※ DNA damage foci introduction

    DNA damage response proteins such as γH2AX, ATM, 53BP1, RAD51, and the MRE11/RAD50/NBS1 complex, that accumulate and/or are modified in the vicinity of a chromosomal DNA double-strand break to form microscopically visible, subnuclear foci called DNA damage foci, also called (ionizing) radiation‐induced foci (IRIF or RIF) or DNA repair foci. The discovery of DNA damage foci has opened a new dimension to the field of DNA damage signaling. Analysis of the spatiotemporal dynamics of DSB induction and repair in situ or even in live cells has now become a standard method in many different fields (1).

Reference
1. Rothkamm, K., Barnard, S., Moquet, J., Ellender, M., Rana, Z., & Burdak-Rothkamm, S. (2015) DNA damage foci: Meaning and significance. Environ Mol Mutagen, 56(6), 491-504. PMID: 25773265

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No.	Status	DrLLPS ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		LLPS-Caj-0534	ENSCJAG00000010159.3	F7CXB7	ATM
2		LLPS-Caj-4295	ENSCJAG00000016670.3	U3C6V0	ATMIN
3		LLPS-Caj-2151	ENSCJAG00000001797.3	F7E9U4	ATR
4		LLPS-Caj-2825	ENSCJAG00000003169.3	F7HVN9	FUS
5		LLPS-Caj-2080	ENSCJAG00000042532.1	U3CDD7	H2AFX
6		LLPS-Caj-2429	ENSCJAG00000000970.3	F7CCQ4	HDAC1
7		LLPS-Caj-4217	ENSCJAG00000019900.4	F6PRU9	MDC1
8		LLPS-Caj-2717	ENSCJAG00000013572.3	F7CGE9	PRKDC
9		LLPS-Caj-3087	ENSCJAG00000033428.3	B0KWP2	RAD50
10		LLPS-Caj-1810	ENSCJAG00000020821.3	F7IG78	RAD51
11		LLPS-Caj-0976	ENSCJAG00000021516.3	F7IJ91	RBM45
12		LLPS-Caj-3425	ENSCJAG00000002786.3	F6TFC1	TP53BP1