• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Urm-1697
LOC103680817

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: ubiquitin-like modifier-activating enzyme 1
Gene Name: LOC103680817
Ensembl Gene: ENSUMAG00000000648.1
Ensembl Protein: ENSUMAP00000002639.1
Organism: Ursus maritimus
Taxa ID: 29073
LLPS Type: LLPS regulator


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Nucleolus, Stress granule, Postsynaptic densityPredicted from orthologs(View)

▼ SEQUENCE

Protein Sequence (FASTA)
1     AKPLYDQLQV  GEFCHSRGIK  LVVADTRGLF  GQLFCDFGEE  MILTDSNGEQ  PLSAMVSMVT  60
61    KDSPGVVTCL  DEARHGFESG  DFVSFTEVQG  MHELNGTYPI  EIKVLGPYTF  SICDTSSFSE  120
121   YIRGGIVSQV  KVPKKISFKS  LPASLAEPDF  VITDFAKYSR  PGQLHIGFQA  LHHFCAQHGR  180
181   APRPHNEEDA  TELVTLAQAV  NARALPAVQQ  DILDEDLIRK  LSYVAAGDLA  PINAFIGGLA  240
241   AQEVMKACSG  KFMPVMQWLY  FDALECLPED  KQALTEDKCL  PCQNRYDGQV  AVFGSDLQEK  300
301   LGKQKYFLVG  AGAIGCELLK  NFAMIGLGCG  EDGAVTVTDM  DTIEKSNLNR  QFLFRPWDVT  360
361   KLKSDTAAAA  VRHINPYIRV  MSHQNCVGPD  TEHIYDDSFF  QNLDGVANAL  DNVDTRMYMD  420
421   RHCVYYRKPL  LESGTLGTKG  NVQVVIPFLT  ESYSSSQDPP  EKSIPICTLK  NFPNAIEHTL  480
481   QWARDEFEGL  FKQPAENVNQ  YLTDSNFVER  TLCLAGTQPL  EMLEAVQRSL  VLQRPHTWAD  540
541   CVTWAYHHWH  TQYSNNIRQL  LHNFPPDQLT  SSGALFWSGP  KRCPHPLIFD  VNNPLHLDYV  600
601   MAAANLFAQT  YGLMGSQDRA  AVAILLQSVH  IPEFTPRSDV  KIHVSDQELQ  NSSASVAPFH  660
661   LPPVQSAAFS  SDPGLDLKGL  TCLSFPTDDS  CIQELKAMLP  SPEKLPGFKM  YPINFEKDDN  720
721   TNFHMDFIVA  ASNLRAENYN  IPPADRHKSK  MIAGKIIPAI  ATTTAAIVGL  VCLELYKVVQ  780
781   GHRQLESYKN  SFMNLALPFF  SFSEPLAPPR  HQYCNQEWTL  WDRFEVQGLQ  PNGEEMTLKQ  840
841   FLNYFKTEHK  LEITMLSQGV  SMLYSFFMPA  TKLRERLDQP  VTEIVSRVSQ  RKLDHHVRAL  900
901   VLELCCNDET  GEDVEVPYVR  YTIR  924
Nucleotide CDS Sequence (FASTA)
1     GCTAAGCCTT  TGTATGACCA  GCTGCAGGTG  GGTGAGTTCT  GTCATAGCCG  TGGAATCAAG  60
61    CTGGTCGTGG  CAGACACACG  AGGCCTATTT  GGGCAGTTGT  TTTGTGACTT  TGGAGAGGAA  120
121   ATGATCCTTA  CAGATTCCAA  TGGGGAGCAG  CCGCTCAGTG  CTATGGTATC  TATGGTTACA  180
181   AAGGATAGCC  CTGGTGTTGT  CACCTGCCTG  GATGAGGCCC  GGCATGGATT  TGAGAGCGGC  240
241   GACTTTGTCT  CCTTCACAGA  AGTCCAAGGC  ATGCATGAAC  TCAACGGCAC  CTACCCCATA  300
301   GAGATCAAAG  TCCTGGGTCC  CTATACCTTT  AGTATCTGTG  ACACTTCTAG  CTTCTCTGAG  360
361   TATATCCGGG  GAGGTATTGT  CAGTCAGGTT  AAAGTACCTA  AGAAGATCAG  CTTTAAATCC  420
421   TTGCCAGCCT  CACTGGCAGA  GCCAGACTTT  GTGATAACGG  ATTTTGCCAA  GTATTCTCGC  480
481   CCTGGTCAGC  TGCACATTGG  CTTCCAGGCC  CTGCACCACT  TCTGTGCTCA  GCATGGCCGG  540
541   GCCCCTCGGC  CCCACAATGA  GGAGGATGCA  ACAGAACTGG  TGACCTTAGC  ACAGGCTGTG  600
601   AATGCCCGAG  CCCTGCCAGC  AGTGCAGCAG  GACATCCTGG  ATGAGGACCT  CATTCGAAAG  660
661   CTGTCATATG  TGGCTGCTGG  GGATCTGGCA  CCCATAAACG  CCTTTATTGG  GGGCTTGGCT  720
721   GCTCAGGAAG  TTATGAAGGC  CTGCTCTGGG  AAGTTTATGC  CTGTTATGCA  GTGGCTGTAC  780
781   TTTGATGCCC  TTGAGTGTCT  CCCTGAGGAC  AAACAGGCCC  TCACAGAGGA  CAAGTGTCTC  840
841   CCGTGCCAGA  ACCGTTATGA  TGGGCAGGTG  GCTGTATTTG  GCTCAGACCT  GCAAGAGAAG  900
901   CTGGGCAAGC  AAAAGTACTT  CTTGGTGGGT  GCAGGGGCCA  TTGGCTGTGA  ACTCCTCAAG  960
961   AACTTTGCCA  TGATTGGTCT  AGGCTGTGGG  GAGGATGGAG  CAGTCACTGT  TACTGACATG  1020
1021  GACACCATTG  AGAAGTCCAA  TCTCAACCGA  CAGTTTTTGT  TCCGGCCCTG  GGATGTCACG  1080
1081  AAGTTGAAAT  CTGACACAGC  TGCTGCAGCT  GTGCGCCACA  TAAATCCGTA  CATCCGGGTA  1140
1141  ATGAGCCATC  AGAATTGTGT  TGGCCCTGAC  ACAGAGCATA  TCTATGACGA  CAGCTTCTTC  1200
1201  CAGAACCTCG  ATGGTGTTGC  CAATGCCCTG  GACAATGTGG  ATACTCGCAT  GTACATGGAC  1260
1261  CGCCACTGCG  TGTACTACCG  TAAACCACTG  CTGGAGTCAG  GCACGCTGGG  CACCAAGGGC  1320
1321  AATGTGCAGG  TGGTTATCCC  CTTCCTGACA  GAGTCCTACA  GCTCCAGCCA  GGACCCTCCT  1380
1381  GAGAAGTCCA  TCCCCATCTG  CACACTGAAG  AACTTCCCCA  ATGCCATCGA  ACACACATTG  1440
1441  CAGTGGGCTC  GGGATGAGTT  TGAAGGTCTC  TTCAAGCAGC  CAGCAGAAAA  TGTCAACCAG  1500
1501  TATCTCACAG  ACTCCAATTT  TGTGGAACGG  ACACTGTGCC  TGGCAGGTAC  CCAACCCCTG  1560
1561  GAGATGCTGG  AGGCTGTGCA  GCGTAGCCTG  GTGCTACAGC  GGCCACACAC  CTGGGCTGAC  1620
1621  TGTGTGACCT  GGGCTTACCA  CCACTGGCAC  ACTCAGTACT  CCAACAACAT  TCGCCAGCTT  1680
1681  TTGCACAACT  TTCCACCTGA  CCAGCTTACA  AGCTCTGGAG  CCCTATTCTG  GTCTGGGCCC  1740
1741  AAACGCTGTC  CACACCCACT  CATCTTTGAT  GTCAACAATC  CCCTACATCT  GGATTATGTG  1800
1801  ATGGCTGCTG  CCAACCTCTT  TGCCCAGACC  TATGGGCTGA  TGGGGTCTCA  GGACCGAGCT  1860
1861  GCTGTGGCCA  TACTTCTACA  GTCTGTGCAC  ATCCCTGAAT  TCACCCCCAG  GTCTGATGTC  1920
1921  AAGATTCATG  TCTCTGACCA  GGAGCTTCAG  AACTCCAGTG  CCTCTGTTGG  TGAGGATGAT  1980
1981  AGTTGCATAC  AGGAGCTCAA  AGCCATGCTT  CCCAGCCCAG  AGAAGCTCCC  TGGGTTCAAG  2040
2041  ATGTACCCTA  TCAACTTTGA  GAAGGATGAT  AATACCAACT  TTCATATGGA  TTTCATTGTG  2100
2101  GCTGCATCCA  ACCTCCGAGC  AGAAAACTAT  AACATTCCCC  CTGCAGATCG  GCATAAGAGC  2160
2161  AAGATGATTG  CAGGGAAGAT  CATCCCTGCT  ATTGCCACAA  CGACAGCAGC  TATAGTTGGC  2220
2221  CTCGTGTGTC  TGGAGCTATA  CAAAGTGGTG  CAGGGACACC  GGCAGCTTGA  ATCTTATAAG  2280
2281  AACAGCTTTA  TGAACTTGGC  CCTGCCCTTC  TTCAGCTTCT  CTGAACCTCT  TGCCCCACCC  2340
2341  CGTCACCAGT  ACTGTAACCA  AGAGTGGACA  TTGTGGGATC  GCTTTGAGGT  ACAGGGGCTA  2400
2401  CAGCCTAATG  GTGAAGAGAT  GACTCTCAAA  CAGTTCCTTA  ACTATTTTAA  GACAGAGCAC  2460
2461  AAATTAGAGA  TTACCATGCT  GTCCCAAGGT  GTATCCATGC  TGTACTCCTT  TTTCATGCCA  2520
2521  GCTACCAAAC  TCAGGGAACG  GTTGGATCAG  CCGGTGACAG  AAATTGTGAG  CCGTGTGTCA  2580
2581  CAGCGAAAGC  TGGACCACCA  TGTGCGGGCA  CTGGTGCTTG  AGCTATGCTG  CAATGATGAG  2640
2641  ACTGGCGAGG  ATGTCGAAGT  TCCCTATGTA  CGATACACCA  TCCGCTGA  2688

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Sus-4404Sus scrofa88.290.01662
LLPS-Ova-3293Ovis aries88.180.01669
LLPS-Bot-0699Bos taurus87.960.01661
LLPS-Eqc-1601Equus caballus87.850.01652
LLPS-Fec-0301Felis catus87.850.01652
LLPS-Paa-2264Papio anubis87.850.01652
LLPS-Mal-4063Mandrillus leucophaeus87.850.01653
LLPS-Cea-2431Cercocebus atys87.850.01653
LLPS-Aon-0039Aotus nancymaae87.840.01650
LLPS-Man-2999Macaca nemestrina87.740.01652
LLPS-Otg-2447Otolemur garnettii87.740.01651
LLPS-Maf-1323Macaca fascicularis87.740.01651
LLPS-Caj-1989Callithrix jacchus87.740.01653
LLPS-Mam-0117Macaca mulatta87.640.01650
LLPS-Pat-0549Pan troglodytes87.640.01650
LLPS-Pap-2916Pan paniscus87.640.01650
LLPS-Rhb-0284Rhinopithecus bieti87.640.01649
LLPS-Mea-0578Mesocricetus auratus87.640.01645
LLPS-Nol-0948Nomascus leucogenys87.530.01643
LLPS-Chs-3536Chlorocebus sabaeus87.530.01645
LLPS-Gog-1529Gorilla gorilla87.530.01649
LLPS-Hos-0784Homo sapiens87.420.01648
LLPS-Ran-1303Rattus norvegicus87.420.01647
LLPS-Ict-2049Ictidomys tridecemlineatus87.310.01645
LLPS-Cas-1187Carlito syrichta87.310.01647
LLPS-Tut-1525Tursiops truncatus87.310.01640
LLPS-Mup-1319Mustela putorius furo87.20.01640
LLPS-Poa-0570Pongo abelii87.090.01630
LLPS-Cap-1140Cavia porcellus86.880.01641
LLPS-Orc-0479Oryctolagus cuniculus86.660.01637
LLPS-Aim-1805Ailuropoda melanoleuca86.590.01631
LLPS-Dio-1694Dipodomys ordii86.550.01635
LLPS-Mum-3139Mus musculus86.230.01628
LLPS-Fud-1296Fukomys damarensis86.230.01630
LLPS-Myl-0766Myotis lucifugus86.120.01622
LLPS-Mod-2062Monodelphis domestica80.760.01531
LLPS-Sah-0054Sarcophilus harrisii80.260.01529
LLPS-Scf-0803Scleropages formosus75.460.01438
LLPS-Lac-0388Latimeria chalumnae74.950.01452
LLPS-Leo-0741Lepisosteus oculatus74.620.01430
LLPS-Dar-2419Danio rerio74.080.01416
LLPS-Anc-3078Anolis carolinensis74.00.01431
LLPS-Orn-1446Oreochromis niloticus73.860.01403
LLPS-Asm-0045Astyanax mexicanus73.80.01405
LLPS-Scm-0632Scophthalmus maximus73.540.01391
LLPS-Orl-0548Oryzias latipes73.10.01395
LLPS-Icp-0744Ictalurus punctatus73.020.01389
LLPS-Pof-3796Poecilia formosa72.890.01390
LLPS-Ten-1089Tetraodon nigroviridis72.670.01360
LLPS-Xim-0674Xiphophorus maculatus72.560.01367
LLPS-Tar-2394Takifugu rubripes72.130.01357
LLPS-Gaa-0167Gasterosteus aculeatus71.040.01339
LLPS-Cii-1906Ciona intestinalis58.970.01116
LLPS-Cis-0304Ciona savignyi58.60.01097
LLPS-Xet-0388Xenopus tropicalis56.350.0 968
LLPS-Drm-0624Drosophila melanogaster56.30.01041
LLPS-Abg-1718Absidia glauca55.290.01039
LLPS-Usm-0733Ustilago maydis52.140.0 923
LLPS-Crn-0437Cryptococcus neoformans52.130.0 940
LLPS-Spr-1209Sporisorium reilianum51.920.0 916
LLPS-Ast-0251Aspergillus terreus51.770.0 938
LLPS-Scs-0444Sclerotinia sclerotiorum51.730.0 919
LLPS-Nec-0241Neurospora crassa51.670.0 923
LLPS-Asg-0356Ashbya gossypii51.460.0 930
LLPS-Mel-1104Melampsora laricipopulina51.40.0 927
LLPS-Scj-0360Schizosaccharomyces japonicus51.250.0 934
LLPS-Aso-0068Aspergillus oryzae51.240.0 923
LLPS-Asf-0761Aspergillus flavus51.240.0 922
LLPS-Mao-0543Magnaporthe oryzae51.240.0 910
LLPS-Tum-0630Tuber melanosporum51.130.0 892
LLPS-Scc-1422Schizosaccharomyces cryophilus51.030.0 884
LLPS-Asn-0775Aspergillus nidulans50.970.0 919
LLPS-Fuv-0224Fusarium verticillioides50.960.0 857
LLPS-Dos-0564Dothistroma septosporum50.920.0 912
LLPS-Gag-0478Gaeumannomyces graminis50.860.0 911
LLPS-Asc-0582Aspergillus clavatus50.860.0 916
LLPS-Asni-0705Aspergillus niger50.810.0 926
LLPS-Nef-0413Neosartorya fischeri50.760.0 907
LLPS-Ved-0609Verticillium dahliae50.750.0 887
LLPS-Asfu-1243Aspergillus fumigatus50.750.0 909
LLPS-Map-0988Magnaporthe poae50.750.0 902
LLPS-Blg-0241Blumeria graminis50.70.0 905
LLPS-Cog-0458Colletotrichum gloeosporioides50.650.0 896
LLPS-Miv-0552Microbotryum violaceum50.650.0 900
LLPS-Put-0902Puccinia triticina50.610.0 896
LLPS-Trv-0076Trichoderma virens50.590.0 890
LLPS-Zyt-1268Zymoseptoria tritici50.490.0 907
LLPS-Trr-0614Trichoderma reesei50.480.0 904
LLPS-Fus-0348Fusarium solani50.430.0 900
LLPS-Coo-0477Colletotrichum orbiculare50.380.0 899
LLPS-Cogr-0540Colletotrichum graminicola50.320.0 903
LLPS-Phn-1135Phaeosphaeria nodorum50.270.0 905
LLPS-Yal-0594Yarrowia lipolytica50.270.0 886
LLPS-Scp-0642Schizosaccharomyces pombe50.220.0 901
LLPS-Pug-0018Puccinia graminis50.170.0 897
LLPS-Pyt-1272Pyrenophora teres49.730.0 896
LLPS-Lem-0266Leptosphaeria maculans49.730.0 892
LLPS-Kop-0894Komagataella pastoris49.510.0 884
LLPS-Sac-1553Saccharomyces cerevisiae49.410.0 897
LLPS-Fuo-0009Fusarium oxysporum49.190.0 552
LLPS-Chc-0439Chondrus crispus48.90.0 846
LLPS-Pytr-0661Pyrenophora triticirepentis48.790.0 887
LLPS-Beb-1514Beauveria bassiana48.280.0 867
LLPS-Fia-2890Ficedula albicollis47.050.0 744
LLPS-Meg-3345Meleagris gallopavo46.70.0 668
LLPS-Cae-0154Caenorhabditis elegans46.550.0 789
LLPS-Gas-0105Galdieria sulphuraria45.070.0 831
LLPS-Mae-1807Manihot esculenta44.120.0 730
LLPS-Loa-0042Loxodonta africana43.890.0 691
LLPS-Cym-0655Cyanidioschyzon merolae43.790.0 729
LLPS-Chr-1117Chlamydomonas reinhardtii43.720.0 709
LLPS-Php-0674Physcomitrella patens43.520.0 739
LLPS-Sol-0552Solanum lycopersicum43.50.0 726
LLPS-Mua-0509Musa acuminata43.380.0 729
LLPS-Bro-3052Brassica oleracea43.360.0 733
LLPS-Arl-1870Arabidopsis lyrata43.360.0 745
LLPS-Sem-0128Selaginella moellendorffii43.180.0 728
LLPS-Pot-2274Populus trichocarpa43.150.0 748
LLPS-Amt-0712Amborella trichopoda43.140.0 732
LLPS-Art-2502Arabidopsis thaliana43.110.0 742
LLPS-Viv-2007Vitis vinifera43.028e-32 136
LLPS-Sot-0399Solanum tuberosum42.960.0 717
LLPS-Sei-0913Setaria italica42.930.0 734
LLPS-Ere-0735Erinaceus europaeus42.840.0 606
LLPS-Org-0963Oryza glaberrima42.730.0 724
LLPS-Osl-0752Ostreococcus lucimarinus42.670.0 734
LLPS-Lep-0592Leersia perrieri42.660.0 724
LLPS-Orm-1072Oryza meridionalis42.640.0 726
LLPS-Orp-2354Oryza punctata42.640.0 729
LLPS-Orbr-2045Oryza brachyantha42.640.0 724
LLPS-Hea-1208Helianthus annuus42.610.0 750
LLPS-Anp-1364Anas platyrhynchos42.590.0 662
LLPS-Orni-1765Oryza nivara42.530.0 728
LLPS-Sob-0810Sorghum bicolor42.50.0 728
LLPS-Gaga-3804Gallus gallus42.490.0 658
LLPS-Brd-2170Brachypodium distachyon42.490.0 722
LLPS-Tru-0928Triticum urartu42.460.0 717
LLPS-Tra-2595Triticum aestivum42.460.0 717
LLPS-Ors-0546Oryza sativa42.430.0 723
LLPS-Orb-0814Oryza barthii42.430.0 722
LLPS-Hov-0950Hordeum vulgare42.380.0 719
LLPS-Gor-1953Gossypium raimondii42.370.0 713
LLPS-Zem-0186Zea mays42.350.0 723
LLPS-Brn-1491Brassica napus42.311e-32 139
LLPS-Thc-1282Theobroma cacao42.270.0 714
LLPS-Nia-1304Nicotiana attenuata42.210.0 721
LLPS-Orr-0302Oryza rufipogon42.120.0 718
LLPS-Ori-0604Oryza indica42.120.0 718
LLPS-Coc-0562Corchorus capsularis42.110.0 735
LLPS-Dac-0856Daucus carota42.060.0 729
LLPS-Orgl-0779Oryza glumaepatula42.010.0 715
LLPS-Prp-0664Prunus persica41.790.0 724
LLPS-Brr-2110Brassica rapa41.762e-32 138
LLPS-Via-1052Vigna angularis41.670.0 702
LLPS-Vir-1478Vigna radiata41.670.0 706
LLPS-Tag-3426Taeniopygia guttata41.560.0 645
LLPS-Phv-1334Phaseolus vulgaris41.560.0 701
LLPS-Glm-0620Glycine max41.550.0 709
LLPS-Cus-0533Cucumis sativus41.530.0 711
LLPS-Met-1278Medicago truncatula41.272e-31 135
LLPS-Pes-2675Pelodiscus sinensis41.190.0 634
LLPS-Caf-4293Canis familiaris41.130.0 629
LLPS-Ora-2908Ornithorhynchus anatinus40.720.0 585