Anolis carolinensis      Chromatoid body


※ Chromatoid body introduction

    A single large granule of nuage, presents in post-meiotic spermatids is called the chromatoid body (1). Multiple proteins and some mRNAs have been found to localized to the chromatoid body including mouse VASA homolog , tudor-domain containing 1 (TDRD1), tudor-domain containing 6 (TDRD6), and tudor-domain containing 7 (TDRD7) , transition protein 2 (Tnp2), RANBP9, as a known MVH interactor also localizes to it. Its formation is related to the coalescence of intermitochondrial cement granules. In fact, the formation of the chromatoid body is not required for microRNA biogenesis, but might be important for its action on target mRNAs (1). In mice, the chromatoid body is a structure resembles Gp, TDRD6 plays a role in establishing the body and the localization of piRNA pathway components to this body (2).

Reference
1. Woodruff, J. B., Hyman, A. A., & Boke, E. (2018) Organization and Function of Non-dynamic Biomolecular Condensates. Trends Biochem Sci, 43(2), 81-94. PMID: 30086300
2. Ma, L., Buchold, G. M., Greenbaum, M. P., Roy, A., Burns, K. H., Zhu, H., et al. (2009) GASZ is essential for male meiosis and suppression of retrotransposon expression in the male germline. PLoS Genet, 5(9), e1000635. PMID: 19730684


There are 85 genes.  Reviewed (0 or Unreviewed (85

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Anc-2368
ENSACAG00000010935.2
H9GGZ4
2
LLPS-Anc-2428
ENSACAG00000012236.2
H9GIN8
3
LLPS-Anc-2904
ENSACAG00000007756.3
G1KXS1
4
LLPS-Anc-2913
ENSACAG00000011970.3
G1KLP7
ADAD1
5
LLPS-Anc-3664
ENSACAG00000000939.3
H9G4E7
adad2
6
LLPS-Anc-1303
ENSACAG00000009734.3
H9GFN2
AFAP1L2
7
LLPS-Anc-2268
ENSACAG00000000167.3
G1K8D5
AGO2
8
LLPS-Anc-3476
ENSACAG00000008056.3
G1KHF2
ASZ1
9
LLPS-Anc-0731
ENSACAG00000002674.3
G1KB37
CASC3
10
LLPS-Anc-2413
ENSACAG00000015007.3
G1KQJ0
CD74
11
LLPS-Anc-2465
ENSACAG00000028225.1
B3GSZ2
COX1
12
LLPS-Anc-0044
ENSACAG00000015051.3
H9GLW9
CTSB
13
LLPS-Anc-2620
ENSACAG00000011028.3
G1KKS9
DCP1A
14
LLPS-Anc-1040
ENSACAG00000011036.3
G1KL19
DDX1
15
LLPS-Anc-3070
ENSACAG00000000173.3
H9G3C5
DDX25
16
LLPS-Anc-1522
ENSACAG00000000843.3
H9G4M7
ddx5
17
LLPS-Anc-1432
ENSACAG00000005023.3
H9G9V0
DHX9
18
LLPS-Anc-0050
ENSACAG00000013033.3
G1KND9
DICER1
19
LLPS-Anc-0052
ENSACAG00000001561.3
H9G5F0
EDC4
20
LLPS-Anc-1473
ENSACAG00000004556.3
H9G990
eef1a1
21
LLPS-Anc-0796
ENSACAG00000014384.3
G1KPX6
EIF4A3
22
LLPS-Anc-0356
ENSACAG00000014186.3
H9GKT5
EIF4E
23
LLPS-Anc-2658
ENSACAG00000010140.3
H9GG19
ENO4
24
LLPS-Anc-2346
ENSACAG00000009298.2
H9GF55
EWSR1
25
LLPS-Anc-2570
ENSACAG00000014119.2
H9GT12
FYCO1
26
LLPS-Anc-2806
ENSACAG00000007209.2
H9GCF6
gpx4
27
LLPS-Anc-1041
ENSACAG00000012992.3
G1KN60
HNRNPA2B1
28
LLPS-Anc-1696
ENSACAG00000010416.3
G1KK24
HNRNPDL
29
LLPS-Anc-1653
ENSACAG00000016323.3
G1KSH5
hnrnph1
30
LLPS-Anc-0392
ENSACAG00000004511.2
H9G948
HNRNPU
31
LLPS-Anc-0646
ENSACAG00000000151.3
H9G3B6
hsp90aa1
32
LLPS-Anc-1968
ENSACAG00000014791.3
G1KQE0
HSP90AB1
33
LLPS-Anc-0104
ENSACAG00000015774.1
G1KRK2
HSPA2
34
LLPS-Anc-2972
ENSACAG00000007267.3
G1KGD5
IP6K1
35
LLPS-Anc-0012
ENSACAG00000011693.3
H9GI32
KHDRBS1
36
LLPS-Anc-2266
ENSACAG00000000264.3
G1K8E2
LAMP1
37
LLPS-Anc-0643
ENSACAG00000000061.3
G1K888
ldha
38
LLPS-Anc-0220
ENSACAG00000015614.3
H9GML7
LOC100554323
39
LLPS-Anc-0833
ENSACAG00000004414.1
H9GM55
LOC100558489
40
LLPS-Anc-0768
ENSACAG00000013076.3
G1KN67
LOC100560655
41
LLPS-Anc-3118
ENSACAG00000002559.3
G1KAW4
LOC100567848
42
LLPS-Anc-2536
ENSACAG00000015875.2
G1KRS8
LOC103278164
43
LLPS-Anc-0910
ENSACAG00000029327.1
R4GC38
mael
44
LLPS-Anc-1925
ENSACAG00000001006.3
H9G4M1
ncl
45
LLPS-Anc-3206
ENSACAG00000013337.3
G1KNP6
nedd1
46
LLPS-Anc-1854
ENSACAG00000009176.3
G1KII8
ODF1
47
LLPS-Anc-0362
ENSACAG00000016470.3
H9GNC3
PABPC1
48
LLPS-Anc-1301
ENSACAG00000010657.3
H9GGR2
PIWIL2
49
LLPS-Anc-1329
ENSACAG00000006504.3
G1KFG6
PMPCB
50
LLPS-Anc-3328
ENSACAG00000017757.3
G1KUD0
psip1
51
LLPS-Anc-0594
ENSACAG00000003604.3
G1KC27
RANBP9
52
LLPS-Anc-2853
ENSACAG00000003563.3
H9GSU3
RANGRF
53
LLPS-Anc-1282
ENSACAG00000012696.3
H9GJ57
RBM14
54
LLPS-Anc-2696
ENSACAG00000001418.3
G1K9Q0
RNF17
55
LLPS-Anc-0839
ENSACAG00000005058.2
H9G9U6
RPL11
56
LLPS-Anc-0170
ENSACAG00000005311.3
H9GA26
RPL23A
57
LLPS-Anc-2819
ENSACAG00000012029.2
G1KLR6
RPL24
58
LLPS-Anc-0746
ENSACAG00000015004.3
G1KQI8
RPS14
59
LLPS-Anc-0759
ENSACAG00000015697.3
G1KRF8
RPS8
60
LLPS-Anc-2302
ENSACAG00000000960.3
H9G4S7
SMG1
61
LLPS-Anc-0341
ENSACAG00000011783.3
H9GI56
SMG6
62
LLPS-Anc-2220
ENSACAG00000005542.2
H9GAB8
srsf1
63
LLPS-Anc-2885
ENSACAG00000016637.2
G1KSV6
SRSF3
64
LLPS-Anc-3732
ENSACAG00000013399.3
G1KNT3
STK31
65
LLPS-Anc-3123
ENSACAG00000009854.3
H9GFS7
TDRD1
66
LLPS-Anc-3478
ENSACAG00000004923.3
G1KDC8
TDRD3
67
LLPS-Anc-1340
ENSACAG00000001245.3
G1KVT0
TDRD5
68
LLPS-Anc-2065
ENSACAG00000013170.2
G1KNB7
TDRD6
69
LLPS-Anc-2175
ENSACAG00000001003.3
H9G4G6
TDRD7
70
LLPS-Anc-2544
ENSACAG00000010862.3
G1KKN5
TDRD9
71
LLPS-Anc-1882
ENSACAG00000003567.2
H9G7S2
TEKT2
72
LLPS-Anc-1616
ENSACAG00000006071.1
H9GAX1
TEKT4
73
LLPS-Anc-0577
ENSACAG00000009599.3
G1KJ76
TNPO1
74
LLPS-Anc-3399
ENSACAG00000011857.3
H9GIC8
TNRC6A
75
LLPS-Anc-0290
ENSACAG00000012037.3
G1KLT9
TOMM34
76
LLPS-Anc-2296
ENSACAG00000001551.2
H9G5D6
TOP3B
77
LLPS-Anc-1000
ENSACAG00000029688.1
R4GAT3
TRA2B
78
LLPS-Anc-1015
ENSACAG00000002696.2
H9G6Q4
TTC21B
79
LLPS-Anc-3424
ENSACAG00000002776.3
G1KB52
UBTD1
80
LLPS-Anc-0533
ENSACAG00000017937.3
G1KUK4
usp9x
81
LLPS-Anc-0491
ENSACAG00000005142.3
G1KDR6
VIM
82
LLPS-Anc-2503
ENSACAG00000009758.2
H9GFK5
VPS26A
83
LLPS-Anc-2136
ENSACAG00000013293.3
H9GJW8
VPS35
84
LLPS-Anc-0877
ENSACAG00000001017.3
H9G4I4
YBX2
85
LLPS-Anc-2533
ENSACAG00000007754.2
H9GD25
YTHDC2