Astyanax mexicanus      Chromatoid body


※ Chromatoid body introduction

    A single large granule of nuage, presents in post-meiotic spermatids is called the chromatoid body (1). Multiple proteins and some mRNAs have been found to localized to the chromatoid body including mouse VASA homolog , tudor-domain containing 1 (TDRD1), tudor-domain containing 6 (TDRD6), and tudor-domain containing 7 (TDRD7) , transition protein 2 (Tnp2), RANBP9, as a known MVH interactor also localizes to it. Its formation is related to the coalescence of intermitochondrial cement granules. In fact, the formation of the chromatoid body is not required for microRNA biogenesis, but might be important for its action on target mRNAs (1). In mice, the chromatoid body is a structure resembles Gp, TDRD6 plays a role in establishing the body and the localization of piRNA pathway components to this body (2).

Reference
1. Woodruff, J. B., Hyman, A. A., & Boke, E. (2018) Organization and Function of Non-dynamic Biomolecular Condensates. Trends Biochem Sci, 43(2), 81-94. PMID: 30086300
2. Ma, L., Buchold, G. M., Greenbaum, M. P., Roy, A., Burns, K. H., Zhu, H., et al. (2009) GASZ is essential for male meiosis and suppression of retrotransposon expression in the male germline. PLoS Genet, 5(9), e1000635. PMID: 19730684


There are 80 genes.  Reviewed (0 or Unreviewed (80

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Asm-0011
ENSAMXG00000019225.2
W5LIY9
2
LLPS-Asm-0042
ENSAMXG00000009842.2
W5KR97
3
LLPS-Asm-0075
ENSAMXG00000005433.2
W5KDA1
4
LLPS-Asm-0108
ENSAMXG00000007214.2
W5KIJ4
5
LLPS-Asm-0133
ENSAMXG00000006847.2
W5KHI1
6
LLPS-Asm-0154
ENSAMXG00000030251.1
A0A3B1JGP7
7
LLPS-Asm-0169
ENSAMXG00000017326.2
W5LDM5
8
LLPS-Asm-0214
ENSAMXG00000034169.1
A0A3B1JG10
9
LLPS-Asm-0220
ENSAMXG00000015842.2
W5L8Z7
10
LLPS-Asm-0266
ENSAMXG00000010730.2
W5KTV6
11
LLPS-Asm-0314
ENSAMXG00000000055.2
A0A3B1JCF0
12
LLPS-Asm-0334
ENSAMXG00000009459.2
W5KQ65
13
LLPS-Asm-0345
ENSAMXG00000006243.2
A0A3B1J9M0
14
LLPS-Asm-0373
ENSAMXG00000025038.2
W5LS51
15
LLPS-Asm-0386
ENSAMXG00000034710.1
A0A3B1K7S7
16
LLPS-Asm-0422
ENSAMXG00000009633.2
W5KQP6
17
LLPS-Asm-0431
ENSAMXG00000008840.2
A0A3B1JCB0
18
LLPS-Asm-0446
ENSAMXG00000018517.2
W5LGY1
19
LLPS-Asm-0470
ENSAMXG00000020882.2
A0A3B1JFX3
20
LLPS-Asm-0492
ENSAMXG00000041744.1
A0A3B1K9F8
21
LLPS-Asm-0541
ENSAMXG00000042187.1
A0A3B1KC06
22
LLPS-Asm-0564
ENSAMXG00000007453.2
A0A3B1JKX9
23
LLPS-Asm-0570
ENSAMXG00000016858.2
A0A3B1IFT2
24
LLPS-Asm-0577
ENSAMXG00000041598.1
A0A3B1IKI3
25
LLPS-Asm-0750
ENSAMXG00000008599.2
W5KMP6
26
LLPS-Asm-0767
ENSAMXG00000019919.2
W5LLR6
27
LLPS-Asm-0799
ENSAMXG00000007541.2
W5KJJ5
28
LLPS-Asm-0832
ENSAMXG00000020531.2
A0A3B1ITR2
29
LLPS-Asm-0857
ENSAMXG00000000509.2
A0A3B1IQV6
30
LLPS-Asm-0927
ENSAMXG00000001495.2
W5K1Q4
31
LLPS-Asm-1026
ENSAMXG00000015412.2
A0A3B1JCX1
32
LLPS-Asm-1141
ENSAMXG00000002483.2
W5KE37
33
LLPS-Asm-1200
ENSAMXG00000002827.2
W5K5N8
34
LLPS-Asm-1201
ENSAMXG00000001746.2
A0A3B1JCX7
35
LLPS-Asm-1335
ENSAMXG00000036727.1
A0A3B1IRF5
36
LLPS-Asm-1351
ENSAMXG00000015370.2
W5L7R9
37
LLPS-Asm-1364
ENSAMXG00000020572.2
W5LMY2
38
LLPS-Asm-1425
ENSAMXG00000016073.2
W5L9Q8
39
LLPS-Asm-1455
ENSAMXG00000019608.2
W5LK27
40
LLPS-Asm-1595
ENSAMXG00000010917.2
W5KUF8
41
LLPS-Asm-1606
ENSAMXG00000011699.2
W5KWR5
42
LLPS-Asm-1683
ENSAMXG00000035996.1
A0A3B1J8X2
43
LLPS-Asm-1693
ENSAMXG00000040754.1
A0A3B1J550
44
LLPS-Asm-1694
ENSAMXG00000002100.2
W5K3I1
45
LLPS-Asm-1821
ENSAMXG00000014974.2
A0A3B1JNR3
46
LLPS-Asm-1888
ENSAMXG00000035414.1
A0A3B1J5S2
47
LLPS-Asm-1924
ENSAMXG00000031608.1
A0A3B1J8J1
48
LLPS-Asm-2024
ENSAMXG00000031223.1
A0A3B1J8Q2
49
LLPS-Asm-2122
ENSAMXG00000043066.1
A0A3B1JND3
50
LLPS-Asm-2178
ENSAMXG00000020901.2
W5LNV2
51
LLPS-Asm-2190
ENSAMXG00000041156.1
A0A3B1INA5
52
LLPS-Asm-2298
ENSAMXG00000024526.2
A0A3B1J673
53
LLPS-Asm-2311
ENSAMXG00000040608.1
A0A3B1J2U2
54
LLPS-Asm-2361
ENSAMXG00000011002.2
W5KUQ3
55
LLPS-Asm-2483
ENSAMXG00000015146.2
W5L7K5
56
LLPS-Asm-2609
ENSAMXG00000032452.1
A0A3B1KJ32
57
LLPS-Asm-2616
ENSAMXG00000000447.2
W5JYP6
58
LLPS-Asm-2866
ENSAMXG00000001622.2
W5K243
59
LLPS-Asm-2884
ENSAMXG00000021360.2
W5LPY4
60
LLPS-Asm-2923
ENSAMXG00000041798.1
A0A3B1JHW5
61
LLPS-Asm-2924
ENSAMXG00000010288.2
W5KSP0
62
LLPS-Asm-3043
ENSAMXG00000001647.2
W5K288
63
LLPS-Asm-3049
ENSAMXG00000032467.1
A0A3B1IS86
64
LLPS-Asm-3082
ENSAMXG00000003096.2
W5K6E0
65
LLPS-Asm-3341
ENSAMXG00000005645.2
W5KDX9
66
LLPS-Asm-3346
ENSAMXG00000010029.2
W5KRT6
67
LLPS-Asm-3407
ENSAMXG00000002577.2
W5K4X5
68
LLPS-Asm-3424
ENSAMXG00000008974.2
W5KPM7
69
LLPS-Asm-3539
ENSAMXG00000001225.2
W5K0Z9
70
LLPS-Asm-3544
ENSAMXG00000017846.2
W5LEX2
71
LLPS-Asm-3692
ENSAMXG00000011630.2
W5KWJ0
72
LLPS-Asm-3746
ENSAMXG00000014208.2
W5L472
73
LLPS-Asm-3782
ENSAMXG00000010419.2
W5KSZ3
74
LLPS-Asm-3825
ENSAMXG00000016301.2
W5LAE0
75
LLPS-Asm-3901
ENSAMXG00000041988.1
A0A3B1JP83
76
LLPS-Asm-0287
ENSAMXG00000014587.2
A0A3B1KLJ8
AGO2
77
LLPS-Asm-2919
ENSAMXG00000015550.2
A0A3B1JFV6
DDX5
78
LLPS-Asm-1471
ENSAMXG00000004487.2
W5KAI5
EEF1A1
79
LLPS-Asm-1445
ENSAMXG00000039469.1
A0A3B1IEU4
TRA2B (1 of many)
80
LLPS-Asm-2694
ENSAMXG00000008735.2
W5KNU3
YTHDC2