LLPS-Xet-a996
lpcat4
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | Lysophospholipid acyltransferase LPCAT4; 1-acylglycerol-3-phosphate O-acyltransferase 7; 1-AGP acyltransferase 7; 1-AGPAT 7; 1-acylglycerophosphocholine O-acyltransferase |
| Gene Name: | lpcat4, agpat7, aytl3, TEgg023j17.1 |
| Ensembl Gene: | ENSXETG00000016994.3 |
| Ensembl Protein: | ENSXETP00000059828.1 |
| Organism: | Xenopus tropicalis |
| Taxa ID: | 8364 |
| LLPS Type: | Client |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Postsynaptic density | Predicted from orthologs | (View) |
▼ FUNCTION
| Displays acyl-CoA-dependent lysophospholipid acyltransferase activity with a subset of lysophospholipids as substrates. Prefers long chain acyl-CoAs (C16, C18) as acyl donors (By similarity). |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSXETT00000063563.1 | ENSXETP00000059828.1 |
| Ensembl | ENSXETT00000037017.3 | ENSXETP00000037017.3 |
| UniProt | Q28C60, LPCT4_XENTR, Q5FWS1 | |
| GeneBank | BC089229, CR942439 | AAH89229.1, CAJ81339.1 |
| RefSeq | NM_001044398.1 | NP_001037863.1 |
| Entrez | 548367 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MSEAEPVGEK GPAEDDGEES VPFNPFLHEF EPEGFWQKAR FYILGFTLFP LRFLLAAIFL 60 61 FLMWPIAALR VAGLTEEELS RSIRHRRTIL HHLIYLLSRT MFFMCGFHWI TIRGRRAPAS 120 121 EAPLLVVAPH STFFDPIVTV VCDLPSVVSR VENLNIPVIG ALLRFNQSIL VSRQDPSSRK 180 181 KVVEEVKKRA TSNGDWPQVL FFPEGTNGNG KVLLKFKPGA FVAGVPVQPV LMRYPNKLPA 240 241 TIWTWKGNGV FKVLWLTMSQ FYINLEIEFL PVYHPTAEER ADPTLYASKV QKIMADALAK 300 301 PATEFELIGD TPVTPVGHLK VALDPKIWEL GNILEKAGFS LDSVQGLIDL CLEGVCSRVG 360 361 LDELAEKLGV TQHDVISRVF NYFHKDRVLV PFCENVLSRW SSDHSRSAFK GSNITSDLFS 420 421 TCDADGRFLL SADGFAAILR SVVGSPPAES GKVFSELCTY TELHGLTQDG FVRFAIRHPC 480 481 YRHLFLFYLR PPSSGRRKPP HIQQNGGCSG KNNPRNQSKM D 521 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGAGTGAGG CTGAGCCAGT AGGCGAGAAG GGCCCCGCTG AAGATGATGG CGAGGAGTCC 60 61 GTGCCGTTCA ACCCTTTCCT GCATGAGTTT GAGCCGGAAG GATTCTGGCA GAAGGCGAGG 120 121 TTCTATATCC TGGGTTTTAC CCTGTTCCCT CTGCGTTTCC TCCTGGCTGC TATCTTCCTC 180 181 TTCCTTATGT GGCCAATTGC TGCCCTTCGA GTGGCTGGAC TTACAGAAGA AGAGCTCAGT 240 241 CGCTCTATAC GGCACCGTCG CACCATTCTC CATCACCTGA TTTATCTCCT GAGTCGCACT 300 301 ATGTTCTTCA TGTGCGGCTT CCACTGGATC ACCATACGTG GCCGTCGCGC CCCTGCTTCT 360 361 GAGGCCCCAC TTCTGGTTGT AGCCCCTCAC TCCACCTTCT TTGATCCCAT AGTCACTGTG 420 421 GTGTGTGACC TTCCATCTGT TGTATCCCGA GTGGAGAATC TCAATATCCC AGTGATTGGA 480 481 GCACTGCTCC GTTTCAATCA GTCCATTTTG GTGTCCCGGC AAGATCCATC TTCACGGAAG 540 541 AAAGTAGTAG AGGAAGTGAA GAAACGCGCA ACCTCAAATG GAGATTGGCC TCAGGTGTTA 600 601 TTTTTTCCAG AGGGAACTAA TGGTAATGGC AAAGTTTTGC TAAAATTCAA ACCAGGTGCC 660 661 TTTGTTGCTG GGGTCCCAGT GCAGCCAGTG CTCATGAGGT ATCCCAACAA ATTGCCTGCA 720 721 ACTATCTGGA CATGGAAAGG GAATGGAGTG TTTAAGGTTC TGTGGCTCAC AATGTCTCAG 780 781 TTTTATATCA ACCTGGAAAT AGAGTTTCTG CCAGTTTATC ACCCTACTGC TGAGGAGCGG 840 841 GCTGATCCCA CACTCTATGC TTCCAAAGTG CAGAAGATAA TGGCTGATGC TCTGGCGAAA 900 901 CCAGCGACAG AGTTTGAGCT AATTGGAGAC ACACCAGTAA CACCAGTCGG GCACCTGAAA 960 961 GTGGCGCTGG ATCCCAAAAT TTGGGAACTT GGGAACATAT TAGAAAAGGC AGGGTTCTCT 1020 1021 CTTGATAGTG TGCAGGGTCT GATTGATCTT TGCCTAGAGG GGGTGTGCTC TCGCGTGGGA 1080 1081 TTAGATGAGC TTGCAGAAAA ACTGGGTGTG ACGCAGCACG ATGTGATCTC CAGAGTTTTC 1140 1141 AATTATTTCC ACAAGGACAG AGTATTAGTG CCCTTTTGTG AAAATGTTTT AAGTAGATGG 1200 1201 TCTAGCGATC ACAGTAGGTC TGCCTTTAAA GGTTGTTCCC TAAAATTCGA TCTCTTTTCT 1260 1261 ACCTGTGATG CTGATGGCCG TTTTCTTCTC TCTGCTGATG GATTTGCAGC CATATTGCGT 1320 1321 TCGGTTGTGG GCTCACCCCC TGCTGAAAGT GGTAAAGTGT TCTCAGAGTT GTGCACTTAC 1380 1381 ACGGAGCTGC ATGGCCTGAC TCAGGATGGA TTTGTGCGTT TTGCCATTCG ACATCCTTGT 1440 1441 TATCGTCACC TGTTTCTTTT CTACCTGCGC CCCCCGTCTT CTGGTCGCCG AAAGCCACCT 1500 1501 CATATCCAGC AAAATGGGGG TTGTTCTGGG AAAAACAACC CTCGGAACCA ATCCAAAATG 1560 1561 GATTGA 1566 |
▼ KEYWORD
ID | Family |
Acyltransferase | |
Complete proteome | |
Endoplasmic reticulum | |
Glycoprotein | |
Lipid biosynthesis | |
Lipid metabolism | |
Membrane | |
Phospholipid biosynthesis | |
Phospholipid metabolism | |
Reference proteome | |
Transferase | |
Transmembrane | |
Transmembrane helix
|
▼ GENE ONTOLOGY
ID | Classification | Description |
Cellular Component | Endoplasmic reticulum membrane | |
Cellular Component | Integral component of membrane | |
Molecular Function | 1-acylglycerophosphocholine O-acyltransferase activity | |
Molecular Function | 1-alkenylglycerophosphoethanolamine O-acyltransferase activity | |
Molecular Function | 1-alkylglycerophosphocholine O-acetyltransferase activity | |
Biological Process | Phospholipid biosynthetic process |