LLPS-Xet-0722
npat
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | Nuclear protein, ataxia-telangiectasia locus |
| Gene Name: | npat |
| Ensembl Gene: | ENSXETG00000014476.3 |
| Ensembl Protein: | ENSXETP00000031680.2 |
| Organism: | Xenopus tropicalis |
| Taxa ID: | 8364 |
| LLPS Type: | LLPS regulator |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Cajal body, Histone locus body | Predicted from orthologs | (View) |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSXETT00000031680.2 | ENSXETP00000031680.2 |
| UniProt | F6U8E8, F6U8E8_XENTR | |
| GeneBank | AAMC01039072, AAMC01039074, AAMC01039073 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MLLPSDVARL VLGYLQQEKL SSTCQSFILE SPNLKEYAEH YTDEGSIPGC VLSLFGKNLT 60 61 TILNEYIALK AKENKEEIPV MVSALWKKLD HTLSQIRSMQ NCLLLPTNQK VRTRYGIQDL 120 121 RHQRMLTSHA ASTGSAMACQ QTSTPIAAKQ VMLRSFVSQS ASPTIVSPLV IGQSTIQCTN 180 181 SPATESKGET LQNSALSAAE KKQTSSPMRR KADCQRRRRF LNKYHATAIS YDQTTKRLVA 240 241 MQLVIENARE KILSNKSLQE KLAENINKFL GSDAAAHAAK PSEGGALEQD TSIDEILGLQ 300 301 GGEIHMSEEA IHDILEQTEL DPDFQELYDL FACIGSTKTT KTASRDPPLQ TEGVASSNTL 360 361 VANDNLEPME SSFEGGGKLL CILYYYLWKL IDTTSHSSNP TGVGAEQKKD PTPILTTQST 420 421 ESTGLPSKAQ GIPTSGSDRS AMSDQSVESK KRTDSIIILD STGSDTVVES SEDVQVTPME 480 481 IAVSQSQDVE MKNISHRDVV ETNCQLAKEA APLSVDLTVH GVQNSKKETP KERAPEKTSK 540 541 AKKSTPLKNE ISDSRQVERD KSEGPAEEHT AQSQNIVVLV SIGSPVTESN LLNDKNQQGE 600 601 VNATPSKIDT PIDSTVSEPL QAESSIASKE LKVPQKPSKA DKTPPHPVVP SVSPAIKGAS 660 661 SSSDGSSLPL QVSSSVAVPA PVSSNVEQSC IGMSSIDPSQ IITLSFITED IPEDAELTKA 720 721 VKSISERGNS ALLLSPFQKL QESSSIVSNP GPSTETSGLA LLDQREVVTV SSDVAAGVKP 780 781 AEECTIFSLP GTSNLSTDGG IIQLMPATSS SFAPSGSFFI STCNTGGAQQ SNIMVVPSNC 840 841 APAASQKQPC HYQTPPRPHS VYTVGQAISP KISQGSTFIL ASAMQPVLPG VVGMFPLSVV 900 901 GQSSNAFAAP SHQVLHVPVS QGVPKLPLPP KSQKLPSTRN LASAEKQGVA STTDSVSRTS 960 961 SSRGQRSENV DKNSAAVSQN KPEERQTGST NPSTKAAENH KRVLCFENSA ANRGTANTKS 1020 1021 VNNSSAPQNK DMVETVNSSG ASSALLPSKQ SGKDSKPDKK APSTETNSKS ESVPSKQPVV 1080 1081 PAPKDLSGDK KTVAVALSAE VHGGVMANKE NMLQKENKKQ ELPESNKKPA SSDGAAGNSE 1140 1141 RAAQPTHETG RKLASLPSIL RRTKLSTERM CPTSPLTKQA SDLLQSMQFN SPNAKHFSGG 1200 1201 DLPIPRTPGS GIDDRLVDNH PDHMKTPKSK RYHEDGGTPK PMLPPATPEL PACSPASETG 1260 1261 SENSVNMAAH TLMILSRATL AKTDSSSPLK DNTQQLKLSK SSSKKRKLDE PDEYERRPHK 1320 1321 KELQSPSAIL KRKKIKKHRK KSTDAFPAGM DVDKFLMSLH YDE 1363 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGCTTCTAC CGTCTGATGT GGCCCGGCTG GTGCTGGGCT ATCTGCAGCA AGAGAAACTC 60 61 TCTTCTACAT GCCAATCATT TATATTAGAG AGCCCCAACC TAAAGGAATA TGCAGAACAT 120 121 TATACTGATG AAGGGTCTAT TCCAGGCTGC GTATTGTCTC TGTTTGGGAA AAACCTGACA 180 181 ACGATTTTAA ATGAATATAT TGCCTTGAAA GCAAAAGAGA ATAAAGAAGA GATACCAGTC 240 241 ATGGTTTCAG CTCTGTGGAA GAAGCTTGAC CACACTCTCT CTCAGATAAG GAGTATGCAG 300 301 AACTGCCTGT TATTGCCCAC CAATCAAAAA GTCCGCACAA GATATGGAAT ACAGGACCTG 360 361 AGACACCAAA GAATGTTGAC ATCACATGCA GCTTCGACAG GGTCAGCCAT GGCATGCCAG 420 421 CAAACATCTA CTCCAATAGC AGCAAAGCAA GTCATGTTGA GGTCATTTGT GTCTCAAAGT 480 481 GCATCACCAA CCATTGTCAG CCCTTTGGTC ATTGGTCAGT CTACTATTCA GTGTACCAAC 540 541 TCTCCTGCTA CCGAAAGCAA AGGAGAGACA TTACAGAATT CTGCTTTGTC AGCTGCAGAG 600 601 AAGAAACAGA CTTCCTCACC TATGAGGCGA AAAGCGGATT GTCAAAGGAG AAGACGATTT 660 661 CTGAATAAAT ATCATGCCAC GGCAATTAGT TATGATCAGA CTACTAAAAG ATTGGTTGCT 720 721 ATGCAACTGG TAATAGAAAA TGCCAGAGAG AAGATTTTAA GTAACAAATC CCTGCAAGAG 780 781 AAGCTGGCGG AAAATATAAA CAAGTTTCTT GGAAGCGACG CAGCTGCCCA TGCAGCCAAG 840 841 CCATCCGAGG GAGGTGCTCT TGAACAGGAT ACTTCCATTG ATGAAATCCT TGGACTTCAG 900 901 GGAGGGGAGA TTCATATGTC AGAGGAAGCT ATTCATGATA TTCTAGAGCA AACTGAACTG 960 961 GATCCAGATT TCCAGGAGTT ATATGACCTT TTTGCTTGCA TAGGTTCGAC AAAGACAACA 1020 1021 AAAACTGCAT CTCGTGACCC TCCCTTACAA ACAGAAGGGG TTGCTTCCAG CAATACTCTA 1080 1081 GTGGCTAATG ATAACCTGGA ACCCATGGAA AGCTCTTTTG AAGGAGGTGG TAAGTTATTG 1140 1141 TGTATTTTAT ATTATTATTT ATGGAAACTA ATAGATACTA CATCACACTC CAGCAACCCC 1200 1201 ACAGGGGTGG GTGCAGAACA GAAGAAAGAC CCAACACCCA TCCTCACAAC ACAAAGTACT 1260 1261 GAAAGCACCG GACTTCCATC TAAAGCACAG GGAATACCAA CATCTGGCAG TGACAGATCC 1320 1321 GCCATGTCAG ATCAGAGTGT AGAGTCAAAG AAAAGAACTG ATTCCATCAT CATTCTGGAC 1380 1381 AGTACTGGAA GCGACACAGT AGTAGAATCC AGTGAGGACG TACAAGTAAC ACCTATGGAG 1440 1441 ATAGCAGTGT CACAGTCACA AGATGTTGAG ATGAAGAACA TTTCACATAG AGATGTGGTA 1500 1501 GAAACCAACT GTCAGTTGGC CAAAGAAGCA GCTCCATTGA GTGTTGACTT AACAGTTCAC 1560 1561 GGTGTTCAGA ATTCAAAGAA AGAGACTCCT AAAGAGAGAG CGCCTGAAAA GACAAGTAAA 1620 1621 GCTAAAAAAT CAACACCCTT AAAAAATGAG ATTTCAGACA GTCGGCAGGT GGAGAGGGAT 1680 1681 AAAAGTGAAG GCCCTGCGGA AGAACACACA GCACAGTCTC AGAATATTGT TGTACTGGTT 1740 1741 TCTATTGGAA GCCCTGTTAC AGAGTCAAAT CTTCTGAATG ATAAGAACCA ACAAGGGGAA 1800 1801 GTAAATGCAA CACCTAGCAA AATAGACACT CCTATTGATA GTACAGTGAG TGAACCTTTG 1860 1861 CAGGCAGAAA GCTCTATCGC ATCAAAGGAA CTAAAAGTGC CCCAGAAACC ATCAAAGGCA 1920 1921 GACAAGACAC CACCTCATCC GGTGGTGCCG TCTGTAAGTC CAGCCATAAA GGGAGCATCA 1980 1981 TCCAGTTCTG ATGGAAGCAG TCTTCCTTTA CAAGTCTCAA GCTCTGTGGC GGTACCAGCA 2040 2041 CCAGTCAGCA GCAATGTAGA GCAGTCCTGT ATTGGCATGT CCTCCATCGA TCCATCCCAA 2100 2101 ATAATAACTC TCAGCTTTAT CACTGAGGAT ATCCCAGAGG ATGCCGAGCT AACAAAGGCA 2160 2161 GTTAAAAGTA TCAGTGAAAG GGGCAACTCT GCTTTACTCT TGTCTCCTTT CCAAAAACTC 2220 2221 CAGGAAAGCA GTAGCATTGT TTCTAACCCA GGCCCCTCCA CCGAGACGTC GGGTTTGGCC 2280 2281 CTATTAGATC AGAGAGAAGT AGTGACTGTG TCCAGCGATG TTGCTGCTGG AGTGAAGCCA 2340 2341 GCTGAAGAAT GTACCATCTT CTCTCTGCCT GGGACTTCTA ATCTCTCCAC TGACGGGGGG 2400 2401 ATCATACAGC TAATGCCGGC CACAAGCTCT AGCTTTGCAC CATCAGGCAG CTTTTTTATC 2460 2461 AGCACGTGTA ACACTGGTGG CGCACAGCAG TCCAACATCA TGGTGGTACC CAGTAATTGT 2520 2521 GCTCCTGCTG CCAGCCAAAA GCAGCCATGC CATTATCAAA CCCCTCCCAG GCCACACAGT 2580 2581 GTGTATACAG TCGGACAGGC CATTTCACCT AAAATTTCAC AAGGTTCTAC CTTTATCCTG 2640 2641 GCCTCCGCTA TGCAGCCGGT GCTACCTGGT GTGGTGGGCA TGTTCCCTCT TTCTGTTGTT 2700 2701 GGGCAGAGCA GTAATGCGTT TGCAGCACCT TCTCACCAGG TTTTGCATGT ACCAGTTTCA 2760 2761 CAAGGCGTTC CCAAGCTGCC GCTCCCTCCG AAGTCTCAGA AACTTCCATC CACAAGAAAT 2820 2821 CTGGCAAGCG CAGAGAAGCA GGGAGTAGCC TCAACCACAG ATTCTGTGAG CCGAACATCG 2880 2881 AGCTCTCGAG GGCAGAGGTC AGAGAATGTT GATAAAAACT CTGCTGCCGT GTCACAGAAC 2940 2941 AAGCCGGAAG AGAGACAGAC AGGCAGCACC AATCCAAGCA CTAAAGCAGC TGAGAATCAT 3000 3001 AAGAGAGTGC TGTGCTTTGA GAATTCTGCT GCCAACAGGG GTACAGCAAA TACCAAGTCG 3060 3061 GTTAATAATA GCTCAGCACC CCAAAATAAA GATATGGTGG AGACCGTGAA CTCTTCTGGA 3120 3121 GCTTCCAGTG CTTTATTGCC TTCCAAGCAG AGTGGCAAAG ACAGCAAACC CGACAAAAAA 3180 3181 GCCCCAAGCA CAGAGACAAA CTCCAAGTCT GAGAGCGTTC CGTCCAAGCA GCCGGTTGTA 3240 3241 CCCGCTCCAA AGGATCTGTC GGGAGACAAG AAAACTGTGG CCGTAGCGTT GTCTGCAGAA 3300 3301 GTCCATGGTG GGGTCATGGC CAACAAGGAG AATATGTTAC AGAAGGAGAA TAAAAAGCAA 3360 3361 GAGCTACCAG AGTCCAACAA GAAACCTGCC AGTAGTGATG GTGCAGCTGG AAATTCCGAG 3420 3421 CGAGCCGCGC AACCAACCCA TGAAACTGGC AGGAAGCTTG CATCTCTGCC GAGCATACTA 3480 3481 AGGAGAACCA AATTATCCAC GGAAAGAATG TGCCCCACAA GTCCACTAAC TAAACAGGCC 3540 3541 AGTGACCTAT TGCAAAGCAT GCAGTTTAAC AGTCCCAATG CAAAACACTT CAGTGGGGGG 3600 3601 GACTTGCCAA TACCACGTAC CCCAGGCTCA GGAATTGATG ACAGATTGGT AGATAACCAC 3660 3661 CCAGACCATA TGAAAACCCC CAAATCTAAA CGCTACCATG AGGATGGAGG TACTCCCAAG 3720 3721 CCCATGCTGC CCCCTGCAAC CCCTGAGTTA CCAGCTTGTA GTCCGGCCAG TGAAACTGGC 3780 3781 AGTGAGAACA GTGTCAACAT GGCTGCCCAC ACGCTAATGA TACTGTCACG TGCCACCCTT 3840 3841 GCAAAGACTG ACAGCAGCTC TCCCCTAAAG GACAATACTC AGCAATTAAA ATTGTCCAAA 3900 3901 AGCTCTTCAA AGAAGAGAAA GCTCGATGAG CCTGATGAAT ATGAGAGGCG GCCGCATAAA 3960 3961 AAGGAGTTGC AGAGCCCCTC TGCCATTCTG AAAAGAAAGA AAATAAAGAA ACATCGGAAG 4020 4021 AAATCCACGG ATGCTTTCCC AGCTGGGATG GATGTGGACA AGTTCCTAAT GTCTCTGCAT 4080 4081 TATGATGAAT AA 4092 |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Ora-2141 | Ornithorhynchus anatinus | 75.0 | 2e-50 | 181 |
| LLPS-Xim-0078 | Xiphophorus maculatus | 61.24 | 8e-46 | 171 |
| LLPS-Ran-1956 | Rattus norvegicus | 55.14 | 6e-94 | 337 |
| LLPS-Bot-4642 | Bos taurus | 54.52 | 2e-94 | 338 |
| LLPS-Aon-2601 | Aotus nancymaae | 54.13 | 4e-92 | 331 |
| LLPS-Mup-2469 | Mustela putorius furo | 53.83 | 5e-94 | 337 |
| LLPS-Gog-1681 | Gorilla gorilla | 53.8 | 3e-91 | 328 |
| LLPS-Otg-0276 | Otolemur garnettii | 53.41 | 1e-91 | 330 |
| LLPS-Urm-1129 | Ursus maritimus | 53.37 | 2e-93 | 335 |
| LLPS-Ova-0006 | Ovis aries | 53.06 | 2e-88 | 320 |
| LLPS-Mod-0561 | Monodelphis domestica | 52.66 | 1e-94 | 338 |
| LLPS-Ict-3253 | Ictidomys tridecemlineatus | 52.34 | 2e-97 | 348 |
| LLPS-Orc-2334 | Oryctolagus cuniculus | 52.3 | 2e-85 | 310 |
| LLPS-Loa-0508 | Loxodonta africana | 52.14 | 8e-90 | 320 |
| LLPS-Aim-2383 | Ailuropoda melanoleuca | 52.12 | 5e-88 | 318 |
| LLPS-Myl-3550 | Myotis lucifugus | 51.69 | 4e-89 | 322 |
| LLPS-Sah-1852 | Sarcophilus harrisii | 51.26 | 4e-94 | 337 |
| LLPS-Fud-1899 | Fukomys damarensis | 51.03 | 4e-94 | 337 |
| LLPS-Tut-0057 | Tursiops truncatus | 50.89 | 1e-93 | 335 |
| LLPS-Fec-3415 | Felis catus | 50.87 | 2e-95 | 342 |
| LLPS-Mum-1615 | Mus musculus | 50.25 | 4e-93 | 334 |
| LLPS-Pap-0229 | Pan paniscus | 50.25 | 2e-92 | 332 |
| LLPS-Pat-2148 | Pan troglodytes | 50.25 | 2e-92 | 332 |
| LLPS-Eqc-2958 | Equus caballus | 50.12 | 1e-94 | 339 |
| LLPS-Cas-2208 | Carlito syrichta | 50.12 | 7e-93 | 333 |
| LLPS-Hos-0164 | Homo sapiens | 50.0 | 9e-92 | 330 |
| LLPS-Fia-1259 | Ficedula albicollis | 50.0 | 2e-96 | 344 |
| LLPS-Dio-0382 | Dipodomys ordii | 49.87 | 5e-86 | 312 |
| LLPS-Anp-1094 | Anas platyrhynchos | 49.61 | 7e-89 | 321 |
| LLPS-Chs-1556 | Chlorocebus sabaeus | 49.37 | 3e-92 | 331 |
| LLPS-Cea-0325 | Cercocebus atys | 49.37 | 5e-92 | 330 |
| LLPS-Asm-1698 | Astyanax mexicanus | 49.3 | 1e-82 | 301 |
| LLPS-Caj-3956 | Callithrix jacchus | 49.16 | 6e-93 | 333 |
| LLPS-Maf-1493 | Macaca fascicularis | 49.12 | 1e-91 | 329 |
| LLPS-Mam-1431 | Macaca mulatta | 49.12 | 1e-91 | 329 |
| LLPS-Tag-0506 | Taeniopygia guttata | 49.09 | 1e-86 | 314 |
| LLPS-Pof-3048 | Poecilia formosa | 48.86 | 6e-81 | 296 |
| LLPS-Mea-3842 | Mesocricetus auratus | 48.79 | 3e-94 | 337 |
| LLPS-Scf-2525 | Scleropages formosus | 48.73 | 8e-82 | 300 |
| LLPS-Anc-0110 | Anolis carolinensis | 48.49 | 1e-90 | 327 |
| LLPS-Dar-0994 | Danio rerio | 48.48 | 4e-79 | 290 |
| LLPS-Icp-2560 | Ictalurus punctatus | 48.07 | 2e-82 | 301 |
| LLPS-Paa-1973 | Papio anubis | 47.68 | 6e-85 | 309 |
| LLPS-Rhb-2734 | Rhinopithecus bieti | 47.62 | 3e-84 | 307 |
| LLPS-Tar-2878 | Takifugu rubripes | 47.43 | 7e-72 | 267 |
| LLPS-Caf-0632 | Canis familiaris | 47.33 | 1e-86 | 314 |
| LLPS-Ten-1802 | Tetraodon nigroviridis | 47.28 | 6e-80 | 272 |
| LLPS-Scm-1752 | Scophthalmus maximus | 47.18 | 1e-77 | 286 |
| LLPS-Orl-2506 | Oryzias latipes | 47.01 | 6e-78 | 287 |
| LLPS-Lac-1380 | Latimeria chalumnae | 46.78 | 7e-89 | 321 |
| LLPS-Poa-0872 | Pongo abelii | 46.52 | 2e-74 | 277 |
| LLPS-Man-1898 | Macaca nemestrina | 46.46 | 6e-82 | 300 |
| LLPS-Orn-3237 | Oreochromis niloticus | 46.46 | 2e-75 | 280 |
| LLPS-Gaa-1881 | Gasterosteus aculeatus | 45.28 | 5e-78 | 268 |
| LLPS-Leo-2752 | Lepisosteus oculatus | 43.9 | 2e-74 | 260 |
| LLPS-Sus-2289 | Sus scrofa | 43.3 | 2e-54 | 213 |
| LLPS-Mal-3028 | Mandrillus leucophaeus | 43.04 | 3e-64 | 244 |
| LLPS-Pes-1195 | Pelodiscus sinensis | 41.79 | 1e-105 | 372 |
| LLPS-Nol-0431 | Nomascus leucogenys | 39.69 | 4e-90 | 325 |
| LLPS-Cap-1487 | Cavia porcellus | 39.24 | 1e-87 | 317 |
| LLPS-Cii-2076 | Ciona intestinalis | 39.13 | 1e-11 | 70.5 |
| LLPS-Cis-0476 | Ciona savignyi | 33.59 | 1e-08 | 60.5 |