Ailuropoda melanoleuca      Chromatoid body


※ Chromatoid body introduction

    A single large granule of nuage, presents in post-meiotic spermatids is called the chromatoid body (1). Multiple proteins and some mRNAs have been found to localized to the chromatoid body including mouse VASA homolog , tudor-domain containing 1 (TDRD1), tudor-domain containing 6 (TDRD6), and tudor-domain containing 7 (TDRD7) , transition protein 2 (Tnp2), RANBP9, as a known MVH interactor also localizes to it. Its formation is related to the coalescence of intermitochondrial cement granules. In fact, the formation of the chromatoid body is not required for microRNA biogenesis, but might be important for its action on target mRNAs (1). In mice, the chromatoid body is a structure resembles Gp, TDRD6 plays a role in establishing the body and the localization of piRNA pathway components to this body (2).

Reference
1. Woodruff, J. B., Hyman, A. A., & Boke, E. (2018) Organization and Function of Non-dynamic Biomolecular Condensates. Trends Biochem Sci, 43(2), 81-94. PMID: 30086300
2. Ma, L., Buchold, G. M., Greenbaum, M. P., Roy, A., Burns, K. H., Zhu, H., et al. (2009) GASZ is essential for male meiosis and suppression of retrotransposon expression in the male germline. PLoS Genet, 5(9), e1000635. PMID: 19730684


There are 96 genes.  Reviewed (0 or Unreviewed (96

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Aim-0084
ENSAMEG00000017854.1
G1MHP1
2
LLPS-Aim-0221
ENSAMEG00000018482.1
G1MJN1
3
LLPS-Aim-1567
ENSAMEG00000018827.1
G1MKK0
4
LLPS-Aim-3183
ENSAMEG00000004716.1
G1LDJ2
5
LLPS-Aim-3827
ENSAMEG00000008298.1
G1LP39
6
LLPS-Aim-1736
ENSAMEG00000005920.1
G1LH59
ADAD1
7
LLPS-Aim-0154
ENSAMEG00000006263.1
G1LI48
ADAD2
8
LLPS-Aim-0932
ENSAMEG00000015160.1
G1M9F4
AFAP1L2
9
LLPS-Aim-1246
ENSAMEG00000005019.1
G1LEP7
AGO2
10
LLPS-Aim-1608
ENSAMEG00000012069.1
G1M044
AKAP4
11
LLPS-Aim-2543
ENSAMEG00000001244.1
G1L349
ASZ1
12
LLPS-Aim-3655
ENSAMEG00000007764.1
G1LMI1
CASC3
13
LLPS-Aim-2160
ENSAMEG00000004654.1
G1LDD9
CD74
14
LLPS-Aim-1866
ENSAMEG00000015334.1
G1M9Z3
CNBP
15
LLPS-Aim-2252
ENSAMEG00000023436.1
A5JFJ8
COI
16
LLPS-Aim-2385
ENSAMEG00000006251.1
G1LI42
CTSB
17
LLPS-Aim-0005
ENSAMEG00000006039.1
D2GVD1
CYCS
18
LLPS-Aim-1286
ENSAMEG00000007875.1
D2HAR7
DCP1A
19
LLPS-Aim-0176
ENSAMEG00000001071.1
G1L2R9
DDX1
20
LLPS-Aim-1159
ENSAMEG00000000138.1
G1KZV1
DDX25
21
LLPS-Aim-1633
ENSAMEG00000013960.1
G1M5Z6
DDX4
22
LLPS-Aim-0485
ENSAMEG00000002685.1
G1L7I9
DDX5
23
LLPS-Aim-3836
ENSAMEG00000002233.1
G1L659
DHX9
24
LLPS-Aim-2895
ENSAMEG00000017551.1
G1MGS5
EDC4
25
LLPS-Aim-0646
ENSAMEG00000007786.1
G1LMH6
EEF1A1
26
LLPS-Aim-0017
ENSAMEG00000016753.1
G1MEC4
EIF4A1
27
LLPS-Aim-3351
ENSAMEG00000015194.1
G1M9J0
EIF4A3
28
LLPS-Aim-0234
ENSAMEG00000013873.1
G1M5K7
EIF4E
29
LLPS-Aim-2602
ENSAMEG00000008657.1
G1LPZ7
ELAVL1
30
LLPS-Aim-2674
ENSAMEG00000014046.1
G1M643
ENO4
31
LLPS-Aim-3835
ENSAMEG00000014584.1
G1M7P7
FABP9
32
LLPS-Aim-1321
ENSAMEG00000005983.1
G1LHD9
HNRNPA2B1
33
LLPS-Aim-1770
ENSAMEG00000007660.1
G1LM79
HNRNPDL
34
LLPS-Aim-1006
ENSAMEG00000018983.1
D2H6F1
HNRNPF
35
LLPS-Aim-1763
ENSAMEG00000008888.1
D2HGC3
HNRNPH1
36
LLPS-Aim-3412
ENSAMEG00000004979.1
G1LEE5
HNRNPM
37
LLPS-Aim-2054
ENSAMEG00000009145.1
G1LRJ2
HNRNPU
38
LLPS-Aim-1301
ENSAMEG00000006078.1
D2HVQ7
HSP90AA1
39
LLPS-Aim-2395
ENSAMEG00000011809.1
G1LZE2
HSP90AB1
40
LLPS-Aim-1279
ENSAMEG00000019521.1
D2GYI3
HSPA2
41
LLPS-Aim-0738
ENSAMEG00000003485.1
G1L9V3
IGF2BP3
42
LLPS-Aim-2018
ENSAMEG00000011152.1
G1LXI8
ILF3
43
LLPS-Aim-1226
ENSAMEG00000012301.1
G1M0U3
IP6K1
44
LLPS-Aim-1656
ENSAMEG00000007969.1
D2HI64
KHDRBS1
45
LLPS-Aim-1539
ENSAMEG00000004770.1
G1LDV3
LAMP1
46
LLPS-Aim-2912
ENSAMEG00000019835.1
G1MNE3
LOC100466538
47
LLPS-Aim-1800
ENSAMEG00000020270.1
D2H2K2
LOC100468404
48
LLPS-Aim-0544
ENSAMEG00000011042.1
G1LX08
LOC100470688
49
LLPS-Aim-0597
ENSAMEG00000018479.1
D2HWJ2
LOC100482789
50
LLPS-Aim-1593
ENSAMEG00000013658.1
D2HLR9
LYAR
51
LLPS-Aim-1254
ENSAMEG00000000018.1
G1KZH0
MAEL
52
LLPS-Aim-3776
ENSAMEG00000009447.1
G1LS99
MAGOHB
53
LLPS-Aim-0190
ENSAMEG00000016289.1
G1MD31
NCL
54
LLPS-Aim-1408
ENSAMEG00000004999.1
G1LEG8
NEDD1
55
LLPS-Aim-2574
ENSAMEG00000014784.1
D2HJX0
ODF1
56
LLPS-Aim-2318
ENSAMEG00000000348.1
G1L0J4
PABPC1
57
LLPS-Aim-1991
ENSAMEG00000016094.1
G1MCC0
PCBP1
58
LLPS-Aim-0870
ENSAMEG00000012520.1
G1M1L1
PCBP2
59
LLPS-Aim-1391
ENSAMEG00000006533.1
D2HWM8
PIWIL1
60
LLPS-Aim-0882
ENSAMEG00000003171.1
D2H044
PIWIL2
61
LLPS-Aim-1980
ENSAMEG00000015309.1
G1MA07
PMPCB
62
LLPS-Aim-0445
ENSAMEG00000000415.1
G1L0T3
RANBP9
63
LLPS-Aim-3200
ENSAMEG00000002499.1
G1L6V3
RANGRF
64
LLPS-Aim-0603
ENSAMEG00000017623.1
G1MGY3
RBM8A
65
LLPS-Aim-1233
ENSAMEG00000017340.1
G1MG56
RNF17
66
LLPS-Aim-0934
ENSAMEG00000009704.1
D2GWC5
RPL11
67
LLPS-Aim-0682
ENSAMEG00000004684.1
F2X266
Rpl23A
68
LLPS-Aim-1302
ENSAMEG00000003740.1
G1LAN3
RPL24
69
LLPS-Aim-0621
ENSAMEG00000004644.1
G1LDB6
RPS14
70
LLPS-Aim-1644
ENSAMEG00000014147.1
D2HUN9
RPS8
71
LLPS-Aim-1750
ENSAMEG00000007632.1
G1LM72
SMG6
72
LLPS-Aim-2064
ENSAMEG00000013110.1
D2H0K1
SPERT
73
LLPS-Aim-0087
ENSAMEG00000002635.1
G1L799
SRSF1
74
LLPS-Aim-1519
ENSAMEG00000000268.1
G1L082
SRSF3
75
LLPS-Aim-2137
ENSAMEG00000009006.1
G1LR26
STK31
76
LLPS-Aim-0778
ENSAMEG00000015182.1
G1M9K2
TDRD1
77
LLPS-Aim-3026
ENSAMEG00000000082.1
G1KZN5
TDRD3
78
LLPS-Aim-3282
ENSAMEG00000014736.1
G1M861
TDRD5
79
LLPS-Aim-0625
ENSAMEG00000001687.1
G1L4F4
TDRD6
80
LLPS-Aim-0245
ENSAMEG00000004876.1
G1LE45
TDRD7
81
LLPS-Aim-0970
ENSAMEG00000018095.1
G1MIF2
TDRD9
82
LLPS-Aim-0274
ENSAMEG00000000473.1
G1L0W0
TEKT2
83
LLPS-Aim-2269
ENSAMEG00000007524.1
G1LLW6
TEKT4
84
LLPS-Aim-1029
ENSAMEG00000007147.1
G1LKS9
TNPO1
85
LLPS-Aim-4355
ENSAMEG00000009333.1
G1LRX8
TNRC6A
86
LLPS-Aim-1362
ENSAMEG00000007454.1
G1LLS2
TOP3B
87
LLPS-Aim-0326
ENSAMEG00000016751.1
G1MEC0
TRA2B
88
LLPS-Aim-0888
ENSAMEG00000002252.1
G1L680
TRPM5
89
LLPS-Aim-0441
ENSAMEG00000015663.1
G1MB04
TTC21B
90
LLPS-Aim-2923
ENSAMEG00000000112.1
G1KZR4
UBTD1
91
LLPS-Aim-0319
ENSAMEG00000011474.1
G1LYD2
UPF1
92
LLPS-Aim-0177
ENSAMEG00000006858.1
G1LK65
USP9X
93
LLPS-Aim-1914
ENSAMEG00000010536.1
G1LVM5
VIM
94
LLPS-Aim-2561
ENSAMEG00000017963.1
D2GXI1
VPS26A
95
LLPS-Aim-1935
ENSAMEG00000018344.1
D2GWQ1
VPS35
96
LLPS-Aim-2268
ENSAMEG00000006598.1
G1LJ67
YTHDC2