Taeniopygia guttata      Chromatoid body


※ Chromatoid body introduction

    A single large granule of nuage, presents in post-meiotic spermatids is called the chromatoid body (1). Multiple proteins and some mRNAs have been found to localized to the chromatoid body including mouse VASA homolog , tudor-domain containing 1 (TDRD1), tudor-domain containing 6 (TDRD6), and tudor-domain containing 7 (TDRD7) , transition protein 2 (Tnp2), RANBP9, as a known MVH interactor also localizes to it. Its formation is related to the coalescence of intermitochondrial cement granules. In fact, the formation of the chromatoid body is not required for microRNA biogenesis, but might be important for its action on target mRNAs (1). In mice, the chromatoid body is a structure resembles Gp, TDRD6 plays a role in establishing the body and the localization of piRNA pathway components to this body (2).

Reference
1. Woodruff, J. B., Hyman, A. A., & Boke, E. (2018) Organization and Function of Non-dynamic Biomolecular Condensates. Trends Biochem Sci, 43(2), 81-94. PMID: 30086300
2. Ma, L., Buchold, G. M., Greenbaum, M. P., Roy, A., Burns, K. H., Zhu, H., et al. (2009) GASZ is essential for male meiosis and suppression of retrotransposon expression in the male germline. PLoS Genet, 5(9), e1000635. PMID: 19730684


There are 80 genes.  Reviewed (0 or Unreviewed (80

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Tag-0059
ENSTGUG00000008696.1
H0ZEG3
2
LLPS-Tag-0552
ENSTGUG00000001085.1
H0YS67
3
LLPS-Tag-0650
ENSTGUG00000011267.1
H0ZLZ2
4
LLPS-Tag-0694
ENSTGUG00000014388.1
H0ZVY7
5
LLPS-Tag-1397
ENSTGUG00000004038.1
H0Z0S1
6
LLPS-Tag-1640
ENSTGUG00000009782.1
H0ZHN1
7
LLPS-Tag-1894
ENSTGUG00000017386.1
H1A450
8
LLPS-Tag-1948
ENSTGUG00000004520.1
H0Z258
9
LLPS-Tag-2386
ENSTGUG00000008416.1
H0ZDK5
10
LLPS-Tag-2538
ENSTGUG00000012887.1
H0ZRM7
11
LLPS-Tag-2565
ENSTGUG00000012119.1
H1A3P6
12
LLPS-Tag-3454
ENSTGUG00000006811.1
H0Z8V6
13
LLPS-Tag-3436
ENSTGUG00000010923.1
H0ZKY6
AFAP1L2
14
LLPS-Tag-0037
ENSTGUG00000012652.1
H0ZQY8
AGO2
15
LLPS-Tag-0768
ENSTGUG00000004962.1
H0Z3L0
ASZ1
16
LLPS-Tag-0086
ENSTGUG00000002300.1
H0YVQ2
CASC3
17
LLPS-Tag-2109
ENSTGUG00000000882.1
H0YRJ5
CD74
18
LLPS-Tag-1514
ENSTGUG00000004001.1
H0Z0M8
CNBP
19
LLPS-Tag-2443
ENSTGUG00000018747.1
Q27GW6
COX1
20
LLPS-Tag-0770
ENSTGUG00000013291.1
H0ZST9
CTSB
21
LLPS-Tag-0542
ENSTGUG00000002866.1
H0YXC4
CYCS
22
LLPS-Tag-0550
ENSTGUG00000006820.1
H0Z8X2
DCP1A
23
LLPS-Tag-0868
ENSTGUG00000013096.1
H0ZS97
DDX1
24
LLPS-Tag-2851
ENSTGUG00000000780.1
H0YR91
DDX25
25
LLPS-Tag-0347
ENSTGUG00000002548.1
H0YWF8
DDX4
26
LLPS-Tag-0043
ENSTGUG00000004622.1
H0Z2K1
DDX5
27
LLPS-Tag-0214
ENSTGUG00000012658.1
H0ZQZ5
DICER1
28
LLPS-Tag-0217
ENSTGUG00000005312.1
H0Z4J7
EDC4
29
LLPS-Tag-0475
ENSTGUG00000012670.1
H0ZR08
EEF1A1
30
LLPS-Tag-0829
ENSTGUG00000002132.1
H0YV83
EIF4A3
31
LLPS-Tag-0301
ENSTGUG00000003296.1
H0YYN4
EIF4E
32
LLPS-Tag-0842
ENSTGUG00000000118.1
H0YPC4
ELAVL1
33
LLPS-Tag-1971
ENSTGUG00000011042.1
H0ZLB1
ENO4
34
LLPS-Tag-1079
ENSTGUG00000010419.1
H0ZJJ7
EWSR1
35
LLPS-Tag-0517
ENSTGUG00000002869.1
H0YXD2
HNRNPA2B1
36
LLPS-Tag-0765
ENSTGUG00000002850.1
H0YXB3
HNRNPDL
37
LLPS-Tag-1255
ENSTGUG00000000938.1
H0YRQ7
HNRNPM
38
LLPS-Tag-0095
ENSTGUG00000008309.1
H0ZDE9
HNRNPU
39
LLPS-Tag-1289
ENSTGUG00000012808.1
H0ZRE5
HSP90AA1
40
LLPS-Tag-0566
ENSTGUG00000012929.1
H0ZRS0
HSPA2
41
LLPS-Tag-1796
ENSTGUG00000017346.1
H1A408
KHDRBS1
42
LLPS-Tag-3144
ENSTGUG00000009185.1
H0ZFX0
LAMP1
43
LLPS-Tag-1557
ENSTGUG00000008930.1
H0ZF34
LDHA
44
LLPS-Tag-1576
ENSTGUG00000009309.1
H0ZGB0
LOC100228204
45
LLPS-Tag-0586
ENSTGUG00000009916.1
H0ZI13
LYAR
46
LLPS-Tag-2202
ENSTGUG00000013511.1
H0ZTG5
MAEL
47
LLPS-Tag-0703
ENSTGUG00000012067.1
H0ZPA7
PABPC1
48
LLPS-Tag-0233
ENSTGUG00000004779.1
H0Z300
PIWIL1
49
LLPS-Tag-0699
ENSTGUG00000002778.1
H0YX43
PMPCB
50
LLPS-Tag-1138
ENSTGUG00000004519.1
H0Z283
PSIP1
51
LLPS-Tag-0334
ENSTGUG00000006110.1
H0Z6T7
RANBP9
52
LLPS-Tag-1020
ENSTGUG00000004447.1
B5FZD1
RBM8A
53
LLPS-Tag-0732
ENSTGUG00000001210.1
H0YSI9
RPL11
54
LLPS-Tag-0688
ENSTGUG00000006170.1
H0Z6Z7
RPL23A
55
LLPS-Tag-1266
ENSTGUG00000013618.1
H0ZTS6
RPL24
56
LLPS-Tag-1441
ENSTGUG00000018459.1
B5G2V9
RPS14
57
LLPS-Tag-1221
ENSTGUG00000007698.1
H0ZBH5
RPS8
58
LLPS-Tag-0523
ENSTGUG00000009449.1
H0ZGP2
SMG1
59
LLPS-Tag-1759
ENSTGUG00000005836.1
H0Z624
SMG6
60
LLPS-Tag-0487
ENSTGUG00000012308.1
H0ZPY7
SPERT
61
LLPS-Tag-1142
ENSTGUG00000000928.1
B5FY84
SRSF3
62
LLPS-Tag-3314
ENSTGUG00000010905.1
H0ZKY2
TDRD1
63
LLPS-Tag-2840
ENSTGUG00000012476.1
H0ZQF8
TDRD3
64
LLPS-Tag-2172
ENSTGUG00000013234.1
H0ZSM9
TDRD6
65
LLPS-Tag-1490
ENSTGUG00000001492.1
H0YTC8
TDRD7
66
LLPS-Tag-0112
ENSTGUG00000001625.1
H0YTR1
TEKT2
67
LLPS-Tag-3255
ENSTGUG00000006873.1
H0Z917
TEKT4
68
LLPS-Tag-2693
ENSTGUG00000006142.1
H0Z6Z4
TNRC6A
69
LLPS-Tag-1399
ENSTGUG00000005104.1
H0Z3W0
TOMM34
70
LLPS-Tag-1567
ENSTGUG00000008644.1
H0ZEB7
TOP3B
71
LLPS-Tag-1738
ENSTGUG00000006742.1
H0Z8P1
TRA2B
72
LLPS-Tag-2192
ENSTGUG00000009187.1
H0ZG25
TRPM5
73
LLPS-Tag-2462
ENSTGUG00000007307.1
H0ZAG4
TTC21B
74
LLPS-Tag-2531
ENSTGUG00000009637.1
H0ZH70
UBTD1
75
LLPS-Tag-2620
ENSTGUG00000001057.1
H0YS24
UPF1
76
LLPS-Tag-1063
ENSTGUG00000006522.1
H0Z892
USP9X
77
LLPS-Tag-0504
ENSTGUG00000001298.1
H0YST2
VIM
78
LLPS-Tag-2359
ENSTGUG00000003886.1
H0Z0C1
VPS26A
79
LLPS-Tag-2926
ENSTGUG00000008891.1
H0ZF25
VPS35
80
LLPS-Tag-1132
ENSTGUG00000003755.1
H0YZZ9
YTHDC2