• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Yal-0459
MON1

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Vacuolar fusion protein MON1
Gene Name: MON1, YALI0C06347g
Ensembl Gene: YALI0_C06347g
Ensembl Protein: CAG81815
Organism: Yarrowia lipolytica
Taxa ID: 284591
LLPS Type: LLPS regulator


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Stress granulePredicted from orthologs(View)

▼ FUNCTION

Required for multiple vacuole delivery pathways including the cytoplasm to vacuole transport (Cvt), autophagy, pexophagy and endocytosis.

▼ CROSS REFERENCE

DatabaseNucleotide IDProtein ID
EnsemblCAG81815CAG81815
UniProtQ6CCU8, MON1_YARLI
GeneBankCR382129CAG81815.1
RefSeqXM_501514.1XP_501514.1

▼ SEQUENCE

Protein Sequence (FASTA)
1     MEDGAKDDYI  KDIYRHASPN  ADTDSFLGSP  TVAIDSTLST  SNSLSNLNLD  TNDSSSSPPA  60
61    HNDDVPDIAE  VLQEMLATTE  LPSSTTDLDY  EPELDLVGGH  RRNLGQLNDY  GSPRADSFVS  120
121   LDPPSIGTEV  EQFLSKKKQF  FILSSAGKPI  YTLHGSDDVI  LGYLGVLQTV  VSAYQADESG  180
181   DNLMSFRAGK  TLVVVAVEGP  LILAAVSKIG  ESESQLRAQL  DVLYTQILST  LTKNQIHRIY  240
241   ANQSNFDLRN  LLQGTDVYLD  ALTREIVNGS  PSILLGALEP  LILRKSIREE  IDGVLLSCRT  300
301   PSLLYGLIVS  DSKLANVIRP  KKHSLHPPDL  ILLFSMLFNT  TSFRDGEHWV  PICLPKFNST  360
361   GFLYAYIHFF  SKSSALIQIS  ADKNAFFELR  EAKQQILSQM  EDKGLIKALE  RAEERGRFKP  420
421   VDVAVPMVRH  FLYKSRAHVQ  YVMPSYETHY  YEPHMQRGLL  TFYHQLHAQV  NSDSSRGSNN  480
481   GWRFMHLVRN  SCIGFAWITP  SFELYCVSGP  NVSRATLAAS  IHSIAKWVSQ  HRERLFVIGG  540
541   AVF  543
Nucleotide CDS Sequence (FASTA)
1     ATGGAAGACG  GCGCAAAAGA  TGACTACATC  AAGGACATCT  ACCGACACGC  GTCGCCCAAC  60
61    GCCGACACAG  ACTCCTTCCT  CGGCAGCCCC  ACCGTCGCCA  TCGACAGCAC  GCTGTCCACG  120
121   TCCAACTCTC  TCAGCAACTT  GAATCTCGAC  ACCAACGACA  GCAGCAGCTC  GCCACCAGCT  180
181   CACAATGACG  ACGTGCCAGA  CATTGCCGAG  GTGCTCCAGG  AAATGCTCGC  AACCACAGAA  240
241   CTGCCGTCGT  CCACAACGGA  TCTGGACTAC  GAGCCTGAGC  TGGACCTTGT  GGGAGGCCAC  300
301   CGGCGCAATC  TGGGCCAGCT  GAACGACTAC  GGCAGCCCCA  GGGCGGACTC  GTTTGTGTCC  360
361   CTGGACCCGC  CCAGCATCGG  AACCGAGGTC  GAGCAGTTTC  TCTCCAAGAA  AAAACAGTTT  420
421   TTCATCCTCT  CCTCGGCCGG  AAAACCCATC  TACACCCTGC  ACGGCTCGGA  CGACGTGATT  480
481   CTCGGCTACC  TGGGCGTGCT  ACAGACGGTG  GTGAGCGCCT  ACCAGGCCGA  CGAGTCCGGC  540
541   GACAACCTCA  TGTCCTTTCG  AGCAGGCAAG  ACCCTCGTAG  TTGTTGCGGT  CGAGGGACCT  600
601   CTGATCCTGG  CGGCCGTGTC  CAAAATTGGA  GAGAGTGAGA  GCCAACTCAG  AGCCCAGTTG  660
661   GACGTGCTGT  ACACCCAGAT  TCTAAGCACG  CTGACCAAGA  ACCAGATTCA  TCGAATCTAT  720
721   GCCAACCAGA  GCAACTTCGA  TCTAAGAAAC  CTCCTGCAGG  GCACCGACGT  CTATCTGGAT  780
781   GCTCTGACCC  GGGAAATCGT  CAACGGAAGC  CCCTCAATTC  TCCTGGGGGC  TCTTGAGCCG  840
841   CTGATCCTGC  GAAAGTCCAT  CAGAGAAGAG  ATTGATGGTG  TTCTTCTCAG  CTGCAGAACG  900
901   CCCTCGCTGC  TCTACGGACT  GATTGTCTCT  GACTCCAAGC  TCGCCAACGT  TATCCGTCCC  960
961   AAGAAACACT  CGCTACATCC  GCCGGACCTT  ATCTTGCTGT  TTAGCATGCT  TTTCAACACC  1020
1021  ACCTCCTTCC  GCGATGGAGA  GCACTGGGTG  CCCATTTGTC  TGCCCAAGTT  CAACTCCACC  1080
1081  GGCTTCCTCT  ATGCCTACAT  CCACTTCTTC  AGCAAGTCGT  CTGCCCTGAT  TCAAATCTCC  1140
1141  GCCGATAAGA  ATGCATTTTT  CGAGCTGCGT  GAAGCCAAGC  AGCAGATCCT  GTCGCAGATG  1200
1201  GAAGATAAGG  GTCTTATCAA  GGCTCTGGAA  CGTGCAGAGG  AGAGGGGTAG  GTTCAAGCCG  1260
1261  GTGGATGTGG  CGGTCCCCAT  GGTGAGGCAC  TTTCTGTACA  AGAGCCGAGC  ACACGTGCAG  1320
1321  TATGTTATGC  CGTCCTACGA  GACGCACTAC  TACGAACCGC  ACATGCAGCG  CGGGCTGCTA  1380
1381  ACGTTCTACC  ACCAGCTCCA  TGCTCAGGTG  AACAGTGACT  CGTCCCGTGG  CTCCAACAAT  1440
1441  GGGTGGAGGT  TTATGCACTT  GGTGCGTAAT  TCCTGCATTG  GGTTTGCGTG  GATAACCCCC  1500
1501  TCTTTTGAGC  TCTATTGTGT  ATCGGGACCT  AACGTGTCGC  GTGCCACGCT  AGCCGCCTCC  1560
1561  ATCCACTCGA  TTGCCAAATG  GGTCAGCCAG  CACCGCGAGC  GGCTATTTGT  TATTGGAGGG  1620
1621  GCGGTTTTCT  AG  1632

▼ KEYWORD

ID
Family
Autophagy
Complete proteome
Endosome
Membrane
Protein transport
Reference proteome
Transport
Vacuole

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
Fungal-type vacuole membrane
Cellular Component
Mon1-Ccz1 complex
Cellular Component
Multivesicular body membrane
Biological Process
Autophagy
Biological Process
Protein transport

▼ KEGG


▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Tum-1271Tuber melanosporum53.242e-154 462
LLPS-Pytr-1196Pyrenophora triticirepentis46.532e-80 268
LLPS-Dos-1618Dothistroma septosporum46.062e-126 384
LLPS-Pyt-1215Pyrenophora teres46.04e-122 380
LLPS-Scs-0394Sclerotinia sclerotiorum45.876e-88 290
LLPS-Phn-0883Phaeosphaeria nodorum45.832e-79 261
LLPS-Fus-1004Fusarium solani45.561e-116 363
LLPS-Ved-1562Verticillium dahliae45.311e-121 377
LLPS-Lem-1614Leptosphaeria maculans45.293e-119 375
LLPS-Aso-1541Aspergillus oryzae44.931e-120 375
LLPS-Cog-0700Colletotrichum gloeosporioides44.653e-116 363
LLPS-Ast-1509Aspergillus terreus44.287e-88 288
LLPS-Asc-1649Aspergillus clavatus44.245e-115 361
LLPS-Coo-1061Colletotrichum orbiculare44.244e-116 363
LLPS-Fuo-1459Fusarium oxysporum44.086e-116 363
LLPS-Fuv-0794Fusarium verticillioides43.855e-115 360
LLPS-Trv-1079Trichoderma virens43.753e-114 358
LLPS-Cogr-1327Colletotrichum graminicola43.553e-115 361
LLPS-Trr-1583Trichoderma reesei43.521e-114 359
LLPS-Gag-0917Gaeumannomyces graminis43.093e-109 346
LLPS-Zyt-1520Zymoseptoria tritici43.058e-104 331
LLPS-Asf-1312Aspergillus flavus42.893e-119 370
LLPS-Nef-0120Neosartorya fischeri42.864e-87 286
LLPS-Mao-1276Magnaporthe oryzae42.533e-109 346
LLPS-Beb-0166Beauveria bassiana41.363e-109 345
LLPS-Asn-1102Aspergillus nidulans40.961e-105 337
LLPS-Asni-1227Aspergillus niger39.698e-108 343
LLPS-Nec-0009Neurospora crassa39.671e-107 343
LLPS-Blg-0931Blumeria graminis38.571e-109 342
LLPS-Abg-1308Absidia glauca37.411e-94 304
LLPS-Sac-0195Saccharomyces cerevisiae36.861e-75 258
LLPS-Asfu-0291Aspergillus fumigatus35.541e-39 149
LLPS-Cus-0652Cucumis sativus35.543e-42 162
LLPS-Cii-2265Ciona intestinalis34.889e-83 271
LLPS-Miv-1593Microbotryum violaceum33.817e-75 262
LLPS-Anp-0797Anas platyrhynchos33.666e-73 246
LLPS-Fia-0408Ficedula albicollis33.424e-71 245
LLPS-Tag-1115Taeniopygia guttata33.421e-71 245
LLPS-Gaga-3380Gallus gallus33.421e-71 245
LLPS-Asm-3152Astyanax mexicanus33.242e-59 211
LLPS-Meg-2257Meleagris gallopavo33.173e-69 238
LLPS-Chr-1677Chlamydomonas reinhardtii33.13e-36 148
LLPS-Mel-0593Melampsora laricipopulina33.016e-66 226
LLPS-Sot-1966Solanum tuberosum33.016e-28 119
LLPS-Lac-1153Latimeria chalumnae32.933e-72 247
LLPS-Orl-2467Oryzias latipes32.932e-73 249
LLPS-Crn-0894Cryptococcus neoformans32.861e-68 238
LLPS-Leo-1402Lepisosteus oculatus32.859e-71 242
LLPS-Cis-1705Ciona savignyi32.783e-75 251
LLPS-Asg-0839Ashbya gossypii32.712e-67 234
LLPS-Kop-1368Komagataella pastoris32.66e-76 257
LLPS-Sus-2991Sus scrofa32.431e-70 244
LLPS-Bot-4843Bos taurus32.434e-71 244
LLPS-Ova-3539Ovis aries32.439e-70 242
LLPS-Fud-2144Fukomys damarensis32.211e-75 256
LLPS-Pes-2946Pelodiscus sinensis32.29e-63 218
LLPS-Fec-2777Felis catus32.183e-71 244
LLPS-Caf-1801Canis familiaris32.182e-71 244
LLPS-Anc-0134Anolis carolinensis32.185e-74 251
LLPS-Cas-1896Carlito syrichta32.184e-71 244
LLPS-Ora-2793Ornithorhynchus anatinus32.185e-71 243
LLPS-Mup-3774Mustela putorius furo32.183e-71 244
LLPS-Dio-0893Dipodomys ordii32.083e-72 247
LLPS-Orn-3456Oreochromis niloticus31.965e-69 237
LLPS-Ten-3040Tetraodon nigroviridis31.952e-67 233
LLPS-Tar-3351Takifugu rubripes31.952e-73 249
LLPS-Xim-1467Xiphophorus maculatus31.952e-70 241
LLPS-Urm-0278Ursus maritimus31.937e-70 240
LLPS-Otg-1033Otolemur garnettii31.935e-71 243
LLPS-Scf-0214Scleropages formosus31.811e-72 247
LLPS-Gaa-3961Gasterosteus aculeatus31.711e-70 241
LLPS-Sah-0511Sarcophilus harrisii31.685e-69 238
LLPS-Myl-0884Myotis lucifugus31.683e-66 231
LLPS-Ere-0595Erinaceus europaeus31.658e-66 229
LLPS-Aim-3895Ailuropoda melanoleuca31.625e-63 222
LLPS-Xet-2312Xenopus tropicalis31.492e-71 244
LLPS-Pof-0906Poecilia formosa31.462e-66 230
LLPS-Mod-3214Monodelphis domestica31.442e-68 236
LLPS-Scp-0259Schizosaccharomyces pombe31.391e-64 225
LLPS-Tut-0905Tursiops truncatus31.364e-56 201
LLPS-Icp-1841Ictalurus punctatus31.282e-63 223
LLPS-Scm-1514Scophthalmus maximus31.227e-71 242
LLPS-Loa-1994Loxodonta africana31.193e-61 217
LLPS-Drm-1872Drosophila melanogaster31.124e-62 219
LLPS-Cap-4443Cavia porcellus31.031e-72 250
LLPS-Aon-2777Aotus nancymaae31.021e-71 247
LLPS-Caj-0998Callithrix jacchus31.022e-72 249
LLPS-Ran-4102Rattus norvegicus30.862e-72 247
LLPS-Man-0596Macaca nemestrina30.614e-71 246
LLPS-Hos-4955Homo sapiens30.612e-71 247
LLPS-Pap-4458Pan paniscus30.612e-71 247
LLPS-Pat-2823Pan troglodytes30.612e-71 247
LLPS-Rhb-2183Rhinopithecus bieti30.612e-71 246
LLPS-Eqc-1300Equus caballus30.611e-72 248
LLPS-Poa-4316Pongo abelii30.612e-72 247
LLPS-Nol-0630Nomascus leucogenys30.613e-71 246
LLPS-Cea-0712Cercocebus atys30.612e-71 246
LLPS-Chs-3872Chlorocebus sabaeus30.613e-71 246
LLPS-Maf-3708Macaca fascicularis30.614e-71 246
LLPS-Paa-0428Papio anubis30.613e-71 246
LLPS-Mal-2933Mandrillus leucophaeus30.612e-71 246
LLPS-Dar-4245Danio rerio30.498e-65 226
LLPS-Orc-2557Oryctolagus cuniculus30.411e-73 250
LLPS-Mam-3455Macaca mulatta30.413e-72 247
LLPS-Ict-2321Ictidomys tridecemlineatus30.413e-72 246
LLPS-Mea-3491Mesocricetus auratus30.412e-72 248
LLPS-Gog-1106Gorilla gorilla30.411e-71 247
LLPS-Mum-4059Mus musculus30.047e-71 243
LLPS-Met-2018Medicago truncatula29.328e-54 196
LLPS-Pug-1359Puccinia graminis29.257e-1888.2
LLPS-Lep-2140Leersia perrieri29.23e-58 209
LLPS-Bro-1227Brassica oleracea29.132e-53 196
LLPS-Spr-1312Sporisorium reilianum29.11e-35 146
LLPS-Sei-1637Setaria italica29.034e-56 204
LLPS-Orp-0765Oryza punctata28.975e-57 205
LLPS-Ors-2268Oryza sativa28.972e-57 207
LLPS-Org-2174Oryza glaberrima28.979e-57 205
LLPS-Brd-1982Brachypodium distachyon28.81e-57 208
LLPS-Scj-1075Schizosaccharomyces japonicus28.741e-56 203
LLPS-Tra-2094Triticum aestivum28.743e-58 209
LLPS-Scc-1194Schizosaccharomyces cryophilus28.681e-56 203
LLPS-Brr-0149Brassica rapa28.672e-49 185
LLPS-Arl-1174Arabidopsis lyrata28.62e-51 191
LLPS-Viv-2116Vitis vinifera28.545e-55 201
LLPS-Brn-3056Brassica napus28.416e-50 186
LLPS-Sem-2167Selaginella moellendorffii28.413e-53 195
LLPS-Prp-2200Prunus persica28.314e-54 198
LLPS-Orr-1354Oryza rufipogon28.283e-51 191
LLPS-Orb-1509Oryza barthii28.283e-51 191
LLPS-Orgl-1243Oryza glumaepatula28.284e-51 191
LLPS-Amt-1846Amborella trichopoda28.168e-48 181
LLPS-Usm-0627Ustilago maydis28.062e-32 137
LLPS-Art-2414Arabidopsis thaliana27.826e-52 192
LLPS-Sob-1195Sorghum bicolor27.821e-54 199
LLPS-Mua-1179Musa acuminata27.783e-53 196
LLPS-Mae-1239Manihot esculenta27.71e-55 203
LLPS-Tru-2015Triticum urartu27.595e-57 203
LLPS-Coc-1222Corchorus capsularis27.543e-55 201
LLPS-Phv-0278Phaseolus vulgaris27.522e-52 193
LLPS-Hea-1838Helianthus annuus27.522e-54 199
LLPS-Dac-0346Daucus carota27.345e-40 157
LLPS-Cae-1386Caenorhabditis elegans27.173e-42 162
LLPS-Thc-1645Theobroma cacao27.124e-54 198
LLPS-Glm-1638Glycine max27.116e-56 202
LLPS-Gor-1185Gossypium raimondii27.073e-48 181
LLPS-Nia-1321Nicotiana attenuata27.036e-55 198
LLPS-Php-1864Physcomitrella patens27.013e-53 197
LLPS-Sol-0963Solanum lycopersicum26.582e-50 188
LLPS-Via-0302Vigna angularis26.365e-54 197
LLPS-Pot-1260Populus trichocarpa26.352e-53 196
LLPS-Orbr-0355Oryza brachyantha26.154e-36 142
LLPS-Vir-0574Vigna radiata25.574e-40 157
LLPS-Zem-0471Zea mays24.548e-47 177
LLPS-Put-0067Puccinia triticina22.023e-22 104