• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Zyt-0070
PDB1

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Pyruvate dehydrogenase E1 component subunit beta
Gene Name: PDB1, MYCGRDRAFT_69357
Ensembl Gene: Mycgr3G69357
Ensembl Protein: Mycgr3P69357
Organism: Zymoseptoria tritici
Taxa ID: 336722
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Nucleolus, OthersPredicted from orthologs(View)

▼ FUNCTION

The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

▼ CROSS REFERENCE

DatabaseNucleotide IDProtein ID
EnsemblMycgr3T69357Mycgr3P69357
UniProtF9X6P5, F9X6P5_ZYMTI
GeneBankCM001198EGP89570.1
RefSeqXM_003854546.1XP_003854594.1

▼ SEQUENCE

Protein Sequence (FASTA)
1     MVAARFVRPA  AQLLRTQPSA  ALSRSTFQKL  SVPAVSRWRN  YATGQKEMTV  REALNEAMVE  60
61    EMEKNPKVFV  LGEEVAQYNG  AYKVTKGLLD  RFGDKRVIDS  PITESGFCGL  TVGAALAGLH  120
121   PVCEFMTFNF  AMQAIDQIIN  SAAKTHYMSG  GIQPCNITFR  GPNGFAAGVA  AQHSQDYSAW  180
181   YGSIPGLKVV  APYSAEDAKG  LLKAAIRDPN  PVCVLENELL  YGLSFPMSEE  AQSDDFVIPF  240
241   GKAKIERPGK  DLTIVTLSRC  VGQSLQAAEI  LKSKYGVEAE  VINLRSIKPL  DVEAIVKSVK  300
301   KTGHMMAVES  GFPSFGVGAE  IIALTAEYAF  DYLEAPPVRV  TGAEVPTPYA  QKLEEMAFPT  360
361   EQLIADYAAK  LLRV  374
Nucleotide CDS Sequence (FASTA)
1     ATGGTCGCCG  CCCGCTTCGT  GCGCCCCGCG  GCGCAGCTCC  TCCGCACCCA  ACCCTCCGCA  60
61    GCTCTCTCCC  GATCCACCTT  TCAAAAATTG  TCAGTGCCGG  CCGTGTCACG  ATGGAGGAAC  120
121   TATGCGACGG  GTCAGAAGGA  GATGACGGTC  CGTGAGGCGC  TCAATGAGGC  CATGGTCGAG  180
181   GAGATGGAGA  AGAACCCAAA  AGTTTTCGTC  CTTGGTGAGG  AGGTTGCACA  GTACAACGGC  240
241   GCATACAAGG  TCACCAAAGG  CCTACTAGAT  CGCTTCGGCG  ACAAGCGAGT  CATCGACAGT  300
301   CCCATCACCG  AGTCTGGATT  CTGCGGTCTC  ACTGTCGGCG  CCGCATTGGC  GGGTCTGCAC  360
361   CCCGTCTGCG  AGTTCATGAC  CTTCAACTTC  GCTATGCAAG  CCATTGATCA  AATCATCAAC  420
421   TCCGCCGCAA  AGACACATTA  CATGTCTGGA  GGCATCCAAC  CCTGCAACAT  CACCTTCCGT  480
481   GGGCCCAACG  GTTTCGCCGC  CGGTGTGGCT  GCTCAGCACT  CCCAGGACTA  CTCGGCGTGG  540
541   TACGGCTCTA  TCCCAGGTCT  CAAGGTCGTC  GCGCCATACT  CCGCAGAGGA  CGCCAAGGGT  600
601   CTGCTCAAAG  CTGCCATTCG  CGATCCTAAC  CCGGTGTGTG  TGCTCGAGAA  CGAGCTCCTT  660
661   TACGGTCTCT  CCTTCCCCAT  GAGCGAAGAG  GCGCAAAGCG  ACGACTTTGT  CATTCCGTTC  720
721   GGCAAAGCCA  AAATCGAGCG  CCCCGGAAAG  GATCTCACCA  TCGTCACCCT  CTCCCGCTGC  780
781   GTCGGACAAT  CCCTCCAAGC  CGCCGAGATC  CTCAAGAGCA  AGTACGGAGT  CGAAGCAGAA  840
841   GTCATCAACC  TCCGCAGCAT  CAAGCCTCTC  GACGTCGAAG  CGATTGTCAA  ATCCGTCAAG  900
901   AAGACCGGCC  ACATGATGGC  GGTGGAGTCG  GGCTTCCCCA  GCTTCGGCGT  GGGTGCCGAG  960
961   ATCATCGCCC  TCACGGCCGA  GTACGCTTTC  GATTACCTGG  AGGCACCTCC  TGTTCGCGTC  1020
1021  ACGGGCGCGG  AGGTCCCGAC  TCCGTATGCG  CAGAAGTTAG  AGGAGATGGC  CTTCCCGACG  1080
1081  GAGCAGCTGA  TTGCGGATTA  TGCGGCCAAG  TTGCTTCGCG  TATAG  1125

▼ KEYWORD

ID
Family
Complete proteome
Glycolysis
Mitochondrion
Oxidoreductase
Pyruvate
Reference proteome
Thiamine pyrophosphate
Transit peptide

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
Mitochondrial matrix
Molecular Function
Pyruvate dehydrogenase (acetyl-transferring) activity
Biological Process
Acetyl-CoA biosynthetic process from pyruvate
Biological Process
Glycolytic process

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Dos-0928Dothistroma septosporum89.30.0 699
LLPS-Pytr-1489Pyrenophora triticirepentis86.130.0 658
LLPS-Pyt-1228Pyrenophora teres86.130.0 659
LLPS-Phn-0656Phaeosphaeria nodorum85.60.0 652
LLPS-Lem-1041Leptosphaeria maculans84.570.0 657
LLPS-Cog-0312Colletotrichum gloeosporioides84.020.0 595
LLPS-Fus-0274Fusarium solani83.670.0 599
LLPS-Mao-0241Magnaporthe oryzae81.340.0 587
LLPS-Asfu-0580Aspergillus fumigatus79.310.0 615
LLPS-Nef-1592Neosartorya fischeri79.050.0 614
LLPS-Blg-0945Blumeria graminis78.610.0 605
LLPS-Asn-1502Aspergillus nidulans77.720.0 602
LLPS-Cogr-0252Colletotrichum graminicola77.660.0 587
LLPS-Map-1044Magnaporthe poae77.560.0 583
LLPS-Ved-1083Verticillium dahliae77.510.0 598
LLPS-Coo-1348Colletotrichum orbiculare77.110.0 599
LLPS-Fuo-0519Fusarium oxysporum76.680.0 601
LLPS-Asc-0590Aspergillus clavatus76.660.0 599
LLPS-Ast-0263Aspergillus terreus76.60.0 594
LLPS-Asni-1357Aspergillus niger76.60.0 595
LLPS-Gag-0235Gaeumannomyces graminis76.580.0 582
LLPS-Aso-0389Aspergillus oryzae76.330.0 590
LLPS-Asf-0871Aspergillus flavus76.330.0 590
LLPS-Fuv-0962Fusarium verticillioides76.170.0 593
LLPS-Beb-0595Beauveria bassiana75.650.0 596
LLPS-Nec-0425Neurospora crassa75.130.0 585
LLPS-Trv-1486Trichoderma virens74.80.0 590
LLPS-Trr-0528Trichoderma reesei74.350.0 582
LLPS-Tum-1131Tuber melanosporum72.190.0 551
LLPS-Sac-0906Saccharomyces cerevisiae68.478e-166 476
LLPS-Yal-0945Yarrowia lipolytica67.684e-165 473
LLPS-Asg-0855Ashbya gossypii67.587e-165 473
LLPS-Usm-1335Ustilago maydis67.261e-166 480
LLPS-Scj-0237Schizosaccharomyces japonicus66.292e-165 475
LLPS-Spr-0929Sporisorium reilianum65.982e-166 479
LLPS-Mel-1123Melampsora laricipopulina65.923e-168 483
LLPS-Nia-2400Nicotiana attenuata65.731e-148 432
LLPS-Orbr-2089Oryza brachyantha65.611e-143 419
LLPS-Mal-1647Mandrillus leucophaeus65.65e-134 394
LLPS-Kop-1116Komagataella pastoris65.341e-164 473
LLPS-Fia-0917Ficedula albicollis65.292e-146 426
LLPS-Cis-0941Ciona savignyi65.143e-150 436
LLPS-Brn-2945Brassica napus64.765e-148 431
LLPS-Orgl-0360Oryza glumaepatula64.652e-141 414
LLPS-Viv-1849Vitis vinifera64.532e-147 429
LLPS-Sol-1444Solanum lycopersicum64.492e-145 424
LLPS-Art-0386Arabidopsis thaliana64.481e-147 430
LLPS-Put-0225Puccinia triticina64.446e-163 470
LLPS-Ors-2424Oryza sativa64.331e-140 412
LLPS-Ori-2128Oryza indica64.331e-140 412
LLPS-Orni-1893Oryza nivara64.331e-140 412
LLPS-Anp-1676Anas platyrhynchos64.313e-124 367
LLPS-Lep-1309Leersia perrieri64.222e-145 424
LLPS-Brd-0039Brachypodium distachyon64.175e-145 423
LLPS-Orm-2006Oryza meridionalis64.011e-133 415
LLPS-Org-2017Oryza glaberrima64.012e-141 414
LLPS-Lac-0422Latimeria chalumnae64.015e-145 424
LLPS-Orb-0758Oryza barthii64.011e-141 414
LLPS-Sah-2310Sarcophilus harrisii63.974e-118 350
LLPS-Abg-0645Absidia glauca63.918e-160 461
LLPS-Arl-0422Arabidopsis lyrata63.912e-147 429
LLPS-Cus-0073Cucumis sativus63.918e-146 425
LLPS-Miv-1314Microbotryum violaceum63.95e-163 469
LLPS-Sot-0156Solanum tuberosum63.863e-146 426
LLPS-Sem-0095Selaginella moellendorffii63.783e-139 407
LLPS-Scc-0925Schizosaccharomyces cryophilus63.723e-157 454
LLPS-Cae-0928Caenorhabditis elegans63.722e-146 426
LLPS-Orr-2417Oryza rufipogon63.696e-141 413
LLPS-Xet-1737Xenopus tropicalis63.695e-146 425
LLPS-Tra-2201Triticum aestivum63.611e-145 424
LLPS-Orp-1876Oryza punctata63.552e-142 416
LLPS-Meg-0364Meleagris gallopavo63.536e-148 429
LLPS-Php-1170Physcomitrella patens63.462e-136 401
LLPS-Hov-0812Hordeum vulgare63.411e-143 420
LLPS-Tru-1440Triticum urartu63.283e-127 395
LLPS-Zem-0254Zea mays63.246e-143 418
LLPS-Sob-0686Sorghum bicolor63.243e-143 419
LLPS-Tag-0067Taeniopygia guttata63.225e-145 422
LLPS-Gaga-0775Gallus gallus63.224e-147 428
LLPS-Bro-2833Brassica oleracea63.051e-146 427
LLPS-Brr-2562Brassica rapa63.053e-147 429
LLPS-Hea-1522Helianthus annuus63.058e-149 433
LLPS-Gor-1337Gossypium raimondii63.02e-146 426
LLPS-Mae-0525Manihot esculenta63.04e-145 423
LLPS-Mua-1285Musa acuminata62.933e-141 415
LLPS-Dar-3892Danio rerio62.924e-148 430
LLPS-Phv-0014Phaseolus vulgaris62.696e-143 417
LLPS-Scp-0451Schizosaccharomyces pombe62.619e-157 452
LLPS-Pes-0018Pelodiscus sinensis62.596e-121 358
LLPS-Crn-0413Cryptococcus neoformans62.534e-161 465
LLPS-Dio-1614Dipodomys ordii62.56e-148 429
LLPS-Fud-2926Fukomys damarensis62.59e-147 426
LLPS-Gas-0659Galdieria sulphuraria62.429e-135 397
LLPS-Amt-1535Amborella trichopoda62.314e-142 416
LLPS-Cii-2317Ciona intestinalis62.315e-141 412
LLPS-Myl-0782Myotis lucifugus62.22e-145 423
LLPS-Pot-0702Populus trichocarpa62.138e-147 427
LLPS-Via-0990Vigna angularis62.083e-142 416
LLPS-Dac-0455Daucus carota62.031e-139 420
LLPS-Anc-1607Anolis carolinensis62.018e-145 422
LLPS-Chr-1101Chlamydomonas reinhardtii61.994e-141 412
LLPS-Sei-0880Setaria italica61.983e-145 424
LLPS-Bot-3811Bos taurus61.885e-149 434
LLPS-Pof-1054Poecilia formosa61.76e-146 425
LLPS-Xim-1462Xiphophorus maculatus61.78e-145 422
LLPS-Coc-1555Corchorus capsularis61.468e-123 364
LLPS-Chc-1173Chondrus crispus61.48e-138 404
LLPS-Orl-1106Oryzias latipes61.42e-146 427
LLPS-Tut-1770Tursiops truncatus61.295e-146 425
LLPS-Glm-0952Glycine max61.246e-143 417
LLPS-Thc-1297Theobroma cacao61.168e-146 425
LLPS-Met-2102Medicago truncatula61.142e-141 414
LLPS-Cym-0437Cyanidioschyzon merolae61.138e-139 408
LLPS-Mod-0016Monodelphis domestica61.065e-147 427
LLPS-Asm-2200Astyanax mexicanus60.796e-139 407
LLPS-Aon-2246Aotus nancymaae60.771e-146 427
LLPS-Leo-1063Lepisosteus oculatus60.722e-151 439
LLPS-Prp-1143Prunus persica60.411e-143 420
LLPS-Ten-0463Tetraodon nigroviridis60.392e-148 431
LLPS-Osl-0787Ostreococcus lucimarinus60.191e-137 402
LLPS-Orn-1247Oreochromis niloticus60.111e-149 434
LLPS-Gaa-1536Gasterosteus aculeatus59.777e-145 422
LLPS-Ova-3199Ovis aries59.555e-148 430
LLPS-Ran-0665Rattus norvegicus59.552e-148 434
LLPS-Mum-3456Mus musculus59.552e-149 434
LLPS-Scf-0736Scleropages formosus59.383e-147 428
LLPS-Icp-2282Ictalurus punctatus59.382e-147 429
LLPS-Mam-3252Macaca mulatta59.271e-147 429
LLPS-Caf-0260Canis familiaris59.273e-149 433
LLPS-Poa-3210Pongo abelii59.277e-148 430
LLPS-Cap-0239Cavia porcellus59.274e-148 431
LLPS-Eqc-3286Equus caballus59.276e-151 437
LLPS-Nol-0631Nomascus leucogenys59.278e-148 430
LLPS-Man-3582Macaca nemestrina59.279e-148 429
LLPS-Hos-0234Homo sapiens59.279e-148 429
LLPS-Pat-1593Pan troglodytes59.279e-148 429
LLPS-Orc-1675Oryctolagus cuniculus59.276e-148 430
LLPS-Otg-0633Otolemur garnettii59.272e-150 437
LLPS-Paa-3235Papio anubis59.271e-147 429
LLPS-Cea-1229Cercocebus atys59.279e-148 429
LLPS-Maf-0765Macaca fascicularis59.279e-148 429
LLPS-Chs-0009Chlorocebus sabaeus59.279e-148 429
LLPS-Gog-0265Gorilla gorilla59.279e-148 429
LLPS-Sus-1285Sus scrofa59.12e-147 429
LLPS-Mea-3784Mesocricetus auratus59.12e-150 436
LLPS-Cas-2318Carlito syrichta58.991e-148 432
LLPS-Fec-2510Felis catus58.997e-148 430
LLPS-Rhb-3943Rhinopithecus bieti58.993e-146 426
LLPS-Urm-1373Ursus maritimus58.823e-149 433
LLPS-Aim-2010Ailuropoda melanoleuca58.824e-149 433
LLPS-Mup-0722Mustela putorius furo58.715e-149 433
LLPS-Caj-1818Callithrix jacchus58.717e-147 427
LLPS-Loa-2906Loxodonta africana58.541e-146 427
LLPS-Ict-0196Ictidomys tridecemlineatus58.432e-147 429
LLPS-Scm-0815Scophthalmus maximus57.782e-144 421
LLPS-Drm-0401Drosophila melanogaster57.436e-138 405
LLPS-Pap-1107Pan paniscus56.467e-137 401
LLPS-Vir-0140Vigna radiata54.637e-105 320