Ciona savignyi      Chromatoid body


※ Chromatoid body introduction

    A single large granule of nuage, presents in post-meiotic spermatids is called the chromatoid body (1). Multiple proteins and some mRNAs have been found to localized to the chromatoid body including mouse VASA homolog , tudor-domain containing 1 (TDRD1), tudor-domain containing 6 (TDRD6), and tudor-domain containing 7 (TDRD7) , transition protein 2 (Tnp2), RANBP9, as a known MVH interactor also localizes to it. Its formation is related to the coalescence of intermitochondrial cement granules. In fact, the formation of the chromatoid body is not required for microRNA biogenesis, but might be important for its action on target mRNAs (1). In mice, the chromatoid body is a structure resembles Gp, TDRD6 plays a role in establishing the body and the localization of piRNA pathway components to this body (2).

Reference
1. Woodruff, J. B., Hyman, A. A., & Boke, E. (2018) Organization and Function of Non-dynamic Biomolecular Condensates. Trends Biochem Sci, 43(2), 81-94. PMID: 30086300
2. Ma, L., Buchold, G. M., Greenbaum, M. P., Roy, A., Burns, K. H., Zhu, H., et al. (2009) GASZ is essential for male meiosis and suppression of retrotransposon expression in the male germline. PLoS Genet, 5(9), e1000635. PMID: 19730684


There are 41 genes.  Reviewed (0 or Unreviewed (41

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Cis-0002
ENSCSAVG00000008949.1
H2ZCD1
2
LLPS-Cis-0031
ENSCSAVG00000002676.1
H2YGR1
3
LLPS-Cis-0071
ENSCSAVG00000000639.1
H2Y745
4
LLPS-Cis-0092
ENSCSAVG00000004124.1
H2YNK5
5
LLPS-Cis-0176
ENSCSAVG00000004751.1
H2YRK8
6
LLPS-Cis-0225
ENSCSAVG00000011349.1
H2ZP20
7
LLPS-Cis-0241
ENSCSAVG00000010885.1
H2ZLS4
8
LLPS-Cis-0294
ENSCSAVG00000007933.1
H2Z7H3
9
LLPS-Cis-0448
ENSCSAVG00000002215.1
H2YEJ0
10
LLPS-Cis-0485
ENSCSAVG00000002810.1
H2YHC1
11
LLPS-Cis-0503
ENSCSAVG00000006137.1
H2YYK2
12
LLPS-Cis-0509
ENSCSAVG00000009088.1
H2ZD20
13
LLPS-Cis-0525
ENSCSAVG00000004246.1
H2YP45
14
LLPS-Cis-0564
ENSCSAVG00000010270.1
H2ZIM0
15
LLPS-Cis-0566
ENSCSAVG00000011587.1
H2ZQ90
16
LLPS-Cis-0603
ENSCSAVG00000008975.1
H2ZCH5
17
LLPS-Cis-0614
ENSCSAVG00000006474.1
H2Z0F6
18
LLPS-Cis-0638
ENSCSAVG00000000159.1
H2Y4P1
19
LLPS-Cis-0771
ENSCSAVG00000001493.1
H2YB33
20
LLPS-Cis-0772
ENSCSAVG00000010981.1
H2ZM70
21
LLPS-Cis-0774
ENSCSAVG00000003651.1
H2YLA8
22
LLPS-Cis-0783
ENSCSAVG00000002146.1
H2YE70
23
LLPS-Cis-0868
ENSCSAVG00000003207.1
H2YJ67
24
LLPS-Cis-0871
ENSCSAVG00000003205.1
H2YJ63
25
LLPS-Cis-0885
ENSCSAVG00000001811.1
H2YCK7
26
LLPS-Cis-0980
ENSCSAVG00000007968.1
H2Z7N4
27
LLPS-Cis-1018
ENSCSAVG00000011078.1
H2ZMN5
28
LLPS-Cis-1254
ENSCSAVG00000009895.1
H2ZGV0
29
LLPS-Cis-1327
ENSCSAVG00000010820.1
H2ZLG3
30
LLPS-Cis-1331
ENSCSAVG00000003212.1
H2YJ77
31
LLPS-Cis-1352
ENSCSAVG00000002294.1
H2YEY8
32
LLPS-Cis-1371
ENSCSAVG00000006533.1
H2Z0R6
33
LLPS-Cis-1423
ENSCSAVG00000003028.1
H2YIC2
34
LLPS-Cis-1452
ENSCSAVG00000008942.1
H2ZCC1
35
LLPS-Cis-1466
ENSCSAVG00000007638.1
H2Z5Z4
36
LLPS-Cis-1616
ENSCSAVG00000000100.1
H2Y4C9
37
LLPS-Cis-1657
ENSCSAVG00000010777.1
H2ZL90
38
LLPS-Cis-1920
ENSCSAVG00000000392.1
H2Y5V1
39
LLPS-Cis-2014
ENSCSAVG00000003815.1
H2YM27
40
LLPS-Cis-2030
ENSCSAVG00000006093.1
H2YYD7
41
LLPS-Cis-1512
ENSCSAVG00000012483.1
Q85UI3
cox1