Ficedula albicollis      DNA damage foci


※ DNA damage foci introduction

    DNA damage response proteins such as γH2AX, ATM, 53BP1, RAD51, and the MRE11/RAD50/NBS1 complex, that accumulate and/or are modified in the vicinity of a chromosomal DNA double-strand break to form microscopically visible, subnuclear foci called DNA damage foci, also called (ionizing) radiation‐induced foci (IRIF or RIF) or DNA repair foci. The discovery of DNA damage foci has opened a new dimension to the field of DNA damage signaling. Analysis of the spatiotemporal dynamics of DSB induction and repair in situ or even in live cells has now become a standard method in many different fields (1).

Reference
1. Rothkamm, K., Barnard, S., Moquet, J., Ellender, M., Rana, Z., & Burdak-Rothkamm, S. (2015) DNA damage foci: Meaning and significance. Environ Mol Mutagen, 56(6), 491-504. PMID: 25773265


There are 7 genes.  Reviewed (0 or Unreviewed (7

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Fia-2755
ENSFALG00000000452.1
U3JCG0
ATM
2
LLPS-Fia-1874
ENSFALG00000006834.1
U3JWH4
ATMIN
3
LLPS-Fia-3216
ENSFALG00000007034.1
U3JX48
ATR
4
LLPS-Fia-3053
ENSFALG00000005785.1
U3JTC7
PRKDC
5
LLPS-Fia-2360
ENSFALG00000013456.1
U3KG88
RAD50
6
LLPS-Fia-0772
ENSFALG00000003330.1
U3JL26
RBM45
7
LLPS-Fia-1628
ENSFALG00000011406.1
U3KA52
TP53BP1