LLPS-Tar-1868
parp1
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | Poly [ADP-ribose] polymerase |
| Gene Name: | parp1 |
| Ensembl Gene: | ENSTRUG00000014490.2 |
| Ensembl Protein: | ENSTRUP00000037062.2 |
| Organism: | Takifugu rubripes |
| Taxa ID: | 31033 |
| LLPS Type: | LLPS regulator |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Cajal body, Chromatin, Nuclear pore complex, Nuclear speckle, Nucleolus, Centrosome/Spindle pole body, Stress granule, Postsynaptic density, Others | Predicted from orthologs | (View) |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSTRUT00000037194.2 | ENSTRUP00000037062.2 |
| Ensembl | ENSTRUT00000053032.1 | ENSTRUP00000049295.1 |
| UniProt | A0A3B5K7E3, A0A3B5K7E3_TAKRU |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MSESQNDKLY KAEYAKSGRA SCKKCKENIA KDSLRMAIMV QSPMFDGKVP HWHHFSCFWQ 60 61 RAAAQSTSDI DGFSGLRWED QEKIKKAVES GGATGGGTDS KSGAKEEKTL NEFAVEYAKS 120 121 NRSTCKGCEQ KIEKDQIRVS KKSVDPEKPQ LGLIDRWYHT ACFVSWREEL VFKPEYNASQ 180 181 LKGFSNLRAE DKEELKRKLP SIKTEGKRKS DEVDGVSKKK KKEEEEERKK LEEQLKTQSQ 240 241 LIWGIKDKLN RFCSINDMKE LLIANGQDVP SGESNVLDCL ADGMSFGALE PCSECTGQLV 300 301 FKGDAYYCTG NISAWTKCVN KTTTPKRKDW VTPKEFHEIS FLKKFKFKRQ NRIYPKEAPP 360 361 QTVSAVKTES LASASSVPMS LPEGAPPDKP LTGMKLVAVG KLSKNKDDIK AAVEELGGKI 420 421 TGTANKASLC LSSKKELEKM TKKMEEVKDA GVRVVSEDFL TDIKSSGKDL QELVSLHTIS 480 481 PWGAEVKVES QAQPVASKSG AMAAKSTGKV KEEEGGSKSK KMKLTVKGGA AVDPDSGLEN 540 541 SAHVLEQGGK MYSATLGLVD IVRGTNSYYK LQLLEDDVQK RYWVFRSWGR VGTTIGGNKL 600 601 DKFSDKNSAM NNFLTVYKEK TGNEWSCSNF TKYPNKFYPL EIDYGQDEEA VKRLTATAGT 660 661 KSKLAKPIQE LIKMIFDVES MKKAMVEFEI DLQKMPLGKL SKRQIQSAYA LLTEVHQAVS 720 721 DSLPEAQILD LSNRFYTLIP HDFGMKKPPL LNNLNYIQAK VQMLDNLLDI EVAYSLLRGG 780 781 AQDNENDPID INYEKLKTKI EVVDKSAKEA DIILQYVKNT HAATHNTYTL EVQEIFKIRR 840 841 EGEHQRYRPF EELHNRQLLW HGSRATNYAG IMSQGLRIAP PEAPVTGYMF GKGVYFADMV 900 901 SKSANYCHTS QSEPVGFLLL AEVALGNMHE LKKASHITKL PKGKHSVKGL GRTAPDPSAT 960 961 VTLDGVQVPL GNGVNTNIDD TSLLYNEYPL NKAPFILICC IITSIVESQT LYKGLSFFPS 1020 1021 SCALCHLYCL FSLTASPPGI SCMMSHR 1047 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGTCGGAAT CTCAGAACGA CAAGCTCTAC AAAGCGGAAT ATGCCAAGAG CGGCCGCGCC 60 61 TCGTGTAAAA AATGCAAAGA AAACATAGCC AAAGACTCGC TGAGGATGGC CATCATGGTG 120 121 CAGTCCCCCA TGTTTGATGG GAAAGTCCCG CACTGGCACC ACTTCTCGTG CTTCTGGCAG 180 181 CGAGCAGCAG CTCAATCGAC TTCCGACATT GATGGGTTTT CCGGCCTGCG CTGGGAGGAC 240 241 CAGGAGAAGA TCAAGAAGGC CGTCGAAAGC GGGGGCGCGA CGGGAGGAGG AACGGACTCA 300 301 AAGAGTGGAG CGAAAGAAGA GAAGACATTA AACGAATTTG CGGTCGAATA TGCCAAATCG 360 361 AACCGAAGCA CATGCAAAGG TTGTGAGCAG AAAATAGAAA AGGATCAGAT TCGGGTGTCA 420 421 AAGAAATCCG TTGACCCGGA GAAACCGCAG CTCGGCCTGA TTGACCGCTG GTACCACACA 480 481 GCGTGCTTCG TGAGCTGGAG GGAGGAACTG GTCTTCAAAC CCGAGTACAA CGCCTCCCAG 540 541 CTGAAGGGAT TCAGCAATCT ACGGGCAGAA GACAAGGAGG AACTTAAGAG GAAGCTCCCA 600 601 TCAATCAAAA CGGAAGGGAA GCGCAAATCC GATGAGGTGG ACGGCGTCTC AAAGAAAAAG 660 661 AAGAAGGAGG AGGAGGAAGA GAGGAAGAAG CTGGAGGAGC AGCTGAAGAC TCAAAGTCAG 720 721 CTCATTTGGG GAATTAAGGA CAAGTTGAAC AGATTCTGTT CCATTAATGA CATGAAAGAG 780 781 CTGCTGATTG CAAATGGCCA GGATGTTCCT TCAGGAGAGT CCAATGTGTT GGACTGCCTG 840 841 GCTGATGGCA TGTCCTTTGG TGCCCTTGAG CCCTGCAGTG AGTGTACTGG CCAGTTGGTG 900 901 TTCAAGGGCG ATGCTTATTA CTGTACAGGC AACATCTCAG CCTGGACAAA GTGCGTTAAC 960 961 AAGACCACCA CACCCAAACG CAAAGACTGG GTGACCCCCA AGGAATTCCA TGAAATTTCC 1020 1021 TTCCTGAAGA AATTCAAGTT CAAGAGACAG AACAGGATTT ACCCCAAAGA AGCTCCGCCC 1080 1081 CAAACAGTCA GTGCGGTCAA AACTGAATCC TTAGCCAGTG CATCCAGCGT CCCGATGAGT 1140 1141 CTGCCAGAGG GAGCGCCTCC AGACAAGCCT CTCACTGGCA TGAAGCTGGT GGCTGTGGGC 1200 1201 AAGCTGAGCA AGAACAAGGA TGACATTAAG GCTGCTGTGG AGGAGCTGGG TGGGAAGATC 1260 1261 ACTGGAACAG CCAACAAGGC CTCGCTCTGC CTCAGCTCTA AGAAGGAGCT GGAGAAGATG 1320 1321 ACAAAGAAAA TGGAAGAAGT GAAAGATGCA GGGGTGCGCG TGGTCTCCGA AGACTTCCTC 1380 1381 ACAGATATCA AGTCGTCGGG TAAAGACCTT CAGGAGCTGG TGTCCCTGCA CACCATCTCT 1440 1441 CCCTGGGGGG CAGAGGTCAA AGTGGAGAGT CAGGCACAGC CCGTGGCTTC AAAGTCAGGG 1500 1501 GCAATGGCCG CCAAGAGCAC GGGCAAGGTC AAAGAAGAAG AAGGTGGAAG CAAAAGCAAG 1560 1561 AAGATGAAAC TAACTGTGAA AGGTGGAGCT GCTGTGGATC CAGATTCAGG TCTGGAAAAC 1620 1621 AGTGCACATG TCCTTGAGCA GGGCGGAAAG ATGTACAGCG CCACACTGGG TTTGGTGGAC 1680 1681 ATCGTCAGAG GAACCAACTC CTACTACAAA CTACAGCTGC TGGAGGACGA TGTTCAGAAG 1740 1741 AGGTACTGGG TGTTCAGGTC GTGGGGCAGA GTGGGCACCA CCATCGGAGG CAACAAGCTG 1800 1801 GACAAGTTCA GTGACAAGAA CTCTGCCATG AACAACTTCC TGACCGTCTA CAAAGAGAAG 1860 1861 ACTGGTAACG AGTGGAGCTG CTCCAATTTC ACCAAATATC CCAACAAGTT CTACCCCCTG 1920 1921 GAGATCGACT ATGGACAGGA TGAGGAAGCA GTGAAGAGGT TGACGGCCAC AGCAGGGACC 1980 1981 AAGTCCAAGC TGGCCAAACC CATACAGGAG CTGATCAAGA TGATCTTCGA TGTGGAGAGC 2040 2041 ATGAAGAAGG CCATGGTGGA GTTTGAGATT GACCTCCAGA AGATGCCGCT GGGGAAGCTG 2100 2101 AGTAAGAGGC AGATCCAGAG CGCGTATGCT CTCCTCACTG AAGTCCATCA GGCTGTGTCA 2160 2161 GACTCACTGC CCGAGGCCCA GATATTGGAT CTGTCCAATC GTTTCTACAC CTTGATCCCT 2220 2221 CACGACTTCG GTATGAAGAA ACCACCGCTG CTCAACAATC TGAACTACAT TCAGGCGAAG 2280 2281 GTTCAGATGC TGGACAACCT GCTGGACATC GAGGTGGCGT ACAGCCTACT GAGAGGAGGG 2340 2341 GCCCAGGACA ACGAGAATGA CCCCATCGAC ATCAACTATG AGAAACTCAA AACCAAAATC 2400 2401 GAGGTCGTTG ACAAGTCTGC CAAGGAGGCT GATATTATCC TGCAGTATGT CAAGAACACC 2460 2461 CACGCTGCCA CACACAACAC CTACACACTG GAAGTGCAAG AAATCTTCAA AATACGGCGA 2520 2521 GAGGGGGAGC ACCAGCGTTA CCGTCCATTC GAAGAGTTGC ACAACCGGCA GCTCCTGTGG 2580 2581 CACGGCTCTC GCGCCACCAA CTACGCAGGT ATAATGTCTC AGGGTCTCCG CATCGCCCCG 2640 2641 CCAGAGGCTC CAGTGACGGG TTACATGTTC GGCAAAGGTG TGTACTTTGC CGACATGGTG 2700 2701 TCCAAGAGTG CAAACTACTG TCACACTTCC CAGTCAGAAC CCGTAGGTTT CCTGCTGCTG 2760 2761 GCTGAGGTCG CCCTCGGCAA CATGCACGAA CTGAAAAAGG CCTCACACAT TACAAAACTA 2820 2821 CCCAAAGGAA AACACAGCGT TAAAGGTTTG GGAAGAACCG CCCCTGATCC AAGTGCCACT 2880 2881 GTCACTCTGG ACGGAGTGCA AGTGCCTCTG GGAAATGGAG TCAACACAAA CATAGATGAC 2940 2941 ACCAGTCTGT TGTACAACGA GTATATCGTG TATGATGTCG CACAGATAAA CTTAAAGTAT 3000 3001 CTCCTGAAGG TCAGATTTAA TTATCAGACG TCCCTGTGGT GA 3042 |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Ten-0621 | Tetraodon nigroviridis | 91.47 | 0.0 | 1822 |
| LLPS-Scm-0310 | Scophthalmus maximus | 87.56 | 0.0 | 1723 |
| LLPS-Orn-0528 | Oreochromis niloticus | 87.16 | 0.0 | 1713 |
| LLPS-Xim-1441 | Xiphophorus maculatus | 86.46 | 0.0 | 1687 |
| LLPS-Gaa-1409 | Gasterosteus aculeatus | 86.38 | 0.0 | 1677 |
| LLPS-Pof-0563 | Poecilia formosa | 85.56 | 0.0 | 1696 |
| LLPS-Orl-0854 | Oryzias latipes | 85.45 | 0.0 | 1674 |
| LLPS-Dar-2001 | Danio rerio | 81.05 | 0.0 | 1560 |
| LLPS-Scf-1248 | Scleropages formosus | 80.38 | 0.0 | 1592 |
| LLPS-Icp-0885 | Ictalurus punctatus | 79.56 | 0.0 | 1585 |
| LLPS-Asm-1670 | Astyanax mexicanus | 79.22 | 0.0 | 1556 |
| LLPS-Leo-2017 | Lepisosteus oculatus | 78.41 | 0.0 | 1535 |
| LLPS-Myl-1161 | Myotis lucifugus | 75.35 | 0.0 | 682 |
| LLPS-Nol-0871 | Nomascus leucogenys | 72.41 | 0.0 | 582 |
| LLPS-Gaga-3404 | Gallus gallus | 72.0 | 0.0 | 1381 |
| LLPS-Fia-1185 | Ficedula albicollis | 71.74 | 0.0 | 1321 |
| LLPS-Tag-1555 | Taeniopygia guttata | 70.92 | 0.0 | 1203 |
| LLPS-Meg-1238 | Meleagris gallopavo | 70.89 | 0.0 | 1321 |
| LLPS-Anp-0454 | Anas platyrhynchos | 70.83 | 0.0 | 1202 |
| LLPS-Anc-1407 | Anolis carolinensis | 70.24 | 0.0 | 1374 |
| LLPS-Cas-2350 | Carlito syrichta | 69.84 | 0.0 | 1238 |
| LLPS-Hos-0574 | Homo sapiens | 69.75 | 0.0 | 1388 |
| LLPS-Aon-0659 | Aotus nancymaae | 69.74 | 0.0 | 1382 |
| LLPS-Orc-1271 | Oryctolagus cuniculus | 69.68 | 0.0 | 1383 |
| LLPS-Mup-1514 | Mustela putorius furo | 69.55 | 0.0 | 1374 |
| LLPS-Ict-1016 | Ictidomys tridecemlineatus | 69.55 | 0.0 | 1392 |
| LLPS-Sah-1247 | Sarcophilus harrisii | 69.5 | 0.0 | 1311 |
| LLPS-Ora-0714 | Ornithorhynchus anatinus | 69.46 | 0.0 | 1316 |
| LLPS-Gog-3860 | Gorilla gorilla | 69.45 | 0.0 | 1386 |
| LLPS-Otg-0901 | Otolemur garnettii | 69.41 | 0.0 | 1380 |
| LLPS-Pat-1871 | Pan troglodytes | 69.35 | 0.0 | 1384 |
| LLPS-Pap-0147 | Pan paniscus | 69.35 | 0.0 | 1384 |
| LLPS-Rhb-0197 | Rhinopithecus bieti | 69.35 | 0.0 | 1379 |
| LLPS-Pes-0866 | Pelodiscus sinensis | 69.35 | 0.0 | 1312 |
| LLPS-Paa-0580 | Papio anubis | 69.28 | 0.0 | 1375 |
| LLPS-Sus-0785 | Sus scrofa | 69.25 | 0.0 | 1360 |
| LLPS-Cea-0661 | Cercocebus atys | 69.25 | 0.0 | 1377 |
| LLPS-Mam-2076 | Macaca mulatta | 69.15 | 0.0 | 1375 |
| LLPS-Eqc-0519 | Equus caballus | 69.15 | 0.0 | 1347 |
| LLPS-Man-0938 | Macaca nemestrina | 69.15 | 0.0 | 1378 |
| LLPS-Maf-0318 | Macaca fascicularis | 69.05 | 0.0 | 1373 |
| LLPS-Poa-0969 | Pongo abelii | 68.91 | 0.0 | 1318 |
| LLPS-Xet-2794 | Xenopus tropicalis | 68.85 | 0.0 | 1320 |
| LLPS-Cap-0660 | Cavia porcellus | 68.81 | 0.0 | 1373 |
| LLPS-Mod-1703 | Monodelphis domestica | 68.81 | 0.0 | 1362 |
| LLPS-Aim-1380 | Ailuropoda melanoleuca | 68.68 | 0.0 | 1320 |
| LLPS-Ova-0602 | Ovis aries | 68.54 | 0.0 | 1353 |
| LLPS-Mea-0170 | Mesocricetus auratus | 68.44 | 0.0 | 1365 |
| LLPS-Fud-2616 | Fukomys damarensis | 68.31 | 0.0 | 1308 |
| LLPS-Fec-2479 | Felis catus | 68.23 | 0.0 | 1302 |
| LLPS-Mum-2146 | Mus musculus | 68.14 | 0.0 | 1368 |
| LLPS-Ran-0216 | Rattus norvegicus | 67.74 | 0.0 | 1350 |
| LLPS-Dio-1683 | Dipodomys ordii | 67.58 | 0.0 | 1293 |
| LLPS-Loa-1001 | Loxodonta africana | 67.51 | 0.0 | 1287 |
| LLPS-Mal-1549 | Mandrillus leucophaeus | 67.33 | 0.0 | 1328 |
| LLPS-Caj-4080 | Callithrix jacchus | 67.11 | 0.0 | 1371 |
| LLPS-Caf-1916 | Canis familiaris | 67.05 | 0.0 | 1255 |
| LLPS-Chs-1123 | Chlorocebus sabaeus | 66.99 | 0.0 | 912 |
| LLPS-Bot-0201 | Bos taurus | 65.71 | 0.0 | 1288 |
| LLPS-Urm-1131 | Ursus maritimus | 62.92 | 0.0 | 1147 |
| LLPS-Cii-1307 | Ciona intestinalis | 58.26 | 5e-177 | 533 |
| LLPS-Sol-0746 | Solanum lycopersicum | 56.18 | 1e-50 | 199 |
| LLPS-Lac-1485 | Latimeria chalumnae | 55.94 | 0.0 | 1013 |
| LLPS-Zem-0161 | Zea mays | 50.85 | 1e-67 | 233 |
| LLPS-Sei-0222 | Setaria italica | 47.27 | 4e-134 | 424 |
| LLPS-Tru-0646 | Triticum urartu | 47.02 | 3e-118 | 379 |
| LLPS-Sem-1013 | Selaginella moellendorffii | 46.74 | 2e-133 | 434 |
| LLPS-Tra-1496 | Triticum aestivum | 44.33 | 2e-108 | 361 |
| LLPS-Cae-0773 | Caenorhabditis elegans | 44.14 | 1e-116 | 389 |
| LLPS-Thc-1222 | Theobroma cacao | 44.05 | 5e-108 | 357 |
| LLPS-Hea-2308 | Helianthus annuus | 43.87 | 2e-106 | 353 |
| LLPS-Ere-0397 | Erinaceus europaeus | 43.51 | 1e-114 | 373 |
| LLPS-Hov-0763 | Hordeum vulgare | 43.31 | 3e-103 | 349 |
| LLPS-Lep-1511 | Leersia perrieri | 43.28 | 1e-106 | 353 |
| LLPS-Ors-0056 | Oryza sativa | 43.04 | 2e-106 | 353 |
| LLPS-Gor-2055 | Gossypium raimondii | 43.01 | 9e-105 | 350 |
| LLPS-Ori-2185 | Oryza indica | 42.86 | 9e-102 | 356 |
| LLPS-Orm-0778 | Oryza meridionalis | 42.86 | 4e-107 | 355 |
| LLPS-Orp-1976 | Oryza punctata | 42.86 | 1e-106 | 354 |
| LLPS-Orbr-2008 | Oryza brachyantha | 42.86 | 1e-106 | 353 |
| LLPS-Brn-3160 | Brassica napus | 42.77 | 4e-105 | 349 |
| LLPS-Viv-0205 | Vitis vinifera | 42.77 | 2e-106 | 350 |
| LLPS-Php-0916 | Physcomitrella patens | 42.63 | 1e-107 | 359 |
| LLPS-Coc-0897 | Corchorus capsularis | 42.62 | 6e-100 | 348 |
| LLPS-Bro-1088 | Brassica oleracea | 42.53 | 3e-106 | 354 |
| LLPS-Sot-1210 | Solanum tuberosum | 42.45 | 4e-106 | 355 |
| LLPS-Orb-1681 | Oryza barthii | 42.41 | 7e-100 | 348 |
| LLPS-Orr-1724 | Oryza rufipogon | 42.41 | 1e-102 | 347 |
| LLPS-Org-1189 | Oryza glaberrima | 42.41 | 2e-104 | 348 |
| LLPS-Pot-0052 | Populus trichocarpa | 42.32 | 2e-106 | 353 |
| LLPS-Brr-0678 | Brassica rapa | 42.32 | 2e-103 | 345 |
| LLPS-Phv-0221 | Phaseolus vulgaris | 42.28 | 6e-107 | 352 |
| LLPS-Arl-2051 | Arabidopsis lyrata | 42.2 | 1e-104 | 348 |
| LLPS-Art-0542 | Arabidopsis thaliana | 42.12 | 1e-104 | 348 |
| LLPS-Amt-0791 | Amborella trichopoda | 42.08 | 5e-107 | 354 |
| LLPS-Glm-0196 | Glycine max | 42.0 | 9e-101 | 336 |
| LLPS-Met-1811 | Medicago truncatula | 41.79 | 2e-103 | 345 |
| LLPS-Cus-0060 | Cucumis sativus | 41.75 | 7e-103 | 344 |
| LLPS-Dac-0097 | Daucus carota | 41.7 | 1e-105 | 352 |
| LLPS-Nia-0607 | Nicotiana attenuata | 41.67 | 3e-102 | 341 |
| LLPS-Brd-0095 | Brachypodium distachyon | 41.42 | 3e-101 | 342 |
| LLPS-Mua-1430 | Musa acuminata | 41.3 | 9e-108 | 352 |
| LLPS-Cis-0896 | Ciona savignyi | 41.09 | 1e-112 | 367 |
| LLPS-Prp-2051 | Prunus persica | 41.04 | 3e-103 | 344 |
| LLPS-Mae-1535 | Manihot esculenta | 40.62 | 2e-97 | 328 |
| LLPS-Drm-0204 | Drosophila melanogaster | 40.12 | 0.0 | 712 |
| LLPS-Sob-0951 | Sorghum bicolor | 39.87 | 4e-93 | 312 |
| LLPS-Orni-1874 | Oryza nivara | 39.71 | 4e-97 | 327 |
| LLPS-Orgl-0958 | Oryza glumaepatula | 39.5 | 2e-96 | 326 |
| LLPS-Tum-0654 | Tuber melanosporum | 37.58 | 3e-73 | 256 |
| LLPS-Asfu-1606 | Aspergillus fumigatus | 37.26 | 2e-76 | 271 |
| LLPS-Nef-1280 | Neosartorya fischeri | 36.33 | 5e-75 | 267 |
| LLPS-Via-0152 | Vigna angularis | 36.24 | 0.0 | 580 |
| LLPS-Asn-0677 | Aspergillus nidulans | 36.04 | 2e-78 | 276 |
| LLPS-Dos-0339 | Dothistroma septosporum | 35.89 | 1e-69 | 250 |
| LLPS-Cogr-0969 | Colletotrichum graminicola | 35.44 | 3e-70 | 254 |
| LLPS-Phn-0556 | Phaeosphaeria nodorum | 34.73 | 9e-66 | 239 |
| LLPS-Ast-1421 | Aspergillus terreus | 34.69 | 5e-68 | 246 |
| LLPS-Beb-0252 | Beauveria bassiana | 34.6 | 9e-70 | 253 |
| LLPS-Aso-1146 | Aspergillus oryzae | 34.56 | 7e-72 | 258 |
| LLPS-Asc-0626 | Aspergillus clavatus | 34.55 | 4e-68 | 246 |
| LLPS-Mao-1004 | Magnaporthe oryzae | 34.52 | 1e-70 | 255 |
| LLPS-Asf-0875 | Aspergillus flavus | 34.36 | 1e-71 | 257 |
| LLPS-Trv-1319 | Trichoderma virens | 33.94 | 7e-70 | 252 |
| LLPS-Trr-1190 | Trichoderma reesei | 33.87 | 1e-71 | 257 |
| LLPS-Asni-0241 | Aspergillus niger | 32.35 | 3e-72 | 258 |