※ DNA damage foci introduction

    DNA damage response proteins such as γH2AX, ATM, 53BP1, RAD51, and the MRE11/RAD50/NBS1 complex, that accumulate and/or are modified in the vicinity of a chromosomal DNA double-strand break to form microscopically visible, subnuclear foci called DNA damage foci, also called (ionizing) radiation‐induced foci (IRIF or RIF) or DNA repair foci. The discovery of DNA damage foci has opened a new dimension to the field of DNA damage signaling. Analysis of the spatiotemporal dynamics of DSB induction and repair in situ or even in live cells has now become a standard method in many different fields (1).

Reference
1. Rothkamm, K., Barnard, S., Moquet, J., Ellender, M., Rana, Z., & Burdak-Rothkamm, S. (2015) DNA damage foci: Meaning and significance. Environ Mol Mutagen, 56(6), 491-504. PMID: 25773265

  Reviewed (0)  or Unreviewed (12) 

No.	Status	DrLLPS ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		LLPS-Eqc-1372	ENSECAG00000031050.1
2		LLPS-Eqc-1967	ENSECAG00000029766.1
3		LLPS-Eqc-1738	ENSECAG00000021147.2	F6X5V1	ATM
4		LLPS-Eqc-2441	ENSECAG00000011923.2	F7BEG3	ATMIN
5		LLPS-Eqc-3753	ENSECAG00000013285.3	F6T1S2	ATR
6		LLPS-Eqc-0226	ENSECAG00000016082.2	F7DUN1	HDAC1
7		LLPS-Eqc-3787	ENSECAG00000011057.2	F7AQM7	MDC1
8		LLPS-Eqc-1322	ENSECAG00000020168.2	F6RGR8	PRKDC
9		LLPS-Eqc-1953	ENSECAG00000010922.2	F7AR56	RAD50
10		LLPS-Eqc-0952	ENSECAG00000017647.2	F6SWI3	RAD51
11		LLPS-Eqc-4133	ENSECAG00000017129.2	F6WNH7	RBM45
12		LLPS-Eqc-1388	ENSECAG00000008093.2	F6UBL0	TP53BP1