Mandrillus leucophaeus      Chromatoid body


※ Chromatoid body introduction

    A single large granule of nuage, presents in post-meiotic spermatids is called the chromatoid body (1). Multiple proteins and some mRNAs have been found to localized to the chromatoid body including mouse VASA homolog , tudor-domain containing 1 (TDRD1), tudor-domain containing 6 (TDRD6), and tudor-domain containing 7 (TDRD7) , transition protein 2 (Tnp2), RANBP9, as a known MVH interactor also localizes to it. Its formation is related to the coalescence of intermitochondrial cement granules. In fact, the formation of the chromatoid body is not required for microRNA biogenesis, but might be important for its action on target mRNAs (1). In mice, the chromatoid body is a structure resembles Gp, TDRD6 plays a role in establishing the body and the localization of piRNA pathway components to this body (2).

Reference
1. Woodruff, J. B., Hyman, A. A., & Boke, E. (2018) Organization and Function of Non-dynamic Biomolecular Condensates. Trends Biochem Sci, 43(2), 81-94. PMID: 30086300
2. Ma, L., Buchold, G. M., Greenbaum, M. P., Roy, A., Burns, K. H., Zhu, H., et al. (2009) GASZ is essential for male meiosis and suppression of retrotransposon expression in the male germline. PLoS Genet, 5(9), e1000635. PMID: 19730684


There are 101 genes.  Reviewed (0 or Unreviewed (101

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Mal-0207
ENSMLEG00000035536.1
A0A2K5Z4G6
2
LLPS-Mal-0477
ENSMLEG00000024522.1
A0A2K5XR05
3
LLPS-Mal-0719
ENSMLEG00000001003.1
A0A2K5XIB1
4
LLPS-Mal-0826
ENSMLEG00000033368.1
A0A2K5YSW6
5
LLPS-Mal-0898
ENSMLEG00000027792.1
A0A2K5XW65
6
LLPS-Mal-1556
ENSMLEG00000033690.1
A0A2K5YTY6
7
LLPS-Mal-1890
ENSMLEG00000027987.1
A0A2K5XWV5
8
LLPS-Mal-1907
ENSMLEG00000038413.1
A0A2K5ZKN2
9
LLPS-Mal-2124
ENSMLEG00000002856.1
A0A2K5XBV3
10
LLPS-Mal-2336
ENSMLEG00000040142.1
A0A2K5ZVQ1
11
LLPS-Mal-4229
ENSMLEG00000033479.1
A0A2K5YT00
12
LLPS-Mal-4269
ENSMLEG00000037534.1
A0A2K5ZFR1
13
LLPS-Mal-4452
ENSMLEG00000014825.1
A0A2K5XJG0
14
LLPS-Mal-3888
ENSMLEG00000011428.1
A0A2K5XHH2
ADAD1
15
LLPS-Mal-2250
ENSMLEG00000042324.1
A0A2K6A8N7
ADAD2
16
LLPS-Mal-0604
ENSMLEG00000041062.1
A0A2K6A140
AFAP1L2
17
LLPS-Mal-1649
ENSMLEG00000038874.1
A0A2K5ZPG6
AGO2
18
LLPS-Mal-2586
ENSMLEG00000042338.1
A0A2K6A8R2
AKAP4
19
LLPS-Mal-2267
ENSMLEG00000034914.1
A0A2K5Z0U3
ASZ1
20
LLPS-Mal-2625
ENSMLEG00000029049.1
A0A2K5Y2D6
CASC3
21
LLPS-Mal-0347
ENSMLEG00000035018.1
A0A2K5Z1F9
CD74
22
LLPS-Mal-0170
ENSMLEG00000034342.1
A0A2K5YXI2
CENPV
23
LLPS-Mal-0859
ENSMLEG00000041892.1
A0A2K6A618
CNBP
24
LLPS-Mal-3599
ENSMLEG00000000016.1
M9NAT7
COX1
25
LLPS-Mal-1331
ENSMLEG00000036808.1
A0A2K5ZBS2
CTSB
26
LLPS-Mal-1775
ENSMLEG00000042471.1
A0A2K6A9N7
DCP1A
27
LLPS-Mal-1400
ENSMLEG00000030787.1
A0A2K5YCX6
DDX1
28
LLPS-Mal-0121
ENSMLEG00000041703.1
A0A2K6A538
DDX25
29
LLPS-Mal-1089
ENSMLEG00000038233.1
A0A2K5ZK66
DDX4
30
LLPS-Mal-0429
ENSMLEG00000041700.1
A0A2K6A547
DDX5
31
LLPS-Mal-0061
ENSMLEG00000039925.1
A0A2K5ZUW5
DHX9
32
LLPS-Mal-1108
ENSMLEG00000034800.1
A0A2K5Z076
DICER1
33
LLPS-Mal-2115
ENSMLEG00000035003.1
A0A2K5Z1U8
EDC4
34
LLPS-Mal-0039
ENSMLEG00000032647.1
A0A2K5YNF9
EIF4A1
35
LLPS-Mal-2906
ENSMLEG00000032948.1
A0A2K5YPL8
EIF4A3
36
LLPS-Mal-0742
ENSMLEG00000021575.1
A0A2K5XND7
EIF4E
37
LLPS-Mal-0134
ENSMLEG00000030373.1
A0A2K5YA55
ENO4
38
LLPS-Mal-3101
ENSMLEG00000016144.1
A0A2K5XKN8
EWSR1
39
LLPS-Mal-3661
ENSMLEG00000038554.1
A0A2K5ZLG2
FABP9
40
LLPS-Mal-4695
ENSMLEG00000032598.1
A0A2K5YML3
FYCO1
41
LLPS-Mal-4132
ENSMLEG00000042692.1
A0A2K6AAQ4
GPX4
42
LLPS-Mal-3522
ENSMLEG00000009551.1
A0A2K5XGD6
HIST1H2BA
43
LLPS-Mal-1267
ENSMLEG00000040848.1
A0A2K5ZZW9
HNRNPA2B1
44
LLPS-Mal-1309
ENSMLEG00000023515.1
A0A2K5XPL0
HNRNPF
45
LLPS-Mal-4319
ENSMLEG00000042113.1
A0A2K6A853
HNRNPM
46
LLPS-Mal-2895
ENSMLEG00000040141.1
A0A2K5ZVM3
HNRNPU
47
LLPS-Mal-0012
ENSMLEG00000040549.1
A0A2K5ZYI1
HSP90AA1
48
LLPS-Mal-0108
ENSMLEG00000039096.1
A0A2K5ZPT0
HSPA2
49
LLPS-Mal-2735
ENSMLEG00000003021.1
A0A2K5XC38
IGF2BP3
50
LLPS-Mal-2795
ENSMLEG00000042847.1
A0A2K6AC37
ILF3
51
LLPS-Mal-2745
ENSMLEG00000034530.1
A0A2K5YYP0
IP6K1
52
LLPS-Mal-0923
ENSMLEG00000032825.1
A0A2K5YNW9
KHDRBS1
53
LLPS-Mal-3287
ENSMLEG00000010770.1
A0A2K5XH36
LAMP1
54
LLPS-Mal-0722
ENSMLEG00000029156.1
A0A2K5Y302
LYAR
55
LLPS-Mal-0211
ENSMLEG00000034260.1
A0A2K5YX08
MAEL
56
LLPS-Mal-1953
ENSMLEG00000040704.1
A0A2K5ZZ14
MAGOHB
57
LLPS-Mal-0671
ENSMLEG00000028935.1
A0A2K5Y1U5
NCL
58
LLPS-Mal-2305
ENSMLEG00000023576.1
A0A2K5XPP1
NEDD1
59
LLPS-Mal-4001
ENSMLEG00000033052.1
A0A2K5YQ73
ODF1
60
LLPS-Mal-1507
ENSMLEG00000027389.1
A0A2K5XUE3
PCBP1
61
LLPS-Mal-0570
ENSMLEG00000035718.1
A0A2K5Z5K0
PIWIL1
62
LLPS-Mal-0074
ENSMLEG00000041768.1
A0A2K6A5E1
PIWIL2
63
LLPS-Mal-1212
ENSMLEG00000005693.1
A0A2K5XDS6
PMPCB
64
LLPS-Mal-3181
ENSMLEG00000001440.1
A0A2K5XB33
PSIP1
65
LLPS-Mal-1666
ENSMLEG00000035962.1
A0A2K5Z6X2
RANGRF
66
LLPS-Mal-3048
ENSMLEG00000024601.1
A0A2K5XQR4
RBM14
67
LLPS-Mal-0364
ENSMLEG00000039155.1
A0A2K5ZQ39
RBM8A
68
LLPS-Mal-1641
ENSMLEG00000030227.1
A0A2K5Y9J4
RNF17
69
LLPS-Mal-0520
ENSMLEG00000032521.1
A0A2K5YMD0
RPL11
70
LLPS-Mal-0732
ENSMLEG00000041418.1
A0A2K6A3D4
RPL24
71
LLPS-Mal-0325
ENSMLEG00000029392.1
A0A2K5Y4B5
RPS14
72
LLPS-Mal-1085
ENSMLEG00000039296.1
A0A2K5ZR05
RPS8
73
LLPS-Mal-0518
ENSMLEG00000036142.1
A0A2K5Z9D3
SMG1
74
LLPS-Mal-1133
ENSMLEG00000029353.1
A0A2K5Y4H0
SMG6
75
LLPS-Mal-4109
ENSMLEG00000031233.1
A0A2K5YEY3
SPERT
76
LLPS-Mal-3635
ENSMLEG00000040509.1
A0A2K5ZXS2
SRSF1
77
LLPS-Mal-3291
ENSMLEG00000041179.1
A0A2K6A1R7
SRSF3
78
LLPS-Mal-3519
ENSMLEG00000038978.1
A0A2K5ZPA3
STK31
79
LLPS-Mal-3427
ENSMLEG00000032281.1
A0A2K5YL20
TDRD1
80
LLPS-Mal-0115
ENSMLEG00000039737.1
A0A2K5ZTH6
TDRD3
81
LLPS-Mal-0062
ENSMLEG00000043004.1
A0A2K6ACT4
TDRD5
82
LLPS-Mal-0362
ENSMLEG00000039418.1
A0A2K5ZRJ2
TDRD6
83
LLPS-Mal-1786
ENSMLEG00000037092.1
A0A2K5ZDE8
TDRD7
84
LLPS-Mal-1719
ENSMLEG00000032473.1
A0A2K5YM04
TDRD9
85
LLPS-Mal-3436
ENSMLEG00000019450.1
A0A2K5XLZ3
TEKT2
86
LLPS-Mal-0112
ENSMLEG00000029443.1
A0A2K5Y4N5
TEKT4
87
LLPS-Mal-0217
ENSMLEG00000044057.1
A0A2K6AJ21
TNP2
88
LLPS-Mal-0402
ENSMLEG00000030740.1
A0A2K5YCY1
TNPO1
89
LLPS-Mal-1996
ENSMLEG00000033571.1
A0A2K5YT58
TOMM34
90
LLPS-Mal-2062
ENSMLEG00000028904.1
A0A2K5Y1L8
TOP3B
91
LLPS-Mal-0481
ENSMLEG00000005550.1
A0A2K5XDL8
TRA2B
92
LLPS-Mal-2572
ENSMLEG00000030155.1
A0A2K5Y8Z7
TRPM5
93
LLPS-Mal-2770
ENSMLEG00000038192.1
A0A2K5ZJI4
TTC21B
94
LLPS-Mal-2498
ENSMLEG00000039442.1
A0A2K5ZRS2
UBTD1
95
LLPS-Mal-1499
ENSMLEG00000028404.1
A0A2K5XYX5
UPF1
96
LLPS-Mal-1302
ENSMLEG00000029360.1
A0A2K5YER8
USP9X
97
LLPS-Mal-1998
ENSMLEG00000037996.1
A0A2K5ZIJ1
VIM
98
LLPS-Mal-2340
ENSMLEG00000028974.1
A0A2K5Y2A9
VPS26A
99
LLPS-Mal-4635
ENSMLEG00000028564.1
A0A2K5XZH9
VPS35
100
LLPS-Mal-3940
ENSMLEG00000039452.1
A0A2K5ZRW6
YBX2
101
LLPS-Mal-3467
ENSMLEG00000043185.1
A0A2K6AE04
YTHDC2