• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Yal-1080
YALI0_B15598g

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: 6-phosphogluconate dehydrogenase, decarboxylating
Gene Name: YALI0_B15598g
Ensembl Gene: YALI0_B15598g
Ensembl Protein: CAG83189
Organism: Yarrowia lipolytica
Taxa ID: 284591
LLPS Type: Client


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Nucleolus, Centrosome/Spindle pole body, OthersPredicted from orthologs(View)

▼ FUNCTION

Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.

▼ CROSS REFERENCE

DatabaseNucleotide IDProtein ID
EnsemblCAG83189CAG83189
UniProtQ6CEH4, Q6CEH4_YARLI
GeneBankCR382128CAG83189.1
RefSeqXM_500938.1XP_500938.1

▼ SEQUENCE

Protein Sequence (FASTA)
1     MTDTSNIKPV  ADIALIGLAV  MGQNLILNMA  DHGYEVVAYN  RTTSKVDHFL  ENEAKGKSII  60
61    GAHSIKELCA  LLKRPRRIIL  LVKAGAAVDS  FIEQLLPYLD  KGDIIIDGGN  SHFPDSNRRY  120
121   EELNEKGILF  VGSGVSGGEE  GARYGPSIMP  GGNKEAWPHI  KKIFQDISAK  ADGEPCCDWV  180
181   GDAGAGHFVK  MVHNGIEYGD  MQLICEAYDL  MKRGAGFTNE  EIGDVFAKWN  NGILDSFLIE  240
241   ITRDIFKYDD  GSGTPLVEKI  SDTAGQKGTG  KWTAINALDL  GMPVTLIGEA  VFARCLSALK  300
301   QERVRASKVL  DGPEPVKFTG  DKKEFVDQLE  QALYASKIIS  YAQGFMLIRE  AAKTYGWELN  360
361   NAGIALMWRG  GCIIRSVFLA  DITKAYRQDP  NLENLLFNDF  FKNAISKANP  SWRATVAKAV  420
421   TWGVPTPAFA  SALAFYDGYR  SAKLPANLLQ  AQRDYFGAHT  YQLLDGDGKW  IHTNWTGRGG  480
481   EVSSSTYDA  489
Nucleotide CDS Sequence (FASTA)
1     ATGACTGACA  CTTCAAACAT  CAAGCCTGTC  GCTGACATTG  CCCTCATCGG  TCTCGCCGTC  60
61    ATGGGCCAGA  ACCTGATCCT  CAACATGGCC  GACCACGGCT  ACGAGGTTGT  TGCCTACAAC  120
121   CGAACCACCT  CCAAGGTCGA  CCACTTCCTC  GAGAACGAGG  CCAAGGGAAA  GTCCATTATT  180
181   GGTGCTCACT  CTATCAAGGA  GCTGTGTGCT  CTGCTGAAGC  GACCCCGACG  AATCATTCTG  240
241   CTCGTTAAGG  CCGGTGCTGC  TGTCGATTCT  TTCATCGAAC  AGCTCCTGCC  CTATCTCGAT  300
301   AAGGGTGATA  TCATCATTGA  CGGTGGTAAC  TCCCACTTCC  CCGACTCCAA  CCGACGATAC  360
361   GAGGAGCTTA  ACGAGAAGGG  AATCCTCTTT  GTTGGTTCCG  GTGTTTCCGG  CGGTGAGGAG  420
421   GGTGCCCGAT  ACGGTCCCTC  CATCATGCCC  GGTGGAAACA  AGGAGGCCTG  GCCCCACATT  480
481   AAGAAGATTT  TCCAGGACAT  CTCTGCTAAG  GCTGATGGTG  AGCCCTGCTG  TGACTGGGTC  540
541   GGTGACGCTG  GTGCCGGCCA  CTTTGTCAAG  ATGGTTCACA  ACGGTATTGA  GTATGGTGAC  600
601   ATGCAGCTTA  TCTGCGAGGC  TTACGACCTC  ATGAAGCGAG  GTGCTGGTTT  CACCAATGAG  660
661   GAGATTGGAG  ACGTTTTCGC  CAAGTGGAAC  AACGGTATCC  TCGACTCCTT  CCTCATTGAG  720
721   ATCACCCGAG  ACATCTTCAA  GTACGACGAC  GGCTCTGGAA  CTCCTCTCGT  TGAGAAGATC  780
781   TCCGACACTG  CTGGCCAGAA  GGGTACTGGA  AAGTGGACCG  CTATCAACGC  TCTTGACCTT  840
841   GGTATGCCCG  TCACCCTGAT  CGGTGAGGCC  GTCTTCGCTC  GATGCCTTTC  TGCCCTCAAG  900
901   CAGGAGCGTG  TCCGAGCTTC  CAAGGTTCTT  GATGGCCCCG  AGCCCGTCAA  GTTCACTGGT  960
961   GACAAGAAGG  AGTTTGTCGA  CCAGCTCGAG  CAGGCCCTTT  ACGCCTCCAA  GATCATCTCT  1020
1021  TACGCCCAGG  GTTTCATGCT  TATCCGAGAG  GCCGCCAAGA  CCTACGGCTG  GGAGCTCAAC  1080
1081  AACGCCGGTA  TTGCCCTCAT  GTGGCGAGGT  GGTTGCATCA  TCCGATCCGT  CTTCCTTGCT  1140
1141  GACATCACCA  AGGCTTACCG  ACAGGACCCC  AACCTCGAGA  ACCTGCTGTT  CAACGACTTC  1200
1201  TTCAAGAACG  CCATCTCCAA  GGCCAACCCC  TCTTGGCGAG  CTACCGTGGC  CAAGGCTGTC  1260
1261  ACCTGGGGTG  TTCCCACTCC  CGCCTTTGCC  TCGGCTCTGG  CTTTCTACGA  CGGTTACCGA  1320
1321  TCTGCCAAGC  TCCCCGCTAA  CCTGCTCCAG  GCCCAGCGAG  ACTACTTCGG  CGCCCACACC  1380
1381  TACCAGCTCC  TCGATGGTGA  TGGAAAGTGG  ATCCACACCA  ACTGGACCGG  CCGAGGTGGT  1440
1441  GAGGTTTCTT  CTTCCACTTA  CGATGCTTAA  1470

▼ KEYWORD

ID
Family
Complete proteome
Gluconate utilization
NADP
Oxidoreductase
Pentose shunt
Reference proteome

▼ GENE ONTOLOGY

ID
Classification
Description
Molecular Function
NADP binding
Molecular Function
Phosphogluconate dehydrogenase (decarboxylating) activity
Biological Process
D-gluconate metabolic process
Biological Process
Pentose-phosphate shunt

▼ KEGG


▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Asg-0427Ashbya gossypii76.750.0 756
LLPS-Kop-0424Komagataella pastoris76.580.0 757
LLPS-Asc-1076Aspergillus clavatus76.540.0 749
LLPS-Nef-1247Neosartorya fischeri76.340.0 751
LLPS-Asfu-1566Aspergillus fumigatus76.130.0 747
LLPS-Asni-1399Aspergillus niger75.610.0 747
LLPS-Asn-1247Aspergillus nidulans75.360.0 747
LLPS-Aso-0105Aspergillus oryzae75.260.0 740
LLPS-Asf-1328Aspergillus flavus75.260.0 740
LLPS-Sac-0953Saccharomyces cerevisiae74.490.0 739
LLPS-Ast-0719Aspergillus terreus74.320.0 720
LLPS-Abg-0247Absidia glauca72.710.0 714
LLPS-Tum-0204Tuber melanosporum72.643e-159 461
LLPS-Dos-0915Dothistroma septosporum72.510.0 713
LLPS-Miv-0284Microbotryum violaceum72.450.0 724
LLPS-Nec-1016Neurospora crassa72.390.0 709
LLPS-Zyt-0481Zymoseptoria tritici72.30.0 716
LLPS-Beb-1037Beauveria bassiana72.240.0 710
LLPS-Spr-1070Sporisorium reilianum72.190.0 716
LLPS-Usm-0912Ustilago maydis71.980.0 717
LLPS-Put-1271Puccinia triticina71.720.0 729
LLPS-Pug-1421Puccinia graminis71.720.0 731
LLPS-Scj-0416Schizosaccharomyces japonicus71.720.0 711
LLPS-Trv-1316Trichoderma virens71.630.0 697
LLPS-Trr-1324Trichoderma reesei71.430.0 700
LLPS-Mao-0687Magnaporthe oryzae71.310.0 701
LLPS-Phn-0995Phaeosphaeria nodorum71.280.0 700
LLPS-Lem-0837Leptosphaeria maculans71.20.0 708
LLPS-Cii-1328Ciona intestinalis71.182e-73 236
LLPS-Fus-0777Fusarium solani71.170.0 701
LLPS-Blg-1195Blumeria graminis71.080.0 699
LLPS-Mel-0770Melampsora laricipopulina71.020.0 718
LLPS-Scp-1362Schizosaccharomyces pombe70.820.0 691
LLPS-Cog-0181Colletotrichum gloeosporioides70.790.0 674
LLPS-Gog-2489Gorilla gorilla70.670.0 523
LLPS-Pyt-1618Pyrenophora teres70.610.0 697
LLPS-Fuo-0069Fusarium oxysporum70.550.0 697
LLPS-Fuv-0452Fusarium verticillioides70.350.0 696
LLPS-Cap-3268Cavia porcellus70.182e-130 387
LLPS-Cogr-1544Colletotrichum graminicola69.90.0 692
LLPS-Map-1362Magnaporthe poae69.880.0 688
LLPS-Gag-1467Gaeumannomyces graminis69.670.0 691
LLPS-Crn-1088Cryptococcus neoformans69.40.0 690
LLPS-Pytr-0190Pyrenophora triticirepentis69.310.0 681
LLPS-Cis-0708Ciona savignyi69.310.0 665
LLPS-Cea-0694Cercocebus atys69.170.0 654
LLPS-Scc-0746Schizosaccharomyces cryophilus69.060.0 673
LLPS-Paa-0744Papio anubis68.960.0 651
LLPS-Maf-2341Macaca fascicularis68.960.0 651
LLPS-Icp-2167Ictalurus punctatus68.960.0 672
LLPS-Coo-1492Colletotrichum orbiculare68.920.0 676
LLPS-Ict-4488Ictidomys tridecemlineatus68.750.0 653
LLPS-Gaga-3204Gallus gallus68.750.0 671
LLPS-Man-4450Macaca nemestrina68.750.0 644
LLPS-Loa-0119Loxodonta africana68.750.0 652
LLPS-Pat-4847Pan troglodytes68.750.0 666
LLPS-Hos-2007Homo sapiens68.750.0 667
LLPS-Lac-3265Latimeria chalumnae68.750.0 655
LLPS-Dio-1838Dipodomys ordii68.750.0 650
LLPS-Mum-4313Mus musculus68.750.0 653
LLPS-Asm-2496Astyanax mexicanus68.750.0 668
LLPS-Caj-2400Callithrix jacchus68.750.0 650
LLPS-Mup-2840Mustela putorius furo68.540.0 648
LLPS-Ova-3910Ovis aries68.490.0 622
LLPS-Bot-2896Bos taurus68.480.0 623
LLPS-Nol-4583Nomascus leucogenys68.40.0 666
LLPS-Gaa-3377Gasterosteus aculeatus68.40.0 668
LLPS-Eqc-3490Equus caballus68.330.0 647
LLPS-Fec-2836Felis catus68.330.0 649
LLPS-Scm-3459Scophthalmus maximus68.330.0 659
LLPS-Tar-0952Takifugu rubripes68.330.0 662
LLPS-Myl-2794Myotis lucifugus68.330.0 649
LLPS-Orl-2730Oryzias latipes68.330.0 661
LLPS-Mam-3788Macaca mulatta68.30.0 633
LLPS-Fia-2616Ficedula albicollis68.230.0 651
LLPS-Ved-1598Verticillium dahliae68.140.0 678
LLPS-Orn-3411Oreochromis niloticus68.120.0 660
LLPS-Aim-3862Ailuropoda melanoleuca68.120.0 646
LLPS-Orc-3180Oryctolagus cuniculus68.070.0 639
LLPS-Xim-3259Xiphophorus maculatus67.980.0 664
LLPS-Fud-3632Fukomys damarensis67.920.0 646
LLPS-Pap-1795Pan paniscus67.870.0 645
LLPS-Urm-2561Ursus maritimus67.870.0 629
LLPS-Anc-0204Anolis carolinensis67.780.0 652
LLPS-Caf-4663Canis familiaris67.710.0 642
LLPS-Aon-2179Aotus nancymaae67.710.0 635
LLPS-Mea-2069Mesocricetus auratus67.710.0 644
LLPS-Pof-1290Poecilia formosa67.70.0 658
LLPS-Poa-3637Pongo abelii67.651e-57 202
LLPS-Cas-3458Carlito syrichta67.630.0 643
LLPS-Ten-3610Tetraodon nigroviridis67.50.0 659
LLPS-Meg-1443Meleagris gallopavo67.470.0 625
LLPS-Mod-2566Monodelphis domestica67.220.0 639
LLPS-Dar-1631Danio rerio67.080.0 654
LLPS-Leo-0480Lepisosteus oculatus67.080.0 652
LLPS-Scf-3877Scleropages formosus66.670.0 628
LLPS-Drm-0495Drosophila melanogaster66.60.0 642
LLPS-Sus-4348Sus scrofa66.250.0 623
LLPS-Mal-0334Mandrillus leucophaeus65.570.0 608
LLPS-Cae-1999Caenorhabditis elegans65.490.0 647
LLPS-Chs-2158Chlorocebus sabaeus65.481e-140 414
LLPS-Gas-0161Galdieria sulphuraria65.140.0 640
LLPS-Tag-2085Taeniopygia guttata64.882e-140 413
LLPS-Sah-1865Sarcophilus harrisii63.861e-169 504
LLPS-Ora-3548Ornithorhynchus anatinus63.670.0 575
LLPS-Otg-2276Otolemur garnettii62.660.0 593
LLPS-Cym-0665Cyanidioschyzon merolae61.60.0 590
LLPS-Xet-0141Xenopus tropicalis58.330.0 558
LLPS-Rhb-0360Rhinopithecus bieti55.018e-162 473
LLPS-Tru-1428Triticum urartu52.72e-166 485
LLPS-Coc-1139Corchorus capsularis50.967e-147 436
LLPS-Mae-1098Manihot esculenta50.858e-147 436
LLPS-Phv-0523Phaseolus vulgaris50.532e-146 435
LLPS-Viv-1304Vitis vinifera50.524e-147 437
LLPS-Via-2321Vigna angularis50.521e-146 437
LLPS-Sei-1699Setaria italica50.413e-104 324
LLPS-Prp-0058Prunus persica50.215e-143 427
LLPS-Sem-1617Selaginella moellendorffii50.212e-146 435
LLPS-Php-1938Physcomitrella patens50.112e-150 446
LLPS-Cus-1172Cucumis sativus50.04e-145 432
LLPS-Thc-1579Theobroma cacao50.09e-144 429
LLPS-Met-1992Medicago truncatula49.96e-151 447
LLPS-Brd-1398Brachypodium distachyon49.891e-145 437
LLPS-Pot-2670Populus trichocarpa49.796e-143 426
LLPS-Orm-0356Oryza meridionalis49.681e-145 434
LLPS-Arl-2174Arabidopsis lyrata49.681e-142 426
LLPS-Zem-1233Zea mays49.575e-144 429
LLPS-Brr-1620Brassica rapa49.473e-143 427
LLPS-Tra-0535Triticum aestivum49.472e-146 436
LLPS-Ori-1144Oryza indica49.422e-107 331
LLPS-Vir-1072Vigna radiata49.271e-142 426
LLPS-Orr-2013Oryza rufipogon49.262e-142 425
LLPS-Org-2060Oryza glaberrima49.262e-142 425
LLPS-Bro-1757Brassica oleracea49.262e-142 425
LLPS-Art-0948Arabidopsis thaliana49.267e-142 424
LLPS-Ors-0653Oryza sativa49.262e-142 425
LLPS-Nia-2477Nicotiana attenuata49.265e-144 429
LLPS-Orgl-2158Oryza glumaepatula49.262e-142 425
LLPS-Orb-2136Oryza barthii49.267e-141 424
LLPS-Orni-1042Oryza nivara49.262e-142 425
LLPS-Dac-0128Daucus carota49.263e-147 437
LLPS-Sob-1316Sorghum bicolor49.252e-142 425
LLPS-Gor-2622Gossypium raimondii49.062e-143 427
LLPS-Glm-0407Glycine max49.065e-148 440
LLPS-Sot-0347Solanum tuberosum49.047e-144 429
LLPS-Brn-0311Brassica napus48.952e-145 433
LLPS-Lep-0448Leersia perrieri48.942e-142 426
LLPS-Hov-0612Hordeum vulgare48.841e-143 432
LLPS-Orbr-0791Oryza brachyantha48.726e-142 424
LLPS-Hea-1824Helianthus annuus48.712e-137 412
LLPS-Sol-0720Solanum lycopersicum48.645e-143 427
LLPS-Orp-2321Oryza punctata48.517e-142 424
LLPS-Amt-0546Amborella trichopoda48.336e-141 421
LLPS-Osl-1060Ostreococcus lucimarinus48.162e-141 424
LLPS-Chr-0069Chlamydomonas reinhardtii47.752e-146 438
LLPS-Mua-2173Musa acuminata45.381e-128 389
LLPS-Scs-0629Sclerotinia sclerotiorum38.972e-31 128