LLPS-Tar-a230
AK1
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | Adenylate kinase isoenzyme 1 |
| Gene Name: | AK1, ak1 |
| Ensembl Gene: | ENSTRUG00000006830.2 |
| Ensembl Protein: | ENSTRUP00000016776.2 |
| Organism: | Takifugu rubripes |
| Taxa ID: | 31033 |
| LLPS Type: | Client |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Postsynaptic density | Predicted from orthologs | (View) |
▼ FUNCTION
| Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Also displays broad nucleoside diphosphate kinase activity. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSTRUT00000016849.2 | ENSTRUP00000016776.2 |
| UniProt | H2SWI8, H2SWI8_TAKRU | |
| Entrez | 101064020 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MIKDFSFFLF YYNKIKDAKI IFVVGGPGSG KGTQCEKIVA KYGYTHLSSG DLLRAEVASG 60 61 SERGKQLQAI MQKGELVPLD TVLDMIKDAM IAKADVSKGF LIDGYPREVK QGEEFEKKIG 120 121 KPCLLLYVDA RGETMVKRLM KRGETSGRSD DNEETIKKRL DLYYKATEPV IAFYENRGIV 180 181 RKVDSELPVD EVFGQVSKVI DALQ 204 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGGCAGACA AAATTAAAGA TGCCAAGATC ATCTTTGTCG TGGGTGGGCC TGGTTCTGGA 60 61 AAGGGCACTC AGTGTGAGAA AATAGTTGCA AAGTATGGCT ACACCCATCT GTCATCCGGG 120 121 GATCTGCTCC GTGCTGAAGT GGCCTCTGGC TCCGAGAGGG GCAAGCAGCT CCAGGCCATC 180 181 ATGCAGAAGG GAGAGCTTGT TCCCCTGGAC ACCGTCTTAG ACATGATTAA GGATGCCATG 240 241 ATCGCCAAGG CCGACGTGTC CAAGGGCTTC CTCATTGACG GCTACCCCCG TGAGGTGAAG 300 301 CAGGGCGAGG AGTTTGAGAA GAAGGAACCG CGGCCACTGG GTGACTTTGA AACTACAGCT 360 361 TGTCCTCTTT CGCTGCAGAT CGGCAAACCC TGCCTGCTGC TGTACGTTGA CGCCAGAGGG 420 421 GAGACCATGG TCAAGAGGCT TATGAAGCGC GGCGAGACCA GCGGACGCTC GGACGACAAC 480 481 GAGGAGACCA TCAAGAAGCG CCTGGACTTG TATTACAAAG CGACCGAGCC TGTCATTGCC 540 541 TTCTACGAGA ACCGTGGCAT TGTCAGAAAG GTCGACTCCG AGCTGCCCGT GGACGAGGTT 600 601 TTCGGTCAAT TCCATTTTCA CAGCCTGTTT CGTAAGAGCA GATCATTA 648 |
▼ KEYWORD
▼ GENE ONTOLOGY
ID | Classification | Description |
Cellular Component | Cytoplasm | |
Molecular Function | Adenylate kinase activity | |
Molecular Function | ATP binding | |
Molecular Function | Nucleoside diphosphate kinase activity | |
Biological Process | ADP biosynthetic process | |
Biological Process | AMP metabolic process | |
Biological Process | ATP metabolic process | |
Biological Process | Nucleoside triphosphate biosynthetic process |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Hos-a274 | Homo sapiens | 2e-102 | 303 | undefined |
| LLPS-Mum-a273 | Mus musculus | 4e-104 | 308 | undefined |