Nomascus leucogenys      Chromatoid body


※ Chromatoid body introduction

    A single large granule of nuage, presents in post-meiotic spermatids is called the chromatoid body (1). Multiple proteins and some mRNAs have been found to localized to the chromatoid body including mouse VASA homolog , tudor-domain containing 1 (TDRD1), tudor-domain containing 6 (TDRD6), and tudor-domain containing 7 (TDRD7) , transition protein 2 (Tnp2), RANBP9, as a known MVH interactor also localizes to it. Its formation is related to the coalescence of intermitochondrial cement granules. In fact, the formation of the chromatoid body is not required for microRNA biogenesis, but might be important for its action on target mRNAs (1). In mice, the chromatoid body is a structure resembles Gp, TDRD6 plays a role in establishing the body and the localization of piRNA pathway components to this body (2).

Reference
1. Woodruff, J. B., Hyman, A. A., & Boke, E. (2018) Organization and Function of Non-dynamic Biomolecular Condensates. Trends Biochem Sci, 43(2), 81-94. PMID: 30086300
2. Ma, L., Buchold, G. M., Greenbaum, M. P., Roy, A., Burns, K. H., Zhu, H., et al. (2009) GASZ is essential for male meiosis and suppression of retrotransposon expression in the male germline. PLoS Genet, 5(9), e1000635. PMID: 19730684


There are 101 genes.  Reviewed (0 or Unreviewed (101

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Nol-1419
ENSNLEG00000001884.2
G1QMU0
2
LLPS-Nol-2361
ENSNLEG00000033915.1
A0A2I3FR46
3
LLPS-Nol-2718
ENSNLEG00000010858.2
A0A2I3G3E7
4
LLPS-Nol-4473
ENSNLEG00000009415.2
G1RE24
ADAD1
5
LLPS-Nol-1150
ENSNLEG00000011048.3
A0A2I3GNC7
ADAD2
6
LLPS-Nol-3221
ENSNLEG00000016245.3
G1S2K0
AFAP1L2
7
LLPS-Nol-0239
ENSNLEG00000001461.3
G1QLE6
AGO2
8
LLPS-Nol-2435
ENSNLEG00000008132.2
G1R9M2
AKAP4
9
LLPS-Nol-1158
ENSNLEG00000011649.2
Q07DX6
ASZ1
10
LLPS-Nol-4198
ENSNLEG00000001598.3
G1QM47
CASC3
11
LLPS-Nol-1935
ENSNLEG00000010343.3
G1RHB8
CD74
12
LLPS-Nol-0518
ENSNLEG00000035879.1
A0A2I3GB54
CNBP
13
LLPS-Nol-2587
ENSNLEG00000015086.3
G1RYK8
CTSB
14
LLPS-Nol-1206
ENSNLEG00000007219.3
G1R6I4
DCP1A
15
LLPS-Nol-2296
ENSNLEG00000014417.3
A0A2I3HKV9
DDX1
16
LLPS-Nol-4078
ENSNLEG00000007461.2
G1R7B0
DDX25
17
LLPS-Nol-2346
ENSNLEG00000001662.3
G1QMZ9
DDX4
18
LLPS-Nol-2345
ENSNLEG00000014929.2
A0A2I3HLE2
DDX5
19
LLPS-Nol-0744
ENSNLEG00000018013.2
G1S8P5
DHX9
20
LLPS-Nol-0703
ENSNLEG00000017309.3
G1S694
DICER1
21
LLPS-Nol-2478
ENSNLEG00000004932.3
G1QYN1
EDC4
22
LLPS-Nol-0265
ENSNLEG00000035164.1
A0A2I3HHP9
EEF1A1
23
LLPS-Nol-1020
ENSNLEG00000009547.2
G1RER5
EIF4A1
24
LLPS-Nol-2282
ENSNLEG00000014006.3
G1RUR6
EIF4E
25
LLPS-Nol-0449
ENSNLEG00000001325.2
G1QKW5
ELAVL1
26
LLPS-Nol-1771
ENSNLEG00000016516.2
A0A2I3GHV1
ENO4
27
LLPS-Nol-3433
ENSNLEG00000002641.3
G1QR82
EWSR1
28
LLPS-Nol-3950
ENSNLEG00000002486.2
G1QPZ3
FABP9
29
LLPS-Nol-4293
ENSNLEG00000006092.2
G1R2H8
FYCO1
30
LLPS-Nol-2557
ENSNLEG00000001234.2
G1QKS7
GPX4
31
LLPS-Nol-0002
ENSNLEG00000028902.1
G1SAW5
HIST1H3G
32
LLPS-Nol-1078
ENSNLEG00000027152.1
G1SAW1
HIST1H4A
33
LLPS-Nol-2764
ENSNLEG00000014918.3
G1RY30
HNRNPA2B1
34
LLPS-Nol-2668
ENSNLEG00000008636.2
G1RBI6
HNRNPDL
35
LLPS-Nol-0671
ENSNLEG00000019098.2
G1SBQ3
HNRNPF
36
LLPS-Nol-0441
ENSNLEG00000026658.2
A0A2I3HQA4
HNRNPH1
37
LLPS-Nol-1748
ENSNLEG00000004046.3
A0A2I3HDL0
HNRNPU
38
LLPS-Nol-0219
ENSNLEG00000015925.3
A0A2I3FZX2
HSP90AA1
39
LLPS-Nol-2636
ENSNLEG00000029372.1
A0A2I3G8H3
HSP90AB1
40
LLPS-Nol-0893
ENSNLEG00000019134.2
G1SBT8
HSPA2
41
LLPS-Nol-0298
ENSNLEG00000014780.2
G1RXK8
IGF2BP3
42
LLPS-Nol-2510
ENSNLEG00000012290.2
G1RP09
ILF3
43
LLPS-Nol-0083
ENSNLEG00000006900.3
G1R5D4
IP6K1
44
LLPS-Nol-3460
ENSNLEG00000000749.3
A0A2I3G2X9
LAMP1
45
LLPS-Nol-0006
ENSNLEG00000030432.1
A0A2I3HFC4
LDHA
46
LLPS-Nol-3908
ENSNLEG00000014901.2
G1RY04
LOC100580069
47
LLPS-Nol-4529
ENSNLEG00000015940.2
G1S1K0
LOC100581245
48
LLPS-Nol-2673
ENSNLEG00000026840.2
M3ZBN8
LOC100587604
49
LLPS-Nol-3720
ENSNLEG00000010366.3
G1S9K8
LOC101177997
50
LLPS-Nol-3845
ENSNLEG00000028329.1
A0A2I3GTA1
LOC105740194
51
LLPS-Nol-2094
ENSNLEG00000016149.3
G1S257
LYAR
52
LLPS-Nol-2387
ENSNLEG00000014771.2
G1RXJ4
MAEL
53
LLPS-Nol-0503
ENSNLEG00000003355.2
G1QT10
MAGOHB
54
LLPS-Nol-0764
ENSNLEG00000014107.3
G1RV70
NCL
55
LLPS-Nol-4289
ENSNLEG00000005930.2
G1R1Y5
NEDD1
56
LLPS-Nol-2726
ENSNLEG00000003644.2
G1QTW7
ODF1
57
LLPS-Nol-1581
ENSNLEG00000003142.3
A0A2I3GLQ4
PABPC1
58
LLPS-Nol-0187
ENSNLEG00000018722.2
G1SAQ4
PCBP1
59
LLPS-Nol-1664
ENSNLEG00000017693.3
A0A2I3GFQ2
PCBP2
60
LLPS-Nol-0525
ENSNLEG00000008225.2
G1RA00
PIWIL1
61
LLPS-Nol-3543
ENSNLEG00000015534.3
G1S033
PIWIL2
62
LLPS-Nol-0142
ENSNLEG00000009342.2
G1RDW6
PMPCB
63
LLPS-Nol-3049
ENSNLEG00000017585.3
G1S757
PSIP1
64
LLPS-Nol-0283
ENSNLEG00000000899.2
G1QJH0
RANBP9
65
LLPS-Nol-4316
ENSNLEG00000027240.1
A0A2I3GLJ3
RANGRF
66
LLPS-Nol-1394
ENSNLEG00000029632.1
A0A2I3I026
RBM8A
67
LLPS-Nol-1551
ENSNLEG00000007523.2
G1R7H4
RNASE6
68
LLPS-Nol-3770
ENSNLEG00000013780.2
G1RUB4
RNF17
69
LLPS-Nol-2244
ENSNLEG00000028203.1
A0A2I3GLZ6
RPL11
70
LLPS-Nol-4152
ENSNLEG00000002872.2
G1QRB7
RPL23A
71
LLPS-Nol-1918
ENSNLEG00000003276.2
A0A2I3H3Q6
RPL24
72
LLPS-Nol-1071
ENSNLEG00000014147.3
G1RVA5
RPS8
73
LLPS-Nol-4098
ENSNLEG00000005445.3
G1R0C7
SMG1
74
LLPS-Nol-2485
ENSNLEG00000017171.3
G1S5T4
SMG6
75
LLPS-Nol-2819
ENSNLEG00000002469.2
G1QPY4
SPERT
76
LLPS-Nol-0452
ENSNLEG00000008088.3
G1R9I1
SRSF1
77
LLPS-Nol-1363
ENSNLEG00000010737.3
A0A2I3HJC3
SRSF3
78
LLPS-Nol-1623
ENSNLEG00000014801.2
A0A2I3HQE5
STK31
79
LLPS-Nol-2931
ENSNLEG00000016228.2
G1S2F6
TDRD1
80
LLPS-Nol-1727
ENSNLEG00000015920.3
A0A2I3GC30
TDRD3
81
LLPS-Nol-3612
ENSNLEG00000015751.3
G1S0W5
TDRD5
82
LLPS-Nol-0826
ENSNLEG00000004513.3
G1QWY6
TDRD6
83
LLPS-Nol-2805
ENSNLEG00000016885.2
G1S4T3
TDRD7
84
LLPS-Nol-2791
ENSNLEG00000016251.2
G1S2J9
TDRD9
85
LLPS-Nol-0766
ENSNLEG00000011235.3
G1RKB9
TEKT2
86
LLPS-Nol-1681
ENSNLEG00000016708.2
G1S447
TEKT4
87
LLPS-Nol-1332
ENSNLEG00000018453.2
G1SA05
TNP2
88
LLPS-Nol-0455
ENSNLEG00000004572.2
A0A2I3H5T5
TNPO1
89
LLPS-Nol-2354
ENSNLEG00000011851.3
G1RMH2
TNRC6A
90
LLPS-Nol-0584
ENSNLEG00000006657.2
G1R4I3
TOMM34
91
LLPS-Nol-2076
ENSNLEG00000000270.3
G1QHD0
TOP3B
92
LLPS-Nol-3504
ENSNLEG00000035272.1
A0A2I3G2U7
TRA2B
93
LLPS-Nol-0666
ENSNLEG00000002736.2
G1QQT5
TRPM5
94
LLPS-Nol-4400
ENSNLEG00000003246.3
G1QSN7
TTC21B
95
LLPS-Nol-0071
ENSNLEG00000014204.3
G1RVH1
UBTD1
96
LLPS-Nol-2048
ENSNLEG00000006062.2
A0A2I3HDQ5
UPF1
97
LLPS-Nol-4646
ENSNLEG00000001837.3
A0A2I3FXJ4
USP9X
98
LLPS-Nol-3490
ENSNLEG00000011548.3
A0A2I3FSA1
VPS26A
99
LLPS-Nol-3685
ENSNLEG00000015584.3
G1S0E8
VPS35
100
LLPS-Nol-4020
ENSNLEG00000008063.3
G1R9E5
YBX2
101
LLPS-Nol-3808
ENSNLEG00000011648.2
G1RLV7
YTHDC2