Moquet, J., Ellender, M., Rana, Z., & Burdak-Rothkamm, S. (2015) DNA damage foci: Meaning and significance. Environ Mol Mutagen, 56(6), 491-504. PMID: 25773265


There are 6 genes.  Reviewed (0 or Unreviewed (6

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Leo-1174
ENSLOCG00000006046.1
W5MG32
2
LLPS-Leo-2157
ENSLOCG00000010392.1
W5MWI4
3
LLPS-Leo-3073
ENSLOCG00000012707.1
W5N4S7
4
LLPS-Leo-3546
ENSLOCG00000014193.1
W5NA27
5
LLPS-Leo-3622
ENSLOCG00000000709.1
W5LXD0
6
LLPS-Leo-3949
ENSLOCG00000006862.1
W5MIU1