Dipodomys ordii      DNA damage foci


※ DNA damage foci introduction

    DNA damage response proteins such as γH2AX, ATM, 53BP1, RAD51, and the MRE11/RAD50/NBS1 complex, that accumulate and/or are modified in the vicinity of a chromosomal DNA double-strand break to form microscopically visible, subnuclear foci called DNA damage foci, also called (ionizing) radiation‐induced foci (IRIF or RIF) or DNA repair foci. The discovery of DNA damage foci has opened a new dimension to the field of DNA damage signaling. Analysis of the spatiotemporal dynamics of DSB induction and repair in situ or even in live cells has now become a standard method in many different fields (1).

Reference
1. Rothkamm, K., Barnard, S., Moquet, J., Ellender, M., Rana, Z., & Burdak-Rothkamm, S. (2015) DNA damage foci: Meaning and significance. Environ Mol Mutagen, 56(6), 491-504. PMID: 25773265


There are 10 genes.  Reviewed (0 or Unreviewed (10

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Dio-0569
ENSDORG00000013688.2
A0A1S3ELJ1
Atm
2
LLPS-Dio-4000
ENSDORG00000029539.1
A0A1S3EVM5
Atmin
3
LLPS-Dio-3298
ENSDORG00000000389.2
A0A1S3GAR1
Atr
4
LLPS-Dio-0100
ENSDORG00000014218.2
A0A1S3ERL6
Fus
5
LLPS-Dio-2387
ENSDORG00000023194.1
A0A1S3GMM2
LOC105998920
6
LLPS-Dio-2410
ENSDORG00000001977.2
A0A1S3GVT6
LOC106002021
7
LLPS-Dio-3355
ENSDORG00000004417.2
A0A1S3EMJ3
Prkdc
8
LLPS-Dio-2170
ENSDORG00000029657.1
A0A1S3ENF2
Rad51
9
LLPS-Dio-4211
ENSDORG00000015831.2
A0A1S3GBT0
Rbm45
10
LLPS-Dio-1031
ENSDORG00000011558.2
A0A1S3ENQ6
Tp53bp1