Anas platyrhynchos      DNA damage foci


※ DNA damage foci introduction

    DNA damage response proteins such as γH2AX, ATM, 53BP1, RAD51, and the MRE11/RAD50/NBS1 complex, that accumulate and/or are modified in the vicinity of a chromosomal DNA double-strand break to form microscopically visible, subnuclear foci called DNA damage foci, also called (ionizing) radiation‐induced foci (IRIF or RIF) or DNA repair foci. The discovery of DNA damage foci has opened a new dimension to the field of DNA damage signaling. Analysis of the spatiotemporal dynamics of DSB induction and repair in situ or even in live cells has now become a standard method in many different fields (1).

Reference
1. Rothkamm, K., Barnard, S., Moquet, J., Ellender, M., Rana, Z., & Burdak-Rothkamm, S. (2015) DNA damage foci: Meaning and significance. Environ Mol Mutagen, 56(6), 491-504. PMID: 25773265


There are 9 genes.  Reviewed (0 or Unreviewed (9

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Anp-0046
ENSAPLG00000010574.1
U3IST5
2
LLPS-Anp-0094
ENSAPLG00000012735.1
U3IZG4
ATM
3
LLPS-Anp-2129
ENSAPLG00000009633.1
U3IQ15
ATMIN
4
LLPS-Anp-1700
ENSAPLG00000003751.1
U3I7Y8
ATR
5
LLPS-Anp-1140
ENSAPLG00000014752.1
U3J575
HDAC1
6
LLPS-Anp-2721
ENSAPLG00000002697.1
U3I4N6
PRKDC
7
LLPS-Anp-1766
ENSAPLG00000011856.1
U3IWN7
RAD50
8
LLPS-Anp-0940
ENSAPLG00000004452.1
R0KMM6
RAD51
9
LLPS-Anp-3359
ENSAPLG00000011049.1
R0K7E9
RBM45