• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Urm-2945
NEK7

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: serine/threonine-protein kinase Nek7 isoform X1
Gene Name: NEK7
Ensembl Gene: ENSUMAG00000025364.1
Ensembl Protein: ENSUMAP00000035289.1
Organism: Ursus maritimus
Taxa ID: 29073
LLPS Type: Client


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Centrosome/Spindle pole bodyPredicted from orthologs(View)

▼ CROSS REFERENCE

▼ SEQUENCE

Protein Sequence (FASTA)
1     MDEQSQGMQG  PPVPQFQPQK  ALRPDMGYNT  LANFRIEKKI  GRGQFSEVYR  AACLLDGVPV  60
61    ALKKVQIFDL  MDAKARADCI  KEIDLLKQLN  HPNVIKYYAS  FIEDNELNIV  LELADAGDLS  120
121   RMIKHFKKQK  RLIPERTVWK  YFVQLCSALE  HMHSRRVMHR  DIKPANVFIT  ATGVVKLGDL  180
181   GLGRFFSSKT  TAAHSLVGTP  YYMSPERIHE  NGYNFKSDIW  SLGCLLYEMA  ALQSPFYGDK  240
241   MNLYSLCKKI  EQCDYPPLPS  DHYSEELRQL  VNMCINPDPE  KRPDITYVYD  VAKRMHACTA  300
301   SS  302
Nucleotide CDS Sequence (FASTA)
1     ATGGATGAAC  AATCACAAGG  AATGCAAGGG  CCACCTGTTC  CCCAGTTCCA  ACCACAGAAG  60
61    GCTTTACGAC  CGGATATGGG  CTATAATACA  TTAGCCAACT  TTCGAATAGA  AAAGAAAATT  120
121   GGTCGCGGGC  AATTTAGTGA  AGTTTATAGA  GCAGCCTGTC  TCTTGGATGG  AGTACCAGTA  180
181   GCTTTAAAAA  AAGTGCAGAT  ATTTGATTTA  ATGGATGCCA  AAGCACGTGC  TGATTGTATC  240
241   AAAGAAATAG  ATCTCCTTAA  GCAACTCAAC  CATCCAAATG  TAATTAAATA  TTATGCATCA  300
301   TTCATTGAAG  ATAATGAACT  TAACATAGTT  TTGGAATTAG  CTGATGCTGG  TGATCTATCC  360
361   AGAATGATAA  AGCATTTTAA  GAAACAAAAG  AGGCTAATTC  CTGAAAGGAC  TGTTTGGAAG  420
421   TACTTTGTTC  AACTCTGCAG  TGCGTTGGAA  CACATGCATT  CTCGACGAGT  CATGCATAGA  480
481   GATATAAAAC  CCGCTAATGT  GTTCATTACA  GCCACTGGAG  TGGTCAAACT  TGGAGATCTT  540
541   GGGCTTGGTC  GGTTTTTCAG  CTCCAAAACC  ACAGCTGCAC  ATTCTTTAGT  GGGTACACCT  600
601   TATTACATGT  CTCCAGAGAG  AATACATGAA  AATGGATACA  ACTTCAAATC  TGACATCTGG  660
661   TCTCTTGGCT  GTCTACTGTA  TGAGATGGCT  GCATTACAGA  GTCCTTTCTA  TGGTGACAAA  720
721   ATGAATTTGT  ACTCGCTGTG  TAAGAAGATA  GAACAGTGTG  ACTACCCTCC  TCTTCCTTCA  780
781   GATCACTATT  CAGAGGAACT  ACGACAGTTA  GTGAATATGT  GCATCAACCC  AGATCCAGAG  840
841   AAGCGACCAG  ACATCACCTA  CGTTTACGAC  GTAGCCAAGA  GGATGCATGC  GTGCACCGCA  900
901   AGCAGCTAA  909

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Otg-3133Otolemur garnettii100.00.0 635
LLPS-Aim-0141Ailuropoda melanoleuca100.00.0 635
LLPS-Hos-2151Homo sapiens99.670.0 634
LLPS-Pat-2168Pan troglodytes99.670.0 634
LLPS-Pap-0474Pan paniscus99.670.0 634
LLPS-Nol-3099Nomascus leucogenys99.670.0 634
LLPS-Ict-2787Ictidomys tridecemlineatus99.670.0 633
LLPS-Poa-0202Pongo abelii99.670.0 634
LLPS-Caf-2723Canis familiaris99.670.0 633
LLPS-Gog-2119Gorilla gorilla99.670.0 634
LLPS-Caj-4132Callithrix jacchus99.670.0 635
LLPS-Sus-2131Sus scrofa99.670.0 636
LLPS-Mup-1192Mustela putorius furo99.670.0 635
LLPS-Tut-0778Tursiops truncatus99.670.0 632
LLPS-Bot-4819Bos taurus99.670.0 634
LLPS-Loa-2710Loxodonta africana99.340.0 632
LLPS-Cas-2092Carlito syrichta99.340.0 632
LLPS-Fud-0208Fukomys damarensis99.340.0 632
LLPS-Sah-0476Sarcophilus harrisii99.340.0 631
LLPS-Myl-2789Myotis lucifugus99.340.0 632
LLPS-Aon-2341Aotus nancymaae99.30.0 595
LLPS-Mod-2174Monodelphis domestica99.010.0 630
LLPS-Mam-2331Macaca mulatta99.010.0 632
LLPS-Chs-3294Chlorocebus sabaeus99.010.0 632
LLPS-Maf-2972Macaca fascicularis99.010.0 632
LLPS-Mea-2666Mesocricetus auratus99.010.0 629
LLPS-Cea-2211Cercocebus atys99.010.0 632
LLPS-Ova-2607Ovis aries99.010.0 630
LLPS-Mal-4558Mandrillus leucophaeus99.010.0 632
LLPS-Paa-1651Papio anubis99.010.0 632
LLPS-Orc-2973Oryctolagus cuniculus98.680.0 624
LLPS-Dio-1879Dipodomys ordii98.680.0 630
LLPS-Fia-1631Ficedula albicollis98.340.0 622
LLPS-Anp-2007Anas platyrhynchos98.340.0 622
LLPS-Gaga-0126Gallus gallus98.340.0 622
LLPS-Tag-1969Taeniopygia guttata98.340.0 622
LLPS-Fec-2601Felis catus98.010.0 623
LLPS-Mum-3881Mus musculus98.010.0 625
LLPS-Pes-2806Pelodiscus sinensis97.020.0 617
LLPS-Meg-1244Meleagris gallopavo96.030.0 604
LLPS-Ora-2306Ornithorhynchus anatinus93.791e-109 323
LLPS-Rhb-3585Rhinopithecus bieti92.590.0 558
LLPS-Lac-3673Latimeria chalumnae91.640.0 577
LLPS-Leo-3257Lepisosteus oculatus91.120.0 571
LLPS-Xim-3632Xiphophorus maculatus90.590.0 545
LLPS-Gaa-1575Gasterosteus aculeatus90.430.0 565
LLPS-Scf-4069Scleropages formosus89.070.0 560
LLPS-Cap-4188Cavia porcellus88.740.0 546
LLPS-Ran-3012Rattus norvegicus87.350.0 608
LLPS-Xet-1523Xenopus tropicalis86.818e-180 506
LLPS-Orn-2415Oreochromis niloticus86.411e-175 496
LLPS-Ere-0212Erinaceus europaeus85.941e-158 452
LLPS-Asm-1582Astyanax mexicanus85.110.0 548
LLPS-Orl-0350Oryzias latipes84.950.0 538
LLPS-Ten-2534Tetraodon nigroviridis83.063e-64 205
LLPS-Man-2339Macaca nemestrina81.481e-177 502
LLPS-Chr-1321Chlamydomonas reinhardtii50.193e-94 291
LLPS-Tar-2282Takifugu rubripes41.272e-50 182
LLPS-Scm-0920Scophthalmus maximus40.877e-50 180
LLPS-Pof-1613Poecilia formosa40.874e-50 181
LLPS-Icp-4214Ictalurus punctatus40.871e-50 185
LLPS-Dar-0721Danio rerio40.081e-48 176
LLPS-Eqc-0654Equus caballus40.081e-49 179
LLPS-Cae-1540Caenorhabditis elegans38.711e-51 187
LLPS-Drm-0423Drosophila melanogaster37.692e-49 180
LLPS-Asg-0056Ashbya gossypii34.855e-51 179