• Disorder
  • Domain
  • PTM
  • Variation
  • Mutation
  • Interaction
  • Disease
  • Drug
  • Physicochemical
  • Function
  • Proteomics
  • Structure
  • Localization
  • Expression
  • Element
  • Methylation

LLPS-Xim-a280

Integrated Annotations

▼ OVERVIEW


Status: Unreviewed
Protein Name: Vacuolar protein sorting-associated protein 29; Vesicle protein sorting 29
Ensembl Gene: ENSXMAG00000024591.1
Ensembl Protein: ENSXMAP00000038796.1
Organism: Xiphophorus maculatus
Taxa ID: 8083
LLPS Type: Others


▼ PROPERTY



——— Disorder propensity (calculated by IUPred2A)

▼ Classification


Condensates:
CondensateEvidenceOrthologs
Postsynaptic densityPredicted from orthologs(View)

▼ FUNCTION


Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.

▼ SEQUENCE


Protein Sequence (FASTA)
1     MLVLVLGDLH  IPHRCNTLPA  KFKKLLVPGK  IQHILCTGNL  CTKESYDYLK  TLAGDVHIVR  60
61    GDFDENLNYP  EQKVVTVGQF  KIGLIHGHQV  IPWGDMASLA  LLQRQLDVDI  LISGHTHKFE  120
121   AFENENKFYI  NPGSATGAYN  ALERNIIPSF  VLMDIQASTV  VTYVYQLIGD  DVKVERIEYK  180
181   KS  182

▼ KEYWORD


ID
Family
Complete proteome
Protein transport
Reference proteome
Transport

▼ GENE ONTOLOGY


ID
Classification
Description
Cellular Component
Cytosol
Cellular Component
Retromer complex
Biological Process
Protein transport
Biological Process
Retrograde transport, endosome to Golgi

▼ KEGG



▼ ORTHOLOGY


DrLLPS IDOrganismIdentityE-valueScore
LLPS-Hos-a317Homo sapiens2e-127366undefined
LLPS-Mum-a317Mus musculus3e-128367undefined