• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Xim-3638

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Elongation factor 1-alpha
Ensembl Gene: ENSXMAG00000017149.2
Ensembl Protein: ENSXMAP00000038501.1
Organism: Xiphophorus maculatus
Taxa ID: 8083
LLPS Type: Client


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Nuclear speckle, Nucleolus, Neuronal granule, Chromatoid body, Postsynaptic densityPredicted from orthologs(View)

▼ FUNCTION

This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

▼ SEQUENCE

Protein Sequence (FASTA)
1     MGKEKLHINI  VVIGHVDSGK  STTTGHLIYK  CGGIDKRTIE  KFEKEAAEMG  KGSFKYAWVL  60
61    DKLKAERERG  ITIDISLWKF  ETSKYYVTII  DAPGHRDFIK  NMITGTSQAD  CAVLIVAAGV  120
121   GEFEAGISKN  GQTREHALLA  YTLGVKQLIV  GINKMDSTEP  NYSQKRYEEI  VKEVSTYIKK  180
181   IGYNPDTVAF  VPISGWNGDN  MLEPSPNMTW  FKGWKINRKD  GSASGTTLLE  ALDAIQPPTR  240
241   PTDKPLRLPL  QDVYKIGGIG  TVPVGRVETG  ILKPGMVVTF  APVNVTTEVK  SVEMHHEALT  300
301   EALPGDNVGF  NVKNVSVKDI  RRGNVAGDSK  NDPPQEAANF  TAQVIILNHP  GQISAGYAPV  360
361   LDCHTAHIAC  KFAELKEKID  RRSGKKLEDN  PKSLKSGDAA  IVDMIPGKPM  CVESFSEYPP  420
421   LGRFAVRDMR  QTVAVGVIKG  VEKKLSTTGK  ITKSAQKAQR  NK  462
Nucleotide CDS Sequence (FASTA)
1     ATGGGAAAGG  AGAAGCTCCA  CATCAACATA  GTCGTGATCG  GCCATGTGGA  CTCTGGCAAG  60
61    TCCACCACTA  CAGGACACCT  CATCTACAAG  TGTGGTGGCA  TCGACAAGAG  AACGATTGAG  120
121   AAGTTCGAGA  AAGAAGCTGC  TGAGATGGGG  AAGGGCTCAT  TCAAGTACGC  CTGGGTGCTC  180
181   GACAAGTTAA  AGGCAGAGAG  GGAGCGTGGC  ATTACAATAG  ACATCTCGCT  TTGGAAGTTT  240
241   GAGACCAGCA  AGTACTATGT  TACCATCATA  GATGCTCCAG  GCCACAGGGA  CTTCATCAAG  300
301   AACATGATCA  CTGGTACCTC  TCAGGCTGAC  TGTGCCGTGC  TCATTGTAGC  GGCAGGCGTA  360
361   GGAGAGTTCG  AGGCCGGCAT  CTCCAAGAAC  GGACAAACTC  GGGAGCACGC  TCTCCTGGCG  420
421   TACACGCTCG  GAGTGAAGCA  GCTGATTGTG  GGCATCAACA  AAATGGACTC  GACCGAGCCA  480
481   AACTACAGCC  AGAAGCGCTA  CGAGGAGATT  GTGAAGGAAG  TGAGCACCTA  CATCAAGAAG  540
541   ATTGGCTACA  ACCCAGACAC  TGTCGCCTTC  GTGCCCATCT  CTGGTTGGAA  TGGAGACAAC  600
601   ATGCTGGAGC  CAAGCCCAAA  CATGACATGG  TTTAAGGGGT  GGAAGATTAA  CAGGAAGGAT  660
661   GGCAGTGCAT  CAGGGACCAC  ACTGTTGGAG  GCTCTGGATG  CTATTCAGCC  CCCAACCCGC  720
721   CCAACAGACA  AACCTCTACG  TCTTCCCTTG  CAGGATGTCT  ACAAAATCGG  AGGTATTGGA  780
781   ACTGTGCCTG  TGGGTCGGGT  GGAAACAGGA  ATACTGAAAC  CCGGCATGGT  TGTGACGTTT  840
841   GCGCCTGTTA  ATGTGACCAC  CGAGGTGAAG  TCTGTGGAGA  TGCACCATGA  GGCACTGACG  900
901   GAGGCCCTCC  CAGGCGACAA  CGTGGGCTTC  AACGTCAAGA  ATGTGTCAGT  GAAGGACATT  960
961   CGCCGTGGCA  ACGTGGCTGG  GGATAGCAAG  AACGACCCTC  CACAGGAAGC  TGCCAACTTC  1020
1021  ACTGCTCAGG  TGATTATCCT  CAACCATCCT  GGGCAGATCA  GTGCTGGTTA  TGCTCCTGTG  1080
1081  CTGGACTGCC  ACACTGCTCA  TATCGCCTGC  AAGTTTGCAG  AGCTCAAGGA  AAAAATTGAC  1140
1141  CGGCGCTCTG  GCAAGAAGCT  GGAAGACAAT  CCCAAATCTC  TCAAATCTGG  AGATGCCGCC  1200
1201  ATCGTTGATA  TGATTCCTGG  CAAGCCTATG  TGTGTTGAGA  GCTTCTCCGA  GTATCCTCCG  1260
1261  TTGGGTCGTT  TTGCGGTGCG  TGACATGCGT  CAGACCGTGG  CAGTGGGAGT  GATAAAAGGT  1320
1321  GTGGAGAAGA  AATTGTCTAC  CACTGGTAAA  ATCACCAAGT  CTGCTCAGAA  GGCCCAGAGG  1380
1381  AACAAATGA  1389

▼ KEYWORD

ID
Family
Complete proteome
Elongation factor
GTP-binding
Nucleotide-binding
Protein biosynthesis
Reference proteome

▼ GENE ONTOLOGY

ID
Classification
Description
Molecular Function
GTP binding
Molecular Function
GTPase activity
Molecular Function
Translation elongation factor activity

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Pof-0455Poecilia formosa99.350.0 948
LLPS-Ten-1602Tetraodon nigroviridis98.480.0 942
LLPS-Orn-1000Oreochromis niloticus98.270.0 937
LLPS-Dar-2646Danio rerio97.620.0 936
LLPS-Icp-0960Ictalurus punctatus97.620.0 933
LLPS-Leo-1098Lepisosteus oculatus96.970.0 926
LLPS-Scm-0290Scophthalmus maximus96.720.0 857
LLPS-Asm-1471Astyanax mexicanus96.540.0 921
LLPS-Scf-3815Scleropages formosus96.320.0 924
LLPS-Gaa-2233Gasterosteus aculeatus95.670.0 915
LLPS-Fia-0680Ficedula albicollis95.110.0 882
LLPS-Gaga-0208Gallus gallus95.060.0 876
LLPS-Urm-0373Ursus maritimus94.790.0 834
LLPS-Tar-0687Takifugu rubripes94.620.0 899
LLPS-Man-0850Macaca nemestrina94.580.0 831
LLPS-Pap-1160Pan paniscus94.540.0 828
LLPS-Tag-0475Taeniopygia guttata94.370.0 901
LLPS-Anc-1473Anolis carolinensis94.370.0 903
LLPS-Ict-0438Ictidomys tridecemlineatus94.160.0 902
LLPS-Meg-2585Meleagris gallopavo94.160.0 900
LLPS-Anp-0246Anas platyrhynchos94.160.0 900
LLPS-Ran-2672Rattus norvegicus94.160.0 902
LLPS-Myl-0197Myotis lucifugus94.160.0 901
LLPS-Tut-1083Tursiops truncatus94.160.0 902
LLPS-Dio-0217Dipodomys ordii94.160.0 902
LLPS-Mea-0496Mesocricetus auratus94.160.0 902
LLPS-Mum-0218Mus musculus94.160.0 902
LLPS-Nol-0265Nomascus leucogenys93.940.0 900
LLPS-Eqc-1432Equus caballus93.940.0 900
LLPS-Cap-2850Cavia porcellus93.940.0 900
LLPS-Poa-3031Pongo abelii93.940.0 900
LLPS-Caf-1529Canis familiaris93.940.0 900
LLPS-Mam-0494Macaca mulatta93.940.0 900
LLPS-Rhb-0449Rhinopithecus bieti93.940.0 900
LLPS-Orc-2866Oryctolagus cuniculus93.940.0 900
LLPS-Fec-1683Felis catus93.940.0 900
LLPS-Pat-0141Pan troglodytes93.940.0 900
LLPS-Hos-2726Homo sapiens93.940.0 900
LLPS-Ova-2121Ovis aries93.940.0 900
LLPS-Bot-0075Bos taurus93.940.0 900
LLPS-Gog-1174Gorilla gorilla93.940.0 900
LLPS-Fud-3312Fukomys damarensis93.940.0 900
LLPS-Chs-0018Chlorocebus sabaeus93.940.0 900
LLPS-Maf-0027Macaca fascicularis93.940.0 900
LLPS-Cea-1677Cercocebus atys93.940.0 900
LLPS-Sah-0516Sarcophilus harrisii93.940.0 900
LLPS-Sus-1503Sus scrofa93.780.0 845
LLPS-Cas-3574Carlito syrichta93.720.0 900
LLPS-Mod-2181Monodelphis domestica93.720.0 899
LLPS-Aim-0646Ailuropoda melanoleuca93.610.0 881
LLPS-Xet-1247Xenopus tropicalis93.510.0 896
LLPS-Mal-2112Mandrillus leucophaeus92.40.0 821
LLPS-Ora-0021Ornithorhynchus anatinus91.960.0 883
LLPS-Mup-1483Mustela putorius furo91.920.0 820
LLPS-Pes-2103Pelodiscus sinensis91.890.0 836
LLPS-Loa-2715Loxodonta africana91.80.0 826
LLPS-Caj-0584Callithrix jacchus91.770.0 876
LLPS-Otg-2241Otolemur garnettii91.520.0 883
LLPS-Paa-0083Papio anubis91.520.0 883
LLPS-Aon-0720Aotus nancymaae91.520.0 883
LLPS-Orl-1101Oryzias latipes89.610.0 866
LLPS-Lac-3741Latimeria chalumnae89.570.0 862
LLPS-Drm-0656Drosophila melanogaster84.510.0 808
LLPS-Cii-1838Ciona intestinalis84.180.0 800
LLPS-Cis-1509Ciona savignyi83.840.0 791
LLPS-Miv-0526Microbotryum violaceum83.190.0 785
LLPS-Cae-1606Caenorhabditis elegans82.90.0 798
LLPS-Nec-1445Neurospora crassa82.780.0 787
LLPS-Coo-0161Colletotrichum orbiculare82.120.0 788
LLPS-Dos-1004Dothistroma septosporum81.720.0 758
LLPS-Cogr-0071Colletotrichum graminicola81.560.0 793
LLPS-Scs-0035Sclerotinia sclerotiorum81.460.0 770
LLPS-Trr-0140Trichoderma reesei81.240.0 776
LLPS-Kop-1070Komagataella pastoris81.240.0 771
LLPS-Beb-0492Beauveria bassiana81.130.0 790
LLPS-Scj-0167Schizosaccharomyces japonicus81.090.0 783
LLPS-Mel-0450Melampsora laricipopulina81.020.0 775
LLPS-Fuv-1338Fusarium verticillioides81.020.0 776
LLPS-Pytr-0366Pyrenophora triticirepentis80.870.0 779
LLPS-Sac-1187Saccharomyces cerevisiae80.810.0 758
LLPS-Trv-0177Trichoderma virens80.710.0 770
LLPS-Fus-0148Fusarium solani80.570.0 775
LLPS-Fuo-0468Fusarium oxysporum80.560.0 741
LLPS-Lem-1156Leptosphaeria maculans80.430.0 771
LLPS-Pyt-0448Pyrenophora teres80.350.0 770
LLPS-Scc-0584Schizosaccharomyces cryophilus80.350.0 779
LLPS-Zyt-0398Zymoseptoria tritici80.310.0 752
LLPS-Scp-0321Schizosaccharomyces pombe80.310.0 765
LLPS-Yal-0190Yarrowia lipolytica80.130.0 761
LLPS-Asg-0864Ashbya gossypii80.00.0 772
LLPS-Pug-0332Puccinia graminis79.870.0 765
LLPS-Phn-1410Phaeosphaeria nodorum79.830.0 765
LLPS-Asc-0786Aspergillus clavatus79.740.0 771
LLPS-Asfu-0115Aspergillus fumigatus79.690.0 767
LLPS-Usm-0916Ustilago maydis79.650.0 774
LLPS-Spr-1037Sporisorium reilianum79.520.0 775
LLPS-Asf-0318Aspergillus flavus79.520.0 768
LLPS-Cog-1446Colletotrichum gloeosporioides79.470.0 752
LLPS-Nef-1081Neosartorya fischeri79.390.0 776
LLPS-Blg-0925Blumeria graminis79.230.0 748
LLPS-Aso-0526Aspergillus oryzae78.820.0 764
LLPS-Orbr-1640Oryza brachyantha78.60.0 720
LLPS-Org-1512Oryza glaberrima78.380.0 719
LLPS-Ors-0930Oryza sativa78.380.0 719
LLPS-Brd-1791Brachypodium distachyon78.380.0 720
LLPS-Orni-1920Oryza nivara78.380.0 719
LLPS-Ori-0122Oryza indica78.380.0 719
LLPS-Orb-1453Oryza barthii78.380.0 719
LLPS-Ast-0634Aspergillus terreus78.340.0 754
LLPS-Ved-0320Verticillium dahliae78.330.0 754
LLPS-Crn-0041Cryptococcus neoformans78.320.0 748
LLPS-Asn-1218Aspergillus nidulans78.250.0 769
LLPS-Orp-0316Oryza punctata78.20.0 714
LLPS-Sob-1702Sorghum bicolor78.150.0 719
LLPS-Sei-0820Setaria italica78.150.0 719
LLPS-Prp-1348Prunus persica77.930.0 720
LLPS-Lep-2161Leersia perrieri77.930.0 717
LLPS-Glm-0124Glycine max77.930.0 720
LLPS-Amt-0656Amborella trichopoda77.780.0 733
LLPS-Vir-1095Vigna radiata77.780.0 737
LLPS-Via-1778Vigna angularis77.780.0 738
LLPS-Zem-1334Zea mays77.70.0 718
LLPS-Sem-0171Selaginella moellendorffii77.630.0 721
LLPS-Gor-1979Gossypium raimondii77.560.0 734
LLPS-Mae-0899Manihot esculenta77.460.0 731
LLPS-Cym-0514Cyanidioschyzon merolae77.430.0 724
LLPS-Php-2101Physcomitrella patens77.40.0 718
LLPS-Met-0003Medicago truncatula77.390.0 729
LLPS-Coc-0924Corchorus capsularis77.340.0 733
LLPS-Tra-2512Triticum aestivum77.340.0 727
LLPS-Hov-0895Hordeum vulgare77.340.0 729
LLPS-Tru-0952Triticum urartu77.240.0 724
LLPS-Pot-0495Populus trichocarpa77.240.0 729
LLPS-Thc-1793Theobroma cacao77.240.0 728
LLPS-Phv-1536Phaseolus vulgaris77.120.0 734
LLPS-Hea-1368Helianthus annuus76.960.0 711
LLPS-Viv-0600Vitis vinifera76.910.0 729
LLPS-Mao-0072Magnaporthe oryzae76.890.0 743
LLPS-Dac-0254Daucus carota76.590.0 723
LLPS-Sot-1266Solanum tuberosum76.370.0 723
LLPS-Sol-1712Solanum lycopersicum76.370.0 724
LLPS-Gas-0616Galdieria sulphuraria76.340.0 711
LLPS-Put-0261Puccinia triticina76.330.0 722
LLPS-Nia-1021Nicotiana attenuata76.250.0 726
LLPS-Bro-0690Brassica oleracea76.150.0 721
LLPS-Brr-0762Brassica rapa76.150.0 724
LLPS-Brn-1469Brassica napus76.150.0 722
LLPS-Map-0651Magnaporthe poae76.030.0 738
LLPS-Gag-1009Gaeumannomyces graminis76.010.0 745
LLPS-Art-1043Arabidopsis thaliana75.930.0 721