DrLLPS - Data resource of LLPS

LLPS-Viv-1178
VIT_15s0048g00930

Integrated Annotations

▼ OVERVIEW


Status:	Unreviewed
Protein Name:	ATP-dependent DNA helicase 2 subunit KU80
Gene Name:	VIT_15s0048g00930
Ensembl Gene:	VIT_15s0048g00930
Ensembl Protein:	VIT_15s0048g00930.t01
Organism:	Vitis vinifera
Taxa ID:	29760
LLPS Type:	Others

▼ PROPERTY

——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:

Condensate	Evidence	Orthologs
Chromatin, Nucleolus, Centrosome/Spindle pole body, P-body, Stress granule	Predicted from orthologs	(View)

Organism	DrLLPS ID	UniProt ID	LLPS type	Condensate	Identity	E-value	Score
Homo sapiens	LLPS-Hos-2089	P13010	Client	Nucleolus, P-body, Stress granule	24.82	5e-49	187
Mus musculus	LLPS-Mum-1325	P27641	Client	Chromatin, Nucleolus, Centrosome/Spindle pole body	23.10	4e-45	175

▼ FUNCTION

Single-stranded DNA-dependent ATP-dependent helicase.

▼ CROSS REFERENCE

Database	Nucleotide ID	Protein ID
Ensembl	VIT_15s0048g00930.t01	VIT_15s0048g00930.t01
UniProt		D7U7S3, D7U7S3_VITVI
GeneBank	FN596739	CBI38852.3

▼ SEQUENCE

Protein Sequence (FASTA)
1 MHTFLPEVEK LCSMLLQKKL IYSKNDEVGI VLFGTEDTNN ELTKEVGGYE HVVVLRHIKV 60 61 VDGDLVEALQ QLPRGTVAGD FLDAIVVGMD MLIKKFGSTN KGKKRLCLIT SALCPIKDPY 120 121 EGTKEDQIGT IAEQMSAHGM KLECIVARGR LSGNVDMRIM DENDLLLKLF STKTTAKTLY 180 181 VETPTSLLGA LRTRSIAPVT IFRGDLELSP KMRIKVWVYK KTAEERFPTL KQYSDQAPPT 240 241 DKFATHEVKV DFEYKSVEES SKVVPPEQRI KGYRYGPQVI PISSAEWEAV KFKPEKGVKL 300 301 LGFTDASNVM RHYYMHDVNI FIAEPSNTKA MLAVSALARA MKEMNKVAIL RCVWRQGQGS 360 361 VVIGILTPNV SDKDDIPDSF YFNVLPYAED VREFQFPSFS NLPASWQPNE EQQEAADNLV 420 421 KMLDLAPSGS KETLLPDLTP NPVLERFYRH LELKSKHPDA AVPPLDESLK KITEPDPKLL 480 481 SQNKPIIDAF RRRFELKENP KLKKSTRRLL RERPSGLNEE ASMGDGSDGQ AIKSIENTST 540 541 VGVEKIGDST PIQDFEAMMS CRDSPEWVGK AINEMKNKIF DLVEDSYEGD NYLKALEYLV 600 601 ALRKGCVLEQ EPKQFNDFLH HLYKYCEKHN LNSFCESLAS KEIMLINKTE AADSEVTEDE 660 661 ARSLMVKKEP KLE 673

Protein Sequence (FASTA)

1     MHTFLPEVEK  LCSMLLQKKL  IYSKNDEVGI  VLFGTEDTNN  ELTKEVGGYE  HVVVLRHIKV  60
61    VDGDLVEALQ  QLPRGTVAGD  FLDAIVVGMD  MLIKKFGSTN  KGKKRLCLIT  SALCPIKDPY  120
121   EGTKEDQIGT  IAEQMSAHGM  KLECIVARGR  LSGNVDMRIM  DENDLLLKLF  STKTTAKTLY  180
181   VETPTSLLGA  LRTRSIAPVT  IFRGDLELSP  KMRIKVWVYK  KTAEERFPTL  KQYSDQAPPT  240
241   DKFATHEVKV  DFEYKSVEES  SKVVPPEQRI  KGYRYGPQVI  PISSAEWEAV  KFKPEKGVKL  300
301   LGFTDASNVM  RHYYMHDVNI  FIAEPSNTKA  MLAVSALARA  MKEMNKVAIL  RCVWRQGQGS  360
361   VVIGILTPNV  SDKDDIPDSF  YFNVLPYAED  VREFQFPSFS  NLPASWQPNE  EQQEAADNLV  420
421   KMLDLAPSGS  KETLLPDLTP  NPVLERFYRH  LELKSKHPDA  AVPPLDESLK  KITEPDPKLL  480
481   SQNKPIIDAF  RRRFELKENP  KLKKSTRRLL  RERPSGLNEE  ASMGDGSDGQ  AIKSIENTST  540
541   VGVEKIGDST  PIQDFEAMMS  CRDSPEWVGK  AINEMKNKIF  DLVEDSYEGD  NYLKALEYLV  600
601   ALRKGCVLEQ  EPKQFNDFLH  HLYKYCEKHN  LNSFCESLAS  KEIMLINKTE  AADSEVTEDE  660
661   ARSLMVKKEP  KLE  673

▼ KEYWORD

ID	Family
KW-0067	ATP-binding
KW-0181	Complete proteome
KW-0227	DNA damage
KW-0233	DNA recombination
KW-0234	DNA repair
KW-0238	DNA-binding
KW-0347	Helicase
KW-0378	Hydrolase
KW-0547	Nucleotide-binding
KW-0539	Nucleus
KW-1185	Reference proteome

▼ GENE ONTOLOGY

ID	Classification	Description
GO:0043564	Cellular Component	Ku70:Ku80 complex
GO:0000784	Cellular Component	Nuclear chromosome, telomeric region
GO:0005524	Molecular Function	ATP binding
GO:0004003	Molecular Function	ATP-dependent DNA helicase activity
GO:0003684	Molecular Function	Damaged DNA binding
GO:0042162	Molecular Function	Telomeric DNA binding
GO:0071480	Biological Process	Cellular response to gamma radiation
GO:0071481	Biological Process	Cellular response to X-ray
GO:0006310	Biological Process	DNA recombination
GO:0006303	Biological Process	Double-strand break repair via nonhomologous end joining
GO:0000723	Biological Process	Telomere maintenance

▼ ORTHOLOGY

DrLLPS ID	Organism	Identity	E-value	Score
LLPS-Prp-1232	Prunus persica	75.33	0.0	1069
LLPS-Mae-0261	Manihot esculenta	73.7	0.0	1045
LLPS-Nia-0426	Nicotiana attenuata	72.43	0.0	1032
LLPS-Pot-1531	Populus trichocarpa	72.21	0.0	1050
LLPS-Dac-1531	Daucus carota	71.28	0.0	1014
LLPS-Cus-1741	Cucumis sativus	71.03	0.0	1016
LLPS-Met-1609	Medicago truncatula	71.03	0.0	981
LLPS-Hea-1863	Helianthus annuus	70.94	0.0	987
LLPS-Sot-1185	Solanum tuberosum	70.9	0.0	1007
LLPS-Thc-0503	Theobroma cacao	70.79	0.0	1027
LLPS-Glm-0604	Glycine max	70.62	0.0	981
LLPS-Amt-0432	Amborella trichopoda	70.11	0.0	671
LLPS-Phv-0802	Phaseolus vulgaris	69.64	0.0	969
LLPS-Via-0486	Vigna angularis	68.43	0.0	946
LLPS-Gor-1243	Gossypium raimondii	67.26	0.0	955
LLPS-Ors-1323	Oryza sativa	67.0	0.0	692
LLPS-Sol-0319	Solanum lycopersicum	65.85	0.0	967
LLPS-Mua-0547	Musa acuminata	65.22	0.0	602
LLPS-Vir-1005	Vigna radiata	64.08	0.0	919
LLPS-Art-0595	Arabidopsis thaliana	62.91	0.0	892
LLPS-Arl-0476	Arabidopsis lyrata	62.91	0.0	894
LLPS-Bro-2271	Brassica oleracea	62.7	0.0	879
LLPS-Brn-1034	Brassica napus	62.67	0.0	879
LLPS-Brr-0199	Brassica rapa	62.56	0.0	881
LLPS-Brd-1332	Brachypodium distachyon	61.31	0.0	811
LLPS-Sei-0713	Setaria italica	61.22	0.0	810
LLPS-Lep-0452	Leersia perrieri	60.57	0.0	802
LLPS-Orbr-0839	Oryza brachyantha	60.42	0.0	808
LLPS-Org-1648	Oryza glaberrima	60.12	0.0	803
LLPS-Zem-0477	Zea mays	59.61	0.0	791
LLPS-Sob-0696	Sorghum bicolor	59.46	0.0	797
LLPS-Orr-0672	Oryza rufipogon	58.93	0.0	766
LLPS-Hov-0065	Hordeum vulgare	57.89	0.0	796
LLPS-Tru-0593	Triticum urartu	56.59	0.0	629
LLPS-Orm-0082	Oryza meridionalis	55.44	0.0	684
LLPS-Ori-1050	Oryza indica	55.35	0.0	697
LLPS-Php-0354	Physcomitrella patens	48.81	0.0	652
LLPS-Ora-0048	Ornithorhynchus anatinus	43.66	2e-08	57.8
LLPS-Cis-1441	Ciona savignyi	29.81	2e-06	52.4
LLPS-Coo-0854	Colletotrichum orbiculare	28.61	7e-30	130
LLPS-Kop-0782	Komagataella pastoris	27.62	3e-06	54.7
LLPS-Pug-0360	Puccinia graminis	27.01	3e-12	73.9
LLPS-Cii-0078	Ciona intestinalis	26.62	1e-22	107
LLPS-Gaga-1565	Gallus gallus	26.01	3e-55	206
LLPS-Anc-1963	Anolis carolinensis	25.97	7e-54	202
LLPS-Scs-0144	Sclerotinia sclerotiorum	25.9	4e-38	154
LLPS-Leo-0255	Lepisosteus oculatus	25.67	4e-47	181
LLPS-Anp-0200	Anas platyrhynchos	25.66	7e-52	196
LLPS-Asni-0073	Aspergillus niger	25.55	6e-36	148
LLPS-Orn-1540	Oreochromis niloticus	25.53	2e-46	179
LLPS-Beb-0535	Beauveria bassiana	25.51	3e-32	137
LLPS-Rhb-1399	Rhinopithecus bieti	25.5	4e-54	203
LLPS-Chc-0902	Chondrus crispus	25.37	4e-25	115
LLPS-Pes-0916	Pelodiscus sinensis	25.36	9e-53	198
LLPS-Trr-0554	Trichoderma reesei	25.33	5e-36	149
LLPS-Tag-0229	Taeniopygia guttata	25.28	8e-53	198
LLPS-Scf-2377	Scleropages formosus	25.25	9e-49	186
LLPS-Fia-0720	Ficedula albicollis	25.17	4e-53	199
LLPS-Xet-0586	Xenopus tropicalis	25.07	2e-44	173
LLPS-Aim-0423	Ailuropoda melanoleuca	25.07	3e-52	197
LLPS-Man-2450	Macaca nemestrina	25.04	4e-51	193
LLPS-Mal-0438	Mandrillus leucophaeus	25.04	6e-51	193
LLPS-Mup-0717	Mustela putorius furo	25.04	4e-50	191
LLPS-Tar-2602	Takifugu rubripes	25.04	3e-44	172
LLPS-Yal-0246	Yarrowia lipolytica	25.04	2e-22	106
LLPS-Chs-0135	Chlorocebus sabaeus	25.04	5e-51	193
LLPS-Phn-1272	Phaeosphaeria nodorum	25.0	1e-17	91.3
LLPS-Trv-0659	Trichoderma virens	25.0	1e-36	150
LLPS-Nec-0018	Neurospora crassa	24.96	9e-39	157
LLPS-Mam-1748	Macaca mulatta	24.93	5e-47	181
LLPS-Scm-0744	Scophthalmus maximus	24.93	8e-45	175
LLPS-Aon-0758	Aotus nancymaae	24.89	7e-51	193
LLPS-Map-0218	Magnaporthe poae	24.86	8e-29	126
LLPS-Nol-1627	Nomascus leucogenys	24.79	5e-51	193
LLPS-Poa-3017	Pongo abelii	24.79	4e-51	194
LLPS-Pap-1474	Pan paniscus	24.79	3e-51	194
LLPS-Pat-1733	Pan troglodytes	24.79	3e-51	194
LLPS-Hos-2089	Homo sapiens	24.79	3e-51	194
LLPS-Paa-0908	Papio anubis	24.79	8e-51	193
LLPS-Gog-0224	Gorilla gorilla	24.79	3e-51	194
LLPS-Cea-0243	Cercocebus atys	24.79	1e-50	192
LLPS-Caj-0385	Callithrix jacchus	24.75	7e-50	189
LLPS-Gaa-0649	Gasterosteus aculeatus	24.72	8e-43	168
LLPS-Ved-0085	Verticillium dahliae	24.65	4e-33	140
LLPS-Icp-0610	Ictalurus punctatus	24.65	3e-47	181
LLPS-Maf-1194	Macaca fascicularis	24.65	5e-50	191
LLPS-Ast-0127	Aspergillus terreus	24.58	1e-25	117
LLPS-Bot-0981	Bos taurus	24.58	1e-46	180
LLPS-Mea-1138	Mesocricetus auratus	24.58	3e-51	194
LLPS-Orl-0050	Oryzias latipes	24.54	4e-45	175
LLPS-Myl-1022	Myotis lucifugus	24.51	2e-50	191
LLPS-Xim-0440	Xiphophorus maculatus	24.5	1e-40	162
LLPS-Eqc-0895	Equus caballus	24.43	3e-49	188
LLPS-Scp-0020	Schizosaccharomyces pombe	24.42	3e-25	115
LLPS-Cog-0122	Colletotrichum gloeosporioides	24.29	3e-36	149
LLPS-Spr-0326	Sporisorium reilianum	24.26	5e-12	73.6
LLPS-Abg-0554	Absidia glauca	24.26	1e-36	151
LLPS-Cogr-0650	Colletotrichum graminicola	24.24	2e-36	149
LLPS-Dio-1151	Dipodomys ordii	24.24	7e-47	180
LLPS-Caf-1231	Canis familiaris	24.23	5e-51	194
LLPS-Mao-0775	Magnaporthe oryzae	24.23	1e-37	153
LLPS-Pof-0939	Poecilia formosa	24.19	8e-46	177
LLPS-Scc-0474	Schizosaccharomyces cryophilus	24.19	7e-27	120
LLPS-Cas-0872	Carlito syrichta	24.18	2e-50	191
LLPS-Ict-1033	Ictidomys tridecemlineatus	24.15	9e-53	198
LLPS-Fud-0206	Fukomys damarensis	24.15	5e-48	184
LLPS-Urm-0473	Ursus maritimus	24.14	2e-50	192
LLPS-Fuv-0158	Fusarium verticillioides	24.11	9e-31	132
LLPS-Scj-0019	Schizosaccharomyces japonicus	24.09	1e-27	122
LLPS-Ran-0950	Rattus norvegicus	24.08	4e-49	187
LLPS-Dos-0042	Dothistroma septosporum	24.07	5e-32	136
LLPS-Ten-0084	Tetraodon nigroviridis	24.05	3e-41	164
LLPS-Gag-0258	Gaeumannomyces graminis	24.02	9e-31	132
LLPS-Gas-0375	Galdieria sulphuraria	23.99	1e-31	135
LLPS-Fec-1102	Felis catus	23.98	1e-49	189
LLPS-Asc-0066	Aspergillus clavatus	23.98	8e-32	135
LLPS-Cap-1098	Cavia porcellus	23.96	3e-50	191
LLPS-Sus-1255	Sus scrofa	23.94	5e-48	185
LLPS-Nef-0541	Neosartorya fischeri	23.93	2e-33	140
LLPS-Zyt-0160	Zymoseptoria tritici	23.9	1e-28	126
LLPS-Fuo-0308	Fusarium oxysporum	23.89	6e-32	136
LLPS-Ova-0295	Ovis aries	23.87	3e-46	179
LLPS-Mod-0803	Monodelphis domestica	23.85	2e-31	133
LLPS-Asm-0381	Astyanax mexicanus	23.81	2e-48	185
LLPS-Asn-0009	Aspergillus nidulans	23.76	1e-31	135
LLPS-Loa-0236	Loxodonta africana	23.73	3e-51	194
LLPS-Asfu-1292	Aspergillus fumigatus	23.71	8e-33	139
LLPS-Tum-0613	Tuber melanosporum	23.58	3e-12	73.9
LLPS-Pyt-0018	Pyrenophora teres	23.5	1e-23	110
LLPS-Asf-0745	Aspergillus flavus	23.47	3e-32	137
LLPS-Orc-1225	Oryctolagus cuniculus	23.46	2e-50	191
LLPS-Otg-0095	Otolemur garnettii	23.46	1e-48	186
LLPS-Dar-0839	Danio rerio	23.34	6e-33	139
LLPS-Miv-0494	Microbotryum violaceum	23.31	2e-10	68.2
LLPS-Mum-1325	Mus musculus	23.1	2e-50	192
LLPS-Usm-0016	Ustilago maydis	22.9	1e-13	78.6
LLPS-Fus-0342	Fusarium solani	22.79	6e-27	120
LLPS-Lem-0082	Leptosphaeria maculans	22.79	2e-21	103
LLPS-Sah-2042	Sarcophilus harrisii	22.68	4e-39	157
LLPS-Crn-0060	Cryptococcus neoformans	22.49	4e-13	77.0
LLPS-Pytr-0177	Pyrenophora triticirepentis	22.45	6e-23	108
LLPS-Blg-0721	Blumeria graminis	22.43	1e-20	100

LLPS-Viv-1178VIT_15s0048g00930

Protein Sequence

Nucleotide Sequence

LLPS-Viv-1178
VIT_15s0048g00930