Pelodiscus sinensis      Chromatoid body


※ Chromatoid body introduction

    A single large granule of nuage, presents in post-meiotic spermatids is called the chromatoid body (1). Multiple proteins and some mRNAs have been found to localized to the chromatoid body including mouse VASA homolog , tudor-domain containing 1 (TDRD1), tudor-domain containing 6 (TDRD6), and tudor-domain containing 7 (TDRD7) , transition protein 2 (Tnp2), RANBP9, as a known MVH interactor also localizes to it. Its formation is related to the coalescence of intermitochondrial cement granules. In fact, the formation of the chromatoid body is not required for microRNA biogenesis, but might be important for its action on target mRNAs (1). In mice, the chromatoid body is a structure resembles Gp, TDRD6 plays a role in establishing the body and the localization of piRNA pathway components to this body (2).

Reference
1. Woodruff, J. B., Hyman, A. A., & Boke, E. (2018) Organization and Function of Non-dynamic Biomolecular Condensates. Trends Biochem Sci, 43(2), 81-94. PMID: 30086300
2. Ma, L., Buchold, G. M., Greenbaum, M. P., Roy, A., Burns, K. H., Zhu, H., et al. (2009) GASZ is essential for male meiosis and suppression of retrotransposon expression in the male germline. PLoS Genet, 5(9), e1000635. PMID: 19730684


There are 81 genes.  Reviewed (0 or Unreviewed (81

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Pes-0032
ENSPSIG00000009556.1
K7FRC4
2
LLPS-Pes-0205
ENSPSIG00000007248.1
K7FK11
3
LLPS-Pes-0335
ENSPSIG00000005922.1
K7FEH1
4
LLPS-Pes-0353
ENSPSIG00000007037.1
K7FI08
5
LLPS-Pes-0421
ENSPSIG00000001495.1
K7F0E3
6
LLPS-Pes-0782
ENSPSIG00000002361.1
K7F2Y4
7
LLPS-Pes-0886
ENSPSIG00000009000.1
K7FPH3
8
LLPS-Pes-1043
ENSPSIG00000000167.1
K7EWK6
9
LLPS-Pes-1222
ENSPSIG00000006992.1
K7FI24
10
LLPS-Pes-1721
ENSPSIG00000017925.1
K7GIX0
11
LLPS-Pes-1750
ENSPSIG00000000397.1
K7GGP5
12
LLPS-Pes-2103
ENSPSIG00000004417.1
K7F9K8
13
LLPS-Pes-2415
ENSPSIG00000018106.1
K7GJI8
14
LLPS-Pes-3115
ENSPSIG00000005850.1
K7FEC8
15
LLPS-Pes-3206
ENSPSIG00000002868.1
K7F4K0
16
LLPS-Pes-3386
ENSPSIG00000014661.1
K7G853
17
LLPS-Pes-3441
ENSPSIG00000008725.1
K7FNI3
18
LLPS-Pes-3481
ENSPSIG00000013299.1
K7G3P3
19
LLPS-Pes-3551
ENSPSIG00000000031.1
K7EW71
20
LLPS-Pes-2210
ENSPSIG00000013429.1
K7G4B2
AFAP1L2
21
LLPS-Pes-2011
ENSPSIG00000013580.1
K7G4H5
AKAP4
22
LLPS-Pes-3280
ENSPSIG00000016815.1
K7GF67
ASZ1
23
LLPS-Pes-0233
ENSPSIG00000002339.1
K7F2V4
CASC3
24
LLPS-Pes-3563
ENSPSIG00000013807.1
K7G5D8
CD74
25
LLPS-Pes-2328
ENSPSIG00000003377.1
K7F689
CTSB
26
LLPS-Pes-1928
ENSPSIG00000003282.1
K7F5Y1
DCP1A
27
LLPS-Pes-2091
ENSPSIG00000012292.1
K7G071
DDX1
28
LLPS-Pes-2653
ENSPSIG00000012606.1
K7G1Y5
DDX25
29
LLPS-Pes-1855
ENSPSIG00000017179.1
K7GGN6
DDX4
30
LLPS-Pes-0919
ENSPSIG00000010830.1
K7FVN5
DDX5
31
LLPS-Pes-0818
ENSPSIG00000009211.1
K7FQ86
EDC4
32
LLPS-Pes-2941
ENSPSIG00000008719.1
K7FNH8
EIF4A1
33
LLPS-Pes-1854
ENSPSIG00000004036.1
K7F8C3
EIF4A3
34
LLPS-Pes-2102
ENSPSIG00000018060.1
K7GJE3
EIF4E
35
LLPS-Pes-2139
ENSPSIG00000013736.1
K7G535
ELAVL1
36
LLPS-Pes-2546
ENSPSIG00000013484.1
K7G447
ENO4
37
LLPS-Pes-2226
ENSPSIG00000004329.1
K7F9B6
EWSR1
38
LLPS-Pes-0944
ENSPSIG00000002659.1
K7F3X0
HNRNPA2B1
39
LLPS-Pes-0573
ENSPSIG00000016746.1
K7GF78
HNRNPDL
40
LLPS-Pes-0658
ENSPSIG00000011477.1
K7FXY3
HNRNPM
41
LLPS-Pes-2958
ENSPSIG00000005253.1
K7FCF6
HNRNPU
42
LLPS-Pes-1157
ENSPSIG00000001054.1
F5CI36
Hsp70
43
LLPS-Pes-0419
ENSPSIG00000017943.1
K7GJ25
HSP90AA1
44
LLPS-Pes-1314
ENSPSIG00000017706.1
K7GIC7
HSP90AB1
45
LLPS-Pes-0516
ENSPSIG00000008298.1
K7FM39
ILF3
46
LLPS-Pes-2026
ENSPSIG00000013720.1
K7G4X4
LAMP1
47
LLPS-Pes-1068
ENSPSIG00000002611.1
K7F3R3
LDHA
48
LLPS-Pes-0304
ENSPSIG00000015351.1
K7GAH9
LYAR
49
LLPS-Pes-1987
ENSPSIG00000009813.1
K7FSA6
MAEL
50
LLPS-Pes-1473
ENSPSIG00000019306.1
K7GK47
MT-CO1
51
LLPS-Pes-1672
ENSPSIG00000012665.1
K7G1P1
NEDD1
52
LLPS-Pes-0507
ENSPSIG00000003719.1
K7F7D2
PABPC1
53
LLPS-Pes-1416
ENSPSIG00000012190.1
K7FZV5
PMPCB
54
LLPS-Pes-2809
ENSPSIG00000018261.1
K7GK32
PSIP1
55
LLPS-Pes-2317
ENSPSIG00000009714.1
K7FRR0
RANBP9
56
LLPS-Pes-3077
ENSPSIG00000011245.1
K7FX61
RNF17
57
LLPS-Pes-1698
ENSPSIG00000008253.1
K7FMB2
RPL11
58
LLPS-Pes-1639
ENSPSIG00000005116.1
K7FBT2
RPL23A
59
LLPS-Pes-0828
ENSPSIG00000004065.1
K7F8G0
RPL24
60
LLPS-Pes-1038
ENSPSIG00000004543.1
K7FA12
SMG1
61
LLPS-Pes-0509
ENSPSIG00000006660.1
K7FGQ5
SMG6
62
LLPS-Pes-0226
ENSPSIG00000002526.1
K7F3G8
SRSF3
63
LLPS-Pes-3157
ENSPSIG00000015607.1
K7GBQ0
STK31
64
LLPS-Pes-2977
ENSPSIG00000014655.1
K7G882
TDRD1
65
LLPS-Pes-0846
ENSPSIG00000013821.1
K7G596
TDRD3
66
LLPS-Pes-0043
ENSPSIG00000010940.1
K7FVR3
TDRD5
67
LLPS-Pes-0714
ENSPSIG00000004747.1
K7FAR6
TDRD7
68
LLPS-Pes-0084
ENSPSIG00000010466.1
K7FUY3
TDRD9
69
LLPS-Pes-0138
ENSPSIG00000010645.1
K7FV05
TEKT2
70
LLPS-Pes-0146
ENSPSIG00000007983.1
K7FL69
TEKT4
71
LLPS-Pes-2989
ENSPSIG00000014366.1
K7G7M3
TNPO1
72
LLPS-Pes-2013
ENSPSIG00000015835.1
K7GCG7
TOP3B
73
LLPS-Pes-2147
ENSPSIG00000014097.1
K7G6A8
TRA2B
74
LLPS-Pes-0804
ENSPSIG00000009524.1
K7FS92
TRPM5
75
LLPS-Pes-3305
ENSPSIG00000011875.1
K7FZF7
TTC21B
76
LLPS-Pes-0120
ENSPSIG00000009491.1
K7FR01
UPF1
77
LLPS-Pes-1129
ENSPSIG00000016677.1
K7GF09
VIM
78
LLPS-Pes-1753
ENSPSIG00000017700.1
K7GI99
VPS26A
79
LLPS-Pes-3597
ENSPSIG00000014218.1
K7G6V6
VPS35
80
LLPS-Pes-3613
ENSPSIG00000012364.1
K7G0H9
YBX2
81
LLPS-Pes-0262
ENSPSIG00000014798.1
K7G944
YTHDC2