Latimeria chalumnae      Chromatoid body


※ Chromatoid body introduction

    A single large granule of nuage, presents in post-meiotic spermatids is called the chromatoid body (1). Multiple proteins and some mRNAs have been found to localized to the chromatoid body including mouse VASA homolog , tudor-domain containing 1 (TDRD1), tudor-domain containing 6 (TDRD6), and tudor-domain containing 7 (TDRD7) , transition protein 2 (Tnp2), RANBP9, as a known MVH interactor also localizes to it. Its formation is related to the coalescence of intermitochondrial cement granules. In fact, the formation of the chromatoid body is not required for microRNA biogenesis, but might be important for its action on target mRNAs (1). In mice, the chromatoid body is a structure resembles Gp, TDRD6 plays a role in establishing the body and the localization of piRNA pathway components to this body (2).

Reference
1. Woodruff, J. B., Hyman, A. A., & Boke, E. (2018) Organization and Function of Non-dynamic Biomolecular Condensates. Trends Biochem Sci, 43(2), 81-94. PMID: 30086300
2. Ma, L., Buchold, G. M., Greenbaum, M. P., Roy, A., Burns, K. H., Zhu, H., et al. (2009) GASZ is essential for male meiosis and suppression of retrotransposon expression in the male germline. PLoS Genet, 5(9), e1000635. PMID: 19730684


There are 81 genes.  Reviewed (0 or Unreviewed (81

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Lac-1651
ENSLACG00000013431.1
H3B037
2
LLPS-Lac-2969
ENSLACG00000014646.1
H3B3Z8
3
LLPS-Lac-3209
ENSLACG00000007844.1
H3AGW1
4
LLPS-Lac-3074
ENSLACG00000004540.2
H3A635
ADAD1
5
LLPS-Lac-3679
ENSLACG00000013188.2
H3AZB3
AFAP1L2
6
LLPS-Lac-2465
ENSLACG00000001277.1
H2ZVK6
AGO2
7
LLPS-Lac-0370
ENSLACG00000016093.1
H3B8P9
ASZ1
8
LLPS-Lac-0850
ENSLACG00000013200.1
H3AZC7
CASC3
9
LLPS-Lac-3536
ENSLACG00000016022.1
H3B8G7
CD74
10
LLPS-Lac-2520
ENSLACG00000000122.1
H2ZRW8
CENPV
11
LLPS-Lac-0167
ENSLACG00000005327.1
H3A8M9
CNBP
12
LLPS-Lac-2885
ENSLACG00000008065.1
H3AHL6
CTSB
13
LLPS-Lac-0521
ENSLACG00000013895.1
H3B1K4
DCP1A
14
LLPS-Lac-0866
ENSLACG00000010529.1
H3AQP2
DDX1
15
LLPS-Lac-1069
ENSLACG00000015051.2
H3B5A9
DDX5
16
LLPS-Lac-3390
ENSLACG00000017767.1
H3BE94
DHX9
17
LLPS-Lac-2022
ENSLACG00000008302.1
H3AIE1
DICER1
18
LLPS-Lac-1401
ENSLACG00000016563.1
H3BA96
EDC4
19
LLPS-Lac-1347
ENSLACG00000000108.1
H2ZRV2
EIF4A3
20
LLPS-Lac-1425
ENSLACG00000008977.1
H3AKL4
EIF4E
21
LLPS-Lac-2836
ENSLACG00000017607.2
H3BDQ8
ELAVL1
22
LLPS-Lac-1061
ENSLACG00000008350.1
H3AIJ6
EWSR1
23
LLPS-Lac-2778
ENSLACG00000007800.1
H3AGQ7
FYCO1
24
LLPS-Lac-2299
ENSLACG00000013590.1
H3B0L4
HNRNPA2B1
25
LLPS-Lac-2716
ENSLACG00000008189.1
H3AI14
HNRNPA3
26
LLPS-Lac-1154
ENSLACG00000003613.1
H3A337
HNRNPDL
27
LLPS-Lac-0525
ENSLACG00000004394.2
H3A5M0
HNRNPH1
28
LLPS-Lac-1048
ENSLACG00000016814.1
H3BB40
HNRNPM
29
LLPS-Lac-2275
ENSLACG00000017463.1
H3BD92
HNRNPU
30
LLPS-Lac-3075
ENSLACG00000010351.1
H3AQ38
HSP90AB1
31
LLPS-Lac-3837
ENSLACG00000012967.1
H3AYL2
IGF2BP3
32
LLPS-Lac-0072
ENSLACG00000003810.2
H3A3R0
ILF3
33
LLPS-Lac-0098
ENSLACG00000007134.2
H3AEI9
IP6K1
34
LLPS-Lac-2947
ENSLACG00000005998.1
H3AAT9
LAMP1
35
LLPS-Lac-3638
ENSLACG00000002952.2
H3A0X9
LOC102346010
36
LLPS-Lac-0441
ENSLACG00000022167.1
M3XKV3
LOC102347971
37
LLPS-Lac-3784
ENSLACG00000017134.1
H3BC64
LOC102349397
38
LLPS-Lac-3170
ENSLACG00000002469.2
M3XLL1
LOC102351883
39
LLPS-Lac-0264
ENSLACG00000017750.1
H3BE74
LOC102355894
40
LLPS-Lac-1536
ENSLACG00000000733.1
H2ZTU7
LOC102357218
41
LLPS-Lac-3803
ENSLACG00000000806.1
H2ZU25
LOC102362904
42
LLPS-Lac-1433
ENSLACG00000005156.1
H3A836
LOC102363280
43
LLPS-Lac-0577
ENSLACG00000004350.1
H3A5H1
LOC102367360
44
LLPS-Lac-1428
ENSLACG00000007101.2
M3XHM0
LYAR
45
LLPS-Lac-1780
ENSLACG00000008630.2
M3XKM0
MAEL
46
LLPS-Lac-4021
ENSLACG00000022071.1
O03167
MT-CO1
47
LLPS-Lac-0490
ENSLACG00000004395.2
H3A5M3
PABPC1
48
LLPS-Lac-0668
ENSLACG00000018850.2
H3BHT1
PIWIL1
49
LLPS-Lac-0719
ENSLACG00000001069.1
H2ZUX2
PIWIL2
50
LLPS-Lac-1898
ENSLACG00000008245.1
H3AI74
PSIP1
51
LLPS-Lac-2067
ENSLACG00000003845.1
H3A3V0
RANBP9
52
LLPS-Lac-0828
ENSLACG00000006921.2
H3ADU3
RANGRF
53
LLPS-Lac-0649
ENSLACG00000014365.2
H3B334
RBM8A
54
LLPS-Lac-3254
ENSLACG00000000323.1
H2ZSI6
RNF17
55
LLPS-Lac-0808
ENSLACG00000010502.1
H3AQL2
RPL11
56
LLPS-Lac-3895
ENSLACG00000007868.1
H3AGY8
RPL23A
57
LLPS-Lac-0741
ENSLACG00000004303.1
H3A5B8
RPL24
58
LLPS-Lac-0077
ENSLACG00000016164.1
H3B8Y2
RPS14
59
LLPS-Lac-0411
ENSLACG00000006379.1
H3AC17
RPS8
60
LLPS-Lac-2460
ENSLACG00000014160.1
H3B2F5
SRSF1
61
LLPS-Lac-1992
ENSLACG00000008131.2
H3AHU1
SRSF3
62
LLPS-Lac-3543
ENSLACG00000015416.2
M3XKV0
STK31
63
LLPS-Lac-1631
ENSLACG00000011559.2
M3XI36
TDRD1
64
LLPS-Lac-1016
ENSLACG00000001412.1
H2ZW11
TDRD3
65
LLPS-Lac-1263
ENSLACG00000010837.1
H3ARN7
TDRD6
66
LLPS-Lac-2697
ENSLACG00000014886.1
H3B4S9
TDRD7
67
LLPS-Lac-1139
ENSLACG00000002257.1
H2ZYQ6
TDRD9
68
LLPS-Lac-1722
ENSLACG00000017301.2
H3BCQ7
TEKT2
69
LLPS-Lac-1653
ENSLACG00000008090.2
H3AHP5
TEKT4
70
LLPS-Lac-1331
ENSLACG00000012199.1
H3AW35
TNPO1
71
LLPS-Lac-0840
ENSLACG00000006277.1
H3ABQ4
TNRC6A
72
LLPS-Lac-3736
ENSLACG00000005351.1
H3A8Q6
TOMM34
73
LLPS-Lac-1551
ENSLACG00000013517.1
H3B0D1
TOP3B
74
LLPS-Lac-0091
ENSLACG00000013348.1
H3AZU0
TRA2B
75
LLPS-Lac-0713
ENSLACG00000004535.1
H3A629
TRPM5
76
LLPS-Lac-3702
ENSLACG00000003915.1
H3A431
TTC21B
77
LLPS-Lac-0937
ENSLACG00000008482.1
H3AIZ6
UPF1
78
LLPS-Lac-1396
ENSLACG00000014351.2
H3B318
VIM
79
LLPS-Lac-2393
ENSLACG00000007483.1
H3AFN1
VPS26A
80
LLPS-Lac-3939
ENSLACG00000009656.1
H3AMV4
VPS35
81
LLPS-Lac-1566
ENSLACG00000010991.1
H3AS52
YTHDC2