Takifugu rubripes      Chromatoid body


※ Chromatoid body introduction

    A single large granule of nuage, presents in post-meiotic spermatids is called the chromatoid body (1). Multiple proteins and some mRNAs have been found to localized to the chromatoid body including mouse VASA homolog , tudor-domain containing 1 (TDRD1), tudor-domain containing 6 (TDRD6), and tudor-domain containing 7 (TDRD7) , transition protein 2 (Tnp2), RANBP9, as a known MVH interactor also localizes to it. Its formation is related to the coalescence of intermitochondrial cement granules. In fact, the formation of the chromatoid body is not required for microRNA biogenesis, but might be important for its action on target mRNAs (1). In mice, the chromatoid body is a structure resembles Gp, TDRD6 plays a role in establishing the body and the localization of piRNA pathway components to this body (2).

Reference
1. Woodruff, J. B., Hyman, A. A., & Boke, E. (2018) Organization and Function of Non-dynamic Biomolecular Condensates. Trends Biochem Sci, 43(2), 81-94. PMID: 30086300
2. Ma, L., Buchold, G. M., Greenbaum, M. P., Roy, A., Burns, K. H., Zhu, H., et al. (2009) GASZ is essential for male meiosis and suppression of retrotransposon expression in the male germline. PLoS Genet, 5(9), e1000635. PMID: 19730684


There are 76 genes.  Reviewed (0 or Unreviewed (76

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Tar-0430
ENSTRUG00000007440.2
H2T169
2
LLPS-Tar-1471
ENSTRUG00000000464.2
H2RLT0
3
LLPS-Tar-1622
ENSTRUG00000009391.2
H2TG06
4
LLPS-Tar-3965
ENSTRUG00000025300.1
A0A3B5K7C5
5
LLPS-Tar-0748
ENSTRUG00000008514.2
H2T9J1
adad1
6
LLPS-Tar-4019
ENSTRUG00000011709.2
H2TY17
afap1l2
7
LLPS-Tar-1932
ENSTRUG00000007370.2
H2T0M8
ago2
8
LLPS-Tar-2035
ENSTRUG00000017140.2
A0A3B5KJ08
asz1
9
LLPS-Tar-1501
ENSTRUG00000000673.2
H2RN95
casc3
10
LLPS-Tar-3519
ENSTRUG00000005735.2
A0A3B5KB31
cd74
11
LLPS-Tar-3217
ENSTRUG00000000676.2
H2RNA1
cenpv
12
LLPS-Tar-0751
ENSTRUG00000025415.1
A0A3B5K1D0
cnbp
13
LLPS-Tar-2687
ENSTRUG00000018675.2
Q8HCW3
COI
14
LLPS-Tar-0617
ENSTRUG00000003429.2
H2S6N4
dcp1a
15
LLPS-Tar-1070
ENSTRUG00000015765.2
H2UTK8
ddx1
16
LLPS-Tar-1129
ENSTRUG00000002356.2
H2RZ56
DDX5
17
LLPS-Tar-1674
ENSTRUG00000006156.2
H2SRC4
dicer1
18
LLPS-Tar-0773
ENSTRUG00000005353.2
H2SKB6
edc4
19
LLPS-Tar-1679
ENSTRUG00000011543.2
H2TWV1
eif4a3
20
LLPS-Tar-2016
ENSTRUG00000021926.1
A0A3B5KC71
ewsr1
21
LLPS-Tar-1367
ENSTRUG00000016234.2
H2UX24
fyco1
22
LLPS-Tar-3710
ENSTRUG00000018245.2
H2VBV2
GPX4 (1 of many)
23
LLPS-Tar-1115
ENSTRUG00000020069.1
A0A3B5KQZ9
hnrnph1
24
LLPS-Tar-1222
ENSTRUG00000013783.2
H2UE48
hnrnpm
25
LLPS-Tar-1161
ENSTRUG00000007759.2
A0A3B5JZ99
hnrnpu
26
LLPS-Tar-0857
ENSTRUG00000010961.2
H2TSL9
ilf3
27
LLPS-Tar-3457
ENSTRUG00000020902.1
A0A3B5KFP2
lamp1
28
LLPS-Tar-0520
ENSTRUG00000010653.2
A0A3B5K2B5
LOC101061360
29
LLPS-Tar-0189
ENSTRUG00000010001.2
H2TKF9
LOC101062326
30
LLPS-Tar-1256
ENSTRUG00000023704.1
A0A3B5K5Z6
LOC101062657
31
LLPS-Tar-0687
ENSTRUG00000012893.2
H2U6U7
LOC101063194
32
LLPS-Tar-1108
ENSTRUG00000005266.2
H2SJP4
LOC101066426
33
LLPS-Tar-2644
ENSTRUG00000013707.2
A0A3B5JXV4
LOC101067757
34
LLPS-Tar-0591
ENSTRUG00000012449.2
H2U3M5
LOC101068853
35
LLPS-Tar-1919
ENSTRUG00000005131.2
H2SIR2
LOC101074742
36
LLPS-Tar-2778
ENSTRUG00000008435.2
A0A3B5JVE6
LOC101075759
37
LLPS-Tar-0190
ENSTRUG00000017978.2
H2VA29
LOC101076976
38
LLPS-Tar-0148
ENSTRUG00000020971.1
H2SNP7
LOC101077993
39
LLPS-Tar-3683
ENSTRUG00000010800.2
H2TRF6
LOC101079446
40
LLPS-Tar-1267
ENSTRUG00000024250.1
A0A3B5JVZ2
LOC101079607
41
LLPS-Tar-0118
ENSTRUG00000023965.1
A0A3B5K3T9
LOC105417833
42
LLPS-Tar-0618
ENSTRUG00000021242.1
H2RUY8
LOC105419818
43
LLPS-Tar-0049
ENSTRUG00000014269.2
H2UHR1
lyar
44
LLPS-Tar-0562
ENSTRUG00000008185.2
H2T744
ncl
45
LLPS-Tar-1459
ENSTRUG00000013932.2
H2UFB1
nedd1
46
LLPS-Tar-1585
ENSTRUG00000011577.2
H2TX53
pabpc1
47
LLPS-Tar-0216
ENSTRUG00000011419.2
H2TVY4
PCBP2 (1 of many)
48
LLPS-Tar-0480
ENSTRUG00000011149.2
H2TTX2
piwil1
49
LLPS-Tar-2111
ENSTRUG00000012599.2
H2U4N4
piwil2
50
LLPS-Tar-2178
ENSTRUG00000002165.2
H2RXU9
pmpcb
51
LLPS-Tar-3567
ENSTRUG00000024353.1
H2TKQ0
PSIP1
52
LLPS-Tar-1386
ENSTRUG00000013173.2
H2U993
rbm8a
53
LLPS-Tar-1124
ENSTRUG00000015498.2
H2URR8
rnf17
54
LLPS-Tar-2045
ENSTRUG00000020944.1
A0A3B5KKK2
rpl11
55
LLPS-Tar-0626
ENSTRUG00000017075.2
A0A3B5JY71
rpl23a
56
LLPS-Tar-2921
ENSTRUG00000012199.2
A0A3B5K9D4
rpl24
57
LLPS-Tar-0332
ENSTRUG00000007267.2
H2SZT8
rps8
58
LLPS-Tar-1852
ENSTRUG00000009037.2
H2TDI2
smg1
59
LLPS-Tar-2698
ENSTRUG00000000358.2
H2RL18
smg6
60
LLPS-Tar-1375
ENSTRUG00000003691.2
H2S8C5
srsf1
61
LLPS-Tar-3239
ENSTRUG00000012142.2
H2U1B9
tdrd1
62
LLPS-Tar-1774
ENSTRUG00000017194.2
H2V4B7
tdrd3
63
LLPS-Tar-1835
ENSTRUG00000001601.2
H2RU83
tdrd5
64
LLPS-Tar-2237
ENSTRUG00000009586.2
H2THD8
tdrd9
65
LLPS-Tar-1711
ENSTRUG00000012877.2
A0A3B5KNW9
tekt2
66
LLPS-Tar-3277
ENSTRUG00000006068.2
H2SQQ8
tekt4
67
LLPS-Tar-1950
ENSTRUG00000018491.2
H2VDP0
tnpo1
68
LLPS-Tar-2643
ENSTRUG00000009839.2
H2TJ69
tnrc6a
69
LLPS-Tar-0395
ENSTRUG00000015168.2
H2UP78
tra2b
70
LLPS-Tar-2220
ENSTRUG00000016316.2
H2UXP9
trpm5
71
LLPS-Tar-1370
ENSTRUG00000022232.1
A0A3B5JXT5
ubtd1
72
LLPS-Tar-0101
ENSTRUG00000011855.2
H2TZ48
vim
73
LLPS-Tar-2130
ENSTRUG00000001641.2
A0A3B5K327
vps26a
74
LLPS-Tar-0506
ENSTRUG00000001105.2
H2RR14
vps35
75
LLPS-Tar-3497
ENSTRUG00000011813.2
H2TYT1
YBX2
76
LLPS-Tar-3014
ENSTRUG00000006717.2
H2SVT0
YTHDC2