Bos taurus      DNA damage foci


※ DNA damage foci introduction

    DNA damage response proteins such as γH2AX, ATM, 53BP1, RAD51, and the MRE11/RAD50/NBS1 complex, that accumulate and/or are modified in the vicinity of a chromosomal DNA double-strand break to form microscopically visible, subnuclear foci called DNA damage foci, also called (ionizing) radiation‐induced foci (IRIF or RIF) or DNA repair foci. The discovery of DNA damage foci has opened a new dimension to the field of DNA damage signaling. Analysis of the spatiotemporal dynamics of DSB induction and repair in situ or even in live cells has now become a standard method in many different fields (1).

Reference
1. Rothkamm, K., Barnard, S., Moquet, J., Ellender, M., Rana, Z., & Burdak-Rothkamm, S. (2015) DNA damage foci: Meaning and significance. Environ Mol Mutagen, 56(6), 491-504. PMID: 25773265


There are 10 genes.  Reviewed (1 or Unreviewed (9

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Bot-0077
ENSBTAG00000005757.6
Q28009
FUS
2
LLPS-Bot-1781
ENSBTAG00000003111.5
E1BEI6
ATM
3
LLPS-Bot-2370
ENSBTAG00000008213.6
F1MEP8
ATMIN
4
LLPS-Bot-1638
ENSBTAG00000011529.6
F1MLY7
ATR
5
LLPS-Bot-2610
ENSBTAG00000012698.6
Q32PJ8
HDAC1
6
LLPS-Bot-2299
ENSBTAG00000017019.6
E1BLB6
PRKDC
7
LLPS-Bot-3690
ENSBTAG00000011252.6
G3X6W2
RAD50
8
LLPS-Bot-1331
ENSBTAG00000002918.4
Q2KJ94
RAD51
9
LLPS-Bot-4376
ENSBTAG00000006168.5
Q3MHF0
RBM45
10
LLPS-Bot-3855
ENSBTAG00000021304.5
E1BDS6
TP53BP1