Oryctolagus cuniculus      Chromatoid body


※ Chromatoid body introduction

    A single large granule of nuage, presents in post-meiotic spermatids is called the chromatoid body (1). Multiple proteins and some mRNAs have been found to localized to the chromatoid body including mouse VASA homolog , tudor-domain containing 1 (TDRD1), tudor-domain containing 6 (TDRD6), and tudor-domain containing 7 (TDRD7) , transition protein 2 (Tnp2), RANBP9, as a known MVH interactor also localizes to it. Its formation is related to the coalescence of intermitochondrial cement granules. In fact, the formation of the chromatoid body is not required for microRNA biogenesis, but might be important for its action on target mRNAs (1). In mice, the chromatoid body is a structure resembles Gp, TDRD6 plays a role in establishing the body and the localization of piRNA pathway components to this body (2).

Reference
1. Woodruff, J. B., Hyman, A. A., & Boke, E. (2018) Organization and Function of Non-dynamic Biomolecular Condensates. Trends Biochem Sci, 43(2), 81-94. PMID: 30086300
2. Ma, L., Buchold, G. M., Greenbaum, M. P., Roy, A., Burns, K. H., Zhu, H., et al. (2009) GASZ is essential for male meiosis and suppression of retrotransposon expression in the male germline. PLoS Genet, 5(9), e1000635. PMID: 19730684


There are 99 genes.  Reviewed (0 or Unreviewed (99

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Orc-0467
ENSOCUG00000017172.2
G1TN68
2
LLPS-Orc-0609
ENSOCUG00000001280.3
A0A0G2JH20
3
LLPS-Orc-1376
ENSOCUG00000004432.3
G1SLT2
4
LLPS-Orc-2452
ENSOCUG00000027557.1
G1U5S4
5
LLPS-Orc-3367
ENSOCUG00000026992.1
G1U6W1
6
LLPS-Orc-3425
ENSOCUG00000023204.1
G1U695
7
LLPS-Orc-4097
ENSOCUG00000012989.3
G1T4H2
ADAD1
8
LLPS-Orc-0637
ENSOCUG00000024782.2
G1TPA0
ADAD2
9
LLPS-Orc-2779
ENSOCUG00000011712.2
G1T1U0
AFAP1L2
10
LLPS-Orc-3769
ENSOCUG00000015962.3
Q09YN0
ASZ1
11
LLPS-Orc-1516
ENSOCUG00000002954.3
G1TNQ2
CASC3
12
LLPS-Orc-2643
ENSOCUG00000003863.3
G1SKK3
CD74
13
LLPS-Orc-1005
ENSOCUG00000010483.3
G1U0Z7
CENPV
14
LLPS-Orc-1470
ENSOCUG00000008696.2
G1TUC2
CNBP
15
LLPS-Orc-3213
ENSOCUG00000016580.3
G1TBY1
CTSB
16
LLPS-Orc-2062
ENSOCUG00000011971.3
G1T2C7
DCP1A
17
LLPS-Orc-0529
ENSOCUG00000007010.3
G1SS73
DDX1
18
LLPS-Orc-0070
ENSOCUG00000004476.2
G1SLW4
DDX25
19
LLPS-Orc-1214
ENSOCUG00000008597.3
G1SVI0
DDX4
20
LLPS-Orc-0988
ENSOCUG00000026305.2
G1TLW3
DDX5
21
LLPS-Orc-0551
ENSOCUG00000014651.3
G1TGK9
DHX9
22
LLPS-Orc-2837
ENSOCUG00000010849.3
G1T047
DICER1
23
LLPS-Orc-2734
ENSOCUG00000006327.3
G1SQT2
EDC4
24
LLPS-Orc-1196
ENSOCUG00000010375.2
G1SZ59
EIF4A1
25
LLPS-Orc-1232
ENSOCUG00000001456.3
A0A0A0MQQ6
EIF4E
26
LLPS-Orc-2010
ENSOCUG00000015871.3
G1TAE2
ELAVL1
27
LLPS-Orc-2666
ENSOCUG00000008897.3
G1SW39
ENO4
28
LLPS-Orc-3847
ENSOCUG00000007448.2
G1ST29
FABP9
29
LLPS-Orc-3329
ENSOCUG00000004305.3
G1SLI7
FYCO1
30
LLPS-Orc-1100
ENSOCUG00000026859.1
G1TWL0
HNRNPA2B1
31
LLPS-Orc-3996
ENSOCUG00000002743.3
G1SI79
HNRNPA3
32
LLPS-Orc-0294
ENSOCUG00000013805.2
G1T657
HNRNPDL
33
LLPS-Orc-2240
ENSOCUG00000024719.1
G1TMU2
HNRNPF
34
LLPS-Orc-1765
ENSOCUG00000017150.3
G1U248
HNRNPH1
35
LLPS-Orc-0033
ENSOCUG00000014469.3
G1T7H0
HNRNPU
36
LLPS-Orc-3389
ENSOCUG00000012842.3
P30947
HSP90AB1
37
LLPS-Orc-1052
ENSOCUG00000011745.1
G1T1V9
HSPA2
38
LLPS-Orc-1391
ENSOCUG00000008976.3
G1SWA1
IGF2BP3
39
LLPS-Orc-2055
ENSOCUG00000013990.3
G1T6I6
ILF3
40
LLPS-Orc-2765
ENSOCUG00000005017.2
G1TQD6
IP6K1
41
LLPS-Orc-2262
ENSOCUG00000007654.3
G1STI3
KHDRBS1
42
LLPS-Orc-3150
ENSOCUG00000022480.2
G1TRZ2
LAMP1
43
LLPS-Orc-1535
ENSOCUG00000015939.2
G1TX67
LDHA
44
LLPS-Orc-3262
ENSOCUG00000014459.2
G1TWR1
LOC100347279
45
LLPS-Orc-3911
ENSOCUG00000022998.2
G1U031
LOC100349209
46
LLPS-Orc-3782
ENSOCUG00000027410.1
G1T8N1
LOC100350750
47
LLPS-Orc-0086
ENSOCUG00000017511.2
G1TJW1
LOC100352057
48
LLPS-Orc-1919
ENSOCUG00000025112.1
G1TRC0
LOC100354037
49
LLPS-Orc-3384
ENSOCUG00000025605.1
G1U0B4
LOC100357329
50
LLPS-Orc-2658
ENSOCUG00000000851.2
G1SE76
LOC108177184
51
LLPS-Orc-0356
ENSOCUG00000002386.2
G1SHF7
LYAR
52
LLPS-Orc-0082
ENSOCUG00000005848.3
G1SPT1
MAEL
53
LLPS-Orc-2284
ENSOCUG00000029403.1
U3KND8
MAGOHB
54
LLPS-Orc-0500
ENSOCUG00000029096.1
O79429
MT-CO1
55
LLPS-Orc-0396
ENSOCUG00000004312.2
G1TVT0
NCL
56
LLPS-Orc-1038
ENSOCUG00000010944.3
G1T0B2
NEDD1
57
LLPS-Orc-0243
ENSOCUG00000017222.3
G1TD87
ODF1
58
LLPS-Orc-0006
ENSOCUG00000004354.2
G1SLM0
PABPC1
59
LLPS-Orc-2093
ENSOCUG00000003634.2
O19048
PCBP1
60
LLPS-Orc-3664
ENSOCUG00000022490.1
G1U2V6
PCBP2
61
LLPS-Orc-0989
ENSOCUG00000027444.2
G1TP64
PIWIL1
62
LLPS-Orc-1686
ENSOCUG00000006261.3
G1SQN1
PIWIL2
63
LLPS-Orc-1029
ENSOCUG00000010200.3
G1SYT7
PMPCB
64
LLPS-Orc-3886
ENSOCUG00000009319.3
G1SX00
PSIP1
65
LLPS-Orc-1583
ENSOCUG00000007255.3
G1SSN9
RANBP9
66
LLPS-Orc-1837
ENSOCUG00000023954.1
G1TUY4
RANGRF
67
LLPS-Orc-1844
ENSOCUG00000022838.1
G1TRT5
RBM14
68
LLPS-Orc-1944
ENSOCUG00000025693.1
G1TX03
RBM8A
69
LLPS-Orc-4045
ENSOCUG00000007494.1
G1ST62
RNASE6
70
LLPS-Orc-0224
ENSOCUG00000007384.3
G1SSY9
RNF17
71
LLPS-Orc-0671
ENSOCUG00000022928.2
G1TUB8
RPL11
72
LLPS-Orc-1494
ENSOCUG00000000791.2
G1SE28
RPL24
73
LLPS-Orc-1015
ENSOCUG00000011509.2
G1T1F0
RPS14
74
LLPS-Orc-1801
ENSOCUG00000016615.3
G1TC15
SMG1
75
LLPS-Orc-0401
ENSOCUG00000013018.3
G1T4K3
SMG6
76
LLPS-Orc-1203
ENSOCUG00000014037.3
G1T6L4
SPERT
77
LLPS-Orc-0704
ENSOCUG00000017678.3
G1TE69
SRSF1
78
LLPS-Orc-2381
ENSOCUG00000006684.3
G1SRH7
SRSF3
79
LLPS-Orc-3681
ENSOCUG00000004738.3
G1SMF1
STK31
80
LLPS-Orc-0526
ENSOCUG00000025327.2
G1THQ9
TDRD1
81
LLPS-Orc-1649
ENSOCUG00000014261.3
G1T721
TDRD3
82
LLPS-Orc-1218
ENSOCUG00000000491.3
G1U5T2
TDRD5
83
LLPS-Orc-2578
ENSOCUG00000000760.3
G1SE04
TDRD6
84
LLPS-Orc-0324
ENSOCUG00000000060.2
G1SCH8
TDRD7
85
LLPS-Orc-2375
ENSOCUG00000029722.1
G1T0G8
TEKT2
86
LLPS-Orc-0533
ENSOCUG00000021104.2
G1U6B0
TNP2
87
LLPS-Orc-0437
ENSOCUG00000013318.3
G1T568
TNPO1
88
LLPS-Orc-3876
ENSOCUG00000004325.3
G1SLK0
TNRC6A
89
LLPS-Orc-3942
ENSOCUG00000003012.3
G1SIU6
TOMM34
90
LLPS-Orc-1956
ENSOCUG00000012288.3
G1T303
TOP3B
91
LLPS-Orc-1823
ENSOCUG00000008940.3
G1U9B4
TRA2B
92
LLPS-Orc-3037
ENSOCUG00000010620.3
G1SZP1
TTC21B
93
LLPS-Orc-1702
ENSOCUG00000007789.3
G1STS8
UBTD1
94
LLPS-Orc-3448
ENSOCUG00000007198.3
G1TEW4
USP9X
95
LLPS-Orc-0256
ENSOCUG00000009222.3
G1SWS9
VIM
96
LLPS-Orc-1241
ENSOCUG00000001513.3
G1TM00
VPS26A
97
LLPS-Orc-3692
ENSOCUG00000010484.2
G1SZE0
VPS35
98
LLPS-Orc-4027
ENSOCUG00000015064.2
G1T8N6
YBX2
99
LLPS-Orc-0916
ENSOCUG00000012096.3
G1T2M1
YTHDC2