Otolemur garnettii      Chromatoid body


※ Chromatoid body introduction

    A single large granule of nuage, presents in post-meiotic spermatids is called the chromatoid body (1). Multiple proteins and some mRNAs have been found to localized to the chromatoid body including mouse VASA homolog , tudor-domain containing 1 (TDRD1), tudor-domain containing 6 (TDRD6), and tudor-domain containing 7 (TDRD7) , transition protein 2 (Tnp2), RANBP9, as a known MVH interactor also localizes to it. Its formation is related to the coalescence of intermitochondrial cement granules. In fact, the formation of the chromatoid body is not required for microRNA biogenesis, but might be important for its action on target mRNAs (1). In mice, the chromatoid body is a structure resembles Gp, TDRD6 plays a role in establishing the body and the localization of piRNA pathway components to this body (2).

Reference
1. Woodruff, J. B., Hyman, A. A., & Boke, E. (2018) Organization and Function of Non-dynamic Biomolecular Condensates. Trends Biochem Sci, 43(2), 81-94. PMID: 30086300
2. Ma, L., Buchold, G. M., Greenbaum, M. P., Roy, A., Burns, K. H., Zhu, H., et al. (2009) GASZ is essential for male meiosis and suppression of retrotransposon expression in the male germline. PLoS Genet, 5(9), e1000635. PMID: 19730684


There are 98 genes.  Reviewed (0 or Unreviewed (98

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Otg-0506
ENSOGAG00000000721.2
H0XXW2
2
LLPS-Otg-0512
ENSOGAG00000032833.1
H0XN74
3
LLPS-Otg-0599
ENSOGAG00000028793.1
H0XUE9
4
LLPS-Otg-1136
ENSOGAG00000031673.1
H0Y0V9
5
LLPS-Otg-1331
ENSOGAG00000025304.1
H0XUZ3
6
LLPS-Otg-1610
ENSOGAG00000034482.1
H0XMZ5
7
LLPS-Otg-2308
ENSOGAG00000024407.1
H0XT04
8
LLPS-Otg-2559
ENSOGAG00000026204.1
H0XXK4
9
LLPS-Otg-2884
ENSOGAG00000030527.1
H0XSN8
10
LLPS-Otg-3422
ENSOGAG00000030117.1
H0XNR5
11
LLPS-Otg-4435
ENSOGAG00000008455.2
H0WYI4
ADAD1
12
LLPS-Otg-2894
ENSOGAG00000009335.2
H0X0C9
ADAD2
13
LLPS-Otg-2585
ENSOGAG00000001373.2
H0WIG2
AFAP1L2
14
LLPS-Otg-0257
ENSOGAG00000007933.2
H0WXD0
AGO2
15
LLPS-Otg-3617
ENSOGAG00000029364.1
H0XSU2
AKAP4
16
LLPS-Otg-1162
ENSOGAG00000003040.2
H0WM03
ASZ1
17
LLPS-Otg-1181
ENSOGAG00000034486.1
H0XWE6
CASC3
18
LLPS-Otg-1963
ENSOGAG00000004628.2
H0WQB3
CD74
19
LLPS-Otg-2829
ENSOGAG00000015772.2
H0XDZ5
CTSB
20
LLPS-Otg-4495
ENSOGAG00000030025.1
G4XXS4
CYCS
21
LLPS-Otg-2353
ENSOGAG00000016915.2
H0XGE5
DCP1A
22
LLPS-Otg-2972
ENSOGAG00000008730.2
H0WZ41
DDX1
23
LLPS-Otg-2091
ENSOGAG00000013409.2
H0X915
DDX25
24
LLPS-Otg-1182
ENSOGAG00000007588.2
H0WWM5
DDX4
25
LLPS-Otg-1352
ENSOGAG00000002620.2
H0WL47
DHX9
26
LLPS-Otg-3060
ENSOGAG00000010719.2
H0X3B0
DICER1
27
LLPS-Otg-1872
ENSOGAG00000015571.2
H0XDK6
EDC4
28
LLPS-Otg-0740
ENSOGAG00000008132.2
H0WXS7
EIF4A1
29
LLPS-Otg-2023
ENSOGAG00000007495.2
H0WWF0
EIF4A3
30
LLPS-Otg-2008
ENSOGAG00000012877.1
H0X7X4
ELAVL1
31
LLPS-Otg-3025
ENSOGAG00000003444.2
H0WMS8
ENO4
32
LLPS-Otg-2864
ENSOGAG00000012489.2
H0X716
EWSR1
33
LLPS-Otg-3578
ENSOGAG00000012168.2
H0X6B7
FABP9
34
LLPS-Otg-0567
ENSOGAG00000003819.2
H0WNJ1
FYCO1
35
LLPS-Otg-0117
ENSOGAG00000024612.1
H0XNU2
HIST1H2BA
36
LLPS-Otg-2199
ENSOGAG00000015353.2
H0XD32
HNRNPA2B1
37
LLPS-Otg-2824
ENSOGAG00000028132.1
H0XLZ3
HNRNPA3
38
LLPS-Otg-1053
ENSOGAG00000002501.2
H0WKV3
HNRNPDL
39
LLPS-Otg-2300
ENSOGAG00000012631.2
H0X7D4
HNRNPH1
40
LLPS-Otg-2248
ENSOGAG00000030987.1
H0XK69
HNRNPM
41
LLPS-Otg-2613
ENSOGAG00000014024.2
H0XAC3
HNRNPU
42
LLPS-Otg-1122
ENSOGAG00000017159.2
H0XGZ3
IGF2BP3
43
LLPS-Otg-4558
ENSOGAG00000011807.2
H0X5J8
IP6K1
44
LLPS-Otg-1112
ENSOGAG00000004582.2
H0WQ76
KHDRBS1
45
LLPS-Otg-2520
ENSOGAG00000009899.2
H0X1H9
LAMP1
46
LLPS-Otg-3164
ENSOGAG00000028965.1
H0XKG8
LOC100944465
47
LLPS-Otg-1512
ENSOGAG00000028084.1
H0XP97
LOC100956985
48
LLPS-Otg-2414
ENSOGAG00000013734.2
H0X9P8
LOC100964496
49
LLPS-Otg-0780
ENSOGAG00000033115.1
H0XSQ7
LOC100966393
50
LLPS-Otg-0868
ENSOGAG00000006003.1
H0WXG7
LOC111724948
51
LLPS-Otg-0041
ENSOGAG00000007993.1
H0XJY6
LOC111724950
52
LLPS-Otg-1936
ENSOGAG00000007627.2
H0WWQ3
MAEL
53
LLPS-Otg-1317
ENSOGAG00000005824.2
H0WSX4
NEDD1
54
LLPS-Otg-2621
ENSOGAG00000014525.2
H0XBD7
ODF1
55
LLPS-Otg-0177
ENSOGAG00000028946.1
H0XQQ0
PCBP1
56
LLPS-Otg-0012
ENSOGAG00000015400.2
H0XD65
PIWIL1
57
LLPS-Otg-1560
ENSOGAG00000004913.2
H0WQX2
PIWIL2
58
LLPS-Otg-0943
ENSOGAG00000005156.2
H0WRF9
PMPCB
59
LLPS-Otg-2600
ENSOGAG00000002179.2
H0WK77
PSIP1
60
LLPS-Otg-2215
ENSOGAG00000013455.2
H0X944
RANBP9
61
LLPS-Otg-3038
ENSOGAG00000016343.2
H0XF56
RANGRF
62
LLPS-Otg-1861
ENSOGAG00000032829.1
H0XXZ5
RBM14
63
LLPS-Otg-1332
ENSOGAG00000000202.2
H0WFY0
RBM8A
64
LLPS-Otg-2303
ENSOGAG00000007769.2
H0WX03
RNASE6
65
LLPS-Otg-3092
ENSOGAG00000014803.2
H0XC03
RNF17
66
LLPS-Otg-1825
ENSOGAG00000032741.1
H0XJD6
RPL11
67
LLPS-Otg-0389
ENSOGAG00000013843.2
H0X9X5
RPL24
68
LLPS-Otg-1679
ENSOGAG00000006922.2
H0WV78
RPS8
69
LLPS-Otg-2569
ENSOGAG00000013206.2
H0X8L7
SMG1
70
LLPS-Otg-2937
ENSOGAG00000004483.2
H0WQ01
SMG6
71
LLPS-Otg-1074
ENSOGAG00000029836.1
H0XJD7
SPERT
72
LLPS-Otg-3359
ENSOGAG00000025950.1
H0XX12
SRSF1
73
LLPS-Otg-0530
ENSOGAG00000000502.2
H0WGJ8
SRSF3
74
LLPS-Otg-3557
ENSOGAG00000013559.2
H0X9D1
STK31
75
LLPS-Otg-3482
ENSOGAG00000001370.2
H0WIG0
TDRD1
76
LLPS-Otg-1602
ENSOGAG00000005898.2
H0WT25
TDRD3
77
LLPS-Otg-0916
ENSOGAG00000008026.2
H0WXJ6
TDRD5
78
LLPS-Otg-0921
ENSOGAG00000000404.2
H0WGC2
TDRD6
79
LLPS-Otg-0075
ENSOGAG00000009556.2
H0X0T2
TDRD7
80
LLPS-Otg-0424
ENSOGAG00000007626.2
H0WWQ2
TDRD9
81
LLPS-Otg-2834
ENSOGAG00000032145.1
H0XMC7
TEKT2
82
LLPS-Otg-0316
ENSOGAG00000025332.1
H0XKX4
TEKT4
83
LLPS-Otg-0039
ENSOGAG00000014858.2
H0XWF1
TNP2
84
LLPS-Otg-1123
ENSOGAG00000000808.2
H0WH89
TNPO1
85
LLPS-Otg-1101
ENSOGAG00000006666.2
H0WUN8
TNRC6A
86
LLPS-Otg-2113
ENSOGAG00000008911.2
H0WZH1
TOMM34
87
LLPS-Otg-1543
ENSOGAG00000017236.2
H0XH52
TOP3B
88
LLPS-Otg-2985
ENSOGAG00000005386.2
H0WRY6
TRA2B
89
LLPS-Otg-2284
ENSOGAG00000015780.2
H0XE03
TRPM5
90
LLPS-Otg-1926
ENSOGAG00000016385.2
H0XF97
TTC21B
91
LLPS-Otg-4351
ENSOGAG00000008777.2
H0WZ75
UBTD1
92
LLPS-Otg-1735
ENSOGAG00000012866.2
H0X7W8
UPF1
93
LLPS-Otg-2287
ENSOGAG00000027364.1
H0XNE3
USP9X
94
LLPS-Otg-0016
ENSOGAG00000006667.2
H0WUN5
VIM
95
LLPS-Otg-2639
ENSOGAG00000005911.2
H0WT35
VPS26A
96
LLPS-Otg-4219
ENSOGAG00000000396.2
H0WGB6
VPS35
97
LLPS-Otg-0300
ENSOGAG00000004392.2
H0WPT4
YBX2
98
LLPS-Otg-1195
ENSOGAG00000001618.2
H0WJ02
YTHDC2