• Disorder
  • Domain
  • PTM
  • Variation
  • Mutation
  • Interaction
  • Disease
  • Drug
  • Physicochemical
  • Function
  • Proteomics
  • Structure
  • Localization
  • Expression
  • Element
  • Methylation

LLPS-Urm-a789
NDUFV1

Integrated Annotations

▼ OVERVIEW


Status: Unreviewed
Protein Name: NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial
Gene Name: NDUFV1
Ensembl Gene: ENSUMAG00000013061.1
Ensembl Protein: ENSUMAP00000017768.1
Organism: Ursus maritimus
Taxa ID: 29073
LLPS Type: Others


▼ PROPERTY



——— Disorder propensity (calculated by IUPred2A)

▼ Classification


Condensates:
CondensateEvidenceOrthologs
Postsynaptic densityPredicted from orthologs(View)

▼ FUNCTION


Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain.

▼ CROSS REFERENCE


▼ SEQUENCE


Protein Sequence (FASTA)
1     MLAARRLLSG  SLPARVSVRF  SGDTTAPKKT  SFGSLKDEDR  IFTNLYGRHD  WRLKGAQSRG  60
61    DWYKTKEILL  KGPDWILGEV  KTSGLRGRGG  AGFPTGLKWS  FMNKPSDGRP  KYLVVNADEG  120
121   EPGTCKDREI  MRHDPHKLVE  GCLVGGRAMG  ARAAYIYIRG  EFYNEASNLQ  VAIREAYEAG  180
181   LIGKNACDSG  YDFDVFVVRG  AGAYICGEET  ALIESIEGKQ  GKPRLKPPFP  ADVGVFGCPT  240
241   TVANVETVAV  SPTICRRGGA  WFASFGRERN  SGTKLFNISG  HVNHPCTVEE  EMSVPLKELI  300
301   EKHAGGVIGG  WDNLLAVIPG  GSSTPLIPKS  VCETVLMDFD  ALVQAQTGLG  TAAVIVMDRS  360
361   TDVVKAIARL  IEFYKHESCG  QCTPCREGVD  WMNKVMARFV  KGDARPAEID  SLWEISKQIE  420
421   GHTICALGDG  AAWPVQGLIR  HFRPELEERM  QRFALQHQTR  QAAS  464

▼ KEYWORD


ID
Family
4Fe-4S
Complete proteome
Electron transport
Flavoprotein
FMN
Iron
Iron-sulfur
Membrane
Metal-binding
Mitochondrion
Mitochondrion inner membrane
NAD
Reference proteome
Respiratory chain
Transit peptide
Transport
Ubiquinone

▼ GENE ONTOLOGY


ID
Classification
Description
Cellular Component
Cytosol
Cellular Component
Mitochondrial respiratory chain complex I
Molecular Function
4 iron, 4 sulfur cluster binding
Molecular Function
FMN binding
Molecular Function
Metal ion binding
Molecular Function
NAD binding
Molecular Function
NADH dehydrogenase (ubiquinone) activity
Biological Process
Mitochondrial ATP synthesis coupled electron transport

▼ KEGG



▼ ORTHOLOGY


DrLLPS IDOrganismIdentityE-valueScore
LLPS-Hos-a893Homo sapiens0.0929undefined
LLPS-Mum-a880Mus musculus0.0913undefined