Aotus nancymaae      DNA damage foci


※ DNA damage foci introduction

    DNA damage response proteins such as γH2AX, ATM, 53BP1, RAD51, and the MRE11/RAD50/NBS1 complex, that accumulate and/or are modified in the vicinity of a chromosomal DNA double-strand break to form microscopically visible, subnuclear foci called DNA damage foci, also called (ionizing) radiation‐induced foci (IRIF or RIF) or DNA repair foci. The discovery of DNA damage foci has opened a new dimension to the field of DNA damage signaling. Analysis of the spatiotemporal dynamics of DSB induction and repair in situ or even in live cells has now become a standard method in many different fields (1).

Reference
1. Rothkamm, K., Barnard, S., Moquet, J., Ellender, M., Rana, Z., & Burdak-Rothkamm, S. (2015) DNA damage foci: Meaning and significance. Environ Mol Mutagen, 56(6), 491-504. PMID: 25773265


There are 10 genes.  Reviewed (0 or Unreviewed (10

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Aon-1692
ENSANAG00000038200.1
A0A2K5F8S9
2
LLPS-Aon-2022
ENSANAG00000021591.1
A0A2K5CEH5
3
LLPS-Aon-2567
ENSANAG00000029587.1
A0A2K5DRS5
4
LLPS-Aon-2680
ENSANAG00000011935.1
A0A2K5BZ30
5
LLPS-Aon-1585
ENSANAG00000023573.1
A0A2K5CRJ4
ATM
6
LLPS-Aon-0237
ENSANAG00000025376.1
A0A2K5D241
ATR
7
LLPS-Aon-0757
ENSANAG00000022911.1
A0A2K5CMG8
HDAC1
8
LLPS-Aon-1707
ENSANAG00000028345.1
A0A2K5DLE5
PRKDC
9
LLPS-Aon-4308
ENSANAG00000034660.1
A0A2K5ELF6
RBM45
10
LLPS-Aon-2851
ENSANAG00000009073.1
A0A2K5BY80
TP53BP1