• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Tar-3145
mark3

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Non-specific serine/threonine protein kinase
Gene Name: mark3
Ensembl Gene: ENSTRUG00000006908.2
Ensembl Protein: ENSTRUP00000016963.2
Organism: Takifugu rubripes
Taxa ID: 31033
LLPS Type: LLPS regulator


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Postsynaptic density, OthersPredicted from orthologs(View)

▼ SEQUENCE

Protein Sequence (FASTA)
1     MSTKTPLPTV  NEKVTESHTT  HTNGRQEIGT  RSARTGVRSR  SSEEPQQPHV  GNYRLLKTIG  60
61    KGNFAKVKLA  RHILTGREVA  IKIIDKTQLN  PNSLQKLFRE  VRIMKILNHP  NIVKLFEVIE  120
121   TERTLYLVME  YASGGEVFDY  LVAHGRMKEK  EARAKFRQIV  SAVQYCHQKH  IVHRDLKAEN  180
181   LLLDADMNIK  IADFGFSNEF  TLGNKLDTFC  GSPPYAAPEL  FQGKKYDGPE  VDVWSLGVIL  240
241   YTLVSGSLPF  DGQNLKELRE  RVLRGKYRIP  FYMSTDCENL  LKRFLVLNPS  KRGTLEQIMK  300
301   DRWINTGFEE  DELKPYTEPE  LDITDQKRID  VMVGMGYNLE  DIQDSLAKMK  YDEITATYLL  360
361   LGRKASELEP  TESASSSNLS  LAKPRPNSEL  NGQSPTHIKV  QRSISSSHKQ  RRYSEQVGQN  420
421   VPPGMAHPKR  SQTSTADNSA  KEEGGVQLRK  PGTPGSRGAP  PSSPLLGNAN  NPNKADIPDR  480
481   RKGVATGPSN  NPASAGMTRR  NTYVCSDRNN  ADRLSVIPNG  KENSSVAVSP  SAQRNPVASI  540
541   HSIANATTPD  RLRFPRGTAS  RSTFHGGHLR  DRRTATYNGP  PASPTLSHDA  TPLSQTRSRG  600
601   TSNLFSKLTS  KLTRRNMSFR  FTKSRHVPGD  QKGESKDGKP  RSLRFTWSMR  TTSSMEPCDI  660
661   MREIRKVLDA  NNCDYEQQES  FLLLCVHGDG  RAENLVQWEM  EVCKLPRLSL  NG  712
Nucleotide CDS Sequence (FASTA)
1     ATGTCAACAA  AAACTCCTTT  ACCGACGGTC  AACGAAAAGG  TGACGGAAAG  TCACACGACG  60
61    CACACTAATG  GCCGCCAGGA  GATCGGAACG  CGCTCCGCCA  GGACCGGCGT  CCGATCCCGG  120
121   AGCTCCGAGG  AGCCGCAGCA  GCCTCACGTG  GGCAACTACC  GGCTGCTCAA  GACCATCGGA  180
181   AAGGGCAACT  TTGCCAAGGT  CAAGCTGGCT  CGGCACATCC  TCACAGGCAG  AGAGGTGGCA  240
241   ATAAAGATAA  TAGACAAGAC  CCAGCTGAAC  CCAAACAGCC  TTCAGAAGGT  AATTCGCCTC  300
301   CTCCTCGTCA  AACTCTTTGA  AGTGATCGAG  ACTGAGAGGA  CACTTTACCT  GGTGATGGAG  360
361   TACGCCAGTG  GAGGAGAAGT  GTTTGACTAC  CTGGTCGCAC  ATGGAAGAAT  GAAGGAAAAA  420
421   GAGGCCAGGG  CTAAATTTAG  ACAGATCGTA  TCGGCGGTGC  AGTATTGTCA  CCAGAAGCAC  480
481   ATCGTTCACC  GAGACCTGAA  GGCTGAAAAC  CTTCTGCTGG  ATGCAGACAT  GAACATCAAG  540
541   ATAGCAGATT  TTGGCTTCAG  TAATGAGTTC  ACACTGGGTA  ACAAGCTGGA  CACGTTCTGT  600
601   GGTTCGCCGC  CTTACGCTGC  GCCGGAGCTC  TTTCAGGGAA  AGAAGTACGA  CGGGCCGGAA  660
661   GTGGACGTCT  GGAGTCTGGG  GGTCATCCTG  TACACACTGG  TCAGCGGCTC  GCTCCCTTTT  720
721   GATGGGCAGA  ACCTCAAGGA  GCTACGGGAG  CGTGTGCTCA  GAGGAAAGTA  CAGAATCCCC  780
781   TTCTACATGT  CCACAGACTG  CGAGAACTTG  CTCAAGCGCT  TCCTGGTGCT  CAACCCGTCC  840
841   AAGCGGGGCA  CTCTCGAGCA  AATTATGAAG  GATCGATGGA  TCAACACAGG  ATTTGAGGAG  900
901   GACGAGCTGA  AGCCTTACAC  CGAGCCAGAG  CTGGACATCA  CAGACCAGAA  GAGAATAGAT  960
961   GTGATGGTGG  GAATGGGCTA  CAACCTGGAG  GATATCCAGG  ACTCTCTGGC  CAAGATGAAG  1020
1021  TATGATGAGA  TCACAGCCAC  CTACCTGCTG  CTGGGCAGGA  AGGCCTCTGA  GCTGGAGCCC  1080
1081  ACTGAGTCGG  CCTCTAGCAG  CAACTTATCT  CTGGCCAAAC  CGAGACCCAA  CAGCGAGCTG  1140
1141  AACGGCCAGT  CGCCGACCCA  CATCAAAGTC  CAGAGGAGCA  TTTCCTCCAG  TCACAAACAG  1200
1201  AGACGCTACA  GCGAGCAAGT  TGGTCAGAAC  GTTCCTCCAG  GAATGGCTCA  CCCAAAGAGG  1260
1261  AGTCAGACCT  CGACGGCGGA  CAACAGCGCC  AAGGAAGAAG  GCGGCGTGCA  GCTCCGTAAG  1320
1321  CCCGGCACCC  CGGGGAGCCG  AGGTGCCCCT  CCCTCCAGCC  CTCTGCTGGG  CAACGCCAAC  1380
1381  AACCCCAACA  AGGCCGACAT  CCCAGACCGC  AGGAAAGGTG  TCGCCACCGG  CCCGAGCAAT  1440
1441  AACCCGGCAT  CTGCAGGTAT  GACCAGGAGG  AACACGTACG  TGTGCAGCGA  CCGAAACAAC  1500
1501  GCGGATCGAC  TCTCCGTCAT  CCCCAACGGG  AAGGAGAACA  GCGCCCAGAG  GAATCCAGTG  1560
1561  GCGTCGATCC  ACAGCATCGC  CAACGCCACC  ACGCCGGACC  GCCTGCGTTT  CCCACGAGGC  1620
1621  ACCGCCAGCC  GCAGCACCTT  CCACGGCGGG  CACCTGAGAG  ACCGGCGCAC  CGCCACATAC  1680
1681  AACGGGCCGC  CGGCCTCACC  CACTCTCTCC  CACGATGCCA  CCCCCCTGTC  ACAGACTCGC  1740
1741  AGCCGTGGAA  CCAGCAACCT  TTTCTCCAAA  CTGACCTCCA  AACTCACCCG  CAGTCGCCAT  1800
1801  GTACCTGGGG  ATCAAAAAGG  GGAAAGTAAA  GACGGTAAAC  CCCGCTCCCT  CAGATTCACT  1860
1861  TGGAGTATGA  GGACCACCAG  CTCCATGGAG  CCCTGCGACA  TCATGAGGGA  GATTCGCAAG  1920
1921  GTGCTCGACG  CCAACAACTG  CGACTACGAA  CAACAAGAGA  GTTTCCTGCT  TCTTTGCGTC  1980
1981  CACGGAGACG  GGCGCGCCGA  AAACCTGGTC  CAGTGGGAGA  TGGAGGTCTG  CAAGCTTCCC  2040
2041  CGAAGGTCTT  GTTGTCGTTG  TGCCTTCAGA  AGGATTTCAG  TTACTTCCTA  G  2091

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Orl-3491Oryzias latipes90.230.01332
LLPS-Scm-3270Scophthalmus maximus85.480.01332
LLPS-Xim-1478Xiphophorus maculatus80.820.01074
LLPS-Cii-0600Ciona intestinalis80.09e-179 520
LLPS-Ora-1247Ornithorhynchus anatinus79.890.01147
LLPS-Scf-0257Scleropages formosus79.760.01191
LLPS-Orc-4371Oryctolagus cuniculus78.780.01149
LLPS-Caj-0594Callithrix jacchus78.50.01145
LLPS-Cas-2479Carlito syrichta78.440.01145
LLPS-Fud-3976Fukomys damarensis77.870.01113
LLPS-Cae-0220Caenorhabditis elegans77.636e-33 140
LLPS-Gaga-2857Gallus gallus76.130.01159
LLPS-Icp-1528Ictalurus punctatus75.060.01124
LLPS-Xet-3697Xenopus tropicalis74.90.01103
LLPS-Sah-3083Sarcophilus harrisii74.770.01129
LLPS-Lac-3387Latimeria chalumnae74.680.01131
LLPS-Tag-3412Taeniopygia guttata74.650.01129
LLPS-Sus-4776Sus scrofa74.140.01129
LLPS-Fia-3418Ficedula albicollis74.120.0 981
LLPS-Mea-0081Mesocricetus auratus73.850.01097
LLPS-Mum-4163Mus musculus73.680.01113
LLPS-Mod-1446Monodelphis domestica73.470.01139
LLPS-Ict-0973Ictidomys tridecemlineatus73.340.01113
LLPS-Ran-3852Rattus norvegicus73.270.01098
LLPS-Cap-3083Cavia porcellus73.160.01112
LLPS-Meg-2502Meleagris gallopavo72.720.01078
LLPS-Ere-0560Erinaceus europaeus71.150.0 658
LLPS-Dio-4294Dipodomys ordii70.780.0 889
LLPS-Drm-0398Drosophila melanogaster66.773e-154 471
LLPS-Mup-3382Mustela putorius furo66.250.0 797
LLPS-Dar-3056Danio rerio65.930.0 784
LLPS-Anp-2229Anas platyrhynchos65.590.0 917
LLPS-Ten-3415Tetraodon nigroviridis64.950.0 932
LLPS-Bot-2437Bos taurus64.660.0 839
LLPS-Caf-1580Canis familiaris64.510.0 834
LLPS-Eqc-3133Equus caballus64.510.0 837
LLPS-Cea-2813Cercocebus atys64.510.0 837
LLPS-Leo-2397Lepisosteus oculatus63.679e-113 369
LLPS-Tut-1365Tursiops truncatus63.360.0 896
LLPS-Urm-0247Ursus maritimus62.982e-100 330
LLPS-Mal-4054Mandrillus leucophaeus62.820.0 918
LLPS-Poa-2253Pongo abelii62.80.0 767
LLPS-Loa-1496Loxodonta africana62.390.0 796
LLPS-Otg-3161Otolemur garnettii62.380.0 845
LLPS-Hos-2414Homo sapiens62.250.0 845
LLPS-Pap-4698Pan paniscus62.250.0 845
LLPS-Pat-3865Pan troglodytes62.250.0 845
LLPS-Mam-4391Macaca mulatta62.120.0 844
LLPS-Maf-0103Macaca fascicularis62.120.0 844
LLPS-Aon-3096Aotus nancymaae62.120.0 845
LLPS-Paa-0834Papio anubis62.120.0 844
LLPS-Chs-2132Chlorocebus sabaeus61.910.0 852
LLPS-Fec-0779Felis catus61.850.0 842
LLPS-Man-1023Macaca nemestrina61.30.0 822
LLPS-Ova-4269Ovis aries60.850.0 813
LLPS-Asm-2647Astyanax mexicanus60.550.0 818
LLPS-Pes-1866Pelodiscus sinensis60.520.0 822
LLPS-Orn-1882Oreochromis niloticus60.380.0 831
LLPS-Gaa-0756Gasterosteus aculeatus60.110.0 820
LLPS-Myl-3319Myotis lucifugus59.950.0 813
LLPS-Aim-0216Ailuropoda melanoleuca59.860.0 810
LLPS-Rhb-3507Rhinopithecus bieti58.850.0 837
LLPS-Nol-2324Nomascus leucogenys58.770.0 833
LLPS-Gog-1134Gorilla gorilla58.640.0 829
LLPS-Anc-2478Anolis carolinensis57.820.0 791
LLPS-Pof-2941Poecilia formosa57.620.0 792
LLPS-Cis-1457Ciona savignyi51.118e-98 317
LLPS-Kop-0972Komagataella pastoris47.02e-88 294
LLPS-Yal-0727Yarrowia lipolytica46.52e-87 292
LLPS-Orbr-0158Oryza brachyantha45.713e-89 295
LLPS-Sei-0362Setaria italica45.052e-86 288
LLPS-Nia-2028Nicotiana attenuata44.799e-89 294
LLPS-Blg-0735Blumeria graminis44.517e-89 301
LLPS-Phn-1502Phaeosphaeria nodorum44.352e-86 285
LLPS-Dos-1280Dothistroma septosporum44.234e-88 301
LLPS-Arl-1065Arabidopsis lyrata44.082e-87 290
LLPS-Art-2601Arabidopsis thaliana43.798e-88 291
LLPS-Bro-1072Brassica oleracea43.531e-86 288
LLPS-Lep-2156Leersia perrieri43.343e-89 295
LLPS-Beb-0941Beauveria bassiana42.585e-87 295
LLPS-Sol-1999Solanum lycopersicum42.499e-88 291
LLPS-Scs-0667Sclerotinia sclerotiorum42.421e-87 296
LLPS-Orm-0713Oryza meridionalis42.274e-90 297
LLPS-Ors-2364Oryza sativa41.999e-90 296
LLPS-Orr-1376Oryza rufipogon41.999e-90 296
LLPS-Orb-2279Oryza barthii41.991e-89 297
LLPS-Orni-0188Oryza nivara41.993e-89 298
LLPS-Orgl-0300Oryza glumaepatula41.992e-89 299
LLPS-Sob-2229Sorghum bicolor41.938e-87 288
LLPS-Zem-1597Zea mays40.538e-88 298
LLPS-Sac-0308Saccharomyces cerevisiae40.368e-88 295
LLPS-Nec-0056Neurospora crassa39.953e-87 296
LLPS-Tra-2482Triticum aestivum39.083e-86 287