LLPS-Urm-1588
PKP4
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | plakophilin-4 isoform X1 |
| Gene Name: | PKP4 |
| Ensembl Gene: | ENSUMAG00000005676.1 |
| Ensembl Protein: | ENSUMAP00000007317.1 |
| Organism: | Ursus maritimus |
| Taxa ID: | 29073 |
| LLPS Type: | Others |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Centrosome/Spindle pole body, Postsynaptic density | Predicted from orthologs | (View) |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSUMAT00000008778.1 | ENSUMAP00000007317.1 |
| Ensembl | ENSUMAT00000008805.1 | ENSUMAP00000007341.1 |
| Ensembl | ENSUMAT00000008785.1 | ENSUMAP00000007323.1 |
| UniProt | A0A384BSL7, A0A384BSL7_URSMA | |
| RefSeq | , XM_008687002.1 | , XP_008685224.1, XP_008685224.1 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MPTPEQASLV EERQPQTCQE AASTGPGMEP ETTATTILAS VKEQELQFQR LTRELEVERQ 60 61 IVASQLERCR LGAESPSIAS TSSTEKSFPW RSTGPHPCTV ECVPECHSFP RCPLKSLSCD 120 121 VPNTGVNKPR VSDAVHPNNY LIRTEPEQGT LYSPEQTSLH ERSLGNSRSS TQMNSYSDSG 180 181 YQEAGSFHNS QNLSKAENRP QHSFIGSTNN HLVRNSRAEG QTLVQPSVAN RAMRRVSSVP 240 241 SRAQSPSYVI STGVSPSRGS LRTSLGSGFG SPSVTDSRPL NPSAYSSTTL PAQRAASPYS 300 301 AQRPASPTAV RRIGSVTSRQ TSNPNGPTPQ YQTTTRVGSP LTLMDAQTRV ASPSQGQVGS 360 361 SSPKRSGMTA VPQHLGPSLQ RTVHDMEQFG QQQYEIYERM VPPRPDSLTG LRSSYASQHS 420 421 QLGQDLRSAV SPDLHITPIY EGRTYYSPVY RSPNHGTVEL QGSQTALYRT GSVGVGNLQR 480 481 TSSQRSTLTY QRNNYALNTT ATYAEPYRPI QYRVQECNYN RLQHAVPADD GTTRSPSIDS 540 541 IQKDPREFAW RDPELPEVIH MLQHQFPSVQ ANAAAYLQHL CFGDNKVKME VCRLGGIKHL 600 601 VDLLDHRVLE VQKNACGALR NLVFGKSTDE NKIAMKNVGG IPALLRLLRK SIDAEVRELV 660 661 TGVLWNLSSC DAVKMTIIRD ALSTLTNTVI VPHSGWNNSS FDDDHKIKFQ TSLVLRNTTG 720 721 CLRNLSSAGE EARKQMRSCE GLVDSLLYVI HTCVNTSDYD SKTVENCVCT LRNLSYRLEL 780 781 EVPQARLLGL SELDDLLGKE SPSKDSEPSC WGKKKKKKKR TPQEDQWDGV GPIPGLSKSP 840 841 KGVEMLWHPS VVKPYLTLLA ESSNPATLEG SAGSLQNLSA GNWKFAAYIR AAVRKEKGLP 900 901 ILVELLRMDN DRVVSSVATA LRNMALDVRN KELIGKYAMR DLVNRLPGGT GPSVLSDETM 960 961 AAICCALHEV TSKNMENAKA LADSGGIEKL VNITKGRGDR SSLKVVKAAA QVLNTLWQYR 1020 1021 DLRSIYKKDG WNQNHFITPV STLERDRFKS HPSLSTTNQQ MSPIIQSVGS TSSSPALLGI 1080 1081 RDPRSEYDRT QPPMQYYNSQ GDATHKGLYP GSSKPSPIYI SSYSSPAREQ NRRLQHQQLY 1140 1141 YSQDDSNRKN FDAYRLYLQS PHSYEDPYFD DRVHFPASTD YSTQYGLKST TNYVDFYSTK 1200 1201 RPSYRAEQYP GSPDSWV 1217 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGCCCACTC CTGAGCAGGC CTCATTGGTG GAGGAGAGGC AACCACAGAC CTGCCAGGAA 60 61 GCTGCCTCCA CTGGCCCAGG CATGGAACCC GAGACCACAG CCACCACTAT TCTAGCTTCC 120 121 GTGAAGGAGC AGGAACTTCA GTTTCAACGA CTCACCCGAG AACTGGAAGT GGAAAGGCAG 180 181 ATCGTTGCCA GTCAGCTAGA GAGATGTAGG CTCGGAGCAG AATCCCCAAG TATCGCCAGC 240 241 ACCAGCTCAA CTGAGAAGTC GTTTCCTTGG AGATCAACAG GGCCACACCC GTGTACTGTG 300 301 GAATGTGTAC CGGAGTGCCA CAGTTTCCCA CGCTGTCCAT TGAAATCATT GTCGTGTGAT 360 361 GTGCCAAATA CTGGTGTAAA CAAACCTAGA GTTTCTGACG CTGTCCACCC CAACAACTAT 420 421 CTCATCAGGA CAGAGCCAGA ACAGGGGACC CTCTATTCAC CAGAACAGAC ATCTCTCCAT 480 481 GAAAGATCAT TGGGTAACTC AAGAAGTTCA ACACAAATGA ATTCTTATTC TGACAGTGGA 540 541 TACCAGGAAG CAGGGAGTTT CCACAACAGC CAGAATTTGA GTAAAGCAGA AAACAGACCG 600 601 CAGCATTCAT TCATAGGCTC AACTAATAAC CATTTGGTGA GGAATTCAAG AGCTGAAGGA 660 661 CAAACACTGG TTCAGCCATC AGTAGCCAAT CGGGCCATGA GAAGAGTTAG TTCAGTTCCA 720 721 TCTAGAGCAC AGTCTCCTTC TTATGTTATC AGCACAGGCG TGTCTCCTTC AAGGGGGTCA 780 781 CTGAGAACTT CTCTGGGTAG TGGATTTGGC TCTCCGTCAG TGACCGACTC CCGACCACTG 840 841 AACCCCAGTG CGTATTCCTC CACCACATTA CCTGCTCAGC GGGCAGCCTC TCCGTACTCT 900 901 GCACAGAGAC CCGCCTCCCC AACAGCTGTA CGGCGGATTG GGTCAGTCAC CTCCCGGCAG 960 961 ACCTCCAATC CCAACGGACC AACCCCTCAG TACCAAACTA CCACAAGAGT AGGGTCCCCA 1020 1021 CTGACCCTGA TGGATGCACA GACTCGAGTA GCTTCCCCAT CCCAAGGCCA GGTGGGGTCG 1080 1081 TCGTCCCCCA AACGCTCAGG GATGACCGCC GTACCACAAC ATCTGGGACC TTCACTGCAA 1140 1141 AGGACTGTTC ACGACATGGA ACAATTTGGA CAGCAGCAGT ATGAAATTTA TGAAAGAATG 1200 1201 GTTCCACCTC GGCCAGACAG CCTGACAGGC TTACGGAGTT CCTATGCTAG TCAGCATAGC 1260 1261 CAGCTTGGGC AAGACCTTCG TTCAGCTGTG TCTCCTGACT TGCACATCAC TCCTATATAT 1320 1321 GAGGGGAGGA CCTATTACAG CCCAGTGTAC CGCAGCCCAA ACCATGGGAC CGTGGAGCTC 1380 1381 CAAGGATCAC AGACAGCACT GTACCGCACA GGCTCAGTAG GTGTTGGAAA TCTGCAAAGG 1440 1441 ACATCCAGCC AACGAAGCAC CCTTACATAC CAAAGAAATA ATTATGCTCT GAACACAACA 1500 1501 GCTACCTACG CAGAACCCTA CAGGCCAATA CAGTACCGAG TGCAAGAGTG CAATTATAAC 1560 1561 AGGCTTCAGC ACGCAGTGCC AGCCGATGAT GGTACCACAA GATCCCCGTC AATAGACAGC 1620 1621 ATTCAGAAAG ACCCGAGGGA GTTCGCCTGG CGTGACCCGG AGCTGCCCGA AGTCATCCAC 1680 1681 ATGCTGCAGC ACCAGTTCCC GTCGGTCCAG GCGAACGCAG CCGCCTACCT GCAGCACCTG 1740 1741 TGCTTTGGTG ACAACAAAGT GAAAATGGAG GTGTGTAGGT TAGGGGGAAT CAAGCATCTG 1800 1801 GTTGACCTTT TGGACCACAG AGTTTTGGAA GTTCAGAAGA ATGCTTGTGG TGCCCTCCGA 1860 1861 AACCTTGTTT TTGGCAAGTC TACAGATGAA AATAAAATAG CAATGAAGAA TGTTGGTGGG 1920 1921 ATACCTGCCT TGTTGCGACT GTTAAGAAAA TCTATTGATG CAGAAGTAAG GGAGCTTGTT 1980 1981 ACAGGAGTTC TTTGGAATTT ATCTTCATGT GATGCTGTAA AGATGACAAT CATTCGAGAT 2040 2041 GCTCTCTCAA CCTTAACAAA CACTGTGATC GTTCCACATT CTGGGTGGAA TAACTCTTCT 2100 2101 TTTGATGATG ATCATAAAAT TAAATTTCAG ACATCACTCG TTCTACGTAA TACGACAGGT 2160 2161 TGCCTGAGGA ACCTCAGCTC TGCGGGGGAG GAAGCCAGGA AGCAAATGCG CTCCTGCGAG 2220 2221 GGGCTGGTGG ACTCGCTGCT GTACGTGATC CACACGTGTG TGAACACCTC CGATTACGAC 2280 2281 AGCAAGACTG TGGAGAACTG CGTGTGCACC CTGAGGAACC TGTCCTATCG GCTGGAACTG 2340 2341 GAGGTCCCAC AGGCCCGGCT GCTGGGGCTG AGTGAGCTGG ATGACTTACT AGGAAAAGAG 2400 2401 TCTCCCAGCA AGGACTCGGA GCCAAGCTGC TGGGGGAAGA AAAAGAAAAA GAAAAAGAGA 2460 2461 ACACCCCAAG AGGATCAATG GGATGGAGTT GGTCCTATCC CAGGACTGTC AAAGTCCCCC 2520 2521 AAAGGGGTTG AGATGCTGTG GCATCCATCA GTGGTAAAAC CATATCTGAC TCTTCTAGCA 2580 2581 GAAAGTTCCA ACCCAGCCAC CTTGGAAGGC TCTGCCGGAT CGCTCCAGAA CCTCTCTGCT 2640 2641 GGAAACTGGA AGTTTGCAGC GTACATCCGG GCAGCTGTCC GCAAAGAAAA AGGGCTCCCC 2700 2701 ATCCTTGTAG AACTTCTGAG AATGGATAAT GATAGAGTCG TTTCTTCGGT GGCAACTGCC 2760 2761 TTGAGGAATA TGGCGCTAGA TGTTCGCAAC AAGGAGCTCA TAGGTAAATA TGCCATGCGA 2820 2821 GACCTGGTCA ACCGGCTTCC CGGCGGCACC GGCCCCAGTG TGCTGTCTGA TGAGACCATG 2880 2881 GCGGCCATCT GCTGTGCTCT GCATGAGGTC ACCAGCAAAA ACATGGAGAA CGCCAAAGCT 2940 2941 CTGGCCGACT CAGGGGGGAT AGAGAAGCTG GTGAACATAA CCAAGGGCAG AGGAGACAGA 3000 3001 TCATCTCTGA AAGTGGTGAA GGCAGCAGCC CAGGTCTTGA ATACATTATG GCAGTATCGG 3060 3061 GACCTCCGGA GCATTTATAA AAAGGATGGG TGGAATCAGA ACCATTTCAT TACACCTGTG 3120 3121 TCGACGTTAG AGCGAGACCG ATTCAAATCA CATCCTTCCT TGTCTACCAC CAACCAACAG 3180 3181 ATGTCACCCA TCATTCAGTC AGTTGGCAGC ACCTCCTCCT CACCAGCACT GTTAGGAATC 3240 3241 AGAGACCCTC GCTCTGAGTA CGATAGGACC CAGCCACCTA TGCAGTATTA CAATAGCCAA 3300 3301 GGGGACGCCA CACATAAAGG CCTGTACCCT GGCTCCAGCA AACCTTCACC AATTTACATC 3360 3361 AGTTCCTATT CCTCACCAGC AAGAGAACAA AATAGACGGC TACAGCATCA ACAGCTGTAT 3420 3421 TATAGTCAAG ATGACTCCAA CAGAAAGAAC TTTGATGCAT ACAGATTGTA TTTGCAATCT 3480 3481 CCTCATAGCT ATGAAGATCC TTATTTTGAT GACCGAGTTC ACTTTCCAGC TTCTACTGAT 3540 3541 TATTCAACAC AGTATGGACT GAAATCAACC ACAAATTATG TAGACTTTTA TTCCACGAAA 3600 3601 CGACCTTCTT ATAGAGCAGA ACAGTACCCA GGGTCCCCAG ACTCATGGGT GTAG 3654 |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Bot-1324 | Bos taurus | 98.18 | 0.0 | 2068 |
| LLPS-Otg-2854 | Otolemur garnettii | 97.36 | 0.0 | 2047 |
| LLPS-Fec-1509 | Felis catus | 97.13 | 0.0 | 2258 |
| LLPS-Caf-4462 | Canis familiaris | 96.72 | 0.0 | 2251 |
| LLPS-Mup-1737 | Mustela putorius furo | 96.64 | 0.0 | 2252 |
| LLPS-Pap-0440 | Pan paniscus | 96.06 | 0.0 | 2229 |
| LLPS-Gog-2384 | Gorilla gorilla | 95.98 | 0.0 | 2228 |
| LLPS-Sus-3022 | Sus scrofa | 95.92 | 0.0 | 2145 |
| LLPS-Ova-4106 | Ovis aries | 95.9 | 0.0 | 2234 |
| LLPS-Aon-2256 | Aotus nancymaae | 95.9 | 0.0 | 2226 |
| LLPS-Rhb-4230 | Rhinopithecus bieti | 95.9 | 0.0 | 2226 |
| LLPS-Cea-3060 | Cercocebus atys | 95.89 | 0.0 | 2231 |
| LLPS-Nol-2192 | Nomascus leucogenys | 95.89 | 0.0 | 2219 |
| LLPS-Chs-2133 | Chlorocebus sabaeus | 95.82 | 0.0 | 2225 |
| LLPS-Maf-1627 | Macaca fascicularis | 95.82 | 0.0 | 2225 |
| LLPS-Ict-0669 | Ictidomys tridecemlineatus | 95.73 | 0.0 | 2215 |
| LLPS-Mam-0531 | Macaca mulatta | 95.73 | 0.0 | 2224 |
| LLPS-Poa-0987 | Pongo abelii | 95.73 | 0.0 | 2221 |
| LLPS-Pat-0221 | Pan troglodytes | 95.73 | 0.0 | 2217 |
| LLPS-Mal-1534 | Mandrillus leucophaeus | 95.65 | 0.0 | 2215 |
| LLPS-Orc-2692 | Oryctolagus cuniculus | 95.65 | 0.0 | 2219 |
| LLPS-Paa-4128 | Papio anubis | 95.57 | 0.0 | 2214 |
| LLPS-Hos-2329 | Homo sapiens | 95.57 | 0.0 | 2207 |
| LLPS-Caj-4765 | Callithrix jacchus | 95.48 | 0.0 | 2206 |
| LLPS-Loa-3083 | Loxodonta africana | 95.32 | 0.0 | 2220 |
| LLPS-Fud-0726 | Fukomys damarensis | 94.84 | 0.0 | 2201 |
| LLPS-Man-0807 | Macaca nemestrina | 94.83 | 0.0 | 2189 |
| LLPS-Eqc-3211 | Equus caballus | 94.81 | 0.0 | 2220 |
| LLPS-Aim-3657 | Ailuropoda melanoleuca | 94.73 | 0.0 | 1192 |
| LLPS-Dio-2536 | Dipodomys ordii | 94.18 | 0.0 | 2179 |
| LLPS-Cap-4063 | Cavia porcellus | 94.09 | 0.0 | 2176 |
| LLPS-Ran-1351 | Rattus norvegicus | 93.6 | 0.0 | 2160 |
| LLPS-Mum-3230 | Mus musculus | 93.6 | 0.0 | 2162 |
| LLPS-Mea-0306 | Mesocricetus auratus | 93.6 | 0.0 | 2166 |
| LLPS-Mod-1008 | Monodelphis domestica | 92.38 | 0.0 | 1974 |
| LLPS-Ora-2259 | Ornithorhynchus anatinus | 92.37 | 0.0 | 1856 |
| LLPS-Sah-3260 | Sarcophilus harrisii | 90.5 | 0.0 | 2119 |
| LLPS-Anp-2650 | Anas platyrhynchos | 88.22 | 0.0 | 2053 |
| LLPS-Pes-2916 | Pelodiscus sinensis | 87.5 | 0.0 | 2041 |
| LLPS-Anc-3432 | Anolis carolinensis | 87.48 | 0.0 | 2026 |
| LLPS-Meg-0149 | Meleagris gallopavo | 87.25 | 0.0 | 2019 |
| LLPS-Gaga-3467 | Gallus gallus | 87.17 | 0.0 | 2019 |
| LLPS-Fia-2183 | Ficedula albicollis | 87.02 | 0.0 | 1483 |
| LLPS-Tag-1603 | Taeniopygia guttata | 84.53 | 0.0 | 1944 |
| LLPS-Xet-3195 | Xenopus tropicalis | 79.02 | 0.0 | 1838 |
| LLPS-Lac-3451 | Latimeria chalumnae | 77.95 | 0.0 | 1796 |
| LLPS-Leo-3691 | Lepisosteus oculatus | 74.37 | 0.0 | 1699 |
| LLPS-Icp-3703 | Ictalurus punctatus | 68.5 | 0.0 | 1328 |
| LLPS-Asm-3247 | Astyanax mexicanus | 67.66 | 0.0 | 1494 |
| LLPS-Orn-1360 | Oreochromis niloticus | 67.28 | 0.0 | 1472 |
| LLPS-Tar-3175 | Takifugu rubripes | 66.56 | 0.0 | 1457 |
| LLPS-Scm-3317 | Scophthalmus maximus | 66.24 | 0.0 | 1456 |
| LLPS-Gaa-2432 | Gasterosteus aculeatus | 66.11 | 0.0 | 1449 |
| LLPS-Scf-2709 | Scleropages formosus | 64.7 | 0.0 | 1418 |
| LLPS-Ten-3504 | Tetraodon nigroviridis | 64.46 | 0.0 | 1362 |
| LLPS-Orl-3091 | Oryzias latipes | 64.04 | 0.0 | 1394 |
| LLPS-Dar-2206 | Danio rerio | 60.73 | 0.0 | 1270 |
| LLPS-Xim-2616 | Xiphophorus maculatus | 58.86 | 0.0 | 1110 |
| LLPS-Pof-3759 | Poecilia formosa | 56.09 | 0.0 | 1145 |
| LLPS-Cas-3272 | Carlito syrichta | 47.71 | 3e-136 | 447 |
| LLPS-Tut-2379 | Tursiops truncatus | 34.2 | 2e-79 | 284 |