Felis catus      Chromatoid body


※ Chromatoid body introduction

    A single large granule of nuage, presents in post-meiotic spermatids is called the chromatoid body (1). Multiple proteins and some mRNAs have been found to localized to the chromatoid body including mouse VASA homolog , tudor-domain containing 1 (TDRD1), tudor-domain containing 6 (TDRD6), and tudor-domain containing 7 (TDRD7) , transition protein 2 (Tnp2), RANBP9, as a known MVH interactor also localizes to it. Its formation is related to the coalescence of intermitochondrial cement granules. In fact, the formation of the chromatoid body is not required for microRNA biogenesis, but might be important for its action on target mRNAs (1). In mice, the chromatoid body is a structure resembles Gp, TDRD6 plays a role in establishing the body and the localization of piRNA pathway components to this body (2).

Reference
1. Woodruff, J. B., Hyman, A. A., & Boke, E. (2018) Organization and Function of Non-dynamic Biomolecular Condensates. Trends Biochem Sci, 43(2), 81-94. PMID: 30086300
2. Ma, L., Buchold, G. M., Greenbaum, M. P., Roy, A., Burns, K. H., Zhu, H., et al. (2009) GASZ is essential for male meiosis and suppression of retrotransposon expression in the male germline. PLoS Genet, 5(9), e1000635. PMID: 19730684


There are 106 genes.  Reviewed (0 or Unreviewed (106

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Fec-3006
ENSFCAG00000007697.4
M3W868
2
LLPS-Fec-4687
ENSFCAG00000019180.4
M3X5Q6
ADAD1
3
LLPS-Fec-1298
ENSFCAG00000030183.3
M3XC73
ADAD2
4
LLPS-Fec-3749
ENSFCAG00000000634.5
M3VV47
AFAP1L2
5
LLPS-Fec-1215
ENSFCAG00000002782.5
A0A2I2UKJ7
AGO2
6
LLPS-Fec-3042
ENSFCAG00000031319.3
A0A337S251
AKAP4
7
LLPS-Fec-1154
ENSFCAG00000023842.3
M3WY25
ASZ1
8
LLPS-Fec-4388
ENSFCAG00000014998.5
M3WLR6
CASC3
9
LLPS-Fec-2527
ENSFCAG00000002036.4
M3VXS2
CD74
10
LLPS-Fec-2374
ENSFCAG00000031027.3
M3WQ29
CENPV
11
LLPS-Fec-0418
ENSFCAG00000042197.1
A0A337S5W7
CNBP
12
LLPS-Fec-0783
ENSFCAG00000015041.5
M3WLU0
CTSB
13
LLPS-Fec-1580
ENSFCAG00000003903.5
M3W163
DCP1A
14
LLPS-Fec-0228
ENSFCAG00000004680.5
M3W2M4
DDX1
15
LLPS-Fec-3029
ENSFCAG00000005341.5
A0A2I2U5E8
DDX25
16
LLPS-Fec-0102
ENSFCAG00000012560.5
M3WH61
DDX4
17
LLPS-Fec-1536
ENSFCAG00000003512.5
M3W0H3
DDX5
18
LLPS-Fec-0420
ENSFCAG00000019306.4
M3WPI7
DHX9
19
LLPS-Fec-2990
ENSFCAG00000003535.5
A0A2I2V473
DICER1
20
LLPS-Fec-3178
ENSFCAG00000012851.5
M3WHR0
EDC4
21
LLPS-Fec-1683
ENSFCAG00000030977.3
Q66RN5
EEF1A1
22
LLPS-Fec-0165
ENSFCAG00000024897.3
M3XBC3
EIF4A1
23
LLPS-Fec-2635
ENSFCAG00000008246.5
M3W982
EIF4A3
24
LLPS-Fec-0456
ENSFCAG00000009949.5
A0A337S7Q3
EIF4E
25
LLPS-Fec-0698
ENSFCAG00000034143.2
A0A2I2U6H1
ELAVL1
26
LLPS-Fec-3031
ENSFCAG00000001518.5
A0A2I2V5H4
ENO4
27
LLPS-Fec-1353
ENSFCAG00000004243.5
A0A337STI7
EWSR1
28
LLPS-Fec-1398
ENSFCAG00000038635.2
A0A2I2UFS8
FABP9
29
LLPS-Fec-4099
ENSFCAG00000027547.3
A0A2I2UZR5
FYCO1
30
LLPS-Fec-3883
ENSFCAG00000022744.3
M3X766
GPX4
31
LLPS-Fec-1405
ENSFCAG00000027765.3
M3XCQ1
HNRNPA2B1
32
LLPS-Fec-1745
ENSFCAG00000012146.5
M3WGE6
HNRNPA3
33
LLPS-Fec-1075
ENSFCAG00000000455.4
M3VUT2
HNRNPDL
34
LLPS-Fec-1977
ENSFCAG00000028219.3
M3XBR2
HNRNPF
35
LLPS-Fec-1923
ENSFCAG00000001204.5
M3VW73
HNRNPH1
36
LLPS-Fec-2867
ENSFCAG00000015218.5
M3WM68
HNRNPM
37
LLPS-Fec-0578
ENSFCAG00000002156.5
A0A337RZN8
HNRNPU
38
LLPS-Fec-1163
ENSFCAG00000000814.5
A0A337S6T1
HSP90AA1
39
LLPS-Fec-0799
ENSFCAG00000009764.5
M3WC29
HSP90AB1
40
LLPS-Fec-3089
ENSFCAG00000007820.4
M3W8G1
HSPA2
41
LLPS-Fec-2984
ENSFCAG00000030786.3
M3WQM6
IGF2BP3
42
LLPS-Fec-2934
ENSFCAG00000004887.5
M3W314
ILF3
43
LLPS-Fec-3842
ENSFCAG00000010677.5
A0A2I2U3X1
IP6K1
44
LLPS-Fec-4043
ENSFCAG00000006511.5
M3W616
KHDRBS1
45
LLPS-Fec-0528
ENSFCAG00000014247.5
C6GGN9
LAMP-1
46
LLPS-Fec-2018
ENSFCAG00000015735.5
A0A337S8L1
LDHA
47
LLPS-Fec-4788
ENSFCAG00000022091.3
M3W119
LOC101090556
48
LLPS-Fec-0807
ENSFCAG00000023368.3
M3WSM7
LOC101092762
49
LLPS-Fec-4151
ENSFCAG00000014668.3
M3WL43
LOC101096566
50
LLPS-Fec-2625
ENSFCAG00000028597.3
M3X7H4
LOC101100947
51
LLPS-Fec-0739
ENSFCAG00000040640.1
M3XAW8
LOC105260541
52
LLPS-Fec-2423
ENSFCAG00000043383.1
A0A337RXE8
LOC105260573
53
LLPS-Fec-0850
ENSFCAG00000028343.3
M3X302
LYAR
54
LLPS-Fec-1149
ENSFCAG00000009285.5
M3WB55
MAEL
55
LLPS-Fec-1805
ENSFCAG00000043981.1
A0A337RUQ3
MAGOHB
56
LLPS-Fec-0793
ENSFCAG00000032058.1
P48888
MT-CO1
57
LLPS-Fec-1672
ENSFCAG00000027622.3
M3WVY3
NCL
58
LLPS-Fec-3013
ENSFCAG00000031627.3
M3XFC8
NEDD1
59
LLPS-Fec-3423
ENSFCAG00000042534.1
M3W6P2
ODF1
60
LLPS-Fec-1517
ENSFCAG00000001874.5
M3VXF8
PABPC1
61
LLPS-Fec-0598
ENSFCAG00000022238.3
M3WS36
PCBP1
62
LLPS-Fec-0756
ENSFCAG00000023348.3
A0A337SP10
PCBP2
63
LLPS-Fec-0693
ENSFCAG00000014305.5
M3WKG8
PIWIL1
64
LLPS-Fec-3818
ENSFCAG00000012981.5
M3WHZ7
PIWIL2
65
LLPS-Fec-0591
ENSFCAG00000000636.5
M3VV49
PMPCB
66
LLPS-Fec-2265
ENSFCAG00000028662.3
Q66T72
PSIP1
67
LLPS-Fec-3941
ENSFCAG00000038622.2
A0A2I2UTC6
RANBP9
68
LLPS-Fec-1146
ENSFCAG00000027248.3
M3WQV0
RANGRF
69
LLPS-Fec-2606
ENSFCAG00000007392.4
M3W7N2
RBM14
70
LLPS-Fec-0036
ENSFCAG00000033936.2
A0A2I2V431
RBM8A
71
LLPS-Fec-4309
ENSFCAG00000027531.3
M3WX61
RNASE6
72
LLPS-Fec-3603
ENSFCAG00000004914.5
A0A337SRB9
RNF17
73
LLPS-Fec-0757
ENSFCAG00000042504.1
M3WUL6
RPL11
74
LLPS-Fec-1178
ENSFCAG00000004021.5
M3W1E8
RPL23A
75
LLPS-Fec-2183
ENSFCAG00000003327.5
Q66WF5
RPL24
76
LLPS-Fec-0454
ENSFCAG00000011085.4
M3WEF9
RPS14
77
LLPS-Fec-0792
ENSFCAG00000022602.3
M3XA78
RPS8
78
LLPS-Fec-0740
ENSFCAG00000010626.5
A0A337S4U3
SMG1
79
LLPS-Fec-3469
ENSFCAG00000028817.3
M3X9K3
SMG6
80
LLPS-Fec-3976
ENSFCAG00000040111.2
A0A2I2U145
SPERT
81
LLPS-Fec-1311
ENSFCAG00000002250.5
M3VY56
SRSF1
82
LLPS-Fec-0053
ENSFCAG00000001084.4
M3VVZ2
SRSF3
83
LLPS-Fec-0335
ENSFCAG00000028451.3
M3XES5
STK31
84
LLPS-Fec-0834
ENSFCAG00000000632.5
M3VV45
TDRD1
85
LLPS-Fec-2370
ENSFCAG00000022126.3
M3WV26
TDRD3
86
LLPS-Fec-3100
ENSFCAG00000001806.5
M3VXB3
TDRD5
87
LLPS-Fec-0545
ENSFCAG00000023001.3
M3XFG3
TDRD6
88
LLPS-Fec-1533
ENSFCAG00000002745.5
M3VZ22
TDRD7
89
LLPS-Fec-1053
ENSFCAG00000013807.5
M3WJI1
TDRD9
90
LLPS-Fec-0306
ENSFCAG00000012461.5
M3WH02
TEKT2
91
LLPS-Fec-0180
ENSFCAG00000023213.3
M3X0K6
TEKT4
92
LLPS-Fec-0829
ENSFCAG00000003606.4
B3LF33
Tnp2
93
LLPS-Fec-0730
ENSFCAG00000013181.5
A0A337S210
TNPO1
94
LLPS-Fec-4120
ENSFCAG00000025236.3
A0A2I2V1F7
TNRC6A
95
LLPS-Fec-0190
ENSFCAG00000010096.4
M3WCN9
TOMM34
96
LLPS-Fec-2806
ENSFCAG00000002631.5
M3VYV1
TOP3B
97
LLPS-Fec-2126
ENSFCAG00000010526.5
M3WDF5
TRA2B
98
LLPS-Fec-0434
ENSFCAG00000007863.5
M3W8I9
TTC21B
99
LLPS-Fec-3875
ENSFCAG00000024320.3
M3WWP4
UBTD1
100
LLPS-Fec-0016
ENSFCAG00000009757.5
M3WC21
UPF1
101
LLPS-Fec-1240
ENSFCAG00000011962.5
A0A2I2U2V7
USP9X
102
LLPS-Fec-1332
ENSFCAG00000046228.1
A0A2I2U8W9
VIM
103
LLPS-Fec-4315
ENSFCAG00000031306.3
M3XEG2
VPS26A
104
LLPS-Fec-2070
ENSFCAG00000001383.5
M3VWJ8
VPS35
105
LLPS-Fec-4560
ENSFCAG00000018097.4
M3WNQ9
YBX2
106
LLPS-Fec-0771
ENSFCAG00000031967.3
M3WVZ7
YTHDC2