• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Urm-1960
IDH3A

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Isocitrate dehydrogenase [NAD] subunit, mitochondrial
Gene Name: IDH3A
Ensembl Gene: ENSUMAG00000011053.1
Ensembl Protein: ENSUMAP00000015116.1
Organism: Ursus maritimus
Taxa ID: 29073
LLPS Type: LLPS regulator


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Nucleolus, P-body, Postsynaptic densityPredicted from orthologs(View)

▼ SEQUENCE

Protein Sequence (FASTA)
1     RKGRQGPPAV  PGFVSVDAAV  SRLLGAFHNQ  KQVTRGFAGG  VQTVTLIPGD  GIGPEISAAV  60
61    MKIFDAAKAP  IQWEERNVTA  IQGPGGKWMI  PPEAKESMDK  NKMGLKGPLK  TPIAAGHPSM  120
121   NLLLRKTFDL  YANVRPCVSI  EGYKTPYTDV  NIVTIRENTE  GEYSGIEHVI  VDGVVQSIKL  180
181   ITEEASRRIA  EFAFEYARSN  HRSNVTAVHK  ANIMRMSDGL  FLQKCREVAE  NCKDIKFNEM  240
241   YLDTVCLNMV  QDPSQFDVLV  MPNLYGDILS  DLCAGLIGGL  GVTPSGNIGA  NGVAIFESVH  300
301   GTAPDIAGKD  MANPTALLLS  AVMMLRHMGL  FDHAARVEAA  CFATIKDGKS  LTKDLGGNAK  360
361   CSDFTEEICR  RVRDLD  376
Nucleotide CDS Sequence (FASTA)
1     TTTGCTGGTG  GTGTTCAGAC  AGTCACTCTG  ATTCCAGGAG  ACGGCATTGG  CCCCGAGATC  60
61    TCCGCCGCAG  TGATGAAGAT  TTTTGATGCC  GCCAAAGCGC  CCATTCAGTG  GGAGGAACGG  120
121   AATGTCACCG  CCATTCAAGG  ACCTGGAGGA  AAGTGGATGA  TCCCTCCCGA  AGCCAAAGAG  180
181   TCCATGGACA  AGAACAAGAT  GGGCTTGAAA  GGCCCTTTAA  AGACCCCAAT  AGCAGCTGGC  240
241   CACCCGTCTA  TGAATCTACT  GCTGCGTAAA  ACGTTTGACC  TTTATGCCAA  TGTCCGGCCG  300
301   TGTGTCTCGA  TCGAGGGCTA  TAAAACCCCT  TACACGGACG  TGAACATCGT  CACCATCCGG  360
361   GAGAACACAG  AAGGAGAATA  CAGCGGCATT  GAGCACGTGA  TCGTCGACGG  GGTCGTGCAG  420
421   AGCATCAAGC  TCATCACCGA  GGAGGCGAGC  AGACGCATCG  CGGAGTTCGC  CTTCGAGTAC  480
481   GCCCGCAGCA  ACCACCGGAG  CAACGTCACG  GCCGTGCACA  AAGCCAACAT  CATGCGAATG  540
541   TCAGATGGGC  TTTTTCTGCA  AAAATGCAGG  GAAGTTGCTG  AAAACTGTAA  AGATATTAAA  600
601   TTTAATGAGA  TGTACCTTGA  TACAGTATGT  CTGAACATGG  TCCAGGACCC  GTCCCAGTTC  660
661   GATGTTCTTG  TTATGCCAAA  TTTGTATGGA  GACATCCTTA  GTGACCTGTG  CGCGGGACTG  720
721   ATTGGAGGTC  TTGGTGTGAC  ACCAAGTGGC  AACATTGGAG  CCAACGGGGT  CGCGATCTTC  780
781   GAGTCGGTTC  ACGGCACCGC  CCCGGACATC  GCGGGCAAGG  ACATGGCCAA  CCCCACGGCC  840
841   CTGCTGCTCA  GCGCCGTGAT  GATGCTACGC  CACATGGGGC  TTTTTGACCA  CGCCGCGAGG  900
901   GTCGAGGCCG  CGTGCTTTGC  TACGATTAAG  GATGGAAAGA  GCTTAACAAA  AGATTTAGGA  960
961   GGCAACGCAA  AGTGCTCCGA  CTTCACGGAG  GAGATCTGCC  GTCGGGTACG  AGATTTGGAT  1020
1021  TGA  1023

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Aim-3864Ailuropoda melanoleuca99.160.0 733
LLPS-Eqc-4198Equus caballus98.330.0 736
LLPS-Fud-3059Fukomys damarensis98.040.0 729
LLPS-Caj-1504Callithrix jacchus98.040.0 730
LLPS-Ict-0808Ictidomys tridecemlineatus97.770.0 732
LLPS-Pat-2909Pan troglodytes97.760.0 726
LLPS-Pap-1482Pan paniscus97.760.0 726
LLPS-Nol-3097Nomascus leucogenys97.760.0 726
LLPS-Mum-3756Mus musculus97.490.0 733
LLPS-Gog-3004Gorilla gorilla97.480.0 724
LLPS-Caf-2042Canis familiaris97.280.0 738
LLPS-Mal-1927Mandrillus leucophaeus97.210.0 727
LLPS-Ova-0161Ovis aries96.940.0 728
LLPS-Ran-0275Rattus norvegicus96.940.0 728
LLPS-Fec-2442Felis catus96.740.0 733
LLPS-Tut-0274Tursiops truncatus96.380.0 723
LLPS-Aon-1325Aotus nancymaae96.20.0 731
LLPS-Ora-2509Ornithorhynchus anatinus96.080.0 716
LLPS-Cap-1734Cavia porcellus95.880.0 728
LLPS-Orc-2509Oryctolagus cuniculus95.650.0 729
LLPS-Mam-2156Macaca mulatta95.650.0 726
LLPS-Poa-2129Pongo abelii95.650.0 727
LLPS-Cas-0535Carlito syrichta95.650.0 727
LLPS-Cea-0256Cercocebus atys95.650.0 726
LLPS-Paa-1975Papio anubis95.650.0 727
LLPS-Sah-3211Sarcophilus harrisii95.520.0 715
LLPS-Maf-0759Macaca fascicularis95.390.0 727
LLPS-Loa-1065Loxodonta africana95.380.0 728
LLPS-Hos-2390Homo sapiens95.380.0 725
LLPS-Otg-1076Otolemur garnettii95.380.0 725
LLPS-Sus-3391Sus scrofa95.380.0 727
LLPS-Chs-3535Chlorocebus sabaeus95.380.0 724
LLPS-Bot-2492Bos taurus95.110.0 727
LLPS-Man-1217Macaca nemestrina94.920.0 731
LLPS-Fia-2362Ficedula albicollis93.00.0 696
LLPS-Gaga-0879Gallus gallus92.740.0 697
LLPS-Meg-1759Meleagris gallopavo92.720.0 695
LLPS-Tag-3368Taeniopygia guttata92.720.0 693
LLPS-Mod-3908Monodelphis domestica92.450.0 713
LLPS-Rhb-2539Rhinopithecus bieti92.390.0 694
LLPS-Anp-1589Anas platyrhynchos91.990.0 694
LLPS-Myl-2374Myotis lucifugus91.60.0 664
LLPS-Anc-0323Anolis carolinensis89.760.0 630
LLPS-Pes-1731Pelodiscus sinensis88.980.0 669
LLPS-Xim-2293Xiphophorus maculatus88.060.0 627
LLPS-Orn-3574Oreochromis niloticus87.940.0 634
LLPS-Xet-0262Xenopus tropicalis86.550.0 652
LLPS-Dar-1658Danio rerio86.350.0 653
LLPS-Asm-0990Astyanax mexicanus85.930.0 605
LLPS-Leo-3746Lepisosteus oculatus85.790.0 648
LLPS-Icp-2296Ictalurus punctatus85.150.0 640
LLPS-Scm-1819Scophthalmus maximus84.940.0 634
LLPS-Scf-2898Scleropages formosus84.40.0 639
LLPS-Pof-0793Poecilia formosa84.080.0 631
LLPS-Lac-3440Latimeria chalumnae84.080.0 640
LLPS-Gaa-1528Gasterosteus aculeatus84.080.0 640
LLPS-Ten-3536Tetraodon nigroviridis83.570.0 632
LLPS-Tar-2414Takifugu rubripes83.570.0 630
LLPS-Cis-0266Ciona savignyi81.820.0 576
LLPS-Mea-1533Mesocricetus auratus75.490.0 530
LLPS-Drm-1926Drosophila melanogaster70.51e-176 504
LLPS-Cae-0306Caenorhabditis elegans70.434e-171 489
LLPS-Nef-0517Neosartorya fischeri63.583e-149 434
LLPS-Asfu-0333Aspergillus fumigatus63.581e-149 435
LLPS-Miv-1455Microbotryum violaceum63.391e-149 435
LLPS-Ved-0266Verticillium dahliae62.911e-142 417
LLPS-Put-1148Puccinia triticina62.791e-141 415
LLPS-Beb-1028Beauveria bassiana62.315e-142 416
LLPS-Gag-1285Gaeumannomyces graminis62.312e-141 414
LLPS-Map-0471Magnaporthe poae62.311e-142 417
LLPS-Mel-1121Melampsora laricipopulina62.094e-141 413
LLPS-Abg-1535Absidia glauca61.811e-152 443
LLPS-Fuo-0545Fusarium oxysporum61.721e-142 417
LLPS-Fuv-1510Fusarium verticillioides61.721e-142 417
LLPS-Blg-0823Blumeria graminis61.544e-146 427
LLPS-Fus-1587Fusarium solani61.423e-142 416
LLPS-Mao-0870Magnaporthe oryzae61.421e-140 412
LLPS-Dac-2420Daucus carota61.211e-145 424
LLPS-Crn-1109Cryptococcus neoformans60.894e-143 419
LLPS-Scp-0915Schizosaccharomyces pombe60.771e-140 412
LLPS-Usm-0232Ustilago maydis60.748e-141 413
LLPS-Sem-0514Selaginella moellendorffii60.672e-146 425
LLPS-Tum-0416Tuber melanosporum60.63e-136 401
LLPS-Ast-1286Aspergillus terreus60.55e-148 431
LLPS-Aso-1544Aspergillus oryzae60.58e-147 428
LLPS-Asf-1346Aspergillus flavus60.58e-147 428
LLPS-Scc-1454Schizosaccharomyces cryophilus60.471e-142 417
LLPS-Spr-0844Sporisorium reilianum60.466e-141 413
LLPS-Nia-2445Nicotiana attenuata60.311e-142 417
LLPS-Ori-0983Oryza indica60.23e-129 382
LLPS-Cogr-1058Colletotrichum graminicola60.065e-142 416
LLPS-Sol-2487Solanum lycopersicum60.05e-137 414
LLPS-Mua-2471Musa acuminata60.07e-142 415
LLPS-Sot-1519Solanum tuberosum60.01e-141 414
LLPS-Sei-1760Setaria italica59.944e-143 418
LLPS-Hea-1235Helianthus annuus59.887e-140 410
LLPS-Met-0351Medicago truncatula59.883e-139 408
LLPS-Php-1625Physcomitrella patens59.767e-141 413
LLPS-Amt-0264Amborella trichopoda59.692e-140 411
LLPS-Cog-1406Colletotrichum gloeosporioides59.672e-141 414
LLPS-Zem-0396Zea mays59.454e-141 413
LLPS-Chr-0435Chlamydomonas reinhardtii59.412e-144 420
LLPS-Viv-2013Vitis vinifera59.382e-140 411
LLPS-Tra-1989Triticum aestivum59.382e-140 411
LLPS-Nec-1524Neurospora crassa59.365e-145 424
LLPS-Bro-1396Brassica oleracea59.332e-142 416
LLPS-Brn-1996Brassica napus59.332e-142 416
LLPS-Zyt-1339Zymoseptoria tritici59.271e-140 412
LLPS-Gas-0704Galdieria sulphuraria59.211e-141 414
LLPS-Sob-2545Sorghum bicolor59.156e-141 412
LLPS-Asn-1117Aspergillus nidulans59.125e-146 426
LLPS-Asc-1478Aspergillus clavatus59.081e-146 428
LLPS-Coo-1178Colletotrichum orbiculare59.044e-142 416
LLPS-Pytr-1014Pyrenophora triticirepentis59.031e-142 417
LLPS-Phn-0370Phaeosphaeria nodorum59.031e-142 417
LLPS-Pyt-0913Pyrenophora teres59.032e-142 417
LLPS-Brr-2643Brassica rapa59.025e-142 416
LLPS-Mae-0137Manihot esculenta59.05e-144 421
LLPS-Dos-1244Dothistroma septosporum58.931e-137 405
LLPS-Org-0702Oryza glaberrima58.848e-130 383
LLPS-Orbr-1000Oryza brachyantha58.812e-142 416
LLPS-Glm-1114Glycine max58.648e-139 407
LLPS-Prp-1099Prunus persica58.534e-143 419
LLPS-Orp-0391Oryza punctata58.516e-142 415
LLPS-Ors-0396Oryza sativa58.511e-141 414
LLPS-Orm-2128Oryza meridionalis58.511e-141 414
LLPS-Orr-1559Oryza rufipogon58.511e-141 414
LLPS-Orb-1213Oryza barthii58.511e-141 414
LLPS-Orni-1454Oryza nivara58.519e-141 414
LLPS-Orgl-0655Oryza glumaepatula58.511e-140 414
LLPS-Trv-0806Trichoderma virens58.452e-140 412
LLPS-Asni-0678Aspergillus niger58.387e-146 428
LLPS-Tru-1194Triticum urartu58.218e-142 415
LLPS-Hov-1278Hordeum vulgare58.212e-141 414
LLPS-Brd-0345Brachypodium distachyon58.211e-141 414
LLPS-Trr-1051Trichoderma reesei58.177e-141 413
LLPS-Gor-1088Gossypium raimondii58.111e-143 419
LLPS-Coc-2134Corchorus capsularis57.866e-141 412
LLPS-Via-0564Vigna angularis57.862e-139 409
LLPS-Vir-1861Vigna radiata57.572e-139 408
LLPS-Yal-0729Yarrowia lipolytica57.36e-137 402
LLPS-Phv-0526Phaseolus vulgaris57.271e-138 407
LLPS-Cus-1235Cucumis sativus57.271e-138 407
LLPS-Lep-1017Leersia perrieri56.982e-142 416
LLPS-Kop-0650Komagataella pastoris56.87e-129 382
LLPS-Thc-2285Theobroma cacao56.642e-139 409
LLPS-Asg-0949Ashbya gossypii56.053e-122 365
LLPS-Arl-2043Arabidopsis lyrata55.771e-141 414
LLPS-Pot-2638Populus trichocarpa55.651e-142 417
LLPS-Art-2009Arabidopsis thaliana55.295e-133 393
LLPS-Chc-0265Chondrus crispus55.293e-131 388
LLPS-Sac-1587Saccharomyces cerevisiae55.192e-119 358
LLPS-Cym-1008Cyanidioschyzon merolae50.04e-116 350
LLPS-Cii-0426Ciona intestinalis48.12e-98 305
LLPS-Mup-0647Mustela putorius furo45.951e-91 287
LLPS-Orl-0101Oryzias latipes45.376e-93 291