Pongo abelii      Chromatoid body


※ Chromatoid body introduction

    A single large granule of nuage, presents in post-meiotic spermatids is called the chromatoid body (1). Multiple proteins and some mRNAs have been found to localized to the chromatoid body including mouse VASA homolog , tudor-domain containing 1 (TDRD1), tudor-domain containing 6 (TDRD6), and tudor-domain containing 7 (TDRD7) , transition protein 2 (Tnp2), RANBP9, as a known MVH interactor also localizes to it. Its formation is related to the coalescence of intermitochondrial cement granules. In fact, the formation of the chromatoid body is not required for microRNA biogenesis, but might be important for its action on target mRNAs (1). In mice, the chromatoid body is a structure resembles Gp, TDRD6 plays a role in establishing the body and the localization of piRNA pathway components to this body (2).

Reference
1. Woodruff, J. B., Hyman, A. A., & Boke, E. (2018) Organization and Function of Non-dynamic Biomolecular Condensates. Trends Biochem Sci, 43(2), 81-94. PMID: 30086300
2. Ma, L., Buchold, G. M., Greenbaum, M. P., Roy, A., Burns, K. H., Zhu, H., et al. (2009) GASZ is essential for male meiosis and suppression of retrotransposon expression in the male germline. PLoS Genet, 5(9), e1000635. PMID: 19730684


There are 94 genes.  Reviewed (0 or Unreviewed (94

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Poa-0026
ENSPPYG00000014944.2
H2PDY1
2
LLPS-Poa-0232
ENSPPYG00000000922.1
Q5RCS7
3
LLPS-Poa-0539
ENSPPYG00000012967.2
H2P7Y4
4
LLPS-Poa-1413
ENSPPYG00000016671.2
H2PJ91
5
LLPS-Poa-1872
ENSPPYG00000006180.1
H2NMD3
6
LLPS-Poa-2414
ENSPPYG00000006153.2
H2NMA4
7
LLPS-Poa-2988
ENSPPYG00000008015.2
H2NSU9
8
LLPS-Poa-3273
ENSPPYG00000007746.1
H2NS23
9
LLPS-Poa-3282
ENSPPYG00000002534.1
H2NB72
10
LLPS-Poa-3583
ENSPPYG00000003437.2
H2NDY3
11
LLPS-Poa-0555
ENSPPYG00000015042.1
H2PE88
ADAD1
12
LLPS-Poa-1574
ENSPPYG00000007601.1
H2NRM6
ADAD2
13
LLPS-Poa-4370
ENSPPYG00000002673.2
H2NBN9
AFAP1L2
14
LLPS-Poa-1605
ENSPPYG00000020351.1
H2PVN1
AKAP4
15
LLPS-Poa-1701
ENSPPYG00000017939.1
H2PNA8
ASZ1
16
LLPS-Poa-2192
ENSPPYG00000008467.1
H2NU84
CASC3
17
LLPS-Poa-2793
ENSPPYG00000013423.2
Q5R5R5
CNBP
18
LLPS-Poa-0655
ENSPPYG00000016548.2
H2PIV6
CR201_G0016348
19
LLPS-Poa-0251
ENSPPYG00000016655.2
A0A2J8Y4V1
CR201_G0016550
20
LLPS-Poa-0282
ENSPPYG00000018345.2
Q5R6D1
CTSB
21
LLPS-Poa-3172
ENSPPYG00000017719.2
Q5RFH4
CYCS
22
LLPS-Poa-0467
ENSPPYG00000013788.2
H2PAH6
DCP1A
23
LLPS-Poa-1938
ENSPPYG00000012638.2
A0A2J8V4C3
DDX1
24
LLPS-Poa-2546
ENSPPYG00000004041.2
H2NFT5
DDX25
25
LLPS-Poa-2415
ENSPPYG00000015472.2
H2PFK7
DDX4
26
LLPS-Poa-1446
ENSPPYG00000008547.2
A0A2J8UZV0
DDX5
27
LLPS-Poa-0848
ENSPPYG00000000431.2
Q5R874
DHX9
28
LLPS-Poa-0405
ENSPPYG00000006112.2
A0A2J8TLN5
DICER1
29
LLPS-Poa-2294
ENSPPYG00000015949.2
Q5RFJ4
DKFZp469K1522
30
LLPS-Poa-0565
ENSPPYG00000007473.2
H2NR94
EDC4
31
LLPS-Poa-1006
ENSPPYG00000007926.1
H2NSK2
EIF4A1
32
LLPS-Poa-2710
ENSPPYG00000008714.2
H2NUY8
EIF4A3
33
LLPS-Poa-0883
ENSPPYG00000009496.2
A0A2J8RD58
ELAVL1
34
LLPS-Poa-3137
ENSPPYG00000002686.2
H2NBQ7
ENO4
35
LLPS-Poa-2607
ENSPPYG00000011684.2
H2P3Y7
EWSR1
36
LLPS-Poa-4290
ENSPPYG00000018701.1
H2PQN3
FABP9
37
LLPS-Poa-3069
ENSPPYG00000013939.2
H2PAY5
FYCO1
38
LLPS-Poa-2176
ENSPPYG00000016292.1
H2PI42
HIST1H2BA
39
LLPS-Poa-1223
ENSPPYG00000017715.2
A0A2J8VDV7
HNRNPA2B1
40
LLPS-Poa-1405
ENSPPYG00000002212.1
A0A2J8XT95
HNRNPF
41
LLPS-Poa-0289
ENSPPYG00000009506.2
H2NXE4
HNRNPM
42
LLPS-Poa-2157
ENSPPYG00000000052.1
H2N383
HNRNPU
43
LLPS-Poa-0719
ENSPPYG00000016463.1
Q5R7D3
HSPA1
44
LLPS-Poa-1498
ENSPPYG00000005902.1
A0A2J8WLT7
HSPA2
45
LLPS-Poa-3485
ENSPPYG00000029648.1
K7EU70
ILF3
46
LLPS-Poa-2284
ENSPPYG00000013863.1
H2PAQ8
IP6K1
47
LLPS-Poa-0311
ENSPPYG00000001605.2
H2N863
KHDRBS1
48
LLPS-Poa-2867
ENSPPYG00000005524.1
H2NKD9
LAMP1
49
LLPS-Poa-4002
ENSPPYG00000019949.1
A0A2J8R7L3
LOC100439869
50
LLPS-Poa-0725
ENSPPYG00000016301.1
H2PI50
LOC100444716
51
LLPS-Poa-3334
ENSPPYG00000000555.2
A0A2J8SAL5
MAEL
52
LLPS-Poa-0863
ENSPPYG00000004277.1
H2NGJ3
MAGOHB
53
LLPS-Poa-2054
ENSPPYG00000020955.1
P92692
MT-CO1
54
LLPS-Poa-0594
ENSPPYG00000013265.2
H2P8W2
NCL
55
LLPS-Poa-0913
ENSPPYG00000004856.2
H2NIC1
NEDD1
56
LLPS-Poa-1744
ENSPPYG00000018799.1
H2PQY5
ODF1
57
LLPS-Poa-0944
ENSPPYG00000018790.1
A0A2J8UFH2
PABPC1
58
LLPS-Poa-2360
ENSPPYG00000005121.1
H2NJ51
PIWIL1
59
LLPS-Poa-0012
ENSPPYG00000018420.2
A0A2J8X4T6
PIWIL2
60
LLPS-Poa-1640
ENSPPYG00000017881.2
H2PN42
PMPCB
61
LLPS-Poa-1000
ENSPPYG00000019206.2
A0A2J8XI54
PSIP1
62
LLPS-Poa-3764
ENSPPYG00000007956.1
H2NSN3
RANGRF
63
LLPS-Poa-0905
ENSPPYG00000003015.1
H2NCQ6
RBM14
64
LLPS-Poa-2146
ENSPPYG00000000929.1
A0A2J8SQ68
RBM8A
65
LLPS-Poa-2028
ENSPPYG00000005577.1
H2NKI6
RNASE6
66
LLPS-Poa-3377
ENSPPYG00000005215.2
H2NJF0
RNF17
67
LLPS-Poa-0885
ENSPPYG00000001736.2
H2N8M1
RPL11
68
LLPS-Poa-1243
ENSPPYG00000008108.2
H2NT48
RPL23A
69
LLPS-Poa-0728
ENSPPYG00000013588.1
H2P9V3
RPL24
70
LLPS-Poa-1449
ENSPPYG00000015950.2
A0A2J8X626
RPS14
71
LLPS-Poa-0182
ENSPPYG00000001426.2
H2N7M3
RPS8
72
LLPS-Poa-0574
ENSPPYG00000007790.2
H2NS69
SMG6
73
LLPS-Poa-2310
ENSPPYG00000005342.1
H2NJT8
SPERT
74
LLPS-Poa-3274
ENSPPYG00000008240.2
K7EVN8
SRSF1
75
LLPS-Poa-2590
ENSPPYG00000017724.2
H2PMM6
STK31
76
LLPS-Poa-2431
ENSPPYG00000002671.2
H2NBN7
TDRD1
77
LLPS-Poa-1057
ENSPPYG00000005401.2
H2NK04
TDRD3
78
LLPS-Poa-2792
ENSPPYG00000000460.1
H2N4J0
TDRD5
79
LLPS-Poa-1276
ENSPPYG00000019423.2
H2PSU2
TDRD7
80
LLPS-Poa-4016
ENSPPYG00000001549.2
H2N804
TEKT2
81
LLPS-Poa-1093
ENSPPYG00000007100.2
H2NQ50
TNP2
82
LLPS-Poa-0371
ENSPPYG00000015545.2
H2PFU0
TNPO1
83
LLPS-Poa-4062
ENSPPYG00000007202.2
H2NQF8
TNRC6A
84
LLPS-Poa-3619
ENSPPYG00000011044.2
A4K2V0
TOMM34
85
LLPS-Poa-0172
ENSPPYG00000012014.2
A0A2J8RZC4
TOP3B
86
LLPS-Poa-1793
ENSPPYG00000014374.2
H2PC92
TRA2B
87
LLPS-Poa-0799
ENSPPYG00000002931.1
H2NCH0
TRPM5
88
LLPS-Poa-1514
ENSPPYG00000012897.2
H2P7P9
TTC21B
89
LLPS-Poa-0704
ENSPPYG00000007678.2
H2NRV0
TUBB3
90
LLPS-Poa-2700
ENSPPYG00000009752.2
H2NY45
UPF1
91
LLPS-Poa-3703
ENSPPYG00000020256.2
H2PVC1
USP9X
92
LLPS-Poa-3348
ENSPPYG00000002386.2
A0A2J8RN51
VPS26A
93
LLPS-Poa-3636
ENSPPYG00000007732.2
H2NS11
VPS35
94
LLPS-Poa-0337
ENSPPYG00000015691.2
H2PGA4
YTHDC2