Latimeria chalumnae      DDX1 body


※ DDX1 body introduction

    Eukaryotic cells are inhomogeneously crowded with biological macromolecules (proteins and nucleic acids) and often contain numerous cellular bodies, including proteinaceous membrane-less organelles (PMLOs), They are formed as a result of highly regulated and reversible liquid-liquid demixing phase separation and represent condensed liquid droplets, which are invariantly enriched in intrinsically disordered proteins (1), DDX1 bodies is a kind of these bodies located in nucleus, It is fluid and related to the pre-mRNA processing (1).

Reference
1. Uversky, V. N. (2017) Intrinsically disordered proteins in overcrowded milieu: Membrane-less organelles, phase separation, and intrinsic disorder. Curr Opin Struct Biol, 44, 18-30. PMID: 27838525


There are 2 genes.  Reviewed (0 or Unreviewed (2

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Lac-2317
ENSLACG00000015927.1
H3B855
CSTF2
2
LLPS-Lac-0866
ENSLACG00000010529.1
H3AQP2
DDX1