Cercocebus atys      DNA damage foci


※ DNA damage foci introduction

    DNA damage response proteins such as γH2AX, ATM, 53BP1, RAD51, and the MRE11/RAD50/NBS1 complex, that accumulate and/or are modified in the vicinity of a chromosomal DNA double-strand break to form microscopically visible, subnuclear foci called DNA damage foci, also called (ionizing) radiation‐induced foci (IRIF or RIF) or DNA repair foci. The discovery of DNA damage foci has opened a new dimension to the field of DNA damage signaling. Analysis of the spatiotemporal dynamics of DSB induction and repair in situ or even in live cells has now become a standard method in many different fields (1).

Reference
1. Rothkamm, K., Barnard, S., Moquet, J., Ellender, M., Rana, Z., & Burdak-Rothkamm, S. (2015) DNA damage foci: Meaning and significance. Environ Mol Mutagen, 56(6), 491-504. PMID: 25773265


There are 11 genes.  Reviewed (0 or Unreviewed (11

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Cea-4579
ENSCATG00000040968.1
A0A2K5NFW5
2
LLPS-Cea-1207
ENSCATG00000039377.1
A0A2K5N5E5
ATM
3
LLPS-Cea-2521
ENSCATG00000041468.1
A0A2K5NIZ6
ATMIN
4
LLPS-Cea-0097
ENSCATG00000034316.1
A0A2K5M7R9
ATR
5
LLPS-Cea-2513
ENSCATG00000034413.1
A0A2K5M862
FUS
6
LLPS-Cea-2746
ENSCATG00000017934.1
A0A2K5KXP0
H2AFX
7
LLPS-Cea-0582
ENSCATG00000044204.1
A0A2K5P110
HDAC1
8
LLPS-Cea-1457
ENSCATG00000035100.1
A0A2K5MD69
PRKDC
9
LLPS-Cea-1224
ENSCATG00000033634.1
A0A2K5M3G5
RAD51
10
LLPS-Cea-1048
ENSCATG00000041082.1
A0A2K5NGM3
RBM45
11
LLPS-Cea-2653
ENSCATG00000032845.1
A0A2K5LZ71
TP53BP1