Arabidopsis lyrata      DNA damage foci


※ DNA damage foci introduction

    DNA damage response proteins such as γH2AX, ATM, 53BP1, RAD51, and the MRE11/RAD50/NBS1 complex, that accumulate and/or are modified in the vicinity of a chromosomal DNA double-strand break to form microscopically visible, subnuclear foci called DNA damage foci, also called (ionizing) radiation‐induced foci (IRIF or RIF) or DNA repair foci. The discovery of DNA damage foci has opened a new dimension to the field of DNA damage signaling. Analysis of the spatiotemporal dynamics of DSB induction and repair in situ or even in live cells has now become a standard method in many different fields (1).

Reference
1. Rothkamm, K., Barnard, S., Moquet, J., Ellender, M., Rana, Z., & Burdak-Rothkamm, S. (2015) DNA damage foci: Meaning and significance. Environ Mol Mutagen, 56(6), 491-504. PMID: 25773265


There are 4 genes.  Reviewed (0 or Unreviewed (4

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Arl-1029
fgenesh1_pm.C_scaffold_5000964
D7LRJ8
ARALYDRAFT_323420
2
LLPS-Arl-0220
fgenesh1_pm.C_scaffold_7000002
D7MEW2
ARALYDRAFT_327775
3
LLPS-Arl-2703
fgenesh2_kg.8__2743__AT5G66730.1
D7MMD7
ARALYDRAFT_496927
4
LLPS-Arl-2275
scaffold_703887.1
D7MJ32
ARALYDRAFT_916145