• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Xim-1579

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Isocitrate dehydrogenase [NAD] subunit, mitochondrial
Ensembl Gene: ENSXMAG00000010795.2
Ensembl Protein: ENSXMAP00000010824.2
Organism: Xiphophorus maculatus
Taxa ID: 8083
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Nucleolus, Postsynaptic densityPredicted from orthologs(View)

▼ SEQUENCE

Protein Sequence (FASTA)
1     MAAHSAVLSV  SRIINPIWGR  HLGNTVKVFG  TTLTSHRNKT  LHVSDNIPPP  AKYGGRHTVT  60
61    LIPGDGIGPE  LLSHVVEVFR  FSCVPVDFEV  VHVNSALEAE  DDIDNAITAI  RRNGVALKGN  120
121   IETKHTMPPS  MKSRNNLLRT  SLDLYANVMH  CQSLPGVQTR  HRNIDIMIIR  ENTEGEYSSL  180
181   EHESVSGVVE  CLKIITRSNS  LRIAEYAFQL  AREKGRRRVT  AVHKANIMKL  GDGLFLQCCR  240
241   EVASGYPDIT  FDSMIVDNTT  MQLVSKPQQF  DVMVMPNLYG  NVVSNVCAGL  VGGPGLVPGA  300
301   NYGRDYAVFE  TATRNTGKSV  AGKNIANPTA  MLLASCMMLD  HLKLYNYANL  IRNAVLTTMN  360
361   ETRLHTADLG  GQGTTSEVVQ  SIMRIIQSKG  QLTADI  396
Nucleotide CDS Sequence (FASTA)
1     ATGGCTGCTC  ACAGTGCTGT  GCTCTCTGTC  TCCAGGATTA  TAAATCCTAT  CTGGGGTCGA  60
61    CACTTGGGAA  ATACGGTTAA  AGTATTTGGA  ACAACTTTGA  CAAGTCACCG  GAATAAAACA  120
121   CTTCATGTTC  CCCCTCCTGC  AAAGTATGGA  GGTCGACACA  CTGTGACCCT  GATACCCGGG  180
181   GATGGAATCG  GTCCAGAGCT  TCTGAGTCAT  GTTGTAGAGG  TTTTCAGGTT  CAGCTGTGTG  240
241   CCTGTGGACT  TTGAGGTTGT  GCATGTCAAC  TCTGCACTGG  AGGCCGAGGA  CGATATCGAT  300
301   AATGCCATTA  CCGCCATCCG  CCGAAATGGA  GTTGCTCTTA  AAGGTAACAT  AGAGACCAAA  360
361   CATACCATGC  CGCCATCTAT  GAAATCCAGA  AATAATCTTC  TACGCACAAG  CTTGGATCTG  420
421   TATGCCAACG  TGATGCACTG  CCAGTCCCTC  CCTGGAGTCC  AAACTCGGCA  CAGGAACATC  480
481   GACATCATGA  TCATCAGGGA  GAACACAGAA  GGAGAATACA  GCAGTCTGGA  GCACGAGAGT  540
541   GTATCGGGTG  TAGTGGAGTG  TCTGAAGATC  ATCACCAGGA  GCAATTCCCT  CCGGATTGCT  600
601   GAGTATGCGT  TTCAACTGGC  TCGGGAGAAA  GGTCGTCGCA  GGGTCACTGC  AGTGCATAAA  660
661   GCCAATATCA  TGAAGCTTGG  AGACGGCTTG  TTTTTGCAGT  GCTGCAGGGA  AGTGGCCTCT  720
721   GGATACCCCG  ACATCACTTT  CGACAGCATG  ATCGTGGATA  ACACCACCAT  GCAGCTTGTG  780
781   TCCAAACCCC  AACAGTTTGA  CGTGATGGTG  ATGCCTAATC  TGTATGGGAA  CGTTGTCAGC  840
841   AACGTGTGCG  CCGGCCTGGT  GGGAGGGCCT  GGCCTTGTGC  CTGGCGCTAA  TTATGGTCGG  900
901   GACTATGCCG  TGTTTGAAAC  GGCTACAAGG  AACACAGGGA  AAAGTGTTGC  AGGGAAAAAC  960
961   ATTGCTAACC  CCACTGCTAT  GCTGCTGGCT  AGTTGCATGA  TGCTGGACCA  CCTCAAGCTT  1020
1021  TACAACTATG  CCAACTTGAT  AAGGAATGCA  GTACTCACCA  CAATGAATGA  AACCAGGTTG  1080
1081  CACACAGCAG  ATCTAGGAGG  TCAGGGCACC  ACATCTGAGG  TGGTCCAATC  CATCATGAGG  1140
1141  ATCATCCAGA  GCAAAGGACA  GCTCACTGCA  GACATCTAA  1179

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Pof-3784Poecilia formosa97.710.0 681
LLPS-Ten-3517Tetraodon nigroviridis92.550.0 650
LLPS-Gaa-2446Gasterosteus aculeatus92.070.0 650
LLPS-Tar-1399Takifugu rubripes91.960.0 616
LLPS-Scm-2320Scophthalmus maximus89.140.0 710
LLPS-Orl-1354Oryzias latipes88.380.0 704
LLPS-Orn-3267Oreochromis niloticus87.880.0 694
LLPS-Dar-3599Danio rerio84.280.0 657
LLPS-Scf-2980Scleropages formosus83.10.0 563
LLPS-Icp-4144Ictalurus punctatus81.650.0 607
LLPS-Urm-2230Ursus maritimus80.293e-151 439
LLPS-Anc-3064Anolis carolinensis79.470.0 544
LLPS-Ova-0863Ovis aries78.890.0 537
LLPS-Orc-2008Oryctolagus cuniculus78.70.0 532
LLPS-Aim-4040Ailuropoda melanoleuca78.590.0 535
LLPS-Caj-1240Callithrix jacchus78.590.0 537
LLPS-Xet-3381Xenopus tropicalis78.530.0 544
LLPS-Asm-2104Astyanax mexicanus78.480.0 597
LLPS-Sus-2034Sus scrofa78.30.0 535
LLPS-Fec-1905Felis catus78.30.0 533
LLPS-Paa-1220Papio anubis78.240.0 530
LLPS-Mam-3358Macaca mulatta78.240.0 530
LLPS-Man-4234Macaca nemestrina78.240.0 530
LLPS-Eqc-4310Equus caballus78.19e-165 475
LLPS-Tut-0836Tursiops truncatus78.010.0 530
LLPS-Ora-0689Ornithorhynchus anatinus78.010.0 530
LLPS-Cap-0072Cavia porcellus77.420.0 531
LLPS-Nol-3026Nomascus leucogenys77.350.0 521
LLPS-Fud-1968Fukomys damarensis77.010.0 532
LLPS-Ran-4491Rattus norvegicus76.790.0 536
LLPS-Mum-4551Mus musculus76.790.0 536
LLPS-Caf-2408Canis familiaris76.790.0 535
LLPS-Rhb-1714Rhinopithecus bieti76.570.0 537
LLPS-Dio-3376Dipodomys ordii76.50.0 534
LLPS-Otg-3380Otolemur garnettii76.50.0 535
LLPS-Mal-3018Mandrillus leucophaeus76.290.0 535
LLPS-Maf-3503Macaca fascicularis76.290.0 535
LLPS-Cea-3456Cercocebus atys76.290.0 535
LLPS-Poa-3225Pongo abelii76.290.0 535
LLPS-Mea-4553Mesocricetus auratus75.620.0 537
LLPS-Mup-4031Mustela putorius furo75.560.0 535
LLPS-Ict-2810Ictidomys tridecemlineatus75.420.0 527
LLPS-Loa-0678Loxodonta africana74.790.0 533
LLPS-Lac-2484Latimeria chalumnae74.740.0 567
LLPS-Myl-3488Myotis lucifugus74.240.0 534
LLPS-Mod-3384Monodelphis domestica73.30.0 545
LLPS-Bot-0993Bos taurus73.14e-167 481
LLPS-Aon-2446Aotus nancymaae73.10.0 525
LLPS-Chs-1384Chlorocebus sabaeus72.580.0 530
LLPS-Gog-3439Gorilla gorilla71.760.0 535
LLPS-Pap-3652Pan paniscus71.760.0 536
LLPS-Pat-2585Pan troglodytes71.760.0 536
LLPS-Sah-1596Sarcophilus harrisii71.730.0 533
LLPS-Hos-0802Homo sapiens71.50.0 535
LLPS-Cii-0426Ciona intestinalis61.293e-134 397
LLPS-Cae-0386Caenorhabditis elegans59.592e-134 397
LLPS-Cis-1528Ciona savignyi59.53e-136 402
LLPS-Abg-0586Absidia glauca56.517e-114 345
LLPS-Meg-1389Meleagris gallopavo56.416e-87 274
LLPS-Drm-2297Drosophila melanogaster54.251e-127 380
LLPS-Gas-1141Galdieria sulphuraria52.344e-111 338
LLPS-Ori-1652Oryza indica51.998e-89 278
LLPS-Met-1690Medicago truncatula51.659e-98 303
LLPS-Usm-1491Ustilago maydis51.614e-104 320
LLPS-Via-1303Vigna angularis51.512e-97 302
LLPS-Prp-2527Prunus persica51.353e-97 301
LLPS-Asg-0344Ashbya gossypii51.341e-105 323
LLPS-Spr-1218Sporisorium reilianum51.322e-103 318
LLPS-Php-1625Physcomitrella patens51.065e-105 322
LLPS-Mel-0474Melampsora laricipopulina51.035e-103 317
LLPS-Miv-0463Microbotryum violaceum51.015e-107 327
LLPS-Arl-2043Arabidopsis lyrata50.916e-103 317
LLPS-Orgl-2412Oryza glumaepatula50.887e-97 301
LLPS-Orni-1254Oryza nivara50.883e-97 301
LLPS-Thc-0254Theobroma cacao50.888e-98 303
LLPS-Dac-1671Daucus carota50.882e-98 305
LLPS-Orr-1227Oryza rufipogon50.887e-97 301
LLPS-Orm-0369Oryza meridionalis50.886e-97 301
LLPS-Org-0197Oryza glaberrima50.888e-97 301
LLPS-Ors-1670Oryza sativa50.886e-97 301
LLPS-Sob-2145Sorghum bicolor50.882e-97 302
LLPS-Scp-1119Schizosaccharomyces pombe50.731e-107 328
LLPS-Mua-2471Musa acuminata50.612e-103 318
LLPS-Coc-2134Corchorus capsularis50.613e-103 317
LLPS-Brr-2545Brassica rapa50.617e-102 313
LLPS-Chr-0435Chlamydomonas reinhardtii50.61e-99 306
LLPS-Cus-1235Cucumis sativus50.61e-102 316
LLPS-Lep-1427Leersia perrieri50.592e-97 302
LLPS-Phv-1823Phaseolus vulgaris50.592e-96 299
LLPS-Amt-0238Amborella trichopoda50.587e-97 301
LLPS-Fuo-0722Fusarium oxysporum50.572e-106 325
LLPS-Fus-0697Fusarium solani50.574e-106 325
LLPS-Sem-0514Selaginella moellendorffii50.312e-102 314
LLPS-Viv-2013Vitis vinifera50.315e-103 316
LLPS-Brn-1996Brassica napus50.31e-101 313
LLPS-Bro-1396Brassica oleracea50.31e-101 313
LLPS-Fuv-0608Fusarium verticillioides50.295e-106 324
LLPS-Vir-1861Vigna radiata50.152e-101 312
LLPS-Hea-1235Helianthus annuus50.151e-99 308
LLPS-Nec-0015Neurospora crassa50.141e-105 324
LLPS-Trv-0819Trichoderma virens50.149e-102 313
LLPS-Sac-1086Saccharomyces cerevisiae49.852e-102 315
LLPS-Mae-2396Manihot esculenta49.723e-98 304
LLPS-Gor-1088Gossypium raimondii49.694e-100 309
LLPS-Orbr-1000Oryza brachyantha49.692e-101 312
LLPS-Glm-1114Glycine max49.546e-101 311
LLPS-Kop-0738Komagataella pastoris49.423e-106 324
LLPS-Chc-1120Chondrus crispus49.413e-91 287
LLPS-Orb-1213Oryza barthii49.393e-101 312
LLPS-Orp-0391Oryza punctata49.392e-101 312
LLPS-Hov-1278Hordeum vulgare49.089e-100 308
LLPS-Zem-0396Zea mays49.085e-99 306
LLPS-Tru-1194Triticum urartu49.083e-100 309
LLPS-Art-2009Arabidopsis thaliana48.934e-96 299
LLPS-Map-1230Magnaporthe poae48.859e-102 314
LLPS-Brd-0345Brachypodium distachyon48.773e-99 306
LLPS-Sot-2027Solanum tuberosum48.599e-93 290
LLPS-Cym-0930Cyanidioschyzon merolae48.521e-102 317
LLPS-Nia-2445Nicotiana attenuata48.474e-98 303
LLPS-Sol-1990Solanum lycopersicum48.452e-93 291
LLPS-Scc-0945Schizosaccharomyces cryophilus48.413e-100 309
LLPS-Mao-1465Magnaporthe oryzae48.286e-103 317
LLPS-Sei-1760Setaria italica48.182e-98 305
LLPS-Tra-1989Triticum aestivum47.559e-97 300
LLPS-Crn-1109Cryptococcus neoformans47.455e-87 275
LLPS-Pot-2638Populus trichocarpa46.87e-102 313
LLPS-Cogr-1058Colletotrichum graminicola46.257e-87 275
LLPS-Tum-0786Tuber melanosporum46.23e-96 300
LLPS-Coo-1178Colletotrichum orbiculare45.657e-87 275
LLPS-Asc-1478Aspergillus clavatus45.45e-87 276
LLPS-Ast-1286Aspergillus terreus45.14e-89 281
LLPS-Zyt-1339Zymoseptoria tritici45.053e-86 274
LLPS-Tag-3368Taeniopygia guttata44.932e-86 273
LLPS-Dos-1244Dothistroma septosporum44.913e-87 276
LLPS-Leo-3746Lepisosteus oculatus43.941e-87 277
LLPS-Pytr-1014Pyrenophora triticirepentis43.793e-86 274