• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Tar-2114
mbnl2a

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Muscleblind-like protein 2a
Gene Name: mbnl2a
Ensembl Gene: ENSTRUG00000010220.2
Ensembl Protein: ENSTRUP00000054881.1
Organism: Takifugu rubripes
Taxa ID: 31033
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Nuclear speckle, P-body, Stress granulePredicted from orthologs(View)

▼ SEQUENCE

Protein Sequence (FASTA)
1     MALNIASIRD  TKWLTLEVCR  QFQRGTCSRS  DEECKFAHPP  KSCQVENGRV  IACFDSLKGR  60
61    CTRENCKYLH  PPAHLKTQLE  INGRNNLIQQ  KTAAAMLAQQ  MQFMIPSTTM  QHVQTFPVNQ  120
121   GLGSSAGLSY  TPYLTPMSHS  MGLVPTDILP  STPVIVPGSP  PVSVTAGSSS  NQKLLRTDKL  180
181   EVCREFQRGN  CARGETDCRF  AHPSDSPMID  TSDNTVTVCM  DYIKSRCSRE  KCKYFHPPAH  240
241   LQAKVKAAQH  QANQTAVAAQ  AAATAAAMTQ  STAKAMKRPL  EATVDLAFPH  SGLQPLPKRP  300
301   ALEKSNGSSS  LFNPSVLHYQ  QALANAQLQQ  PAFFPTGSVL  CMTPASSLDH  PEVSLRKEME  360
361   CHNTTLGNPK  QPLCKYYLTS  PLEIQQPAC  389
Nucleotide CDS Sequence (FASTA)
1     ATGGCTCTAA  ATATTGCATC  GATAAGGGAC  ACAAAATGGC  TGACCCTGGA  AGTGTGCAGG  60
61    CAGTTTCAGA  GAGGAACTTG  TTCACGCAGC  GATGAAGAGT  GCAAATTTGC  CCACCCTCCT  120
121   AAAAGTTGCC  AGGTGGAGAA  TGGAAGAGTA  ATTGCCTGTT  TTGACTCTTT  AAAGGGGCGC  180
181   TGCACACGAG  AGAACTGCAA  ATACCTCCAC  CCACCTGCTC  ACCTGAAGAC  CCAGCTGGAG  240
241   ATCAATGGGA  GAAATAACCT  AATCCAGCAG  AAGACAGCGG  CGGCCATGTT  GGCTCAACAG  300
301   ATGCAGTTTA  TGATCCCCAG  CACCACCATG  CAGCATGTGC  AGACGTTTCC  AGTGAACCAA  360
361   GGTCTGGGTT  CCAGTGCAGG  TTTGAGCTAT  ACACCATACC  TGACCCCCAT  GTCCCACAGC  420
421   ATGGGCCTGG  TCCCCACAGA  TATCCTGCCC  AGCACCCCAG  TTATTGTCCC  TGGCAGTCCT  480
481   CCTGTTTCTG  TCACTGCTGG  CTCATCATCC  AACCAGAAGC  TCCTGCGCAC  AGACAAATTA  540
541   GAGGTTTGCC  GCGAGTTCCA  ACGGGGAAAC  TGCGCTCGAG  GTGAGACTGA  CTGTCGTTTT  600
601   GCCCACCCGA  GTGACAGCCC  CATGATTGAC  ACCAGCGACA  ACACGGTCAC  TGTCTGCATG  660
661   GACTACATCA  AGAGCCGCTG  CTCTCGTGAG  AAGTGCAAAT  ACTTTCACCC  CCCAGCCCAC  720
721   CTACAGGCCA  AAGTTAAGGC  TGCACAACAC  CAGGCCAATC  AGACGGCTGT  GGCCGCCCAA  780
781   GCTTTCCCCC  ACAGTGGCCT  CCAGCCCCTA  CCAAAGAGAC  CAGCACTTGA  GAAGAGTAAT  840
841   GGATCGAGCT  CCCTGTTCAA  TCCCAGTGTT  TTGCACTACC  AGCAGGCGCT  GGCCAACGCA  900
901   CAGCTCCAGC  AGCCAGCGTT  CTTCCCAACA  GTCCCAATGA  TGTACAGTGC  TACGCCTGCT  960
961   ACTGTCTCTG  CAGCAACAAC  TCCTGCCACA  AGTGTCCCCT  ACGCAGCAAC  AGCACCAGCC  1020
1021  AATCAGGTTT  GCTCCTTTTA  A  1041

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Orn-1242Oreochromis niloticus97.990.0 535
LLPS-Xim-1270Xiphophorus maculatus94.340.0 588
LLPS-Orl-0579Oryzias latipes94.340.0 586
LLPS-Scm-1496Scophthalmus maximus92.540.0 573
LLPS-Dar-1683Danio rerio90.286e-166 477
LLPS-Pof-3262Poecilia formosa88.170.0 555
LLPS-Leo-1686Lepisosteus oculatus85.962e-165 476
LLPS-Scf-2180Scleropages formosus83.080.0 531
LLPS-Gaa-2561Gasterosteus aculeatus81.751e-174 498
LLPS-Lac-2099Latimeria chalumnae79.068e-148 432
LLPS-Ora-1582Ornithorhynchus anatinus78.08e-152 441
LLPS-Gaga-1456Gallus gallus77.437e-154 447
LLPS-Anp-0237Anas platyrhynchos77.434e-154 447
LLPS-Xet-2230Xenopus tropicalis77.142e-155 451
LLPS-Meg-1493Meleagris gallopavo77.142e-153 447
LLPS-Mod-0905Monodelphis domestica76.888e-151 439
LLPS-Poa-2350Pongo abelii76.03e-154 447
LLPS-Cea-1351Cercocebus atys76.03e-154 447
LLPS-Caj-4237Callithrix jacchus76.03e-154 447
LLPS-Gog-0067Gorilla gorilla75.942e-149 435
LLPS-Paa-2821Papio anubis75.718e-154 447
LLPS-Fud-0645Fukomys damarensis75.713e-153 445
LLPS-Orc-3722Oryctolagus cuniculus75.438e-154 447
LLPS-Ran-4105Rattus norvegicus75.01e-147 430
LLPS-Anc-2900Anolis carolinensis74.583e-106 323
LLPS-Mum-1216Mus musculus74.577e-153 444
LLPS-Sah-2958Sarcophilus harrisii74.536e-138 406
LLPS-Chs-3479Chlorocebus sabaeus74.214e-144 421
LLPS-Caf-3209Canis familiaris73.641e-143 420
LLPS-Mea-1033Mesocricetus auratus73.381e-97 301
LLPS-Myl-3681Myotis lucifugus73.354e-143 419
LLPS-Man-2815Macaca nemestrina71.682e-162 469
LLPS-Pap-0706Pan paniscus71.682e-162 469
LLPS-Pat-2819Pan troglodytes71.682e-162 469
LLPS-Aon-0419Aotus nancymaae71.682e-162 469
LLPS-Eqc-3862Equus caballus70.922e-161 466
LLPS-Fec-2427Felis catus70.666e-161 465
LLPS-Sus-0840Sus scrofa70.661e-161 467
LLPS-Tag-2032Taeniopygia guttata70.594e-154 447
LLPS-Fia-1464Ficedula albicollis70.594e-154 447
LLPS-Urm-0736Ursus maritimus70.21e-147 430
LLPS-Bot-0672Bos taurus70.152e-159 461
LLPS-Hos-2766Homo sapiens70.082e-152 442
LLPS-Pes-1192Pelodiscus sinensis69.824e-152 442
LLPS-Ict-2075Ictidomys tridecemlineatus69.577e-152 441
LLPS-Tut-0279Tursiops truncatus69.577e-152 441
LLPS-Nol-0899Nomascus leucogenys69.496e-151 439
LLPS-Aim-2102Ailuropoda melanoleuca69.317e-151 439
LLPS-Cap-1675Cavia porcellus69.053e-151 440
LLPS-Rhb-1151Rhinopithecus bieti69.051e-151 441
LLPS-Mal-0407Mandrillus leucophaeus69.059e-152 441
LLPS-Ova-3019Ovis aries69.045e-118 355
LLPS-Icp-0634Ictalurus punctatus67.353e-152 442
LLPS-Mup-1162Mustela putorius furo66.673e-141 414
LLPS-Otg-3080Otolemur garnettii66.412e-141 414
LLPS-Loa-3893Loxodonta africana66.332e-150 437
LLPS-Mam-3767Macaca mulatta65.912e-127 380
LLPS-Maf-4122Macaca fascicularis65.912e-127 380
LLPS-Cae-1125Caenorhabditis elegans64.714e-34 134
LLPS-Cas-1216Carlito syrichta64.632e-86 273
LLPS-Ten-0351Tetraodon nigroviridis64.259e-143 419
LLPS-Cii-1465Ciona intestinalis62.677e-28 110
LLPS-Asm-1788Astyanax mexicanus59.195e-123 369
LLPS-Sem-1297Selaginella moellendorffii47.766e-1270.9