Chlorocebus sabaeus      DNA damage foci


※ DNA damage foci introduction

    DNA damage response proteins such as γH2AX, ATM, 53BP1, RAD51, and the MRE11/RAD50/NBS1 complex, that accumulate and/or are modified in the vicinity of a chromosomal DNA double-strand break to form microscopically visible, subnuclear foci called DNA damage foci, also called (ionizing) radiation‐induced foci (IRIF or RIF) or DNA repair foci. The discovery of DNA damage foci has opened a new dimension to the field of DNA damage signaling. Analysis of the spatiotemporal dynamics of DSB induction and repair in situ or even in live cells has now become a standard method in many different fields (1).

Reference
1. Rothkamm, K., Barnard, S., Moquet, J., Ellender, M., Rana, Z., & Burdak-Rothkamm, S. (2015) DNA damage foci: Meaning and significance. Environ Mol Mutagen, 56(6), 491-504. PMID: 25773265


There are 11 genes.  Reviewed (0 or Unreviewed (11

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Chs-1202
ENSCSAG00000007549.1
A0A0D9R5C5
2
LLPS-Chs-1938
ENSCSAG00000013792.1
A0A0D9RMV7
3
LLPS-Chs-2253
ENSCSAG00000001053.1
A0A0D9S7X1
4
LLPS-Chs-0338
ENSCSAG00000002971.1
A0A0D9S2I2
ATM
5
LLPS-Chs-2107
ENSCSAG00000003568.1
A0A0D9S0U0
ATMIN
6
LLPS-Chs-1968
ENSCSAG00000011281.1
A0A0D9RFU3
ATR
7
LLPS-Chs-1557
ENSCSAG00000005711.1
A0A0D9R082
FUS
8
LLPS-Chs-0720
ENSCSAG00000000595.1
A0A0D9S972
H2AFX
9
LLPS-Chs-2572
ENSCSAG00000014860.1
A0A0D9RQR8
PRKDC
10
LLPS-Chs-0778
ENSCSAG00000014231.1
A0A0D9RP29
RBM45
11
LLPS-Chs-2286
ENSCSAG00000009121.1
A0A0D9R9T7
TP53BP1